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WO2005074898A3 - Composition comprising (s) pantoprazole and an antibiotic for treating helicobacter pylori - Google Patents

Composition comprising (s) pantoprazole and an antibiotic for treating helicobacter pylori Download PDF

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Publication number
WO2005074898A3
WO2005074898A3 PCT/EP2005/050337 EP2005050337W WO2005074898A3 WO 2005074898 A3 WO2005074898 A3 WO 2005074898A3 EP 2005050337 W EP2005050337 W EP 2005050337W WO 2005074898 A3 WO2005074898 A3 WO 2005074898A3
Authority
WO
WIPO (PCT)
Prior art keywords
pantoprazole
antibiotic
composition
helicobacter pylori
treating helicobacter
Prior art date
Application number
PCT/EP2005/050337
Other languages
French (fr)
Other versions
WO2005074898A2 (en
Inventor
Reinhard Huber
Bernhard Kohl
Wolfgang Kromer
Wolfgang-Alexander Simon
Original Assignee
Altana Pharma Ag
Reinhard Huber
Bernhard Kohl
Wolfgang Kromer
Wolfgang-Alexander Simon
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Altana Pharma Ag, Reinhard Huber, Bernhard Kohl, Wolfgang Kromer, Wolfgang-Alexander Simon filed Critical Altana Pharma Ag
Publication of WO2005074898A2 publication Critical patent/WO2005074898A2/en
Publication of WO2005074898A3 publication Critical patent/WO2005074898A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/429—Thiazoles condensed with heterocyclic ring systems
    • A61K31/43—Compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula, e.g. penicillins, penems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

The present invention relates to pharmaceutical compositions comprising (s) pantoprazole and a helicobacter inhibiting antimicrobial agent, and their use in treating or preventing gastrointestinal disorders, in particular disorders caused or exacerbated by helicobacter infection and secreted gastric acid.
PCT/EP2005/050337 2004-01-28 2005-01-27 Composition comprising (s) pantoprazole and an antibiotic for treating helicobacter pylori WO2005074898A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP04001756 2004-01-28
EP04001756.8 2004-01-28

Publications (2)

Publication Number Publication Date
WO2005074898A2 WO2005074898A2 (en) 2005-08-18
WO2005074898A3 true WO2005074898A3 (en) 2006-07-27

Family

ID=34833547

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2005/050337 WO2005074898A2 (en) 2004-01-28 2005-01-27 Composition comprising (s) pantoprazole and an antibiotic for treating helicobacter pylori

Country Status (1)

Country Link
WO (1) WO2005074898A2 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI463998B (en) * 2009-12-31 2014-12-11 Synmosa Biopharma Corp Amoxicillin and clomycin have a high absorption rate of pharmaceutical ingredients
CN104814964B (en) * 2015-04-16 2018-07-31 广东赛烽医药科技有限公司 A kind of pharmaceutical composition, the preparation method and applications of anti-stomach Helicobacter pylori

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1992003135A1 (en) * 1990-08-24 1992-03-05 Byk Gulden Lomberg Chemische Fabrik Gmbh Pharmaceutical compositions containing 5-difluoromethoxy-2-[(3,4-dimethoxy-2-pyridyl) methylsulfinyl] benzimidazole and an anti-helicobacter agent for the treatment of gastrointestinal disorders
US5888535A (en) * 1993-04-27 1999-03-30 Sepracor Inc. Methods and compositions for treating gastric disorders using optically pure (-) pantoprazole
WO2000010995A1 (en) * 1998-08-18 2000-03-02 Byk Gulden Lomberg Chemische Fabrik Gmbh Novel salt form of pantoprazole
WO2000074654A1 (en) * 1999-06-07 2000-12-14 Byk Gulden Lomberg Chemische Fabrik Gmbh Novel preparation and administration form comprising an acid-labile active compound
US20030136698A1 (en) * 2000-06-27 2003-07-24 Andreas Klatt Medicinal product package for eradication therapy

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1992003135A1 (en) * 1990-08-24 1992-03-05 Byk Gulden Lomberg Chemische Fabrik Gmbh Pharmaceutical compositions containing 5-difluoromethoxy-2-[(3,4-dimethoxy-2-pyridyl) methylsulfinyl] benzimidazole and an anti-helicobacter agent for the treatment of gastrointestinal disorders
US5888535A (en) * 1993-04-27 1999-03-30 Sepracor Inc. Methods and compositions for treating gastric disorders using optically pure (-) pantoprazole
WO2000010995A1 (en) * 1998-08-18 2000-03-02 Byk Gulden Lomberg Chemische Fabrik Gmbh Novel salt form of pantoprazole
WO2000074654A1 (en) * 1999-06-07 2000-12-14 Byk Gulden Lomberg Chemische Fabrik Gmbh Novel preparation and administration form comprising an acid-labile active compound
US20030136698A1 (en) * 2000-06-27 2003-07-24 Andreas Klatt Medicinal product package for eradication therapy

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
KALE-PRADHAN PRAMODINI B ET AL: "Esomeprazole for acid peptic disorders", ANNALS OF PHARMACOTHERAPY, vol. 36, no. 4, April 2002 (2002-04-01), pages 655 - 663, XP009030827, ISSN: 1060-0280 *
TANAKA MAKOTO ET AL: "Stereoselective pharmacokinetics of pantoprazole, a proton pump inhibitor, in extensive and poor metabolizers of S-mephenytoin", CLINICAL PHARMACOLOGY AND THERAPEUTICS, vol. 69, no. 3, March 2001 (2001-03-01), pages 108 - 113, XP009030871, ISSN: 0009-9236 *

Also Published As

Publication number Publication date
WO2005074898A2 (en) 2005-08-18

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