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WO2002100843A1 - Phenoxazine compounds, the compositions containing them and their medicinal uses - Google Patents

Phenoxazine compounds, the compositions containing them and their medicinal uses Download PDF

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Publication number
WO2002100843A1
WO2002100843A1 PCT/CN2001/000968 CN0100968W WO02100843A1 WO 2002100843 A1 WO2002100843 A1 WO 2002100843A1 CN 0100968 W CN0100968 W CN 0100968W WO 02100843 A1 WO02100843 A1 WO 02100843A1
Authority
WO
WIPO (PCT)
Prior art keywords
compositions containing
medicinal uses
phenoxazine compounds
phenoxazine
compounds
Prior art date
Application number
PCT/CN2001/000968
Other languages
French (fr)
Chinese (zh)
Inventor
Jianqing Lu
Original Assignee
Jianqing Lu
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Jianqing Lu filed Critical Jianqing Lu
Priority to CN01801106A priority Critical patent/CN1366519A/en
Priority to PCT/CN2001/000968 priority patent/WO2002100843A1/en
Publication of WO2002100843A1 publication Critical patent/WO2002100843A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D265/28—1,4-Oxazines; Hydrogenated 1,4-oxazines
    • C07D265/34—1,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings
    • C07D265/38—[b, e]-condensed with two six-membered rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D265/28—1,4-Oxazines; Hydrogenated 1,4-oxazines
    • C07D265/34—1,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

The invention relates to the phenoxazine compounds of formulae I, and the pharmaceutical acceptable salts, esters, amides and prodrugs thereof, to the pharmaceutical compositions containing them, to the use of the preparation of the medicines for inhibiting the starchy protein coagulate. The definitions of R1, R2 and R in formulae I are described in the specification.
PCT/CN2001/000968 2001-06-13 2001-06-13 Phenoxazine compounds, the compositions containing them and their medicinal uses WO2002100843A1 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
CN01801106A CN1366519A (en) 2001-06-13 2001-06-13 Phenoxazine compounds, its pharmaceutical compositions and medical use
PCT/CN2001/000968 WO2002100843A1 (en) 2001-06-13 2001-06-13 Phenoxazine compounds, the compositions containing them and their medicinal uses

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/CN2001/000968 WO2002100843A1 (en) 2001-06-13 2001-06-13 Phenoxazine compounds, the compositions containing them and their medicinal uses

Publications (1)

Publication Number Publication Date
WO2002100843A1 true WO2002100843A1 (en) 2002-12-19

Family

ID=4574812

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/CN2001/000968 WO2002100843A1 (en) 2001-06-13 2001-06-13 Phenoxazine compounds, the compositions containing them and their medicinal uses

Country Status (2)

Country Link
CN (1) CN1366519A (en)
WO (1) WO2002100843A1 (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005118580A3 (en) * 2004-05-12 2006-08-03 Us Gov Health & Human Serv Tricyclic compounds as inhibitors of the hypoxic signaling pathway
GB2433071A (en) * 2005-12-05 2007-06-13 Kontrakt Technology Ltd Organic acids comprising planar conjugated heterocyclic molecular system, & photoelectric layer thereof with rodlike supramolecules for use in solar cell

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103819423B (en) * 2014-02-13 2015-04-15 江苏傲伦达科技实业股份有限公司 Method for synthesizing N-aryl-phenoxazine compounds
CN109512824B (en) * 2018-11-14 2021-07-16 吉林大学 Application of resazurin as bovine insulin amyloid fiber inhibitor

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0156347A2 (en) * 1984-03-29 1985-10-02 Roche Diagnostics GmbH Glycosides of resofurin derivatives, method for their preparation and their use in the determination of the activity of glycosidases
CN1086825A (en) * 1992-08-31 1994-05-18 弗·哈夫曼-拉罗切有限公司 Three ring and tetracyclic compounds
US5498542A (en) * 1994-09-29 1996-03-12 Bayer Corporation Electrode mediators for regeneration of NADH and NADPH

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0156347A2 (en) * 1984-03-29 1985-10-02 Roche Diagnostics GmbH Glycosides of resofurin derivatives, method for their preparation and their use in the determination of the activity of glycosidases
CN1086825A (en) * 1992-08-31 1994-05-18 弗·哈夫曼-拉罗切有限公司 Three ring and tetracyclic compounds
US5498542A (en) * 1994-09-29 1996-03-12 Bayer Corporation Electrode mediators for regeneration of NADH and NADPH

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005118580A3 (en) * 2004-05-12 2006-08-03 Us Gov Health & Human Serv Tricyclic compounds as inhibitors of the hypoxic signaling pathway
GB2433071A (en) * 2005-12-05 2007-06-13 Kontrakt Technology Ltd Organic acids comprising planar conjugated heterocyclic molecular system, & photoelectric layer thereof with rodlike supramolecules for use in solar cell

Also Published As

Publication number Publication date
CN1366519A (en) 2002-08-28

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