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YU283173A - Improved process for the isolation of cephalosporin c - Google Patents

Improved process for the isolation of cephalosporin c

Info

Publication number
YU283173A
YU283173A YU02831/73A YU283173A YU283173A YU 283173 A YU283173 A YU 283173A YU 02831/73 A YU02831/73 A YU 02831/73A YU 283173 A YU283173 A YU 283173A YU 283173 A YU283173 A YU 283173A
Authority
YU
Yugoslavia
Prior art keywords
cephalosporin
isolation
improved process
improved
Prior art date
Application number
YU02831/73A
Other languages
English (en)
Inventor
B G Jackson
M C Stamper
E M Bottorff
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US00306130A external-priority patent/US3843642A/en
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of YU283173A publication Critical patent/YU283173A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/02—Preparation
    • C07D501/12—Separation; Purification
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/22—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with radicals containing only hydrogen and carbon atoms, attached in position 3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/542—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/545—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Cephalosporin Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
YU02831/73A 1972-11-13 1973-10-31 Improved process for the isolation of cephalosporin c YU283173A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US00306130A US3843642A (en) 1972-11-13 1972-11-13 Cephalosporin c derivatives
US00398725A US3853863A (en) 1972-11-13 1973-09-19 Cephalosporin c isolation process

Publications (1)

Publication Number Publication Date
YU283173A true YU283173A (en) 1982-02-28

Family

ID=26974991

Family Applications (1)

Application Number Title Priority Date Filing Date
YU02831/73A YU283173A (en) 1972-11-13 1973-10-31 Improved process for the isolation of cephalosporin c

Country Status (24)

Country Link
US (1) US3853863A (fr)
JP (1) JPS5721318B2 (fr)
KR (1) KR780000012B1 (fr)
AR (1) AR202466A1 (fr)
AT (1) AT327386B (fr)
AU (1) AU471843B2 (fr)
CA (1) CA1016163A (fr)
CH (1) CH599224A5 (fr)
CS (1) CS192506B2 (fr)
DD (1) DD112653A5 (fr)
DE (1) DE2356122C2 (fr)
ES (1) ES420336A1 (fr)
FR (1) FR2207140B1 (fr)
GB (1) GB1444575A (fr)
HU (1) HU167596B (fr)
IE (1) IE38382B1 (fr)
IL (1) IL43560A (fr)
NL (1) NL180106C (fr)
PH (1) PH9509A (fr)
PL (1) PL91577B1 (fr)
RO (1) RO63260A (fr)
SE (1) SE409713B (fr)
SU (1) SU603343A3 (fr)
YU (1) YU283173A (fr)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2458554A1 (de) * 1974-01-03 1975-07-10 Lepetit Spa Neues verfahren fuer die gewinnung von cephalosporin c aus einer fermentationsbruehe
GB1489231A (en) * 1974-02-20 1977-10-19 Alfa Farmaceutici Spa Process for the recovery of cephalosporin c and derivatives thereof
JPS557438B2 (fr) * 1974-02-22 1980-02-25
US4168268A (en) * 1977-03-01 1979-09-18 Merck & Co., Inc. Process for isolating thienamycin
US4137405A (en) * 1977-07-28 1979-01-30 Merck & Co., Inc. Isolation of antibiotic Cephamycin C
FR2404642A1 (fr) * 1977-09-29 1979-04-27 Roussel Uclaf Nouveau derive de la cephalosporine c, procede de preparation et application du nouveau produit a la preparation de l'acide 7-amino cephalosporanique
AT367060B (de) * 1979-01-25 1982-05-25 Biochemie Gmbh Verfahren zur herstellung neuer cephalosporinderivate
JPS58143751A (ja) * 1982-02-19 1983-08-26 日本電熱株式会社 排便装置付ベツト
US5512454A (en) * 1994-02-03 1996-04-30 Bristol-Myers Squibb Company Enzymatic acylation of 3-hydroxymethyl cephalosporins

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3227709A (en) * 1961-11-28 1966-01-04 Merck & Co Inc Derivatives of cephalosporin c and process
US3234222A (en) * 1962-02-16 1966-02-08 Ciba Geigy Corp Preparation of 7-acylaminocephalosporanic acids
CH481142A (de) * 1966-12-05 1969-11-15 Ciba Geigy Verfahren zur Isolierung von Cephalosporin C
GB1311268A (en) * 1971-01-26 1973-03-28 Pfizer Process for the isolation of n-benzoyl cephalosporin c

Also Published As

Publication number Publication date
AU6155573A (en) 1975-04-24
DE2356122A1 (de) 1974-05-22
IL43560A (en) 1976-09-30
PL91577B1 (fr) 1977-03-31
IE38382L (en) 1974-05-13
AT327386B (de) 1976-01-26
NL180106B (nl) 1986-08-01
CS192506B2 (en) 1979-08-31
FR2207140B1 (fr) 1977-06-03
ES420336A1 (es) 1976-06-16
AU471843B2 (en) 1976-05-06
JPS5721318B2 (fr) 1982-05-06
NL180106C (nl) 1987-01-02
IE38382B1 (en) 1978-03-01
DD112653A5 (fr) 1975-04-20
SE409713B (sv) 1979-09-03
ATA954273A (de) 1975-04-15
PH9509A (en) 1976-01-09
NL7315480A (fr) 1974-05-15
SU603343A3 (ru) 1978-04-15
HU167596B (fr) 1975-11-28
AR202466A1 (es) 1975-06-13
JPS49133595A (fr) 1974-12-21
FR2207140A1 (fr) 1974-06-14
GB1444575A (en) 1976-08-04
CH599224A5 (fr) 1978-05-12
KR780000012B1 (en) 1978-03-04
DE2356122C2 (de) 1983-12-22
CA1016163A (fr) 1977-08-23
RO63260A (fr) 1978-06-15
US3853863A (en) 1974-12-10
IL43560A0 (en) 1974-03-14

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