WO2016195121A8 - 動物細胞凍結保存液用ガラス化状態安定化剤 - Google Patents
動物細胞凍結保存液用ガラス化状態安定化剤 Download PDFInfo
- Publication number
- WO2016195121A8 WO2016195121A8 PCT/JP2016/071169 JP2016071169W WO2016195121A8 WO 2016195121 A8 WO2016195121 A8 WO 2016195121A8 JP 2016071169 W JP2016071169 W JP 2016071169W WO 2016195121 A8 WO2016195121 A8 WO 2016195121A8
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- animal cell
- cell cryopreservation
- cryopreservation fluid
- vitrification
- stabilizer
- Prior art date
Links
- 210000004102 animal cell Anatomy 0.000 title abstract 5
- 238000005138 cryopreservation Methods 0.000 title abstract 5
- 239000012530 fluid Substances 0.000 title abstract 5
- 238000004017 vitrification Methods 0.000 title abstract 5
- 239000003381 stabilizer Substances 0.000 title abstract 4
- 150000001875 compounds Chemical class 0.000 abstract 5
- 229920000642 polymer Polymers 0.000 abstract 4
- 230000021523 carboxylation Effects 0.000 abstract 3
- 238000006473 carboxylation reaction Methods 0.000 abstract 3
- 229920001351 ε-poly-L-lysine Polymers 0.000 abstract 3
- NSJAWXMCLJVBPM-UHFFFAOYSA-N 3-butyloxolane-2,5-dione Chemical compound CCCCC1CC(=O)OC1=O NSJAWXMCLJVBPM-UHFFFAOYSA-N 0.000 abstract 2
- RINCXYDBBGOEEQ-UHFFFAOYSA-N succinic anhydride Chemical compound O=C1CCC(=O)O1 RINCXYDBBGOEEQ-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N1/00—Preservation of bodies of humans or animals, or parts thereof
- A01N1/10—Preservation of living parts
- A01N1/12—Chemical aspects of preservation
- A01N1/122—Preservation or perfusion media
- A01N1/125—Freeze protecting agents, e.g. cryoprotectants or osmolarity regulators
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N1/00—Preservation of bodies of humans or animals, or parts thereof
- A01N1/10—Preservation of living parts
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N1/00—Preservation of bodies of humans or animals, or parts thereof
- A01N1/10—Preservation of living parts
- A01N1/16—Physical preservation processes
- A01N1/162—Temperature processes, e.g. following predefined temperature changes over time
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Dentistry (AREA)
- General Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Environmental Sciences (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Polyamides (AREA)
Abstract
(a)ε-ポリ-L-リジンをブチル無水コハク酸と反応させてカルボキシル化した両性高分子化合物;(b)ε-ポリ-L-リジンを、ブチル無水コハク酸及び無水コハク酸と反応させてカルボキシル化した両性高分子化合物;又は(c)ε-ポリ-L-リジンを、式Iで表される化合物と反応させてカルボキシル化した両性高分子化合物、からなる群から選択された両性高分子化合物を含む動物細胞凍結保存液用ガラス化状態安定化剤、及び該ガラス化状態安定化剤を含有する動物細胞凍結保存液によって、優れたガラス化能を有する動物細胞凍結保存液を提供する。
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US15/577,944 US11197473B2 (en) | 2015-05-29 | 2016-07-19 | Vitrified state stabilizing agent for animal cell cryopreservation solution |
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2015-110473 | 2015-05-29 | ||
JP2015110473 | 2015-05-29 | ||
JP2016-023010 | 2016-02-09 | ||
JP2016023010A JP6678931B2 (ja) | 2015-05-29 | 2016-02-09 | 動物細胞凍結保存液用ガラス化状態安定化剤 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2016195121A1 WO2016195121A1 (ja) | 2016-12-08 |
WO2016195121A8 true WO2016195121A8 (ja) | 2017-05-18 |
Family
ID=57442260
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/JP2016/071169 WO2016195121A1 (ja) | 2015-05-29 | 2016-07-19 | 動物細胞凍結保存液用ガラス化状態安定化剤 |
Country Status (2)
Country | Link |
---|---|
US (1) | US11197473B2 (ja) |
WO (1) | WO2016195121A1 (ja) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US11197473B2 (en) | 2015-05-29 | 2021-12-14 | Japan Advanced Institute Of Science And Technology | Vitrified state stabilizing agent for animal cell cryopreservation solution |
WO2017141991A1 (ja) | 2016-02-17 | 2017-08-24 | 国立大学法人北陸先端科学技術大学院大学 | 動物細胞凍結保存液用ガラス化状態安定化剤 |
GB201804233D0 (en) | 2018-03-16 | 2018-05-02 | Univ Warwick | Cryopreserving processes |
CN110495450B (zh) * | 2019-09-24 | 2021-08-03 | 湖南丰晖生物科技有限公司 | 一种细胞冻存运输液及其应用 |
JP2024504936A (ja) * | 2021-01-14 | 2024-02-02 | ヴィトラフィー ライフ サイエンシズ リミテッド | 生物学的材料の保存方法および装置 |
WO2024232422A1 (ja) * | 2023-05-10 | 2024-11-14 | 国立大学法人北陸先端科学技術大学院大学 | タンパク質凝集抑制剤 |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3300474A (en) | 1964-02-12 | 1967-01-24 | Pharmacia Ab | Sucrose ether copolymerizates |
AU723170B2 (en) | 1995-10-19 | 2000-08-17 | Bio-Origyn Llc | Methods and compositions to improve germ cell and embryo survival and function |
CH700956B1 (de) | 2003-05-08 | 2010-11-15 | Cellartis Ab | Gefrierkonservierung menschlicher, von Blastocysten abgeleiteten Stammzellen nach dem Verfahren der Vitrifizierung im geschlossenen Röhrchen. |
CN102124098B (zh) * | 2008-06-27 | 2014-03-12 | 博傲沃德株式会社 | 细胞及组织的冷冻保存用组合物 |
JP5630979B2 (ja) | 2009-08-04 | 2014-11-26 | 株式会社バイオベルデ | 動物幹細胞凍結保存液 |
JP5553332B2 (ja) | 2009-08-12 | 2014-07-16 | 独立行政法人理化学研究所 | 生物材料用ガラス化液、ガラス化キット、及びその利用 |
JP6220108B2 (ja) | 2011-04-04 | 2017-10-25 | 株式会社バイオベルデ | 多能性幹細胞その他の分散浮遊可能な細胞用の凍結保存液および凍結保存法 |
US11197473B2 (en) | 2015-05-29 | 2021-12-14 | Japan Advanced Institute Of Science And Technology | Vitrified state stabilizing agent for animal cell cryopreservation solution |
JP6678931B2 (ja) | 2015-05-29 | 2020-04-15 | 国立大学法人北陸先端科学技術大学院大学 | 動物細胞凍結保存液用ガラス化状態安定化剤 |
-
2016
- 2016-07-19 US US15/577,944 patent/US11197473B2/en active Active
- 2016-07-19 WO PCT/JP2016/071169 patent/WO2016195121A1/ja active Application Filing
Also Published As
Publication number | Publication date |
---|---|
US11197473B2 (en) | 2021-12-14 |
US20180160676A1 (en) | 2018-06-14 |
WO2016195121A1 (ja) | 2016-12-08 |
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