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WO2002057421A3 - Human tumor necrosis factor receptors tr13 and tr14 - Google Patents

Human tumor necrosis factor receptors tr13 and tr14 Download PDF

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Publication number
WO2002057421A3
WO2002057421A3 PCT/US2002/001139 US0201139W WO02057421A3 WO 2002057421 A3 WO2002057421 A3 WO 2002057421A3 US 0201139 W US0201139 W US 0201139W WO 02057421 A3 WO02057421 A3 WO 02057421A3
Authority
WO
WIPO (PCT)
Prior art keywords
necrosis factor
tumor necrosis
human tumor
factor receptors
proteins
Prior art date
Application number
PCT/US2002/001139
Other languages
French (fr)
Other versions
WO2002057421A2 (en
Inventor
Jian Ni
Kevin P Baker
Steven M Ruben
Paul E Young
Original Assignee
Human Genome Sciences Inc
Jian Ni
Kevin P Baker
Steven M Ruben
Paul E Young
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Human Genome Sciences Inc, Jian Ni, Kevin P Baker, Steven M Ruben, Paul E Young filed Critical Human Genome Sciences Inc
Priority to AU2002246999A priority Critical patent/AU2002246999A1/en
Publication of WO2002057421A2 publication Critical patent/WO2002057421A2/en
Publication of WO2002057421A3 publication Critical patent/WO2002057421A3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70578—NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cell Biology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

The present invention relates to two novel proteins, TR13 and TR14, which are members of the tumor necrosis factor (TNF) receptor superfamily. In particluar, isolated nucleic acid molecules are provided encoding the human TR13 and TR14 proteins. TR13 and TR14 polypeptides are also provided as are vectors, host cells, and recombinant methods for producing the same. The invention further relates to screening methods for identifying agonists and antagonists of TR13 and TR14.
PCT/US2002/001139 2001-01-17 2002-01-16 Human tumor necrosis factor receptors tr13 and tr14 WO2002057421A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2002246999A AU2002246999A1 (en) 2001-01-17 2002-01-16 Human tumor necrosis factor receptors tr13 and tr14

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US26196001P 2001-01-17 2001-01-17
US60/261,960 2001-01-17

Publications (2)

Publication Number Publication Date
WO2002057421A2 WO2002057421A2 (en) 2002-07-25
WO2002057421A3 true WO2002057421A3 (en) 2003-04-03

Family

ID=22995608

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2002/001139 WO2002057421A2 (en) 2001-01-17 2002-01-16 Human tumor necrosis factor receptors tr13 and tr14

Country Status (2)

Country Link
AU (1) AU2002246999A1 (en)
WO (1) WO2002057421A2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CZ301561B6 (en) * 2007-12-04 2010-04-14 Výzkumný ústav živocišné výroby, v. v. i. Pharmaceutical composition to prevent and suppress coccidia

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001005834A1 (en) * 1999-07-16 2001-01-25 Human Genome Sciences, Inc. Human tumor necrosis factor receptors tr13 and tr14

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001005834A1 (en) * 1999-07-16 2001-01-25 Human Genome Sciences, Inc. Human tumor necrosis factor receptors tr13 and tr14

Also Published As

Publication number Publication date
AU2002246999A1 (en) 2002-07-30
WO2002057421A2 (en) 2002-07-25

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