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ZA202202833B - Compound a1, preparation method thereof and application thereof as pranoprofen impurity - Google Patents

Compound a1, preparation method thereof and application thereof as pranoprofen impurity

Info

Publication number
ZA202202833B
ZA202202833B ZA2022/02833A ZA202202833A ZA202202833B ZA 202202833 B ZA202202833 B ZA 202202833B ZA 2022/02833 A ZA2022/02833 A ZA 2022/02833A ZA 202202833 A ZA202202833 A ZA 202202833A ZA 202202833 B ZA202202833 B ZA 202202833B
Authority
ZA
South Africa
Prior art keywords
pranoprofen
impurity
compound
preparation
application
Prior art date
Application number
ZA2022/02833A
Inventor
Xia Ren
Jiayuan Li
Zongyin Liu
Huimin Cao
Original Assignee
Shandong Ruian Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shandong Ruian Pharmaceutical Co Ltd filed Critical Shandong Ruian Pharmaceutical Co Ltd
Publication of ZA202202833B publication Critical patent/ZA202202833B/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D491/00Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04Ortho-condensed systems
    • C07D491/044Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring
    • C07D491/052Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring the oxygen-containing ring being six-membered
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02Column chromatography
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02Column chromatography
    • G01N30/04Preparation or injection of sample to be analysed
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02Column chromatography
    • G01N2030/022Column chromatography characterised by the kind of separation mechanism
    • G01N2030/027Liquid chromatography
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02Column chromatography
    • G01N30/04Preparation or injection of sample to be analysed
    • G01N2030/042Standards
    • G01N2030/047Standards external

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
ZA2022/02833A 2021-05-07 2022-03-09 Compound a1, preparation method thereof and application thereof as pranoprofen impurity ZA202202833B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202110494473.1A CN113214276A (en) 2021-05-07 2021-05-07 Compound A1, preparation method thereof and application thereof as pranoprofen impurity

Publications (1)

Publication Number Publication Date
ZA202202833B true ZA202202833B (en) 2022-06-29

Family

ID=77091340

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA2022/02833A ZA202202833B (en) 2021-05-07 2022-03-09 Compound a1, preparation method thereof and application thereof as pranoprofen impurity

Country Status (2)

Country Link
CN (1) CN113214276A (en)
ZA (1) ZA202202833B (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113429415B (en) * 2021-07-28 2022-08-30 海南碧凯药业有限公司 Preparation method of pranoprofen impurity
CN115677733A (en) * 2022-12-20 2023-02-03 济南宣正药业有限公司 Compound for pranoprofen quality research and preparation method and application thereof

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110655517A (en) * 2019-07-04 2020-01-07 安徽贝克生物制药有限公司 Preparation method of doriravir open-loop impurities and impurities thereof
CN110372713B (en) * 2019-08-15 2022-05-17 广州市汉普医药有限公司 Refining and purifying method of pranoprofen

Also Published As

Publication number Publication date
CN113214276A (en) 2021-08-06

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