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WO2003057879A1 - Udp-n-acetyl-d-galactosamine:polypeptide n-acetylgalactosamine transferase et acide nucleique la codant - Google Patents

Udp-n-acetyl-d-galactosamine:polypeptide n-acetylgalactosamine transferase et acide nucleique la codant Download PDF

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Publication number
WO2003057879A1
WO2003057879A1 PCT/JP2002/013760 JP0213760W WO03057879A1 WO 2003057879 A1 WO2003057879 A1 WO 2003057879A1 JP 0213760 W JP0213760 W JP 0213760W WO 03057879 A1 WO03057879 A1 WO 03057879A1
Authority
WO
WIPO (PCT)
Prior art keywords
nucleic acid
acid encoding
galactosamine
polypeptide
acetyl
Prior art date
Application number
PCT/JP2002/013760
Other languages
English (en)
Japanese (ja)
Inventor
Hisashi Narimatsu
Yan Zhang
Niro Inaba
Original Assignee
National Institute Of Advanced Industrial Science And Technology
Amersham Biosciences K.K.
Fujirebio Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by National Institute Of Advanced Industrial Science And Technology, Amersham Biosciences K.K., Fujirebio Inc. filed Critical National Institute Of Advanced Industrial Science And Technology
Priority to AU2002357525A priority Critical patent/AU2002357525A1/en
Publication of WO2003057879A1 publication Critical patent/WO2003057879A1/fr

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1048—Glycosyltransferases (2.4)
    • C12N9/1051—Hexosyltransferases (2.4.1)

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  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Saccharide Compounds (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

L'invention concerne une enzyme possédant une activité permettant de transférer N-acétylglucosamine vers un groupe hydroxyle d'un résidu de sérine ou de thréonine dans une apoenzyme ou une séquence de peptides via une liaison α-1, et un acide nucléique codant l'enzyme. L'enzyme susmentionnée possède la séquence d'acides aminés représentée par SEQ ID NO:1. Le gène susmentionné a la séquence de base représentée par SEQ ID NO:2.
PCT/JP2002/013760 2001-12-28 2002-12-27 Udp-n-acetyl-d-galactosamine:polypeptide n-acetylgalactosamine transferase et acide nucleique la codant WO2003057879A1 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2002357525A AU2002357525A1 (en) 2001-12-28 2002-12-27 Novel udp-n-acetyl-d-galactosamine:polypeptide n-acetylgalactosamine transferase and nucleic acid encoding the same

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2001401455A JP2003199573A (ja) 2001-12-28 2001-12-28 新規ｕｄｐ−ｎ−アセチル−ｄ−ガラクトサミン：ポリペプチドｎ−アセチルガラクトサミン転移酵素及びこれをコードする核酸
JP2001-401455 2001-12-28

Publications (1)

Publication Number Publication Date
WO2003057879A1 true WO2003057879A1 (fr) 2003-07-17

Family

ID=19189778

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/JP2002/013760 WO2003057879A1 (fr) 2001-12-28 2002-12-27 Udp-n-acetyl-d-galactosamine:polypeptide n-acetylgalactosamine transferase et acide nucleique la codant

Country Status (3)

Country Link
JP (1) JP2003199573A (fr)
AU (1) AU2002357525A1 (fr)
WO (1) WO2003057879A1 (fr)

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994026906A2 (fr) * 1993-05-14 1994-11-24 The Upjohn Company UN ADN CLONE CODANT UNE UDT-GALNAc:POLYPEPTIDE, N-ACETYLGALACTOSAMINYLTRANSFERASE
WO1997013783A1 (fr) * 1995-10-09 1997-04-17 Pharmacia & Upjohn Company Polypeptide accepteur pour une enzyme n-acetylgalactosaminyltransferase
WO2002064975A1 (fr) * 2001-02-13 2002-08-22 Richard Arel Appareil a moteur actionne par gravite

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994026906A2 (fr) * 1993-05-14 1994-11-24 The Upjohn Company UN ADN CLONE CODANT UNE UDT-GALNAc:POLYPEPTIDE, N-ACETYLGALACTOSAMINYLTRANSFERASE
WO1997013783A1 (fr) * 1995-10-09 1997-04-17 Pharmacia & Upjohn Company Polypeptide accepteur pour une enzyme n-acetylgalactosaminyltransferase
WO2002064975A1 (fr) * 2001-02-13 2002-08-22 Richard Arel Appareil a moteur actionne par gravite

Non-Patent Citations (6)

* Cited by examiner, † Cited by third party
Title
HAGEN F.K. ET AL.: "cDNA cloning and expression of a novel UDP-N-acetyl-D-galactosamine: polypeptide N-acetylgalactosaminyltransferase", J. BIOL. CHEM., vol. 272, no. 21, 1997, pages 13843 - 13848, XP002965843 *
HAGEN F.K. ET AL.: "Cloning and sequence homology of a rat UDP-GalNAc: polypeptide N-acetylgalactosaminyltransferase", GLYCOCONJ. J., vol. 12, no. 6, 1995, pages 901 - 909, XP002965845 *
HOMA F.L. ET AL.: "Isolation and expression of a cDNA clone encoding a bovine UDP-GalNAc: polypeptide N-acetylgalactosaminyltransferase", J. BIOL. CHEM., vol. 268, no. 17, 1993, pages 12609 - 12616, XP002965844 *
MEURER J.A. ET AL.: "cDNA cloning, expression and chromosomal localization of a human UDP-GalkNac: polypeptide, N-acetylgalactosaminyltransferase", J. BIOCHEM., vol. 118, no. 3, 1995, TOKYO, pages 568 - 574, XP002965842 *
WHITE T. ET AL.: "Purification and cDNA cloning of a human UDP-N-acetyl-alpha-D-galactosamine: polypeptide N-acetylgalactosaminyltransferase", J. BIOL. CHEM., vol. 270, no. 41, 1995, pages 24156 - 24165, XP002924497 *
YOSHIDA A. ET AL.: "Cloning and expression of a piorcine UDP-GalNAc: polypeptide N-acetylgalactosaminyltransferase", GLYCOCONJ. J., vol. 12, no. 6, 1995, pages 824 - 828, XP002965846 *

Also Published As

Publication number Publication date
JP2003199573A (ja) 2003-07-15
AU2002357525A1 (en) 2003-07-24

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