WO2024191972A3 - Anti-lipocalin-2 antibodies and uses thereof - Google Patents
Anti-lipocalin-2 antibodies and uses thereof Download PDFInfo
- Publication number
- WO2024191972A3 WO2024191972A3 PCT/US2024/019489 US2024019489W WO2024191972A3 WO 2024191972 A3 WO2024191972 A3 WO 2024191972A3 US 2024019489 W US2024019489 W US 2024019489W WO 2024191972 A3 WO2024191972 A3 WO 2024191972A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- antibodies
- antigen
- binding fragments
- lipocalin
- lcn2
- Prior art date
Links
- 239000000427 antigen Substances 0.000 abstract 5
- 102000036639 antigens Human genes 0.000 abstract 5
- 108091007433 antigens Proteins 0.000 abstract 5
- 239000012634 fragment Substances 0.000 abstract 5
- 102100035405 Neutrophil gelatinase-associated lipocalin Human genes 0.000 abstract 2
- 101001023833 Homo sapiens Neutrophil gelatinase-associated lipocalin Proteins 0.000 abstract 1
- 108010051335 Lipocalin-2 Proteins 0.000 abstract 1
- 239000000611 antibody drug conjugate Substances 0.000 abstract 1
- 229940049595 antibody-drug conjugate Drugs 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 102000040430 polynucleotide Human genes 0.000 abstract 1
- 108091033319 polynucleotide Proteins 0.000 abstract 1
- 239000002157 polynucleotide Substances 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
- 239000013598 vector Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/40—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against enzymes
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- Mycology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Abstract
This application relates to antibodies or antigen-binding fragments thereof that bind to Lipocalin-2(LCN2) protein, antibody -drug conjugates comprising such antibodies or antigen-binding fragments, as well as polynucleotides and vectors that encode for such antibodies or antigen-binding fragments. This application further relates to methods of producing the antibodies or antigen-binding fragments and using the antibodies or antigen-binding fragments for treatment of diseases.
Applications Claiming Priority (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202363451869P | 2023-03-13 | 2023-03-13 | |
| US63/451,869 | 2023-03-13 | ||
| US202363537089P | 2023-09-07 | 2023-09-07 | |
| US63/537,089 | 2023-09-07 | ||
| US202463621821P | 2024-01-17 | 2024-01-17 | |
| US63/621,821 | 2024-01-17 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| WO2024191972A2 WO2024191972A2 (en) | 2024-09-19 |
| WO2024191972A3 true WO2024191972A3 (en) | 2024-10-31 |
Family
ID=92756351
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PCT/US2024/019489 WO2024191972A2 (en) | 2023-03-13 | 2024-03-12 | Anti-lipocalin-2 antibodies and uses thereof |
Country Status (1)
| Country | Link |
|---|---|
| WO (1) | WO2024191972A2 (en) |
-
2024
- 2024-03-12 WO PCT/US2024/019489 patent/WO2024191972A2/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| WO2024191972A2 (en) | 2024-09-19 |
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| Date | Code | Title | Description |
|---|---|---|---|
| 121 | Ep: the epo has been informed by wipo that ep was designated in this application |
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