YU43306B - Process for obtaining 2-amino-3-benzoyl-phenylacetamides - Google Patents

Process for obtaining 2-amino-3-benzoyl-phenylacetamides

Info

Publication number: YU43306B
Authority: YU; Yugoslavia
Prior art keywords: phenylacetamides; benzoyl; amino; obtaining
Prior art date: 1979-09-26

Application number

YU731/83A

Other versions

YU73183A (en

Inventor

Jr J R Shanklin

D A Shamblee

D A Walsh

Original Assignee

Robins Co Inc A H

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1979-09-26

Filing date

1983-03-28

Publication date

1989-06-30

1983-03-28 Application filed by Robins Co Inc A H filed Critical Robins Co Inc A H

1983-12-31 Publication of YU73183A publication Critical patent/YU73183A/en

1989-06-30 Publication of YU43306B publication Critical patent/YU43306B/en

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
- C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
- C07D295/182—Radicals derived from carboxylic acids
- C07D295/185—Radicals derived from carboxylic acids from aliphatic carboxylic acids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Pain & Pain Management (AREA)
Hematology (AREA)
Diabetes (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Rheumatology (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

YU731/83A 1979-09-26 1983-03-28 Process for obtaining 2-amino-3-benzoyl-phenylacetamides YU43306B (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US7886079A	1979-09-26	1979-09-26

Publications (2)

Publication Number	Publication Date
YU73183A YU73183A (en)	1983-12-31
YU43306B true YU43306B (en)	1989-06-30

Family

ID=22146633

Family Applications (3)

Application Number	Title	Priority Date	Filing Date
YU2450/80A YU41734B (en)	1979-09-26	1980-09-25	Process for preparing 1-amino-3-benzone-pnenylacetamides
YU730/83A YU43305B (en)	1979-09-26	1983-03-28	Process for obtaining 2-amino-3-benzoyl-phenylacetamides
YU731/83A YU43306B (en)	1979-09-26	1983-03-28	Process for obtaining 2-amino-3-benzoyl-phenylacetamides

Family Applications Before (2)

Application Number	Title	Priority Date	Filing Date
YU2450/80A YU41734B (en)	1979-09-26	1980-09-25	Process for preparing 1-amino-3-benzone-pnenylacetamides
YU730/83A YU43305B (en)	1979-09-26	1983-03-28	Process for obtaining 2-amino-3-benzoyl-phenylacetamides

Country Status (36)

Country	Link
JP (1)	JPS5657751A (en)
KR (1)	KR840000763B1 (en)
AT (1)	AT374170B (en)
AU (1)	AU532359B2 (en)
BE (1)	BE885393A (en)
BR (1)	BR8006042A (en)
CA (1)	CA1128512A (en)
CH (1)	CH646138A5 (en)
CS (1)	CS227012B2 (en)
DE (1)	DE3035688A1 (en)
DK (1)	DK154136C (en)
EG (1)	EG15020A (en)
ES (2)	ES495329A0 (en)
FI (1)	FI72967C (en)
FR (1)	FR2465710A1 (en)
GB (1)	GB2059963B (en)
GR (1)	GR70049B (en)
HK (1)	HK59383A (en)
HU (1)	HU183215B (en)
IE (1)	IE50268B1 (en)
IL (1)	IL60999A (en)
IN (3)	IN151313B (en)
IT (1)	IT1133823B (en)
KE (1)	KE3307A (en)
LU (1)	LU82797A1 (en)
MX (1)	MX7159E (en)
NL (1)	NL8005346A (en)
NO (1)	NO152128C (en)
NZ (1)	NZ195061A (en)
PH (1)	PH22628A (en)
PL (1)	PL128998B1 (en)
PT (1)	PT71839B (en)
SE (1)	SE448626B (en)
SG (1)	SG42983G (en)
YU (3)	YU41734B (en)
ZA (1)	ZA805476B (en)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IL61945A (en) *	1980-02-19	1984-09-30	Robins Co Inc A H	2-amino-3-(hydroxy(phenyl)methyl)phenylacetic acids,esters and amides and pharmaceutical compositions containing them
US6646001B2 (en)	1997-12-19	2003-11-11	Alcon Manufacturing, Ltd.	Use of non-steroidal anti-inflammatory agents in combination with prostaglandin FP receptor agonists to treat glaucoma and ocular hypertension
US6066671A (en)	1997-12-19	2000-05-23	Alcon Laboratories, Inc.	Treatment of GLC1A glaucoma with 3-benzoyl-phenylacetic acids, esters, or amides
GB9727523D0 (en)	1997-12-31	1998-02-25	Pharmacia & Upjohn Spa	Alpha-aminoamide derivatives useful as analgesic agents
AR030345A1 (en) *	2000-08-14	2003-08-20	Alcon Inc	METHOD OF TREATMENT OF DISORDERS RELATED TO ANGIOGENESIS
ES2253579T3 (en)	2001-09-03	2006-06-01	Newron Pharmaceuticals S.P.A.	PHARMACEUTICAL COMPOSITION INCLUDING GABAPENTINA OR AN ANALOG OF HER AND AN ALPHA-AMINOAMIDE AND ITS ANALGESIC USE.
EP1438956A1 (en)	2003-01-16	2004-07-21	Newron Pharmaceuticals S.p.A.	Alpha-aminoamide derivatives useful as antimigraine agents
CZ301776B6 (en) *	2009-06-08	2010-06-16	Farmak, A.S.	Process for preparing 2-amino-3-benzoylphenylacetamide (nepafenac) with minimum by-products
CN112794809B (en) *	2019-11-14	2023-12-29	南京济群医药科技股份有限公司	Preparation method of high-purity nepafenac intermediate

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB1226344A (en) *	1967-07-31	1971-03-24
SE400966B (en) *	1975-08-13	1978-04-17	Robins Co Inc A H	PROCEDURE FOR PREPARING 2-AMINO-3- (OR 5-) BENZOYL-PHENYLETIC ACIDS
IL61945A (en) *	1980-02-19	1984-09-30	Robins Co Inc A H	2-amino-3-(hydroxy(phenyl)methyl)phenylacetic acids,esters and amides and pharmaceutical compositions containing them

1980
- 1980-09-04 ZA ZA00805476A patent/ZA805476B/en unknown
- 1980-09-08 IL IL60999A patent/IL60999A/en unknown
- 1980-09-08 AU AU62116/80A patent/AU532359B2/en not_active Ceased
- 1980-09-11 CS CS806196A patent/CS227012B2/en unknown
- 1980-09-17 IE IE1946/80A patent/IE50268B1/en unknown
- 1980-09-20 EG EG80573A patent/EG15020A/en active
- 1980-09-22 DE DE19803035688 patent/DE3035688A1/en active Granted
- 1980-09-22 GR GR62936A patent/GR70049B/el unknown
- 1980-09-22 BR BR8006042A patent/BR8006042A/en unknown
- 1980-09-23 AT AT0474580A patent/AT374170B/en not_active IP Right Cessation
- 1980-09-23 PH PH24613A patent/PH22628A/en unknown
- 1980-09-24 LU LU82797A patent/LU82797A1/en unknown
- 1980-09-24 SE SE8006668A patent/SE448626B/en not_active IP Right Cessation
- 1980-09-24 FI FI803002A patent/FI72967C/en not_active IP Right Cessation
- 1980-09-25 GB GB8030955A patent/GB2059963B/en not_active Expired
- 1980-09-25 BE BE0/202226A patent/BE885393A/en not_active IP Right Cessation
- 1980-09-25 PT PT71839A patent/PT71839B/en unknown
- 1980-09-25 FR FR8020596A patent/FR2465710A1/en active Granted
- 1980-09-25 NO NO802834A patent/NO152128C/en unknown
- 1980-09-25 CH CH719180A patent/CH646138A5/en not_active IP Right Cessation
- 1980-09-25 NL NL8005346A patent/NL8005346A/en not_active Application Discontinuation
- 1980-09-25 MX MX809050U patent/MX7159E/en unknown
- 1980-09-25 YU YU2450/80A patent/YU41734B/en unknown
- 1980-09-25 ES ES495329A patent/ES495329A0/en active Granted
- 1980-09-25 HU HU802347A patent/HU183215B/en not_active IP Right Cessation
- 1980-09-25 CA CA361,068A patent/CA1128512A/en not_active Expired
- 1980-09-25 PL PL1980226919A patent/PL128998B1/en unknown
- 1980-09-25 KR KR1019800003740A patent/KR840000763B1/en active
- 1980-09-25 DK DK405780A patent/DK154136C/en not_active IP Right Cessation
- 1980-09-26 JP JP13415280A patent/JPS5657751A/en active Granted
- 1980-09-26 NZ NZ195061A patent/NZ195061A/en unknown
- 1980-09-26 IT IT24948/80A patent/IT1133823B/en active
- 1980-09-26 IN IN1092/CAL/80A patent/IN151313B/en unknown
1981
- 1981-06-12 ES ES503019A patent/ES503019A0/en active Granted
1982
- 1982-12-30 IN IN1509/CAL/82A patent/IN156255B/en unknown
- 1982-12-30 IN IN1508/CAL/82A patent/IN156254B/en unknown
1983
- 1983-03-28 YU YU730/83A patent/YU43305B/en unknown
- 1983-03-28 YU YU731/83A patent/YU43306B/en unknown
- 1983-07-19 SG SG42983A patent/SG42983G/en unknown
- 1983-07-21 KE KE3307A patent/KE3307A/en unknown
- 1983-11-24 HK HK593/83A patent/HK59383A/en unknown

Also Published As

Publication number	Publication date
IT8024948A0 (en)	1980-09-26
PT71839A (en)	1980-10-01
IE50268B1 (en)	1986-03-19
JPH0141616B2 (en)	1989-09-06
PL226919A1 (en)	1982-02-01
MX7159E (en)	1987-12-02
GB2059963A (en)	1981-04-29
KR830004210A (en)	1983-07-06
KE3307A (en)	1983-08-19
GB2059963B (en)	1983-04-20
DK154136C (en)	1989-03-06
IL60999A0 (en)	1980-11-30
IN156254B (en)	1985-06-08
NZ195061A (en)	1984-04-27
AT374170B (en)	1984-03-26
ZA805476B (en)	1981-11-25
CH646138A5 (en)	1984-11-15
ES8200329A1 (en)	1981-10-16
FI803002A (en)	1981-03-27
YU245080A (en)	1983-09-30
NL8005346A (en)	1981-03-30
CS227012B2 (en)	1984-04-16
DE3035688C2 (en)	1990-05-17
IL60999A (en)	1984-05-31
YU43305B (en)	1989-06-30
BE885393A (en)	1981-01-16
PH22628A (en)	1988-10-28
SE8006668L (en)	1981-03-27
YU41734B (en)	1987-12-31
ATA474580A (en)	1983-08-15
FR2465710B1 (en)	1984-10-12
ES8204715A1 (en)	1982-05-01
SE448626B (en)	1987-03-09
YU73183A (en)	1983-12-31
JPS5657751A (en)	1981-05-20
DK154136B (en)	1988-10-17
SG42983G (en)	1985-01-11
FI72967B (en)	1987-04-30
IT1133823B (en)	1986-07-24
EG15020A (en)	1985-03-31
AU6211680A (en)	1981-04-02
PT71839B (en)	1981-06-25
NO152128C (en)	1985-08-07
CA1128512A (en)	1982-07-27
HU183215B (en)	1984-04-28
YU73083A (en)	1983-12-31
BR8006042A (en)	1981-04-07
ES503019A0 (en)	1982-05-01
HK59383A (en)	1983-12-02
IN151313B (en)	1983-03-26
FR2465710A1 (en)	1981-03-27
DE3035688A1 (en)	1981-04-16
FI72967C (en)	1987-08-10
DK405780A (en)	1981-03-27
NO802834L (en)	1981-03-27
ES495329A0 (en)	1981-10-16
IE801946L (en)	1981-03-26
NO152128B (en)	1985-04-29
GR70049B (en)	1982-07-26
PL128998B1 (en)	1984-03-31
AU532359B2 (en)	1983-09-29
LU82797A1 (en)	1982-05-10
KR840000763B1 (en)	1984-06-08
IN156255B (en)	1985-06-08

Publication	Publication Date	Title
YU3180A (en)	1983-10-31	Process for obtaining 2-penem compounds
YU11380A (en)	1983-04-30	Process for obtaining n-benzyl-imidazole
YU136780A (en)	1983-10-31	Process for obtaining new 3-thiovinyl-cephalosporins
YU136980A (en)	1983-10-31	Process for obtaining new vinyl-3-cephalosporins
YU65680A (en)	1983-02-28	Process for obtaining 9-amino-alkylfluorene
YU42824B (en)	1988-12-31	Process for obtaining new substituted pyrolidines
YU177880A (en)	1983-12-31	Process for obtaining acyl-carbamides
YU41208B (en)	1986-12-31	Process for obtaining thiazolylidene - oxo -propionitrile
YU43305B (en)	1989-06-30	Process for obtaining 2-amino-3-benzoyl-phenylacetamides
DE3061037D1 (en)	1982-12-09	Process for preparing dimethylaminosilanes
YU13180A (en)	1983-01-21	Process for obtaining spiro-quinolyl-hydantoin
DE3060089D1 (en)	1982-01-28	Process for preparing 1-amino-2-phenoxy-4-hydroxy-anthraquinone
YU283382A (en)	1985-03-20	Process for obtaining pure chlorocyan
YU108580A (en)	1983-02-28	Process for obtaining alkoxyalkylidene hydrazinopyridazine
YU44734B (en)	1991-02-28	Process for obtaining 3-halogen-cephalosporin iminohalogenids
YU259680A (en)	1983-01-21	Process for obtaining acylcarbamides
GB2052495B (en)	1983-06-08	Process for making hexafluorotriallylisocyanurate
YU63980A (en)	1983-02-28	Process for obtaining n-sulfinyl-carbamates
YU276480A (en)	1983-02-28	Process for obtaining omega-lactams
DE3060850D1 (en)	1982-11-04	Process for preparing naphthalenesulphochloride
YU43221B (en)	1989-06-30	Process for obtaining imidazobenzodiazepine
YU310680A (en)	1983-04-30	Process for obtaining vanadyl-hydrate
YU90680A (en)	1983-02-28	Process for obtaining hydroxyimino-substituted aminoacetonitriles
YU114983A (en)	1986-08-31	Process for making hydrocyanide
YU297780A (en)	1983-02-28	Process for obtaining glucoso-isomerase