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WO2000055193A3 - Nouveaux acides nucleiques et polypeptides - Google Patents

Nouveaux acides nucleiques et polypeptides Download PDF

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Publication number
WO2000055193A3
WO2000055193A3 PCT/US2000/005537 US0005537W WO0055193A3 WO 2000055193 A3 WO2000055193 A3 WO 2000055193A3 US 0005537 W US0005537 W US 0005537W WO 0055193 A3 WO0055193 A3 WO 0055193A3
Authority
WO
WIPO (PCT)
Prior art keywords
dcr6
polypeptides
related protein
cerberus
nucleic acids
Prior art date
Application number
PCT/US2000/005537
Other languages
English (en)
Other versions
WO2000055193A2 (fr
Inventor
Aris N Economides
Original Assignee
Regeneron Pharma
Aris N Economides
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Regeneron Pharma, Aris N Economides filed Critical Regeneron Pharma
Priority to AU35111/00A priority Critical patent/AU3511100A/en
Publication of WO2000055193A2 publication Critical patent/WO2000055193A2/fr
Publication of WO2000055193A3 publication Critical patent/WO2000055193A3/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

L'invention concerne des polypeptides de la protéine 6 liée à DAN/Cerberus (DCR6) et les acides nucléiques associés. Sont compris des homologues naturels de la DCR6 dérivés de plusieurs espèces et des polypeptides comprenant un domaine de DCR6 à activité spécifique. Les polypeptides peuvent être obtenus de manière recombinante à partir de cellules hôtes transformées avec les acides nucléiques. L'invention concerne encore des sondes d'hybridation isolées et des amorces oligonucléotidiques capables de s'hybrider avec les gènes de cette invention, des agents de liaison spécifiques et ainsi que des procédés de production et d'utilisation des compositions.
PCT/US2000/005537 1999-03-12 2000-03-02 Nouveaux acides nucleiques et polypeptides WO2000055193A2 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU35111/00A AU3511100A (en) 1999-03-12 2000-03-02 Novel nucleic acids and polypeptides

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US12411899P 1999-03-12 1999-03-12
US60/124,118 1999-03-12

Publications (2)

Publication Number Publication Date
WO2000055193A2 WO2000055193A2 (fr) 2000-09-21
WO2000055193A3 true WO2000055193A3 (fr) 2001-01-18

Family

ID=22412870

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2000/005537 WO2000055193A2 (fr) 1999-03-12 2000-03-02 Nouveaux acides nucleiques et polypeptides

Country Status (2)

Country Link
AU (1) AU3511100A (fr)
WO (1) WO2000055193A2 (fr)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1857551A3 (fr) * 2000-06-01 2007-11-28 Amgen Inc. Polypeptides à noeud en cystine, molécules 2 masquées et utilisations associées
EP1290169A2 (fr) * 2000-06-01 2003-03-12 Amgen, Inc. Polypeptides a noeud de cystines: molecules "cloaked-2" et leurs utilisations
JP2004520005A (ja) * 2000-06-19 2004-07-08 エフ．ホフマン−ラ　ロシュ　アーゲー オステオレビン遺伝子多型性
US7193069B2 (en) 2002-03-22 2007-03-20 Research Association For Biotechnology Full-length cDNA
CA2567810A1 (fr) 2004-05-27 2005-12-08 Acceleron Pharma Inc. Derives de cerberus/coco et leurs applications
US9045553B2 (en) 2004-05-27 2015-06-02 Acceleron Pharma, Inc. Cerberus/Coco derivatives and uses thereof
WO2008073351A2 (fr) 2006-12-08 2008-06-19 Acceleron Pharma Inc. Utilisations de cerberus, de coco et de leurs dérivés
WO2018115879A1 (fr) 2016-12-21 2018-06-28 Mereo Biopharma 3 Limited Utilisation d'anticorps anti-sclérostine dans le traitement de l'ostéogenèse imparfaite

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000032773A1 (fr) * 1998-11-27 2000-06-08 Darwin Discovery Ltd. Compositions et methodes d'augmentation de la mineralisation de la substance osseuse

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000032773A1 (fr) * 1998-11-27 2000-06-08 Darwin Discovery Ltd. Compositions et methodes d'augmentation de la mineralisation de la substance osseuse

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
BIRREN B. ET AL.: "Homo sapiens chromosome 17, clone HRPC905N1, complete sequence", EMBL DATABASE ENTRY AC003098; ACCESSION NO. AC003098, 14 November 1997 (1997-11-14), XP002146329 *
PEARCE J.J. ET AL.: "A Mouse Cerberus/Dan-Related Gene Family", DEVELOPMENTAL BIOLOGY, vol. 209, no. 1, 1 May 1999 (1999-05-01), pages 98 - 110, XP002146330 *

Also Published As

Publication number Publication date
WO2000055193A2 (fr) 2000-09-21
AU3511100A (en) 2000-10-04

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