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WO2007054970A3 - Novel polymorphic forms of (s)-(-)-2-amino-6-(n- propylamino) 4,5,6,7- tetrahydrobenzothiazole - Google Patents

Novel polymorphic forms of (s)-(-)-2-amino-6-(n- propylamino) 4,5,6,7- tetrahydrobenzothiazole Download PDF

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Publication number
WO2007054970A3
WO2007054970A3 PCT/IN2006/000377 IN2006000377W WO2007054970A3 WO 2007054970 A3 WO2007054970 A3 WO 2007054970A3 IN 2006000377 W IN2006000377 W IN 2006000377W WO 2007054970 A3 WO2007054970 A3 WO 2007054970A3
Authority
WO
WIPO (PCT)
Prior art keywords
tetrahydrobenzothiazole
propylamino
amino
polymorphic forms
novel polymorphic
Prior art date
Application number
PCT/IN2006/000377
Other languages
French (fr)
Other versions
WO2007054970A2 (en
Inventor
Pandurang Balwant Deshpande
Anand Kumar Pandey
Sanjay Lakhabha Vasoya
Piyush Mansukhbhai Vaghasia
Kamlesh Sanmukhbhai Soni
Original Assignee
Alembic Ltd
Pandurang Balwant Deshpande
Anand Kumar Pandey
Sanjay Lakhabha Vasoya
Piyush Mansukhbhai Vaghasia
Kamlesh Sanmukhbhai Soni
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alembic Ltd, Pandurang Balwant Deshpande, Anand Kumar Pandey, Sanjay Lakhabha Vasoya, Piyush Mansukhbhai Vaghasia, Kamlesh Sanmukhbhai Soni filed Critical Alembic Ltd
Publication of WO2007054970A2 publication Critical patent/WO2007054970A2/en
Publication of WO2007054970A3 publication Critical patent/WO2007054970A3/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
    • C07D277/62—Benzothiazoles
    • C07D277/68—Benzothiazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C07D277/82—Nitrogen atoms

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

The present invention relates to novel polymorphic forms of (S)-(-)-2-Amino-6-(n- propylamino)-4,5,6,7-tetrahydrobenzothiazole designated as Form I, II, III and IV and its process for preparation.
PCT/IN2006/000377 2005-10-25 2006-09-14 Novel polymorphic forms of (s)-(-)-2-amino-6-(n- propylamino) 4,5,6,7- tetrahydrobenzothiazole WO2007054970A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN1344MU2005 2005-10-25
IN1344/MUM/2005 2005-10-25

Publications (2)

Publication Number Publication Date
WO2007054970A2 WO2007054970A2 (en) 2007-05-18
WO2007054970A3 true WO2007054970A3 (en) 2007-12-06

Family

ID=38023683

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IN2006/000377 WO2007054970A2 (en) 2005-10-25 2006-09-14 Novel polymorphic forms of (s)-(-)-2-amino-6-(n- propylamino) 4,5,6,7- tetrahydrobenzothiazole

Country Status (1)

Country Link
WO (1) WO2007054970A2 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107540634A (en) * 2016-06-27 2018-01-05 江苏神龙药业股份有限公司 A kind of novel crystal forms of Pramipexole Monohydrochloride and preparation method thereof
CN107540632A (en) * 2016-06-27 2018-01-05 江苏神龙药业股份有限公司 A kind of novel crystal forms of Pramipexole Monohydrochloride and preparation method thereof
CN115073391B (en) * 2022-07-26 2023-04-07 山东京卫制药有限公司 Novel crystal form of pramipexole triphenacetate and preparation method thereof
CN115141161B (en) * 2022-07-26 2023-03-28 山东京卫制药有限公司 Crystal form A of pramipexole xinafoate and preparation method thereof

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002022591A1 (en) * 2000-09-18 2002-03-21 Synthon B.V. Process for resolution of 2-amino-6-propylamino-4,5,6,7-tetrahydrobenzothiazole and compounds therefor
WO2006117614A1 (en) * 2005-05-03 2006-11-09 Ranbaxy Laboratories Limited Process for the preparation of pramipexole and new anhydrous forms of its dihydrochloride

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002022591A1 (en) * 2000-09-18 2002-03-21 Synthon B.V. Process for resolution of 2-amino-6-propylamino-4,5,6,7-tetrahydrobenzothiazole and compounds therefor
WO2006117614A1 (en) * 2005-05-03 2006-11-09 Ranbaxy Laboratories Limited Process for the preparation of pramipexole and new anhydrous forms of its dihydrochloride

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
SCHNEIDER, C. S. ET AL.: "Dopamine autoreceptor agonists: resolution and pharmacological activity of 2,6-diaminotetrahydrobenzothiazole and aminothiazole analogue of apomorphine", JOURNAL OF MEDICINAL CHEMISTRY, AMERICAN CHEMICAL SOCIETY. WASHINGTON, US, vol. 30, no. 3, March 1987 (1987-03-01), pages 494 - 498, XP002186199, ISSN: 0022-2623 *

Also Published As

Publication number Publication date
WO2007054970A2 (en) 2007-05-18

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