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WO2002049524A1 - Applicator for laser-surgery and a method for the production thereof - Google Patents

Applicator for laser-surgery and a method for the production thereof Download PDF

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Publication number
WO2002049524A1
WO2002049524A1 PCT/DE2001/004709 DE0104709W WO0249524A1 WO 2002049524 A1 WO2002049524 A1 WO 2002049524A1 DE 0104709 W DE0104709 W DE 0104709W WO 0249524 A1 WO0249524 A1 WO 0249524A1
Authority
WO
WIPO (PCT)
Prior art keywords
glass
distal end
glass sleeve
sleeve
laser surgical
Prior art date
Application number
PCT/DE2001/004709
Other languages
German (de)
French (fr)
Inventor
Wolfgang Illich
Thomas Müller
Original Assignee
Dornier Medtech Holding International Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dornier Medtech Holding International Gmbh filed Critical Dornier Medtech Holding International Gmbh
Publication of WO2002049524A1 publication Critical patent/WO2002049524A1/en

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/18—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves
    • A61B18/20—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using laser
    • A61B18/22—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using laser the beam being directed along or through a flexible conduit, e.g. an optical fibre; Couplings or hand-pieces therefor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/18—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves
    • A61B18/20—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using laser
    • A61B18/22—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using laser the beam being directed along or through a flexible conduit, e.g. an optical fibre; Couplings or hand-pieces therefor
    • A61B2018/2255—Optical elements at the distal end of probe tips
    • A61B2018/2261—Optical elements at the distal end of probe tips with scattering, diffusion or dispersion of light
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/18—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves
    • A61B18/20—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using laser
    • A61B18/22—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using laser the beam being directed along or through a flexible conduit, e.g. an optical fibre; Couplings or hand-pieces therefor
    • A61B2018/2255—Optical elements at the distal end of probe tips
    • A61B2018/2266—Optical elements at the distal end of probe tips with a lens, e.g. ball tipped

Definitions

  • the invention relates to a laser surgical applicator and method for its production according to the preamble of the respective main claims.
  • the glass envelope consists of homogeneously constructed quartz glass.
  • the laser radiation emerging from the light guide is partially returned in the quartz glass.
  • the proximal end of the glass envelope it is connected to the jacket of the light guide.
  • this connection is an adhesive connection with limited temperature resistance.
  • the described return of the radiation in the glass envelope can damage the adhesive connection between the glass envelope and the jacket, in particular when using higher laser light powers.
  • the considerations that led to the development of the present invention were based on the fact that by using a glass envelope made of scattering material, the laser light is emitted to the outside and is not absorbed within the glass envelope.
  • the heating that occurs when the laser light is absorbed advantageously does not take place.
  • the adhesive is not thermally stressed.
  • the inventive consideration was made that the material properties of the glass envelope when the actual light guide consisting of a glass fiber is melted changed.
  • the term "the actual light guide” is used here because only the glass fiber and not the other parts such as cladding and protective cover are connected to the glass cover.
  • FIG. 1 shows an optical waveguide and the glass sleeve before the assembly.
  • FIG. 2 shows the optical waveguide and the glass casing after the assembly.
  • the optical waveguide 1 consists of a glass fiber 2, which is surrounded by a cladding 3, the cladding 3 is surrounded by the protective jacket 4 of the optical waveguide 1.
  • a glass envelope 5 is partially hollow. The broken line indicates the cavity 6, into which the optical waveguide 1 can be inserted.
  • the distal end of the optical waveguide is prepared to be inserted into a glass envelope 5 sintered from glass powder.
  • the cladding 3 has been removed from the glass fiber 2 and part of the protective jacket 4 has also been removed.
  • the optical waveguide 1 prepared in this way can be inserted into the cavity 6 up to the distal end 7 of the glass envelope 5.
  • the distal end of the glass fiber 2 is then fused to the distal end 7 of the glass envelope 5 in a method not shown here.
  • FIG. 2 shows the applicator according to the invention after the glass fiber 2 and the glass envelope 5 have been fused.
  • the partial change in the material properties in the region of the fusion now leads to the distal end 7 of the glass envelope becoming transparent and the laser light 10 being able to leave the glass envelope 5 there distally ,
  • the proximal end 8 of the glass envelope 5 is glued to the protective jacket 4.
  • the glue point is designated 9.
  • the remaining area 10 of the glass envelope 5 remains in the original, opaque state, in this state the remaining area 10 behaves in a highly scattering manner and the laser light is emitted to the outside. As a result, the laser light is not returned in the glass envelope 5, and there is no increased temperature at the adhesive point.
  • the glass envelope 5 can consist of so-called “sintered” glass, which due to the porous structure strongly scatters the incident light.
  • the sintered body passes through several sintering phases from powdery to homogeneously transparent, so that the scattering properties can be set almost arbitrarily.
  • the glass material of the glass envelope 5 can also be shaped again.
  • the distal end 6 of the glass envelope 5 can be rounded off or can be shaped into a lens with certain optical properties.

Landscapes

  • Health & Medical Sciences (AREA)
  • Surgery (AREA)
  • Physics & Mathematics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medical Informatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Electromagnetism (AREA)
  • Optics & Photonics (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Otolaryngology (AREA)
  • Molecular Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Laser Surgery Devices (AREA)

Abstract

The invention relates to an applicator, consisting of an optical waveguide (1) and a glass sheath (5). The optical waveguide (1) and the glass sheath (5) are fused together. The glass sheath (5) is first opaque and diffuses incident light. When the glass sheath (5) is fused with the optical waveguide (1), the sheath becomes transparent in the fused section (6). The remaining section of the glass sheath (5) remains opaque.

Description

Laserchirurgischer Applikator und Verfahren zu dessen HerstellungLaser surgical applicator and method for its manufacture
Die Erfindung betrifft einen Laserchirurgischer Applikator und Verfahren zu dessen Herstellung gemäß dem Oberbegriff der jeweiligen Hauptansprüche.The invention relates to a laser surgical applicator and method for its production according to the preamble of the respective main claims.
Ein derartiger laserchirurgischer Applikator und ein derartiges Verfahren ist beispielsweise aus der DE 195 46447 AI bekannt. Bei dem dort beschriebenen laserchirurgischen Applikator besteht die Glashülle aus homogen aufgebautem Quarzglas.Such a laser surgical applicator and such a method is known for example from DE 195 46447 AI. In the laser surgical applicator described there, the glass envelope consists of homogeneously constructed quartz glass.
Die aus dem Lichtleiter austretende Laserstrahlung wird im Quarzglas teilweise zurückgeführt. Am proximalen Ende der Glashülle ist diese mit dem Mantel des Lichtleiters verbunden. Üblicherweise ist diese Verbindung eine Klebeverbindung mit begrenzter Temperaturbeständigkeit. Durch die beschriebene Rückführung der Strahlung in der Glashülle kann insbesondere beim Einsatz von höheren Laserlichtleistungen die Klebeverbindung zwischen Glashülle und Mantel geschädigt werden.The laser radiation emerging from the light guide is partially returned in the quartz glass. At the proximal end of the glass envelope, it is connected to the jacket of the light guide. Usually this connection is an adhesive connection with limited temperature resistance. The described return of the radiation in the glass envelope can damage the adhesive connection between the glass envelope and the jacket, in particular when using higher laser light powers.
Es ist Aufgabe der Erfindung, den bekannten Applikator so weiterzubilden und ein Verfahren zu dessen Herstellung anzugeben, dass die Erwärmung der Verbindungsstelle durch das absorbierte Laserlicht verringert wird.It is an object of the invention to further develop the known applicator and to specify a method for its production that the heating of the connection point is reduced by the absorbed laser light.
Diese Aufgabe wird durch das kennzeichnende Merkmal von Anspruch 1 und 7 gelöst.This object is solved by the characterizing feature of claims 1 and 7.
Die jeweiligen Unteransprüche betreffen Weiterbildungen und/oder besonders vorteilhafte Ausgestaltungen der Erfindung.The respective subclaims relate to further developments and / or particularly advantageous refinements of the invention.
Die Überlegungen, die zum Entstehen der vorliegenden Erfindung führten gingen davon aus, dass durch den Einsatz einer Glashülle aus streuendem Material das Laserlicht nach aussen abgestrahlt wird und nicht innerhalb der Glashülle absorbiert wird. Die beim Absorbieren des Laserlichts auftretende Erwärmung findet vorteilhafterweise nicht statt. Die Klebung wird nicht thermisch belastet.The considerations that led to the development of the present invention were based on the fact that by using a glass envelope made of scattering material, the laser light is emitted to the outside and is not absorbed within the glass envelope. The heating that occurs when the laser light is absorbed advantageously does not take place. The adhesive is not thermally stressed.
Weiters wurde die erfinderische Überlegung getätigt, dass sich die Materialbeschaffenheit der Glashülle beim Verschmelzen des aus einer Glasfaser bestehenden eigentlichen Lichtleiters verändert. Es wird hier von „dem eigentlichen Lichtleiter" gesprochen, weil hier nur die Glasfaser und nicht die übrigen Teile wie Cladding und Schutzhülle mit der Glashülle verbunden werden.Furthermore, the inventive consideration was made that the material properties of the glass envelope when the actual light guide consisting of a glass fiber is melted changed. The term "the actual light guide" is used here because only the glass fiber and not the other parts such as cladding and protective cover are connected to the glass cover.
Nachfolgend ist die Erfindung anhand zweier Figuren näher erläutert.The invention is explained in more detail below with reference to two figures.
Es zeigen:Show it:
Fig.1 einen Lichtwellenleiter und die Glashülse vor dem Zusammenfügen Fig.2 den Lichtwellenleiter und die Glashülle nach dem Zusammenfügen.1 shows an optical waveguide and the glass sleeve before the assembly. FIG. 2 shows the optical waveguide and the glass casing after the assembly.
Der Lichtwellenleiter 1 besteht aus einer Glasfaser 2, die von einem Cladding 3 umgeben ist, das Cladding 3 ist vom Schutzmantel 4 des Lichtwellenleiters 1 umgeben. Eine Glashülle 5 ist teilweise hohl ausgebildet. Die unterbrochene Linie deutet den Hohlraum 6 an, in welchen der Lichtwellenleiter 1 einschiebbar ist.The optical waveguide 1 consists of a glass fiber 2, which is surrounded by a cladding 3, the cladding 3 is surrounded by the protective jacket 4 of the optical waveguide 1. A glass envelope 5 is partially hollow. The broken line indicates the cavity 6, into which the optical waveguide 1 can be inserted.
Das distale Ende des Lichtwellenleiters ist im gezeigten Beispiel vorbereitet, um in eine aus Glaspulver gesinterte Glashülle 5 eingeschoben zu werden.In the example shown, the distal end of the optical waveguide is prepared to be inserted into a glass envelope 5 sintered from glass powder.
Von der Glasfaser 2 ist das Cladding 3 entfernt worden und auch ein Teil des Schutzmantels 4 ist entfernt. Der so vorbereitete Lichtwellenleiter 1 ist in den Hohlraum 6 bis zum distalen Ende 7 der Glashülle 5 einschiebbar.The cladding 3 has been removed from the glass fiber 2 and part of the protective jacket 4 has also been removed. The optical waveguide 1 prepared in this way can be inserted into the cavity 6 up to the distal end 7 of the glass envelope 5.
Das distale Ende der Glasfaser 2 wird anschließend in einem hier nicht gezeigten Verfahren mit dem distalen Ende 7 der Glashülle 5 verschmolzen.The distal end of the glass fiber 2 is then fused to the distal end 7 of the glass envelope 5 in a method not shown here.
Die Figur 2 zeigt den erfindungsgemäßen Applikator nach dem Verschmelzen von Glasfaser 2 und Glashülle 5. Die partielle Änderung der Materialeigenschaft im Bereich der Verschmelzung führt nun dazu, dass das distale Ende 7 der Glashülle transparent wird und das Laserlicht 10 die Glashülle 5 dort distal verlassen kann.FIG. 2 shows the applicator according to the invention after the glass fiber 2 and the glass envelope 5 have been fused. The partial change in the material properties in the region of the fusion now leads to the distal end 7 of the glass envelope becoming transparent and the laser light 10 being able to leave the glass envelope 5 there distally ,
Das proximale Ende 8 der Glashülle 5 ist mit dem Schutzmantel 4 verklebt. Die Klebestelle ist mit 9 bezeichnet. Der übrige Bereich 10 der Glashülle 5 verbleibt im ursprünglichen, opak Zustand, in diesem Zustand verhält sich der übrige Bereich 10 stark streuend und das Laserlicht wird nach außen abgestrahlt. Dadurch wird das Laserlicht nicht in der Glashülle 5 zurückgeleitet, es tritt an der Klebestelle keine erhöhte Temperatur auf. Dies hat den Vorteil, dass der nur begrenzt temperaturbeständige Kleber sich nicht unter Wärmeeinwirkung auflöst oder weich wird und dadurch keine Klebekraft mehr aufbringt.The proximal end 8 of the glass envelope 5 is glued to the protective jacket 4. The glue point is designated 9. The remaining area 10 of the glass envelope 5 remains in the original, opaque state, in this state the remaining area 10 behaves in a highly scattering manner and the laser light is emitted to the outside. As a result, the laser light is not returned in the glass envelope 5, and there is no increased temperature at the adhesive point. This has the advantage that the adhesive, which is only temperature-resistant to a limited extent, does not dissolve or become soft under the influence of heat and therefore no longer has any adhesive force.
Dies ist insbesondere ein Vorteil, falls der Laserapplikator in einem Lumen des menschlichen Körpers eingesetzt wird. Durch die thermisch nicht belastete Klebestelle 9 ist das Risiko verringert, dass beim Versuch den Applikator aus dem Lumen wieder zu entfernen sich der Lichtleiter von der Glashülle 5 löst und diese Glashülle 5 dann im Lumen verbleibt.This is particularly an advantage if the laser applicator is used in a lumen of the human body. Due to the thermally unloaded glue point 9, the risk is reduced that when trying to remove the applicator from the lumen, the light guide detaches from the glass envelope 5 and this glass envelope 5 then remains in the lumen.
Die Glashulle 5 kann aus sogenanntem „gesintertem" Glas bestehen, welches aufgrund der porösen Struktur das einfallende Licht stark streut. Der Sinterkörper durchläuft mehrere Sinterphasen von Pulverförmig bis homogen transparent, so dass die Streueigenschaften nahezu beliebig eingestellt werden können.The glass envelope 5 can consist of so-called “sintered” glass, which due to the porous structure strongly scatters the incident light. The sintered body passes through several sintering phases from powdery to homogeneously transparent, so that the scattering properties can be set almost arbitrarily.
Bei dem Verschmelzungsvorgang ist das Glasmaterial der Glashülle 5 auch wieder formbar. So lässt sich das distale Ende 6 der Glashülle 5 zum Beispiel abrunden oder auch zu einer Linse mit bestimmten optischen Eigenschaften formen. During the melting process, the glass material of the glass envelope 5 can also be shaped again. For example, the distal end 6 of the glass envelope 5 can be rounded off or can be shaped into a lens with certain optical properties.

Claims

Schutzansprüche protection claims
1.Laserchirurgischer Applikator mit einer Lichtleitfaser mit Glaskern, an deren distalem Ende eine aus einer Glashülse hergestellte Kontaktspitze angeordnet ist, wobei der Glaskern in die Glashülse eingeführt ist und das distale Ende des Glaskernes mit dem distalen Ende der Glashülse zu einer Spitze verbunden ist dadurch gekennzeichnet, dass die Glashülse (5) aus einem das Licht streuenden Material besteht1.Laser surgical applicator with an optical fiber with a glass core, at the distal end of which a contact tip made of a glass sleeve is arranged, the glass core being inserted into the glass sleeve and the distal end of the glass core being connected to the distal end of the glass sleeve to form a tip that the glass sleeve (5) consists of a material that scatters the light
2.Laserchirurgischer Applikator nach Anspruch 1 dadurch gekennzeichnet, dass die Glashülse (5) in dem Teilbereich in welchem sie mit dem distalen Ende des Glaskernes (2) verbunden ist optisch transparent ausgebildet ist2. Laser surgical applicator according to claim 1, characterized in that the glass sleeve (5) is optically transparent in the partial area in which it is connected to the distal end of the glass core (2)
3.Laserchirurgischer Applikator nach Anspruch 1 oder 2 dadurch gekennzeichnet, dass die Glashülse (5) aus gesintertem Material besteht.3.Laser surgical applicator according to claim 1 or 2, characterized in that the glass sleeve (5) consists of sintered material.
4.Laserchirurgischer Applikator nach einem der Ansprüche 1 bis 3 dadurch gekennzeichnet, dass die aus gesintertem Material bestehende Glashülse (5) im distalen Verbindungsbereich mit dem Glaskern (2) verschmolzen ist.4. Laser surgical applicator according to one of claims 1 to 3, characterized in that the glass sleeve (5) consisting of sintered material is fused in the distal connection area with the glass core (2).
5.Laserchirurgischer Applikator nach einem der Ansprüche 1 bis 4 dadurch gekennzeichnet, dass das proximale Ende der Glashülse (5) mit dem Schutzmantel (4) des Lichtleiters (1) verbunden ist.5.Laser surgical applicator according to one of claims 1 to 4, characterized in that the proximal end of the glass sleeve (5) is connected to the protective jacket (4) of the light guide (1).
ό.Laserchirurgischer Applikator nach Anspruch 5 dadurch gekennzeichnet, dass das proximale Ende der Glashülse (5) mit dem Schutzmantel (4) des Lichtleiters (1) verklebt ist. 7Nerfahren zum Herstellen eines laserchirurgischen Applikators mit einer Lichtleitfaser mit Glaskern, an deren distalem Ende eine aus einer Glashülse hergestellte Kontaktspitze angeordnet ist, wobei der Glaskern in die Glashülse eingeführt wird und das distale Ende des Glaskernes mit dem distalen Ende der Glashülse zu einer Spitze verbunden wird, dadurch gekennzeichnet, dass als Material für die Glashülse (5) ein opakes Sinterglas verwendet wird und beim Verbinden des distalen Endes des Glaskerns (2) des Lichtleiters (1) mit der Glashülse (5) das opake Sinterglas der Glashülse (5) in derem distalen Bereich (6) einen transparenten, homogenen Zustand annimmt.ό.Laser surgical applicator according to claim 5, characterized in that the proximal end of the glass sleeve (5) is glued to the protective jacket (4) of the light guide (1). 7 Method for producing a laser surgical applicator with an optical fiber with a glass core, at the distal end of which a contact tip made of a glass sleeve is arranged, the glass core being inserted into the glass sleeve and the distal end of the glass core being connected to the distal end of the glass sleeve to form a tip , characterized in that an opaque sintered glass is used as the material for the glass sleeve (5) and when connecting the distal end of the glass core (2) of the light guide (1) to the glass sleeve (5) the opaque sintered glass of the glass sleeve (5) in the glass sleeve (5) distal region (6) assumes a transparent, homogeneous state.
8Nerfahren nach Anspruch 7 dadurch gekennzeichnet, dass beim Verschmelzen das distale Ende (6) der Glashülse (5) zu einer speziell geformten Spitze verformt wird.8. The method according to claim 7, characterized in that when the fusion occurs, the distal end (6) of the glass sleeve (5) is deformed into a specially shaped tip.
9Nerfahren nach Anspruch 7 oder 8 dadurch gekennzeichnet, dass beim Verschmelzen das distale Ende (6) der Glashülse (5) zu einer Linse mit optischen9.The method according to claim 7 or 8, characterized in that, when fusing, the distal end (6) of the glass sleeve (5) into a lens with optical
Eigenschaften verformt wird. Properties is deformed.
PCT/DE2001/004709 2000-12-18 2001-12-12 Applicator for laser-surgery and a method for the production thereof WO2002049524A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10063029.4 2000-12-18
DE10063029A DE10063029A1 (en) 2000-12-18 2000-12-18 Laser surgical applicator and method for its manufacture

Publications (1)

Publication Number Publication Date
WO2002049524A1 true WO2002049524A1 (en) 2002-06-27

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DE (1) DE10063029A1 (en)
WO (1) WO2002049524A1 (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT201600113597A1 (en) * 2016-11-10 2018-05-10 Elesta S R L LASER THERMO-WELDING DEVICE WITH A HELICAL DIFFUSER AND EQUIPMENT INCLUDING THE DEVICE
IT201600113583A1 (en) * 2016-11-10 2018-05-10 Elesta S R L LASER THERMO-WELDING DEVICE WITH A DIFFUSER CATHETER AND EQUIPMENT INCLUDING THE DEVICE

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Publication number Priority date Publication date Assignee Title
EP3184885A1 (en) * 2015-12-22 2017-06-28 Heraeus Quarzglas GmbH & Co. KG Fibre optic diffusion device and method for producing the same

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DE4137983A1 (en) * 1990-12-19 1992-06-25 Zeiss Carl Fa Laser irradiation application appts. - has light wave conductor with scattering device in closed tubular case, transparent at end to laser
EP0514258A1 (en) * 1991-05-15 1992-11-19 S.L.T. Japan Co, Ltd. Laser light irradiation apparatus
US5304228A (en) * 1990-02-23 1994-04-19 Prince Martin R Method for making optical fiber with atraumatic rounded end for use in laser angioplasty
DE19546447A1 (en) 1994-12-22 1996-06-27 Dornier Medizintechnik Laser surgery applicator for contact vaporisation of tissue
US5997571A (en) * 1997-12-17 1999-12-07 Cardiofocus, Inc. Non-occluding phototherapy probe stabilizers

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Publication number Priority date Publication date Assignee Title
US5304228A (en) * 1990-02-23 1994-04-19 Prince Martin R Method for making optical fiber with atraumatic rounded end for use in laser angioplasty
DE4137983A1 (en) * 1990-12-19 1992-06-25 Zeiss Carl Fa Laser irradiation application appts. - has light wave conductor with scattering device in closed tubular case, transparent at end to laser
EP0514258A1 (en) * 1991-05-15 1992-11-19 S.L.T. Japan Co, Ltd. Laser light irradiation apparatus
DE19546447A1 (en) 1994-12-22 1996-06-27 Dornier Medizintechnik Laser surgery applicator for contact vaporisation of tissue
US5997571A (en) * 1997-12-17 1999-12-07 Cardiofocus, Inc. Non-occluding phototherapy probe stabilizers

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT201600113597A1 (en) * 2016-11-10 2018-05-10 Elesta S R L LASER THERMO-WELDING DEVICE WITH A HELICAL DIFFUSER AND EQUIPMENT INCLUDING THE DEVICE
IT201600113583A1 (en) * 2016-11-10 2018-05-10 Elesta S R L LASER THERMO-WELDING DEVICE WITH A DIFFUSER CATHETER AND EQUIPMENT INCLUDING THE DEVICE
WO2018087015A1 (en) * 2016-11-10 2018-05-17 Elesta S.R.L. Device for laser thermal ablation with a helically shaped diffuser and equipment comprising said device
WO2018087014A1 (en) * 2016-11-10 2018-05-17 Elesta S.R.L. Device for laser thermal ablation with a diffusing catheter and equipment comprising said device
US11135011B2 (en) 2016-11-10 2021-10-05 Elesta S.R.L. Device for laser thermal ablation with a helically shaped diffuser and equipment comprising said device
US11331145B2 (en) 2016-11-10 2022-05-17 Elesta S.R.L. Device for laser thermal ablation with a diffusing catheter and equipment comprising said device

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