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WO2005003087A3 - Oxazole derivatives as antibacterial agents - Google Patents

Oxazole derivatives as antibacterial agents Download PDF

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Publication number
WO2005003087A3
WO2005003087A3 PCT/IB2004/002131 IB2004002131W WO2005003087A3 WO 2005003087 A3 WO2005003087 A3 WO 2005003087A3 IB 2004002131 W IB2004002131 W IB 2004002131W WO 2005003087 A3 WO2005003087 A3 WO 2005003087A3
Authority
WO
WIPO (PCT)
Prior art keywords
antibacterial agents
oxazole derivatives
derivatives
pharmaceutically acceptable
general formula
Prior art date
Application number
PCT/IB2004/002131
Other languages
French (fr)
Other versions
WO2005003087A2 (en
Inventor
Satya Surya Visweswara Akella
Kasinathanan Mathiyazhagan
Matte Mariana Samuel
Shakti Singh Solanki
Vijayan Magesh
Shiv Kumar Agarwal
Original Assignee
Orchid Chemicals & Pharm Ltd
Satya Surya Visweswara Akella
Kasinathanan Mathiyazhagan
Matte Mariana Samuel
Shakti Singh Solanki
Vijayan Magesh
Shiv Kumar Agarwal
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Orchid Chemicals & Pharm Ltd, Satya Surya Visweswara Akella, Kasinathanan Mathiyazhagan, Matte Mariana Samuel, Shakti Singh Solanki, Vijayan Magesh, Shiv Kumar Agarwal filed Critical Orchid Chemicals & Pharm Ltd
Publication of WO2005003087A2 publication Critical patent/WO2005003087A2/en
Publication of WO2005003087A3 publication Critical patent/WO2005003087A3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

The present invention provides novel compounds of the general formula (I), their derivatives, their analogs, their tautomeric forms, their stereoisomers, their polymorphs, their hydrates, their solvates, their pharmaceutically acceptable salts and pharmaceutically acceptable compositions containing them. The present invention more particularly provides novel oxazolidinone derivatives of the general formula (I).
PCT/IB2004/002131 2003-07-01 2004-06-28 Oxazole derivatives as antibacterial agents WO2005003087A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN539CH2003 2003-07-01
IN539/CHE/2003 2003-07-01

Publications (2)

Publication Number Publication Date
WO2005003087A2 WO2005003087A2 (en) 2005-01-13
WO2005003087A3 true WO2005003087A3 (en) 2005-03-17

Family

ID=33561911

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IB2004/002131 WO2005003087A2 (en) 2003-07-01 2004-06-28 Oxazole derivatives as antibacterial agents

Country Status (1)

Country Link
WO (1) WO2005003087A2 (en)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2528089C (en) 2003-06-03 2015-11-24 Rib-X Pharmaceuticals, Inc. Biaryl heterocyclic compounds and methods of making and using the same
US8324398B2 (en) 2003-06-03 2012-12-04 Rib-X Pharmaceuticals, Inc. Process for the synthesis of biaryl oxazolidinones
JP2007514782A (en) 2003-12-17 2007-06-07 リブ−エックス ファーマシューティカルズ，インコーポレイテッド Halogenated biaryl heterocyclic compounds and methods for making and using the same
TW200626155A (en) 2004-09-20 2006-08-01 Xenon Pharmaceuticals Inc Heterocyclic derivatives and their use as therapeutic agents
WO2006034440A2 (en) * 2004-09-20 2006-03-30 Xenon Pharmaceuticals Inc. Heterocyclic derivatives and their use as stearoyl-coa desaturase inhibitors
TW200626572A (en) 2004-09-20 2006-08-01 Xenon Pharmaceuticals Inc Heterocyclic derivatives and their use as therapeutic agents
WO2006034441A1 (en) 2004-09-20 2006-03-30 Xenon Pharmaceuticals Inc. Heterocyclic derivatives and their use as stearoyl-coa desaturase inhibitors
JP5043668B2 (en) 2004-09-20 2012-10-10 ゼノン・ファーマシューティカルズ・インコーポレイテッド Heterocyclic derivatives and their use as therapeutic agents
AR051093A1 (en) 2004-09-20 2006-12-20 Xenon Pharmaceuticals Inc HETEROCICLIC DERIVATIVES AND THEIR USE AS INHIBITORS OF ESTEAROIL-COA DESATURASA
MX2007003318A (en) 2004-09-20 2007-05-18 Xenon Pharmaceuticals Inc Heterocyclic derivatives for the treatment of diseases mediated by stearoyl-coa desaturase enzymes.
MX2007015216A (en) 2005-06-03 2008-02-22 Xenon Pharmaceuticals Inc Aminothiazole derivatives as human stearoyl-coa desaturase inhibitors.
WO2006133397A2 (en) 2005-06-08 2006-12-14 Rib-X Pharmaceuticals, Inc. Process for the synthesis of triazoles
JP2008545760A (en) * 2005-06-09 2008-12-18 メルク フロスト カナダ リミテツド Azacyclohexane derivatives as inhibitors of stearoyl-coenzyme A delta-9 desaturase
WO2008029266A1 (en) * 2006-09-08 2008-03-13 Glenmark Pharmaceuticals S.A. Stearoyl coa desaturase inhibitors
TWI498115B (en) * 2007-12-27 2015-09-01 Daiichi Sankyo Co Ltd Imidazole carbonyl compounds
AU2009318783A1 (en) 2008-11-20 2011-06-23 Panacea Biotec Ltd. Novel antimicrobials
EP2445887B1 (en) 2009-06-26 2014-11-05 Panacea Biotec Limited Novel azabicyclohexanes
WO2018170664A1 (en) 2017-03-20 2018-09-27 Merck Sharp & Dohme Corp. Oxazolidinone compounds and methods of use thereof as antibacterial agents

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000021960A1 (en) * 1998-10-09 2000-04-20 Astrazeneca Ab Heterocyclyl amino methyloxa zolidinones as antibacterials
WO2002006278A1 (en) * 2000-07-17 2002-01-24 Ranbaxy Laboratories Limited Oxazolidinone derivatives as antimicrobials
WO2004009587A1 (en) * 2002-07-22 2004-01-29 Orchid Chemicals & Pharmaceuticals Ltd Oxazolidinone derivatives as antibacterial agents

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000021960A1 (en) * 1998-10-09 2000-04-20 Astrazeneca Ab Heterocyclyl amino methyloxa zolidinones as antibacterials
WO2002006278A1 (en) * 2000-07-17 2002-01-24 Ranbaxy Laboratories Limited Oxazolidinone derivatives as antimicrobials
WO2004009587A1 (en) * 2002-07-22 2004-01-29 Orchid Chemicals & Pharmaceuticals Ltd Oxazolidinone derivatives as antibacterial agents

Also Published As

Publication number Publication date
WO2005003087A2 (en) 2005-01-13

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