WO2013047982A2 - Hydrogel composition for moisturizing skin and enhancing skin elasticity using properties of water - Google Patents

Abstract

The present invention relates to a hydrogel composition for moisturizing skin and enhancing skin elasticity using properties of water. More particularly, the present invention relates to a hydrogel composition enhancing moisture and elasticity of the skin, in which the hydrogel composition utilizes water over time due to hydrogel properties to provide skin care effects, also contains ceramide components of nanoparticles to maintain skin care effects over a long period of time, and induces skin moisturizing, skin elasticity, collagen and elastin synthesis during long-term use of the composition, thereby exhibiting excellent skin care effects. The hydrogel composition for moisturizing skin and enhancing skin elasticity using properties of water according to the present invention, comprises 0.5-3.0 wt% of a gelation polymer, 0.5-10.0 wt% of collagen, 5.0-20.0 wt% of a moisturizer, 0.04-1.0 wt% of a monovalent cationic ingredient for adjusting gel strength, 0.01-0.1 wt% of citric acid which is an acidity regulator, 0.02-0.1 wt% of a sequestering agent, 0.1-1.0 wt% of a solubilizing agent (surfactant), 0.02-0.5 wt% of combined perfumes, 0.2-0.6 wt% of a preserving agent, and the remainder being refined water.

Description

Hydrogel composition for skin moisturizing and skin elasticity improvement

The present invention relates to a hydrogel composition for skin moisturizing and skin elasticity enhancement according to the maturity characteristics, more specifically, the hydration phenomenon over time due to the nature of the prescription hydrogel can not only obtain the cosmetic effect of the skin, but also nanoparticles By containing the ceramide component hwahwa the effect can be maintained for a long time, it relates to a hydrogel composition exhibiting excellent skin moisturizing and elasticity effect by inducing skin moisturizing, elasticity, collagen and elastin synthesis, etc. in the long-term use.

In order to develop drug carriers using hydrogels, various researches and developments using stimulus-sensitive block copolymers (temperature, pH, light, electric field, magnetic field, etc.) have been actively conducted. Hydrogels are used as dressings for wounds or lesions, as biological response modifiers, whereby dried hydrogels of hydrophilic-hygroscopic polymers or, more specifically, lyophilized hydrogels of polymeric carbohydrates. As such, hydrogels have been used mainly for the purpose of biopharmaceutical delivery systems or wound healing of skin, but in recent years, hydrogels have been applied to cosmetics.

Hydrogels, which are biopharmaceutical carriers, mainly use hydrophilic polymers to facilitate skin penetration. As a raw material for forming a hydrogel, a polyethylene called conventional Pluronic is obtained by using a copolymer of polyarakelene glycol and polylactide or polyglycolide, polycaprolactone, which is a biodegradable polyester polymer. Glycol and polyethylene oxide-polypropylene oxide-polyethylene oxide block copolymer are also used. These polymers are used to develop drug carrier hydrogels in the body.

Hydrogels developed for wound healing and the like serve to protect the wound from further trauma, environmental factors that slow down the healing process, or both. Mannan, including polysaccharides such as glucomannan and galactomannan, is used, which is widely used as a binder for the regulation of food tissues. Some encounters also show significant therapeutic properties.

Hydrogels used in cosmetics have been applied to the fields of skin care, skin care, skin treatment and the like. Mainly develops branched gelling polymer and electrolytic polymer according to product type. This is to make the delivery of drugs to the skin easy and rapid as affinity hydrogel. Examples of the branched gelling polymer include galactomannan, glucomannan, guar gum, locust bean gum, and pluronic. As electrolytic gelling polymers, agar, algin, carrageenan, xanthan and gellan are used. They can further formulate ingredients such as blends and moisturizers at appropriate temperatures to enhance skin intimacy, adhesion, and cosmetic effects.

Such polymers used in the hydrogel of cosmetics, such as gum, are rubbery substances present in plants or microorganisms, rubbery substances and mucus substances secreted from plants or microorganisms, and have high apparent viscosity and polysaccharides having unique properties. Say. Blacks are structurally hydrophilic (polar) or hydrophobic (non-polar) polymers of high molecular weight and usually exhibit colloidal properties and can form gels or produce high viscosity dispersions or solutions at low concentrations with the use of suitable solvents. However, gum usually refers to plant or microbial polysaccharides or derivatives thereof that are dispersed in cold or hot water to form a viscous solution. Types include plant exudate gums, seaweed gums exuded from seaweed, seed gums exuded from plant seeds, starch and cellulose dervaties, microorganisms Microbial gums, and the like.

Commonly used gums include agar, carrageenan, and locust bean gum. Agar is a rubbery material derived from algae extracted from viscous complex polysaccharides, which are cell wall components of red algae, including Gelidium and Gracilaria . Agarose forms β-1,3 bonds of β-D-galactose and 3,6 anhydro-α-L-galactose, and agaropectin is a sulfated ester of galactose in the basic structure of agarose, or D-glucuronic acid and a small amount of pyrivic acid Is combined. That is, they belong to polyelectrolytes in structure. Agar is insoluble in cold water and is dissolved above 90 ° C to form colloidal solution. The properties of the agar are strong gelling, firm and form gels of brittle tissue, and do not dissolve well, ie have a high melting point.

Carrageenan was first extracted from Irish moss by residents of IRELAND Beach, County Carragheen, 600 years ago, and the term carrageen or carrageenan was first used in the patent literature on the separation and purification of irish moss from 1837 to 1871. Today, carrageenan is used in hundreds of products, from food to toothpaste, air fresheners and industrial suspensions. Carrageenan from red seaweed forms the basic structure of the galactan family of repeating units of β-D-galactose linked by β-1,3 bond and α-D-galactose linked by α-1,4 bond. have. Unlike the natural state, alkali treatment is required for commercial purposes, and there are differences in structural changes such as kappa-type, lota-type, and lambda-type depending on the alkali treatment. appear. Kappa carrageenan forms hard gels, lambda carrageenan does not form gels, and rotacarrageenan forms semi-gels similar to vanadium gelatin.

Locust bean gum is a polysaccharide derived from the seeds of perennial legumes (Ceratonia siliqua, carob tree, ever green tree), widely grown in Spain, Italy, Morocco, Turkey, and Portugal. The LBG powder may be ground or dissolved by dissolving in water, and after filtration, the polysaccharide thereof may be obtained by precipitation of alcohols. Its structure is galactosmannan {galactose 1 unit per 4 units of mannose}. Molecular weight of about 310,000 white or slightly yellowish brown powder, granular. It does not melt well in cold water, but melts well at about 80 ℃ and becomes mucus. The viscosity is well formed at Ph 3.5 ~ 9.0 and the viscosity is decreased by salt, magnesium, inorganic acid or oxidizing agent. When used in combination with carrageenan or xanthan gum, it forms an elastic gel.

The hydrogel composition used in cosmetics is used by mixing agar or carrageenan and logger beast gum, moisturizer, pH adjuster, metal ion sequestrant, etc. and gelating them with appropriate monovalent or divalent cations. Such a hydrogel composition exhibits a characteristic of adsorbing (absorbing) and releasing a large amount of solvents (solvents of water-soluble substances including water), that is, water release. Through Isu phenomenon, the beauty ingredients in the solvent bring the beauty effect of the skin.

However, the hydration of the hydrogel composition used in cosmetics is known to appear depending on the temperature of the skin (10 ~ 50 ℃) (Korea Patent Registration No. 10-506543) The hydrogel does not change to a fluid state by the temperature, Under the temperature of the hydrogel exposed to the air, the hydration occurs naturally. If the skin is closed under the temperature (10 ~ 50 ℃) (ie, about 2 ~ 10 times larger than the area of the hydrogel mask), the hydration phenomenon according to temperature does not continue. In addition, it is not yet known how the hydrogel composition according to the hydration effect on the moisturizing, elasticity of the skin.

SUMMARY OF THE INVENTION An object of the present invention for solving the above-mentioned conventional problems is that a hydrogel composition containing potassium alginate and potassium chloride, which are monovalent ions, in a hydrogel gel composition using a carrageenan and a locust bean gum, which are gelling polymers, are added in an appropriate combination Many phases appear, and the resulting moisturizing ingredients improve the adhesion of the skin as well as to provide a hydrogel composition that is effective in improving skin moisturizing, elasticity.

Therefore, this study intends to make a hydrogel that can control the elasticity, strength and completion of the hydrogel.

The elasticity and strength of the gel depends on the content and mixing ratio of the gums used. Especially, the hydrogels can be optimized for the degree of breakage, hardness, adhesion, and elasticity through mixed ionic bonds with monovalent cations. The technology seeks to develop products with optimized compatibility with suitable drug delivery materials.

Hydrogel composition for skin moisturizing and skin elasticity enhancement according to the characteristics of the present invention for solving the above problems, 0.5 to 3.0% by weight gelling polymer, 0.5 to 10.0% by weight collagen material, 5.0 to 20.0% by weight moisturizer, 0.04 ~ 1.0% by weight of monovalent cationic substance to adjust gel strength, 0.01 ~ 0.1% by weight of citric acid as acidity regulator, 0.02 ~ 0.1% by weight of metal ion sequestrant, 0.1 ~ 1.0% by weight of solubilizer (surfactant), combination It comprises 0.02-0.5% by weight fragrance, 0.2-0.6% preservative, and the remaining purified water.

Here, the hydrogel composition is moisturizing retention effect is made by adding 0.1 to 5% by weight of the nano-material containing any one of ceramide, hydrogenated lecithin, caprylic / capric triglyceride, T-Cocoyl glutamate or cholesterol It is preferable at the point of view.

Here, the gelling polymer is selected from the group consisting of agar, carrageenan, locust bean gum, gellan gum, the collagen material is marine collagen material extracted from fish dome scales, the moisturizing agent glycerin, butylene glycol, betaine, A substance selected from the group consisting of squalane, the monovalent cation material to control the gel strength is a material selected from the group consisting of potassium alginate, potassium chloride, the metal ion sequestrant is a disodium dithiate material, the solubilizing agent Is polysorbate, and the preservative may be composed of methylparaben and phenoxyethanol.

According to the above-described configuration of the present invention, the hydrogel composition of the present invention exhibits the best hydrate phenomenon, and thus has an excellent skin moisturizing effect.

In addition, the hydrogel composition can be maintained for a long time by adding particles in which nano-incorporated kinkin insoluble ceramide component is applied.

It is effective for skin beauty as a mask pack due to the bio-friendly characteristics of the excellent moisturizing effect as a cosmetic mask pack.

According to an embodiment of the present invention, it was found that the hydrogel did not have fluidity under temperature response at 35 ° C., which is due to the hydrolysis of the hydrogel.

Figure 1 is a graph showing the weight loss rate as a fraction of the completion phenomenon according to time and temperature using a hydrogel of Sample No. S1.

Figure 2 is a graph showing the weight loss rate as a fraction of the completion phenomenon according to time and temperature using a hydrogel of Sample No. S2.

FIG. 3 is a graph showing the weight loss rate as a fraction of the completion phenomenon according to time and temperature using a hydrogel of Sample No. S3.

Figure 4 is a graph showing the completion of the development according to time and temperature using the hydrogel of Sample No. S4 as the weight loss ratio as a fraction.

FIG. 5 is a graph showing the weight loss rate as a fraction of the completion phenomenon according to time and temperature using a hydrogel of Sample No. S5.

6 is a graph showing the weight loss rate as a fraction of the completion phenomenon according to time and temperature using a hydrogel of Sample No. S6.

Figure 7 is a graph measuring the moisturizing rate according to the hydrogel composition with time changes in a constant temperature and humidity conditions at 25 ℃.

Figure 8 is a graph measuring the moisturizing rate with time by adding 0.5%, 1%, 3%, 5% each of the cosmetic ingredients using nanotechnology to each hydrogel prescription.

9 is a graph showing the change in hardness according to the temperature of each hydrogel sample.

Hereinafter, with reference to the accompanying drawings will be described a hydrogel composition for enhancing skin moisturizing and skin elasticity and its effects according to the maturity characteristics according to the present invention.

The hydrogel composition according to the present invention can be used to prepare a mask pack containing a cosmetic ingredient incorporating nanotechnology in a cloth mesh.

Hydrogel composition according to the present invention, gelling polymer 0.5 ~ 3.0% by weight, collagen material 0.5 ~ 10.0% by weight, moisturizer 5.0 ~ 20.0% by weight, monovalent cationic substance to adjust the gel strength 0.04-1.0% by weight, acidity regulator 0.01 ~ 0.1%, 0.02 ~ 0.1% by weight of metal ion blocker, 0.1 ~ 1.0% by weight of solubilizer (surfactant), 0.02 ~ 0.5% by weight of combination fragrance, 0.2 ~ 0.6% of preservative, 58.7 ~ 93.51% by weight of purified water One nanomaterial may comprise 0.1-5%.

More specifically, the hydrogel composition according to the present invention is 0.5wt% to 3.0wt% of a substance selected from the group consisting of gelling polymers agar, carrageenan, locust bean gum and gellan gum, and marine collagen material extracted from fish dome scales 0.5 to 10.0. Weight%, moisturizing agents selected from the group consisting of glycerin, butylene glycol, betaine, squalane 5.0wt% to 20.0wt%, a monovalent cationic substance for controlling the gel strength potassium alginate, potassium chloride selected from the group consisting of 0.04 ~ 1.0% by weight of material, 0.01 ~ 0.1% by weight of citrate acid as acidity regulator, 0.02 ~ 0.1% by weight of disodium IDT, which is a metal ion sequestering agent, 0.1 ~ 1.0% by weight, which is 20 solubilizing agent of polysorbate 20, Combination fragrance substance 0.02 ~ 0.5% by weight, preservatives methylparaben, phenoxyethanol substance 0.2 ~ 0.6% by weight, nanomaterials ceramide, hydrogenated lecithin, caprylic / capric tree Lee triglyceride, tea yieyi-cocoyl glutamate, nanomaterials consisting of cholesterol, 0.1 may be formed, including 5.0% by weight purified water 58.7 - 93.51% by weight.

The content of the gum agar, carrageenan, logger bean bean gum, gellan gum and the like is preferably 0.5wt to 3wt% based on the total weight of the composition.

This is because the hardness of the gel does not appear when the content is less than 0.5wt% on the basis of the total blending content, because the hardness of the gel is too high when the content is more than 3wt%, the commercial value is lowered.

In the case of the moisturizing glycerin, butylene glycol, betaine, squalane, the content is preferably 5wt% to 20wt% based on the total weight of the composition.

This may cause the gel mask to fall easily when attached to the face when the content is less than 5 wt% based on the total blending amount, that is, when the content is 20 wt% or more, it may cause stickiness to the face after using the gel mask. Therefore, 5% to 20% of the content is appropriate to give skin moisturization without adhesion and stickiness of the hydrogel.

Ceramide, hydrogenated lecithin, caprylic / capric triglyceride, tie-cocoyl glutamate, and cholesterol components used as nanoderivatives and cosmetic ingredients, which can make nanoparticles using high pressure Three rotations were carried out using a Midroflurdizer) instrument to produce nanoparticles with emulsion particles of 70 nm to 300 nm. Nanoemulsion particles are typically used under 150 nm to 300 nm.

In the case of the hydrogel composition, glycerin and butylene glycol, which are used moisturizers, can easily maintain the moisturizing power according to the change over time after using the hydrogel mask.

Therefore, when the hydrogel was used with 0.1% to 5wt% of nanomaterial granulated with ceramide having a skin barrier function, it was found that the moisture retention was significantly maintained as compared with the case of using a general moisturizer. Can be.

A substance selected from the group consisting of 0.02 wt% to 0.1 wt% of chelating agent, 0.1 wt% to 0.5 wt% of cellulose gum which is a gelling polymer, potassium alginate as monovalent cationic material, potassium chloride, and citric acid as acidity regulator 0.01wt% to 0.1wt% affects the stability of the product and the hardness of the product, it can be seen that it has a great effect on the completion of hydrogel composition according to the appropriate cross-linking.

0.2wt% to 0.6wt% in the group consisting of methylparaben and phenoxyethanol as preservatives, 0.05wt% as polysorbate 20 as a solubilizer, and 0.02wt% to 0.1wt% as a combination fragrance for external contamination by microorganisms of the hydrogel composition It prevents from and improves product quality.

The hydrogel composition according to the present invention may be appropriately mixed and administered in an appropriate amount in consideration of the required action, that is, diarrhea and moisturizing effect.

In addition, the composition according to the present invention may further include a drug delivery material using other nanotechnology generally known.

Typical drug delivery agents that may be used include ceramides, phytosphingosines, oil-soluble cosmetics, and the like, such as tocopherol acetate, retinol, and the like, as well as bases, excipients, lubricants, and preservatives.

EXAMPLE

Samples of the hydrogel composition were prepared according to the preparation method of combining the six samples shown in the following [Table 1] with the following components.

Table 1

No.	Phase	Trade Name	Sample.No
			S1	S2	S3	S4	S5	S6
One	A	Agar	One	0	0	0	0	0
2		Carrageenan	1.000	1.000	1.000	1.000	1.000	1.000
3		Locust Bean Sword	1.000	1.000	1.000	1.000	1.000	1.000
4		glycerin	12.00	12.00	12.00	12.00	12.00	12.00
5	B	Disodium ID	0.10	0.10	0.10	0.10	0.10	0.10
6		Methylparaben	0.15	0.15	0.15	0.15	0.15	0.15
7		Betaine	0.01	0.01	0.01	0.01	0.01	0.01
8		Purified water	76.37	77.37	77.29	77.28	77.20	77.33
9	C	Butylene Glycol	7.00	7.00	7.00	7.00	7.00	7.00
10		Cellulose gum	0.20	0.20	0.20	0.20	0.20	0.20
11	D	Potassium alginate	0.00	0.00	0.08		0.08	0.00
12		Potassium chloride	0.00	0.00		0.09	0.09	0.00
13		Citric Acid						0.04
14	E	Phenoxyethanol	0.1	0.1	0.1	0.1	0.1	0.1
15		Squalane	0.01	0.01	0.01	0.01	0.01	0.01
16		Marine collagen	One	One	One	One	One	One
17		Polysorbate 20	0.05	0.05	0.05	0.05	0.05	0.05
18	F	incense	0.01	0.01	0.01	0.01	0.01	0.01
			to 100	to 100	to 100	to 100	to 100	to 100

Hydrogel composition was made using a total of six prescriptions from Sample.No.S1 to Sample.No.S6 as shown in Table 1 of the Examples.

In the hydrogel composition, the A and B phases are sequentially added to the HOMO mixer kiln, stirred from room temperature, gradually stirred at about 80 ° C, the temperature is raised, and sufficiently stirred and dispersed.

After sufficiently confirming the dispersion, the phase C was stirred at room temperature, and then charged into a mixer kiln, followed by gradual stirring to disperse.

After sufficiently confirming the dispersion, phase D is added to a mixer kiln and slowly stirred to dissolve.

After confirming the dissolution, the E and F phases are sequentially added and stirred. After stirring for about 5 to 10 minutes using a coating machine to make a hydrogel using a PET material or OPP material and a mesh type mesh cloth used as a support for the hydrogel to make a gelled mask by cooling to about 30 ℃.

[Feature Characteristics Analysis]

The gelled hydrogel mask of the six samples described above was reduced to make samples corresponding to 4 ° C, 25 ° C, 35 ° C and 50 ° C. At this time, each sample is classified into an A-type in which the hydrogel is sealed and a B-type in the open state.

Figures 1 to 6 are graphs showing the weight loss rate as a fraction of the completion of development according to time and temperature using the hydrogels of Sample No. S1 to Sample No. S6. Here, Sample.No.S1 / A to Sample.No.S6 / A are in a sealed state, and Sample.No.S1 / B to Sample.No.S6 / B mean an open state.

Samples were prepared for each temperature, and the completion phenomenon over time was measured by weight. The measured values are shown in FIGS. 1 to 6 in terms of percentages.

Analysis of the hydrogel hydration according to the prescription of Figures 1 to 6, in the case of Sample.No.S1 based on agar, which is a gum, using the remaining carrageenan and locust bean gum. The weight change rate was higher due to the completion of S6.

Looking at the completion of hydrogel according to the prescription of Figures 1 to 6, the completion of the phenomenon in both the sealed state and the opened state of the hydrogel, but the completion of the phenomenon in the opened state compared to the sealed state, As the temperature rose, the process was relatively larger.

In addition, in the case of the sealed state in all of Figures 1 to 5 in 4 ℃ ~ 35 ℃ the degree of completion of the hydrogel in the sealed state was found to be around 5% on average, Figure 1 to Figure 4 (Sample under 50 ℃) In No. S1 to S4, the completion phenomenon appeared within 5% to 6%, and in FIG. 6 (Sample.No.S6), the completion phenomenon appeared to 20 wt%.

Analyzing the experimental values shown on these graphs, it can be seen that in the case of Sample.No.S1 to S5 (FIGS. 1 to 5) at 35 ° C., the completion phenomenon in the sealed state and the unsealed state varies with time. Compared to this, Sample.No. In the case of S6 (FIG. 6), it can be seen that the hydrolysis of the hydrogel mask in the sealed state and the unsealed state under 35 ° C. is lowered equally.

In other words, the analysis of the completion of the six hydrogel composition according to the formulation of Figures 1 to 6 as a result of the analysis showed that the completion of the carbo nan sample.No.S2 ~ S6 using agar than the sample.No.S1 using agar. In addition, it can be seen that the completion of the prescription of Sample.No.S6 containing citric acid was larger than that of Sample.No.S3 to S5 containing monovalent cations.

[Moisture Analysis of Hydrogels]

Moisturizing power was analyzed using Corneometer (CM820PC, Courage Khazka, Germany) at 25 ° C. under room constant temperature and humidity conditions.

As shown in FIG. 7, hydrogel masks were prepared according to the prescription of Sample. No. S1 to S6, and then applied to the face and removed after 1 hour, and the change in moisturizing power over time was measured.

In the case of the hydrogel composition as shown in Figure 7, it was found that the measured value of the moisturizing force immediately after use of the hydrogel was lowered after 30 minutes.

It can be seen that the relatively high moisturizing power of the hydrogel of the sample No. S6 prescription is relatively high. It was found that when the ingredients such as glycerin, butylene glycol, and betaine used as moisturizers were sufficiently applied to the face, it retained a certain amount of moisturizing power. Correlated with the case of hydrogels.

These experiments show that the hydrogel is well correlated with the moisturizing properties of the skin.

However, it can be seen that the moisturizing effect of the moisturizer used in the hydrogel is significantly reduced after 30 minutes.

[Moisture Analysis of Hydrogel Using Nano Technology]

Figure 8 is a graph measuring the moisturizing rate with time by adding 0.5%, 1%, 3%, 5% each of the cosmetic ingredients using nanotechnology to each hydrogel prescription.

Ceramide, hydrogenated lecithin, caprylic / capric triglyceride, tie-cocoyl glutamate, and cholesterol components used as nanoderivatives and cosmetic ingredients are appropriately mixed to make nanoparticles using high pressure, and then 0.5wt% to 5wt% The hydrogel mask was prepared by adding to the prescription of Sample.No.S6, and then the moisturizing power of the hydrogel mask was measured at 25 ° C. under constant temperature and humidity conditions.

Sample.No.S6 (0.0wt%) has 0.0wt% of nanomaterial added to Sample.No.S6, Sample.No.S6 (0.5wt%) has 0.5wt% of nanomaterial added to Sample.No.S6, Sample.No.S6 (1.0wt%) has 1.0wt% of nanomaterial added to Sample.No.S6, Sample.No.S6 (3.0wt%) has 3.0wt% of nanomaterial added to Sample.No.S6, Sample No. S6 (5.0 wt%) means that the nanomaterial addition rate is 5.0 wt% in Sample No. S 6.

Moisturizing power was measured after each of the nano-ceramic components were contained according to the composition ratio, and the results showed that the moisturizing power was more sustained in the remaining samples containing nano ceramide than Sample.No.S6 (0.0 wt%) without the nano ceramide. give.

However, it can be seen that the moisturizing retention effect according to the content of the nanomaterials 0.5wt%, 1wt%, 3wt%, 5wt% is not significantly different.

It is thought that ceramide with skin barrier function penetrates the skin according to hydration and relatively strengthens skin barrier function. Caprylic / capric triglycerides and cholesterol components, which are oil components contained in nano components, It is effective in maintaining moisturizing.

Hydrogel Hardness Analysis

9 is a graph showing the change in hardness according to the temperature of each hydrogel sample.

The hardness value according to the temperature of the contents according to the formulation of each hydrogel composition was measured.

The hardness measuring device was a FUDOH RHEOMETER. (Japan JAPAN), the plunger area (PLUNGER AREA) is 1cm2, the lift up speed (lift up speed) was measured the hardness of the hydrogel under 6cm / min.

Experimental conditions were made after the preparation of the hydrogel according to the prescription and the hydrogel contents according to the sealed state and the unsealed state in the same conditions as in Experimental Example 1 into the incubater for each temperature and measured after 30 minutes. Table 10 shows the change in hardness of the hydrogel composition with temperature.

In the case of FIG. 9, the hardness change according to the temperature of the sealed hydrogel and the unsealed hydrogel shows a different tendency as a result of measuring the change in hardness.

In the case of closed hydrogels, the change in hardness value tends to decrease little by little depending on the temperature, but the difference in change is not large. It can be seen that the change in hardness value significantly increases with the temperature of 50 ℃.

The experimental results did not find statistical significance in the correlation between the hydrogel completion and hardness values, but in the case of open hydrogels, the hardness value increased. It can be seen that this phenomenon is caused by the surface of the hydrogel is dried according to the phenomenon.

Although the preferred embodiments of the present invention have been described above with reference to the accompanying drawings, the above-described technical configuration of the present invention may be embodied by those skilled in the art to which the present invention pertains without changing its technical spirit or essential features of the present invention. It will be appreciated that the present invention may be practiced as. Therefore, the above-described embodiments are to be understood as illustrative and not restrictive in all respects, and the scope of the present invention is indicated by the appended claims rather than the detailed description, and the meaning and scope of the claims and All changes or modifications derived from the equivalent concept should be interpreted as being included in the scope of the present invention.

Claims (3)

1. 0.5 to 3.0% by weight of gelling polymer, 0.5 to 10.0% by weight of collagen material, 5.0 to 20.0% by weight of moisturizer, 0.04 to 1.0% by weight of monovalent cationic substance to adjust gel strength, 0.01 to 0.1% by weight of citric acid, an acidity regulator, Skin moisturizing according to the mucous characteristics, including 0.02 to 0.1% by weight of metal ion blocker, 0.1 to 1.0% by weight of solubilizer (surfactant), 0.02 to 0.5% by weight of combination fragrance, 0.2 to 0.6% of preservative, and the remaining purified water Hydrogel composition for enhancing skin elasticity.
2. The method of claim 1,

   The hydrogel composition comprises 0.1-5% by weight of nanomaterials containing any one of ceramide, hydrogenated lecithin, caprylic / capric triglyceride, TY-cocoil glutamate, or cholesterol, according to the skin characteristics. Hydrogel composition for moisturizing and enhancing skin elasticity.
3. The method of claim 1,

   The gelling polymer is selected from the group consisting of agar, carrageenan, rogast bean gum, gellan gum,

   The collagen material is marine collagen material extracted from fish dome scales,

   The moisturizing agent is a material selected from the group consisting of glycerin, butylene glycol, betaine, squalane,

   The monovalent cation material for controlling the gel strength is a material selected from the group consisting of potassium alginate, potassium chloride,

   The metal ion sequestrant is a disodium id material,

   The solubilizer is polysorbate,

   The preservative is made of methyl paraben and phenoxy ethanol, hydrogel composition for enhancing skin moisturizing and skin elasticity according to diuretic properties.

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