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WO2014063111A8 - Drug delivery medical device - Google Patents

Drug delivery medical device Download PDF

Info

Publication number
WO2014063111A8
WO2014063111A8 PCT/US2013/065777 US2013065777W WO2014063111A8 WO 2014063111 A8 WO2014063111 A8 WO 2014063111A8 US 2013065777 W US2013065777 W US 2013065777W WO 2014063111 A8 WO2014063111 A8 WO 2014063111A8
Authority
WO
WIPO (PCT)
Prior art keywords
balloon
pharmaceutical agent
medical device
coating
drug delivery
Prior art date
Application number
PCT/US2013/065777
Other languages
French (fr)
Other versions
WO2014063111A1 (en
Inventor
James B. Mcclain
Charles Douglas Taylor
Meagan M. FAGAN
Original Assignee
Micell Technologies, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Micell Technologies, Inc. filed Critical Micell Technologies, Inc.
Priority to CN201380066590.1A priority Critical patent/CN104994891A/en
Priority to CA2888776A priority patent/CA2888776C/en
Priority to JP2015538086A priority patent/JP2015533305A/en
Priority to EP13847009.1A priority patent/EP2908874A4/en
Priority to US14/437,097 priority patent/US10188772B2/en
Priority to AU2013331003A priority patent/AU2013331003B2/en
Publication of WO2014063111A1 publication Critical patent/WO2014063111A1/en
Publication of WO2014063111A8 publication Critical patent/WO2014063111A8/en
Priority to HK16101611.9A priority patent/HK1213503A1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L29/00—Materials for catheters, medical tubing, cannulae, or endoscopes or for coating catheters
    • A61L29/08—Materials for coatings
    • A61L29/085—Macromolecular materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L29/00—Materials for catheters, medical tubing, cannulae, or endoscopes or for coating catheters
    • A61L29/14—Materials characterised by their function or physical properties, e.g. lubricating compositions
    • A61L29/16—Biologically active materials, e.g. therapeutic substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/60—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special physical form
    • A61L2300/62—Encapsulated active agents, e.g. emulsified droplets
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/60—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special physical form
    • A61L2300/63—Crystals

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Immunology (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Transplantation (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Materials For Medical Uses (AREA)

Abstract

A medical device that releases a pharmaceutical agent to a target site is disclosed. The medical device includes a balloon, and a coating on at least a portion of the balloon. The coating includes particles of a pharmaceutical agent. Each particle of the particles of the pharmaceutical agent is at least partially encapsulated in a polymer material. A method of releasing a pharmaceutical agent at a target site is also disclosed. The method includes the steps of providing a device including a balloon, and a coating on at least a portion of the balloon, the coating including particles of a pharmaceutical agent, and each particle of the pharmaceutical agent is at least partially encapsulated in a polymer material; positioning the device to allow the balloon to reach the target site; and inflating the balloon of the device.
PCT/US2013/065777 2011-10-18 2013-10-18 Drug delivery medical device WO2014063111A1 (en)

Priority Applications (7)

Application Number Priority Date Filing Date Title
CN201380066590.1A CN104994891A (en) 2012-10-18 2013-10-18 Drug delivery medical device
CA2888776A CA2888776C (en) 2012-10-18 2013-10-18 Drug delivery medical device
JP2015538086A JP2015533305A (en) 2012-10-18 2013-10-18 Drug delivery medical device
EP13847009.1A EP2908874A4 (en) 2012-10-18 2013-10-18 Drug delivery medical device
US14/437,097 US10188772B2 (en) 2011-10-18 2013-10-18 Drug delivery medical device
AU2013331003A AU2013331003B2 (en) 2012-10-18 2013-10-18 Drug delivery medical device
HK16101611.9A HK1213503A1 (en) 2012-10-18 2016-02-15 Drug delivery medical device

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201261715768P 2012-10-18 2012-10-18
US61/715,768 2012-10-18

Publications (2)

Publication Number Publication Date
WO2014063111A1 WO2014063111A1 (en) 2014-04-24
WO2014063111A8 true WO2014063111A8 (en) 2014-05-30

Family

ID=50488802

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2013/065777 WO2014063111A1 (en) 2011-10-18 2013-10-18 Drug delivery medical device

Country Status (7)

Country Link
EP (1) EP2908874A4 (en)
JP (1) JP2015533305A (en)
CN (2) CN110935070A (en)
AU (1) AU2013331003B2 (en)
CA (1) CA2888776C (en)
HK (1) HK1213503A1 (en)
WO (1) WO2014063111A1 (en)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007011708A2 (en) 2005-07-15 2007-01-25 Micell Technologies, Inc. Stent with polymer coating containing amorphous rapamycin
EP1909973B1 (en) 2005-07-15 2018-08-22 Micell Technologies, Inc. Polymer coatings containing drug powder of controlled morphology
CA2650590C (en) 2006-04-26 2018-04-03 Micell Technologies, Inc. Coatings containing multiple drugs
CN101678388B (en) 2006-10-23 2013-12-11 米歇尔技术公司 Holder for electrically charging a substrate during coating
US11426494B2 (en) 2007-01-08 2022-08-30 MT Acquisition Holdings LLC Stents having biodegradable layers
WO2008086369A1 (en) 2007-01-08 2008-07-17 Micell Technologies, Inc. Stents having biodegradable layers
CA2688314C (en) 2007-05-25 2013-12-03 Micell Technologies, Inc. Polymer films for medical device coating
NZ588549A (en) 2008-04-17 2013-05-31 Micell Technologies Inc Stents having bioabsorbable layers
US9510856B2 (en) 2008-07-17 2016-12-06 Micell Technologies, Inc. Drug delivery medical device
JP2011528275A (en) 2008-07-17 2011-11-17 ミセル テクノロジーズ，インク． Drug delivery medical device
CN102481195B (en) 2009-04-01 2015-03-25 米歇尔技术公司 Drug delivery medical device
EP2419058B1 (en) 2009-04-17 2018-02-28 Micell Technologies, Inc. Stents having controlled elution
WO2011097103A1 (en) 2010-02-02 2011-08-11 Micell Technologies, Inc. Stent and stent delivery system with improved deliverability
US8795762B2 (en) 2010-03-26 2014-08-05 Battelle Memorial Institute System and method for enhanced electrostatic deposition and surface coatings
CA2797110C (en) 2010-04-22 2020-07-21 Micell Technologies, Inc. Stents and other devices having extracellular matrix coating
CA2805631C (en) 2010-07-16 2018-07-31 Micell Technologies, Inc. Drug delivery medical device
WO2012166819A1 (en) 2011-05-31 2012-12-06 Micell Technologies, Inc. System and process for formation of a time-released, drug-eluting transferable coating
US10117972B2 (en) 2011-07-15 2018-11-06 Micell Technologies, Inc. Drug delivery medical device
US10188772B2 (en) 2011-10-18 2019-01-29 Micell Technologies, Inc. Drug delivery medical device
KR20150143476A (en) 2013-03-12 2015-12-23 미셀 테크놀로지즈, 인코포레이티드 Bioabsorbable biomedical implants
WO2014186532A1 (en) 2013-05-15 2014-11-20 Micell Technologies, Inc. Bioabsorbable biomedical implants
CN105031741A (en) * 2015-03-03 2015-11-11 江苏海泽医疗科技发展有限公司 Medical catheter with anti-infective drug coating and drug slowly-releasing function and preparing method thereof
WO2019079622A1 (en) * 2017-10-18 2019-04-25 Bvw Holding Ag Device with microstructure mediated absorption profile
CN112739392A (en) * 2018-08-01 2021-04-30 波士顿科学国际有限公司 Drug release coating composition
CN113616857B (en) * 2021-08-27 2022-05-31 谱高医疗科技(南京)有限公司 Preparation method of rapamycin drug balloon and rapamycin drug balloon

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020055710A1 (en) * 1998-04-30 2002-05-09 Ronald J. Tuch Medical device for delivering a therapeutic agent and method of preparation
US7682656B2 (en) * 2004-06-14 2010-03-23 Agruim Inc. Process and apparatus for producing a coated product
US7842312B2 (en) * 2005-12-29 2010-11-30 Cordis Corporation Polymeric compositions comprising therapeutic agents in crystalline phases, and methods of forming the same
JP4297221B2 (en) * 2006-02-15 2009-07-15 株式会社ホソカワ粉体技術研究所 Method for producing drug-eluting stent
US20080175887A1 (en) * 2006-11-20 2008-07-24 Lixiao Wang Treatment of Asthma and Chronic Obstructive Pulmonary Disease With Anti-proliferate and Anti-inflammatory Drugs
EP2491962A1 (en) * 2007-01-21 2012-08-29 Hemoteq AG Medical product for treating closures of bodily passages and preventing reclosures
CN101264347A (en) * 2007-11-27 2008-09-17 天津百畅医疗器械科技有限公司 Drug coating applied to balloon surface of balloon catheter balloon for relieving vascular restenosis
CN101161300B (en) * 2007-11-27 2011-03-16 北京美中双和医疗器械有限公司 Arsenic trioxide medicament elution bracket and its preparation method
WO2009096822A1 (en) * 2008-01-30 2009-08-06 Micromuscle Ab Drug delivery devices and methods and applications thereof
US9186439B2 (en) * 2008-03-12 2015-11-17 Anges Mg, Inc. Drug-eluting catheter and method of manufacturing the same
EP2271379B1 (en) * 2008-03-28 2015-11-25 SurModics, Inc. Insertable medical devices having microparticulate-associated elastic substrates and methods for drug delivery
WO2010024898A2 (en) * 2008-08-29 2010-03-04 Lutonix, Inc. Methods and apparatuses for coating balloon catheters
CN102481195B (en) * 2009-04-01 2015-03-25 米歇尔技术公司 Drug delivery medical device
WO2010136604A1 (en) * 2009-05-29 2010-12-02 Dsm Ip Assets B.V. Transfer matrix for transferring a bioactive agent to body tissue
WO2011097103A1 (en) * 2010-02-02 2011-08-11 Micell Technologies, Inc. Stent and stent delivery system with improved deliverability
CA2805631C (en) * 2010-07-16 2018-07-31 Micell Technologies, Inc. Drug delivery medical device
US20120177742A1 (en) * 2010-12-30 2012-07-12 Micell Technologies, Inc. Nanoparticle and surface-modified particulate coatings, coated balloons, and methods therefore
WO2012091680A1 (en) * 2010-12-30 2012-07-05 Nanyang Technological University A device for controlled release of a bioactive agent

Also Published As

Publication number Publication date
EP2908874A1 (en) 2015-08-26
JP2015533305A (en) 2015-11-24
EP2908874A4 (en) 2016-06-22
WO2014063111A1 (en) 2014-04-24
CA2888776A1 (en) 2014-04-24
CN104994891A (en) 2015-10-21
AU2013331003A1 (en) 2015-05-07
HK1213503A1 (en) 2016-07-08
CN110935070A (en) 2020-03-31
CA2888776C (en) 2020-12-29
AU2013331003B2 (en) 2016-11-24

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