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WO2007029082A3 - An improved fermentation process for preparing ascomycin - Google Patents

An improved fermentation process for preparing ascomycin Download PDF

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Publication number
WO2007029082A3
WO2007029082A3 PCT/IB2006/002409 IB2006002409W WO2007029082A3 WO 2007029082 A3 WO2007029082 A3 WO 2007029082A3 IB 2006002409 W IB2006002409 W IB 2006002409W WO 2007029082 A3 WO2007029082 A3 WO 2007029082A3
Authority
WO
WIPO (PCT)
Prior art keywords
ascomycin
fermentation process
preparing
improved fermentation
improved
Prior art date
Application number
PCT/IB2006/002409
Other languages
French (fr)
Other versions
WO2007029082A2 (en
Inventor
Parveen Kumar
Sanjeev Kumar Sharma
Hitesh Kumar Malviya
Ramanchandran Balasubramanian
Ashubhai Dalal
Original Assignee
Ranbaxy Lab Ltd
Parveen Kumar
Sanjeev Kumar Sharma
Hitesh Kumar Malviya
Ramanchandran Balasubramanian
Ashubhai Dalal
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ranbaxy Lab Ltd, Parveen Kumar, Sanjeev Kumar Sharma, Hitesh Kumar Malviya, Ramanchandran Balasubramanian, Ashubhai Dalal filed Critical Ranbaxy Lab Ltd
Publication of WO2007029082A2 publication Critical patent/WO2007029082A2/en
Publication of WO2007029082A3 publication Critical patent/WO2007029082A3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
    • C07D498/18—Bridged systems
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/18—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms containing at least two hetero rings condensed among themselves or condensed with a common carbocyclic ring system, e.g. rifamycin
    • C12P17/188—Heterocyclic compound containing in the condensed system at least one hetero ring having nitrogen atoms and oxygen atoms as the only ring heteroatoms

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

The present invention relates to an improved fermentation process for the preparation of ascomycin.
PCT/IB2006/002409 2005-09-05 2006-09-01 An improved fermentation process for preparing ascomycin WO2007029082A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN2363/DEL/2005 2005-09-05
IN2363DE2005 2005-09-05

Publications (2)

Publication Number Publication Date
WO2007029082A2 WO2007029082A2 (en) 2007-03-15
WO2007029082A3 true WO2007029082A3 (en) 2007-04-26

Family

ID=37714237

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IB2006/002409 WO2007029082A2 (en) 2005-09-05 2006-09-01 An improved fermentation process for preparing ascomycin

Country Status (1)

Country Link
WO (1) WO2007029082A2 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107245460A (en) * 2017-05-18 2017-10-13 福建省微生物研究所 Streptomyces hygroscopicus mutant strain for high yield of ascomycin and application thereof

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5339823B2 (en) 2008-09-02 2013-11-13 公益財団法人微生物化学研究会 Novel compound ceramidastine, its production method and its use

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3244592A (en) * 1962-06-09 1966-04-05 Arai Tadashi Ascomycin and process for its production
EP0184162A2 (en) * 1984-12-03 1986-06-11 Fujisawa Pharmaceutical Co., Ltd. Tricyclo compounds, a process for their production and a pharmaceutical composition containing the same

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3244592A (en) * 1962-06-09 1966-04-05 Arai Tadashi Ascomycin and process for its production
EP0184162A2 (en) * 1984-12-03 1986-06-11 Fujisawa Pharmaceutical Co., Ltd. Tricyclo compounds, a process for their production and a pharmaceutical composition containing the same

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
HATANAKA H ET AL: "FR-900520 AND FR-900523, NOVEL IMMUNOSUPPRESSANTS ISOLATED FROM A STREPTOMYCES II. FERMENTATION, ISOLATION AND PHYSICO-CHEMICAL AND BIOLOGICAL CHARACTERISTICS", JOURNAL OF ANTIBIOTICS, JAPAN ANTIBIOTICS RESEARCH ASSOCIATION, TOKYO, JP, vol. 41, no. 11, November 1988 (1988-11-01), pages 1592 - 1601, XP009064959, ISSN: 0021-8820 *
JUNKER B ET AL: "Secondary metabolite scale-up to minimize homolog impurity levels", BIOTECHNOLOGY AND BIOENGINEERING, INTERSCIENCE PUBLISHERS, LONDON, GB, vol. 59, no. 5, 1998, pages 595 - 604, XP002175770, ISSN: 0006-3592 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107245460A (en) * 2017-05-18 2017-10-13 福建省微生物研究所 Streptomyces hygroscopicus mutant strain for high yield of ascomycin and application thereof

Also Published As

Publication number Publication date
WO2007029082A2 (en) 2007-03-15

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