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WO2010079209A3 - Compositions for treating wounds and skin conditions - Google Patents

Compositions for treating wounds and skin conditions Download PDF

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Publication number
WO2010079209A3
WO2010079209A3 PCT/EP2010/050141 EP2010050141W WO2010079209A3 WO 2010079209 A3 WO2010079209 A3 WO 2010079209A3 EP 2010050141 W EP2010050141 W EP 2010050141W WO 2010079209 A3 WO2010079209 A3 WO 2010079209A3
Authority
WO
WIPO (PCT)
Prior art keywords
composition
skin
skin conditions
compositions
treating
Prior art date
Application number
PCT/EP2010/050141
Other languages
French (fr)
Other versions
WO2010079209A2 (en
Inventor
Alexandr A. Golub
Olga Biliaieva
Viacheslav V. Neshta
Frank Sams-Dodd
Original Assignee
Golub Alexandr A
Olga Biliaieva
Neshta Viacheslav V
Frank Sams-Dodd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Golub Alexandr A, Olga Biliaieva, Neshta Viacheslav V, Frank Sams-Dodd filed Critical Golub Alexandr A
Publication of WO2010079209A2 publication Critical patent/WO2010079209A2/en
Publication of WO2010079209A3 publication Critical patent/WO2010079209A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/18—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing inorganic materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/38—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing enzymes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/42—Use of materials characterised by their function or physical properties
    • A61L15/44—Medicaments
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/42—Use of materials characterised by their function or physical properties
    • A61L15/46—Deodorants or malodour counteractants, e.g. to inhibit the formation of ammonia or bacteria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
    • A61L26/0004—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form containing inorganic materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
    • A61L26/0009—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form containing macromolecular materials
    • A61L26/0019—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form containing macromolecular materials obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
    • A61L26/0009—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form containing macromolecular materials
    • A61L26/0028—Polypeptides; Proteins; Degradation products thereof
    • A61L26/0047—Specific proteins or polypeptides not covered by groups A61L26/0033 - A61L26/0042
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
    • A61L26/0061—Use of materials characterised by their function or physical properties
    • A61L26/0066—Medicaments; Biocides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/20—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
    • A61L2300/252—Polypeptides, proteins, e.g. glycoproteins, lipoproteins, cytokines
    • A61L2300/254—Enzymes, proenzymes

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Materials Engineering (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Hematology (AREA)
  • Inorganic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)

Abstract

The invention is the composition and the use of the composition substantially consisting of a siliceous sorbent and a medicinal agent immobilized thereon, wherein the siliceous sorbent is aerosil and the medicinal agent is serrathiopeptidase, and where the composition may be used to particular advantage for treating and promoting the healing of acute and chronic, open and closed wounds, burns, skin infections, for reducing bleeding, for wound cleansing, for removal of necrotic tissue, for reducing scar-formation, for treating skin conditions, and for cosmetic skin cleansing by applying the composition to the wound, the tissue or the skin.
PCT/EP2010/050141 2009-01-08 2010-01-08 Compositions for treating wounds and skin conditions WO2010079209A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US14317809P 2009-01-08 2009-01-08
US61/143,178 2009-01-08

Publications (2)

Publication Number Publication Date
WO2010079209A2 WO2010079209A2 (en) 2010-07-15
WO2010079209A3 true WO2010079209A3 (en) 2010-09-02

Family

ID=42078341

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2010/050141 WO2010079209A2 (en) 2009-01-08 2010-01-08 Compositions for treating wounds and skin conditions

Country Status (1)

Country Link
WO (1) WO2010079209A2 (en)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
UA66800U (en) * 2011-02-08 2012-01-25 Ольга Александровна Беляева LINESIL, complex sorption-probiotic preparation for treatment of purulent wounds
MX2013013219A (en) 2011-05-12 2014-07-28 Smith & Nephew Orthopaedics Ag Wound debridement compositions containing seaprose and methods of wound treatment using same.
MX2014013745A (en) * 2012-05-11 2016-05-05 Smith & Nephew Inc Use of seaprose to remove bacterial biofilm.
WO2014067933A1 (en) * 2012-10-31 2014-05-08 C-Lecta Gmbh Bioactive carrier preparation for enhanced safety in care products and food
WO2016071405A2 (en) * 2014-11-04 2016-05-12 Invenres Gmbh Pharmaceutical preparation and method of its production and use
US10226425B2 (en) * 2013-11-06 2019-03-12 Invenres Gmbh Pharmaceutical preparation and method of its production and use
WO2015116529A2 (en) 2014-01-31 2015-08-06 Sorption Therapeutics, Llc Methods and compositions for treating skin
LT6177B (en) 2014-10-10 2015-07-27 Uab "Biocentras" ISOLATION OF ENZYME COMPLEXES FROM Streptomyces gougerotii 101, PREPARATION AND APPLICATION OF MULTIENZYME BIOPREPARATIONS
JP7127013B2 (en) 2016-07-27 2022-08-29 スミス アンド ネフュー インコーポレイテッド Use of Thermolysin to Reduce or Remove Bacterial Biofilms from Surfaces
CN106693075A (en) * 2016-11-28 2017-05-24 深圳齐康医疗器械有限公司 Antibacterial artificial dermal scaffold and preparation method of antibacterial artificial dermal scaffold
US11413300B2 (en) 2017-01-30 2022-08-16 Smith & Nephew, Inc. Synergistic combination of thermolysin and an antibacterial agent to reduce or eliminate bacterial biofilms from surfaces
CN108309941B (en) * 2018-03-20 2023-08-11 南京工业大学 Serratase external powder and preparation method thereof
CN116407611A (en) * 2021-12-29 2023-07-11 四川好医生攀西药业有限责任公司 Application of polypeptide in preparation of products for preventing or treating skin injury diseases

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3792160A (en) * 1972-01-18 1974-02-12 Takeda Chemical Industries Ltd Method of treating inflammation and composition therefor
EP0072947A2 (en) * 1981-08-10 1983-03-02 Kaken Pharmaceutical Co., Ltd. Agent for the prevention and treatment of liver diseases
UA65716A (en) * 2003-03-03 2004-04-15 Olha Oleksandrivna Biliaieva Complex antibacterial sorption composition "benegol forte" for preventing anaerobic infection and treating purulent wounds, neurepathic eschar, and burns, method for its manufacture and application
US20040234474A1 (en) * 2001-07-24 2004-11-25 Alvin Berlat Topical pharmaceutical formulation
UA28103U (en) * 2007-07-12 2007-11-26 Ольга Олександрівна Біляєва Complex antibacterial sorption composition possessing necrolytic effect for treating purulent wounds, trophic ulcers, and wounds

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3792160A (en) * 1972-01-18 1974-02-12 Takeda Chemical Industries Ltd Method of treating inflammation and composition therefor
EP0072947A2 (en) * 1981-08-10 1983-03-02 Kaken Pharmaceutical Co., Ltd. Agent for the prevention and treatment of liver diseases
US20040234474A1 (en) * 2001-07-24 2004-11-25 Alvin Berlat Topical pharmaceutical formulation
UA65716A (en) * 2003-03-03 2004-04-15 Olha Oleksandrivna Biliaieva Complex antibacterial sorption composition "benegol forte" for preventing anaerobic infection and treating purulent wounds, neurepathic eschar, and burns, method for its manufacture and application
UA28103U (en) * 2007-07-12 2007-11-26 Ольга Олександрівна Біляєва Complex antibacterial sorption composition possessing necrolytic effect for treating purulent wounds, trophic ulcers, and wounds
WO2009008851A2 (en) * 2007-07-12 2009-01-15 Golub Alexandr A Antimicrobial composition

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
L. SELAN ET AL.: "PROTEOLYTIC ENZYMES: A NEW TREATMENT STRATEGY FOR PROSTHETIC INFECTIONS?", ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, vol. 37, no. 12, December 1993 (1993-12-01), pages 2618 - 2621, XP002587470 *
MAHESHWARI M ET AL: "DEVELOPMENT OF TETRACYCLINE-SERRATIOPEPTIDASE-CONTAINING PERIODONTAL GEL: FORMULATION AND PRELIMINARY CLINICAL STUDY", AAPS PHARMSCITECH, SPRINGER NEW YORK LLC, US LNKD- DOI:10.1208/PT070376, vol. 7, no. 3, 1 January 2006 (2006-01-01), pages E1 - E10, XP002547740, ISSN: 1530-9932, [retrieved on 20060915] *
MAZZONE A ET AL: "Evaluation of Serratia peptidase in acute or chronic inflammation of otorhinolaryngology pathology: a multicentre, double-blind, randomized trialversus placebo", JOURNAL OF INTERNATIONAL MEDICAL RESEARCH, CAMBRIDGE MEDICAL PUBLICATIONS LTD, GB, vol. 18, no. 5, 1 September 1990 (1990-09-01), pages 379 - 388, XP008089114, ISSN: 0300-0605 *

Also Published As

Publication number Publication date
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