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WO2007051139A2 - Systemes et procedes de gestion du diabete - Google Patents

Systemes et procedes de gestion du diabete Download PDF

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Publication number
WO2007051139A2
WO2007051139A2 PCT/US2006/060260 US2006060260W WO2007051139A2 WO 2007051139 A2 WO2007051139 A2 WO 2007051139A2 US 2006060260 W US2006060260 W US 2006060260W WO 2007051139 A2 WO2007051139 A2 WO 2007051139A2
Authority
WO
WIPO (PCT)
Prior art keywords
user
delivery device
sensor data
sensor assembly
sensor
Prior art date
Application number
PCT/US2006/060260
Other languages
English (en)
Other versions
WO2007051139A3 (fr
Inventor
Luis Malave
John Garibotto
Jefferey Smith
Robert Campbell
Original Assignee
Insulet Corporation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Insulet Corporation filed Critical Insulet Corporation
Publication of WO2007051139A2 publication Critical patent/WO2007051139A2/fr
Publication of WO2007051139A3 publication Critical patent/WO2007051139A3/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142—Pressure infusion, e.g. using pumps
    • A61M5/14244—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0002—Remote monitoring of patients using telemetry, e.g. transmission of vital signals via a communication network
    • A61B5/0031—Implanted circuitry
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/14532—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue for measuring glucose, e.g. by tissue impedance measurement
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/168—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body
    • A61M5/172—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body electrical or electronic
    • A61M5/1723—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body electrical or electronic using feedback of body parameters, e.g. blood-sugar, pressure
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H20/00—ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance
    • G16H20/10—ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to drugs or medications, e.g. for ensuring correct administration to patients
    • G16H20/17—ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to drugs or medications, e.g. for ensuring correct administration to patients delivered via infusion or injection
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H40/00—ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices
    • G16H40/60—ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices
    • G16H40/67—ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices for remote operation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142—Pressure infusion, e.g. using pumps
    • A61M2005/14208—Pressure infusion, e.g. using pumps with a programmable infusion control system, characterised by the infusion program
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/35—Communication
    • A61M2205/3546—Range
    • A61M2205/3569—Range sublocal, e.g. between console and disposable
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/35—Communication
    • A61M2205/3576—Communication with non implanted data transmission devices, e.g. using external transmitter or receiver
    • A61M2205/3592—Communication with non implanted data transmission devices, e.g. using external transmitter or receiver using telemetric means, e.g. radio or optical transmission
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/50—General characteristics of the apparatus with microprocessors or computers
    • A61M2205/52—General characteristics of the apparatus with microprocessors or computers with memories providing a history of measured variating parameters of apparatus or patient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2209/00—Ancillary equipment
    • A61M2209/01—Remote controllers for specific apparatus

Definitions

  • This invention relates to medical devices / systems and, more particularly, to medical devices / system having a drug delivery portion, a physiological condition sensor portion and a remote control portion wherein one or more of said systems communicate with one another wirelessly.
  • a wide variety of ambulatory infusion devices / pumps have been developed to deliver liquid medicaments to patients for the treatment of various diseases. Depending upon the disease and the corresponding medication it may be useful to obtain feedback from the patient during the course treatment and use such feedback to modify the treatment regimen.
  • CSII continuous subcutaneous insulin infusion
  • glucose measurement methods are known and/or are being developed, including a variety of blood glucose test strips and strip readers and, more recently, implanted continuous glucose sensors, subcutaneous interstitial fluid glucose sensors, non-invasive sensors and others.
  • Many insulin delivery systems and glucose measurement systems are not well integrated with one another.
  • One example of an integrated insulin delivery system and strip/strip reader system is described in U.S. Pat. App. No. 10/827582.
  • Some systems that integrate insulin delivery systems with continuous or discrete, high frequency glucose sensing have also been proposed.
  • such proposed systems suffer from various disadvantages.
  • some such systems require additional system components to coordinate the glucose data and the insulin delivery.
  • some systems require that the patient be electronically tethered to a device that is dedicated to receiving and storing the continuous or discrete high frequency glucose data. In such systems, the user must stay in close proximity to a such a sensor data receiver. If the user is away out of range of the receiver for even a relatively short period, such as about 1 5 minutes, sensor data will be lost and the effectiveness of the system may be compromised.
  • the present invention is directed to diabetes management systems comprising a substantially continuous glucose sensor, an insulin delivery device and a remote controller.
  • the present invention is also directed to methods for managing diabetes with a diabetes management system.
  • FIG. 1 is a diagrammatic view of a diabetes management system in accordance with the present invention.
  • FIG 2 is a diagrammatic view of an integrated delivery device and sensor assembly in accordance with a preferred embodiment of the present invention.
  • FIG 3 is a diagrammatic view of a diabetes management system in accordance with the present invention.
  • FIG. 1 there is shown a diabetes management system
  • the basic components of the system 500 include an insulin delivery device 2000, a glucose sensor assembly 3000 and a remote controller 1000.
  • the system 500 preferably comprises a delivery device 2000.
  • the delivery device 2000 comprises a delivery device controller 2002 coupled to: a delivery device communication circuit 2001 , a delivery device memory
  • the delivery device controller may also be coupled to a delivery device output mechanism 2006.
  • the delivery device may also comprise a transcutaneous access tool 2004.
  • the delivery device controller 2002 may be a microprocessor adapted to cause the dispensing mechanism 2003 to dispense insulin in accordance with dispensing instructions stored in the delivery device memory 2005.
  • the delivery device 2000 receives the dispensing instructions from the remote controller 1000 through an RF signal received by the delivery device communication circuit 2001 and stores the dispensing instructions in the delivery device memory 2005.
  • the delivery device memory 2005 is sufficient to store the delivery device operating system as well as at least 72 hours of basal rate dispensing instructions.
  • the delivery device memory 2005 is at least about 8 kilobytes.
  • the delivery device memory 2005 is sufficient to store sensor data received from the sensor assembly 3000 in addition to the operating system and 72 hours of basal rate instruction data.
  • the delivery device controller 2002 may be programmed to compress and/or discard sensor data when the available delivery device memory 2005 is full.
  • the delivery device controller 2002 may also comprise a plurality of controllers.
  • the delivery device communication circuit 2001 preferably comprises an RF transceiver capable of receiving RF signals from the remote controller 1000.
  • the delivery device communication circuit 2001 is preferably capable of sending and receiving RF signals from the remote controller 1000 and the sensor assembly 3000.
  • the delivery device communication circuit 2001 is capable of sending and receiving RF signals from the remote controller 1000 and the sensor assembly 3000 over a distance of about 1 to 6 feet.
  • the dispensing mechanism 2003 may be any mechanism for dispensing insulin from a reservoir to a patient at a variable rate in accordance with programmed dispensing instructions.
  • Many suitable dispensing mechanisms 2003 are known to those skilled in the art, including programmable syringe pumps with drives capable of advancing a plunger in a syringe reservoir at a variable rate (see, for example, U.S. Pat. App. Ser. Nos. 10/261003, 10/907286, and 10/907287), programmable valve regulated pumps using one or more controllable valves to regulate the insulin delivery rate (see, for example, U.S. Patent Nos. 10/683659), and programmable peristaltic pumps.
  • the dispensing mechanism may include a fluid path connecting a reservoir to an exit port of the insulin delivery device.
  • the exit port may be adapted to be connected to a transcutaneous access tool 2004 or, preferably may include an integrated transcutaneous access tool (See, for example, U.S. patent No. 10/907286, and 10/907287).
  • the insulin delivery device 2000 also preferably includes a delivery device output mechanism 2006 for alerting the user of one or more conditions concerning the delivery device or the user's glucose level.
  • the delivery device output mechanism 2006 may be one or more devices capable of generating an audible, visible or tactile signal discernible by the user.
  • the delivery device output mechanism 2006 comprises at least an audible piezo alarm.
  • the delivery device output mechanism 2006 may comprise a mechanism for vibrating the delivery device 2000 and/or a visible warning light or a digital display.
  • the delivery device controller 2002 is adapted to control the delivery device output mechanism 2006 to provide different signals corresponding to different delivery device conditions and or user glucose level conditions.
  • the delivery device comprises no user input components.
  • the system 500 also preferably comprises a glucose sensor assembly 3000.
  • the sensor assembly 3000 comprises a sensor assembly controller 3002, coupled to a sensor assembly communication circuit 3001 , a sensor assembly memory 3005, and a glucose sensor 3003.
  • the sensor assembly controller 3002 may also be coupled to a sensor assembly output mechanism 3006.
  • the glucose sensor 3003 may be any glucose sensor adapted to continuously generate a signal representative of a user's glucose level.
  • the sensor 3003 may be adapted to generate a discrete signal representative of a user's glucose level, provided that repeated discrete signals may be generated by the sensor 3003 repeatedly and without user intervention each time a signal is generated.
  • the sensor 3003 generates a signal representative of the user's glucose level continuously or substantially continuously, where "substantially continuously" means at a frequency at which the gaps between readings are not clinically significant.
  • the sensor 3003 is a glucose sensor implanted in a user's blood vessel or other tissue, a subcutaneous glucose sensor, or a non-invasive sensor.
  • the sensor assembly controller 3002 is coupled to the sensor 3003 and is programmed to obtain a signal from the sensor on a continuous or substantially continuous basis.
  • the sensor assembly controller 3002 is programmed to store the sensor values in the sensor assembly memory 3005 until the sensor assembly controller 3002 receives a transmit data command via the sensor assembly communication circuit 3001 .
  • the sensor assembly controller 3002 may be programmed to transmit the sensor data to one or both of the remote controller 1000 or the delivery device 2000 in response to a transmit data command.
  • the sensor assembly controller 3002 may also be programmed to automatically send (i.e., without having received a transmit data command) an alarm signal to the delivery device 2000 in the event that the sensor 3003 detects a glucose level above or below a specified threshold or, in the event that the sensor assembly controller 3002 determines that a series of glucose sensor signals matches a predetermined pattern.
  • the alarm signal contains information identifying the nature of the recognized glucose level condition, such as, high, low, trending high or trending low.
  • the sensor assembly controller 3002 may be programmed to automatically send sensor data to the delivery device 2000 on a continuous or periodic basis rather than (or in addition to) in response to a transmit data command.
  • the sensor assembly memory 3005 is coupled to the sensor assembly controller and is used for storing programming instructions of the sensor assembly controller, communication data and/or sensor data.
  • the size of the sensor assembly memory 3005 depends upon whether, and for how long, sensor data will be retained in the sensor assembly 3000. In an embodiment where sensor data is retained in the sensor until a transmit data command is received, the sensor assembly memory is preferably sufficient to retain 24 hours worth of substantially continuous sensor data. Alternatively, the sensor assembly memory is sufficient to retain only a clinically significant amount of substantially continuous sensor data. A "clinically significant" amount of sensor data is an amount of sensor data useful for generating a suggested correction bolus. In such an embodiment, the sensor assembly memory 2005 would be sufficient to retain only about 6 hour of sensor data at a frequency of about once per minute.
  • the sensor assembly memory is about 2 to about 32 kilobytes.
  • the sensor assembly communication circuit 3001 preferably comprises an RF transceiver capable of receiving RF signals from the remote controller 1000 and/or the delivery device 2000.
  • the sensor assembly communication circuit 3001 is capable of sending and receiving RF signals from the remote controller 1000 and/or the delivery device 2000 over a distance of at least about 1 to 4 feet.
  • the sensor assembly controller 3002 may also be coupled to a sensor assembly output mechanism 3006 for alerting the user of one or more conditions concerning the user's glucose level.
  • the sensor assembly output mechanism 3006 may be one or more devices capable of generating an audible, visible or tactile signal discernible by the user.
  • the sensor assembly output mechanism 3006 comprises at least an audible piezo alarm.
  • the sensor assembly output mechanism 3006 may comprise a mechanism for vibrating the sensor assembly 3000 and/or a visible warning light.
  • the sensor assembly controller 3002 is adapted to control the sensor assembly output mechanism to provide different signals corresponding to different user glucose level conditions.
  • the sensor assembly is incorporated into the delivery device (FIG. 2).
  • one or more of the sensor assembly controller, sensor assembly memory, the sensor assembly user output, the sensor assembly user input may be the same as the corresponding delivery device components to avoid unnecessary duplication.
  • An exemplary delivery device with integrated sensor assembly is also shown in U.S. Patent App. No. 10/ 195745.
  • the system 500 also preferably comprises a remote controller 1000.
  • the remote controller 1000 comprises a remote controller controller 1002 coupled to a remote controller communication circuit 1001 , a remote controller user input 1007, a remote controller user output 1006, and a remote controller memory 1005.
  • the remote controller user input mechanism 1007 may be any user input mechanism enabling a user to input delivery instructions to be transmitted to the delivery device 2000, transmit data commands, or other information, to be sent to the sensor assembly 3000 and or the delivery device 2000, as well as any other information or instructions the user might input into the system 500.
  • the remote controller user input mechanism 1007 is one or both of a plurality of buttons (keyboard) and a touch screen.
  • the remote controller user input mechanism 1007 may also comprise a microphone and voice recognition software.
  • the remote controller user output mechanism 1006 may be any mechanism sufficient to communicate the information the user needs to operate the system 500 and interpret the sensor data from the sensor assembly via one or more of visible, audible or tactile signals.
  • the remote controller user output mechanism 1006 is a combination of a visible display screen of the type typically found in small portable personal computing devices and a device capable of generating a variety of different audible signals, such as a piezo alarm.
  • the remote controller communication circuit 1001 preferably comprises an RF transceiver capable of sending and receiving RF signals to/from the delivery device 2000 and/or the sensor assembly 3000.
  • the remote controller communication circuit 1001 is capable of sending and receiving RF signals from the delivery device 2000 and/or the sensor assembly 3000 over a distance of at least about 1 to 4 feet.
  • the embodiment of the system 500 described above is intended for the treatment of diabetes. However, the system 500 may also be adapted for the treatment of diseases other than diabetes where it is useful to deliver a medication on a continuous or substantially continuous basis and where it is also useful to monitor a physiological condition of the patient on a continuous or substantially continuous basis and where the user might adjust the delivery of the medication based on the monitored physiological condition.
  • the senor may be adapted to sense the corresponding physiological condition
  • the delivery device may be adapted to deliver the appropriate corresponding medication
  • the remote controller may be adapted to present the user with information and command options appropriate to treating the corresponding disease.
  • the present invention is also directed to methods for treating diabetes with a system comprising a delivery device, sensor assembly and remote controller.
  • the user is supplied with a diabetes management system comprising a sensor assembly a delivery device and a remote controller.
  • the sensor assembly senses the user's glucose level substantially continuously and stores the results in the sensor assembly memory.
  • the query causes the remote controller to send a sensor data transmit command to the sensor assembly.
  • the sensor assembly responds by transmitting the stored sensor data to the remote controller.
  • the remote controller preferably outputs the sensor data to the user.
  • the user is supplied with a diabetes management system comprising a sensor assembly a delivery device and a remote controller.
  • the sensor assembly senses the user's glucose level substantially continuously and stores the results in the sensor assembly memory.
  • the user queries the system with the remote controller.
  • the query causes the remote controller to send a sensor data transmit command to the sensor assembly.
  • the sensor assembly responds by transmitting the stored sensor data to the delivery device.
  • the delivery device then transmits the sensor data to the remote controller.
  • the remote controller preferably outputs the sensor data to the user.
  • the user is supplied with a diabetes management system comprising a sensor assembly a delivery device and a remote controller.
  • the sensor assembly senses the user's glucose level substantially continuously and stores the results in the sensor assembly memory.
  • the user queries the system with the remote controller.
  • the query causes the remote controller to send a sensor data transmit command to the delivery device.
  • the delivery device responds by transmitting a transmit data command to the sensor assembly.
  • the sensor assembly responds by transmitting the stored sensor data to the delivery device.
  • the delivery device then transmits the sensor data to the remote controller.
  • the remote controller preferably outputs the sensor data to the user.
  • the transmit data command may alternatively be triggered any time the user activates the remote controller regardless of whether the user intends to review the sensor data or calculate a bolus (or basal adjustment) using the sensor data.
  • the remote controller preferably, outputs the sensor data to the user in the form of a graph of the user's glucose level over time.
  • the remote controller may also use the sensor data (current and/or historical) in conjunction with a bolus estimation algorithm to generate a suggested bolus dose for the user to correct for any actual or projected deviation from the user's target glucose level or range.
  • the remote controller may use the sensor data in conjunction with some other algorithm to generate a suggested change to one or more of the user's pre-programmed basal rates.
  • the user is supplied with a diabetes management system comprising a sensor assembly a delivery device and a remote controller.
  • the sensor assembly senses the user's glucose level substantially continuously.
  • the sensor assembly substantially continuously compares the sensor data to one or more predetermined alert conditions.
  • the predetermined alert condition may be any condition or pattern that the user and/or the user's health care provide determines requires the user's attention. Typical alert conditions would include glucose level above a specified threshold, glucose level below a specified threshold, glucose level trending high or low at a predetermined rate, et al.
  • the sensor assembly detects a glucose level or a pattern that satisfies a predetermined alert condition, the sensor assembly notifies the user of the alert condition with the sensor assembly user output.
  • the sensor assembly detects a glucose level or a pattern that satisfies the alert condition, the sensor assembly transmits an alert signal to the delivery device.
  • the delivery device alerts the user of the existence the alert condition with the delivery device user output.
  • the sensor assembly and/or the delivery device provides different alert signals for different conditions so that the user knows the general nature of the alert without further interaction with the system.
  • the sensor assembly and/or the delivery device transmits the alert signal to the remote controller.
  • the sensor assembly and/or delivery device preferably retains the sensor data in the sensor assembly and/or delivery device memory until receiving a transmit sensor data command.
  • the sensor data may exceed the storage capacity of the sensor assembly or delivery device memory prior to receiving a transmit data command from the remote controller.
  • new data replaces the oldest data in a simple first in first out manner.
  • sensor assembly or delivery device memory is made available by thinning the retained sensor data starting with the oldest sensor data so that a portion of the oldest sensor data is retained, but at a reduced frequency. Thus, the newest retained sensor data is denser than the oldest retained sensor data.
  • At least the most recent 6 hours of substantially continuous sensor data is always retained in the sensor assembly or delivery device memory until a transmit data command is received.

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • Medical Informatics (AREA)
  • Veterinary Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • Primary Health Care (AREA)
  • Epidemiology (AREA)
  • Vascular Medicine (AREA)
  • Hematology (AREA)
  • Anesthesiology (AREA)
  • Physics & Mathematics (AREA)
  • Business, Economics & Management (AREA)
  • Biophysics (AREA)
  • General Business, Economics & Management (AREA)
  • Pathology (AREA)
  • Surgery (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Diabetes (AREA)
  • Optics & Photonics (AREA)
  • Emergency Medicine (AREA)
  • Computer Networks & Wireless Communication (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • External Artificial Organs (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)

Abstract

L'invention concerne des systèmes de gestion du diabète qui comprennent un glucomètre sensiblement constant, un dispositif d'apport d'insuline et une télécommande. Par ailleurs, l'invention concerne des procédés de gestion du diabète à l'aide d'un système de gestion du diabète.
PCT/US2006/060260 2005-10-27 2006-10-26 Systemes et procedes de gestion du diabete WO2007051139A2 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US59688005P 2005-10-27 2005-10-27
US60/596,880 2005-10-27

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WO2007051139A2 true WO2007051139A2 (fr) 2007-05-03
WO2007051139A3 WO2007051139A3 (fr) 2007-11-08

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WO2009072082A1 (fr) * 2007-12-06 2009-06-11 Edward Henry Mathews Installation et procédé pour le traitement du cancer
WO2010007573A1 (fr) * 2008-07-18 2010-01-21 Koninklijke Philips Electronics N.V. Appareil médical comprenant une télécommande
WO2010011805A1 (fr) * 2008-07-24 2010-01-28 Admetsys Corporation Dispositif et procédé pour échantillonner et mesurer automatiquement des substances sanguines à analyser
US7914499B2 (en) 2006-03-30 2011-03-29 Valeritas, Inc. Multi-cartridge fluid delivery device
US8070726B2 (en) 2003-04-23 2011-12-06 Valeritas, Inc. Hydraulically actuated pump for long duration medicament administration
US8939928B2 (en) 2009-07-23 2015-01-27 Becton, Dickinson And Company Medical device having capacitive coupling communication and energy harvesting
US8956291B2 (en) 2005-02-22 2015-02-17 Admetsys Corporation Balanced physiological monitoring and treatment system
US9066697B2 (en) 1998-04-30 2015-06-30 Abbott Diabetes Care Inc. Analyte monitoring device and methods of use
US9066694B2 (en) 1998-04-30 2015-06-30 Abbott Diabetes Care Inc. Analyte monitoring device and methods of use
US9066695B2 (en) 1998-04-30 2015-06-30 Abbott Diabetes Care Inc. Analyte monitoring device and methods of use
US9078607B2 (en) 2005-11-01 2015-07-14 Abbott Diabetes Care Inc. Analyte monitoring device and methods of use
US9089636B2 (en) 2004-07-02 2015-07-28 Valeritas, Inc. Methods and devices for delivering GLP-1 and uses thereof
US9242039B2 (en) 2009-09-29 2016-01-26 Admetsys Corporation System and method for differentiating containers in medication delivery
US9375529B2 (en) 2009-09-02 2016-06-28 Becton, Dickinson And Company Extended use medical device
US9480792B2 (en) 2010-11-30 2016-11-01 Becton, Dickinson And Company Ballistic microneedle infusion device
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US9660857B2 (en) 2007-12-07 2017-05-23 Roche Diabetes Care, Inc. Dynamic communication stack
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