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WO2016195121A8 - 動物細胞凍結保存液用ガラス化状態安定化剤 - Google Patents

動物細胞凍結保存液用ガラス化状態安定化剤 Download PDF

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Publication number
WO2016195121A8
WO2016195121A8 PCT/JP2016/071169 JP2016071169W WO2016195121A8 WO 2016195121 A8 WO2016195121 A8 WO 2016195121A8 JP 2016071169 W JP2016071169 W JP 2016071169W WO 2016195121 A8 WO2016195121 A8 WO 2016195121A8
Authority
WO
WIPO (PCT)
Prior art keywords
animal cell
cell cryopreservation
cryopreservation fluid
vitrification
stabilizer
Prior art date
Application number
PCT/JP2016/071169
Other languages
English (en)
French (fr)
Other versions
WO2016195121A1 (ja
Inventor
和明 松村
雅 鈴木
Original Assignee
国立大学法人北陸先端科学技術大学院大学
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP2016023010A external-priority patent/JP6678931B2/ja
Application filed by 国立大学法人北陸先端科学技術大学院大学 filed Critical 国立大学法人北陸先端科学技術大学院大学
Priority to US15/577,944 priority Critical patent/US11197473B2/en
Publication of WO2016195121A1 publication Critical patent/WO2016195121A1/ja
Publication of WO2016195121A8 publication Critical patent/WO2016195121A8/ja

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Classifications

    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00Preservation of bodies of humans or animals, or parts thereof
    • A01N1/10Preservation of living parts
    • A01N1/12Chemical aspects of preservation
    • A01N1/122Preservation or perfusion media
    • A01N1/125Freeze protecting agents, e.g. cryoprotectants or osmolarity regulators
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00Preservation of bodies of humans or animals, or parts thereof
    • A01N1/10Preservation of living parts
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00Preservation of bodies of humans or animals, or parts thereof
    • A01N1/10Preservation of living parts
    • A01N1/16Physical preservation processes
    • A01N1/162Temperature processes, e.g. following predefined temperature changes over time

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Dentistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Polyamides (AREA)

Abstract

(a)ε-ポリ-L-リジンをブチル無水コハク酸と反応させてカルボキシル化した両性高分子化合物;(b)ε-ポリ-L-リジンを、ブチル無水コハク酸及び無水コハク酸と反応させてカルボキシル化した両性高分子化合物;又は(c)ε-ポリ-L-リジンを、式Iで表される化合物と反応させてカルボキシル化した両性高分子化合物、からなる群から選択された両性高分子化合物を含む動物細胞凍結保存液用ガラス化状態安定化剤、及び該ガラス化状態安定化剤を含有する動物細胞凍結保存液によって、優れたガラス化能を有する動物細胞凍結保存液を提供する。
PCT/JP2016/071169 2015-05-29 2016-07-19 動物細胞凍結保存液用ガラス化状態安定化剤 WO2016195121A1 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
US15/577,944 US11197473B2 (en) 2015-05-29 2016-07-19 Vitrified state stabilizing agent for animal cell cryopreservation solution

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP2015-110473 2015-05-29
JP2015110473 2015-05-29
JP2016-023010 2016-02-09
JP2016023010A JP6678931B2 (ja) 2015-05-29 2016-02-09 動物細胞凍結保存液用ガラス化状態安定化剤

Publications (2)

Publication Number Publication Date
WO2016195121A1 WO2016195121A1 (ja) 2016-12-08
WO2016195121A8 true WO2016195121A8 (ja) 2017-05-18

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/JP2016/071169 WO2016195121A1 (ja) 2015-05-29 2016-07-19 動物細胞凍結保存液用ガラス化状態安定化剤

Country Status (2)

Country Link
US (1) US11197473B2 (ja)
WO (1) WO2016195121A1 (ja)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11197473B2 (en) 2015-05-29 2021-12-14 Japan Advanced Institute Of Science And Technology Vitrified state stabilizing agent for animal cell cryopreservation solution
WO2017141991A1 (ja) 2016-02-17 2017-08-24 国立大学法人北陸先端科学技術大学院大学 動物細胞凍結保存液用ガラス化状態安定化剤
GB201804233D0 (en) 2018-03-16 2018-05-02 Univ Warwick Cryopreserving processes
CN110495450B (zh) * 2019-09-24 2021-08-03 湖南丰晖生物科技有限公司 一种细胞冻存运输液及其应用
JP2024504936A (ja) * 2021-01-14 2024-02-02 ヴィトラフィー ライフ サイエンシズ リミテッド 生物学的材料の保存方法および装置
WO2024232422A1 (ja) * 2023-05-10 2024-11-14 国立大学法人北陸先端科学技術大学院大学 タンパク質凝集抑制剤

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3300474A (en) 1964-02-12 1967-01-24 Pharmacia Ab Sucrose ether copolymerizates
AU723170B2 (en) 1995-10-19 2000-08-17 Bio-Origyn Llc Methods and compositions to improve germ cell and embryo survival and function
CH700956B1 (de) 2003-05-08 2010-11-15 Cellartis Ab Gefrierkonservierung menschlicher, von Blastocysten abgeleiteten Stammzellen nach dem Verfahren der Vitrifizierung im geschlossenen Röhrchen.
CN102124098B (zh) * 2008-06-27 2014-03-12 博傲沃德株式会社 细胞及组织的冷冻保存用组合物
JP5630979B2 (ja) 2009-08-04 2014-11-26 株式会社バイオベルデ 動物幹細胞凍結保存液
JP5553332B2 (ja) 2009-08-12 2014-07-16 独立行政法人理化学研究所 生物材料用ガラス化液、ガラス化キット、及びその利用
JP6220108B2 (ja) 2011-04-04 2017-10-25 株式会社バイオベルデ 多能性幹細胞その他の分散浮遊可能な細胞用の凍結保存液および凍結保存法
US11197473B2 (en) 2015-05-29 2021-12-14 Japan Advanced Institute Of Science And Technology Vitrified state stabilizing agent for animal cell cryopreservation solution
JP6678931B2 (ja) 2015-05-29 2020-04-15 国立大学法人北陸先端科学技術大学院大学 動物細胞凍結保存液用ガラス化状態安定化剤

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Publication number Publication date
US11197473B2 (en) 2021-12-14
US20180160676A1 (en) 2018-06-14
WO2016195121A1 (ja) 2016-12-08

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