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WO1999053069A3 - Proteines de regulation du cycle cellulaire - Google Patents

Proteines de regulation du cycle cellulaire Download PDF

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Publication number
WO1999053069A3
WO1999053069A3 PCT/US1999/007640 US9907640W WO9953069A3 WO 1999053069 A3 WO1999053069 A3 WO 1999053069A3 US 9907640 W US9907640 W US 9907640W WO 9953069 A3 WO9953069 A3 WO 9953069A3
Authority
WO
WIPO (PCT)
Prior art keywords
cell cycle
cycle regulatory
pitslre
cdc2
plants
Prior art date
Application number
PCT/US1999/007640
Other languages
English (en)
Other versions
WO1999053069A2 (fr
Inventor
Theodore M Klein
Layo O Marakinyo
Michele Morgante
Joan T Odell
Stephen O Pember
J Antoni Rafalski
Zude Weng
Original Assignee
Du Pont
Theodore M Klein
Layo O Marakinyo
Michele Morgante
Joan T Odell
Stephen O Pember
J Antoni Rafalski
Zude Weng
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Du Pont, Theodore M Klein, Layo O Marakinyo, Michele Morgante, Joan T Odell, Stephen O Pember, J Antoni Rafalski, Zude Weng filed Critical Du Pont
Priority to EP99916472A priority Critical patent/EP1068335A2/fr
Priority to AU34785/99A priority patent/AU3478599A/en
Publication of WO1999053069A2 publication Critical patent/WO1999053069A2/fr
Publication of WO1999053069A3 publication Critical patent/WO1999053069A3/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C12N9/1205—Phosphotransferases with an alcohol group as acceptor (2.7.1), e.g. protein kinases
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/415—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from plants
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8261—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A40/00—Adaptation technologies in agriculture, forestry, livestock or agroalimentary production
    • Y02A40/10—Adaptation technologies in agriculture, forestry, livestock or agroalimentary production in agriculture
    • Y02A40/146—Genetically Modified [GMO] plants, e.g. transgenic plants

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Cell Biology (AREA)
  • Plant Pathology (AREA)
  • Botany (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Physics & Mathematics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)

Abstract

Cette invention se rapporte à un fragment d'acide nucléique isolé codant une protéine de régulation du cycle cellulaire, ainsi qu'à la construction d'un gène chimérique codant la totalité ou une partie de cette protéine de régulation du cycle cellulaire, selon une orientation sens ou anti-sens, l'expression de ce gène chimérique entraînant la production de niveaux modifiés de cette protéine de régulation du cycle cellulaire dans une cellule hôte transformée.
PCT/US1999/007640 1998-04-09 1999-04-08 Proteines de regulation du cycle cellulaire WO1999053069A2 (fr)

Priority Applications (2)

Application Number Priority Date Filing Date Title
EP99916472A EP1068335A2 (fr) 1998-04-09 1999-04-08 Proteines de regulation du cycle cellulaire
AU34785/99A AU3478599A (en) 1998-04-09 1999-04-08 Cell cycle regulatory proteins

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US8113298P 1998-04-09 1998-04-09
US60/081,132 1998-04-09

Publications (2)

Publication Number Publication Date
WO1999053069A2 WO1999053069A2 (fr) 1999-10-21
WO1999053069A3 true WO1999053069A3 (fr) 2000-03-23

Family

ID=22162293

Family Applications (2)

Application Number Title Priority Date Filing Date
PCT/US1999/007638 WO1999053075A2 (fr) 1998-04-09 1999-04-08 Proteines de regulation du cycle cellulaire cdc-16, dp-1, dp-2 et e2f tirees de plantes
PCT/US1999/007640 WO1999053069A2 (fr) 1998-04-09 1999-04-08 Proteines de regulation du cycle cellulaire

Family Applications Before (1)

Application Number Title Priority Date Filing Date
PCT/US1999/007638 WO1999053075A2 (fr) 1998-04-09 1999-04-08 Proteines de regulation du cycle cellulaire cdc-16, dp-1, dp-2 et e2f tirees de plantes

Country Status (4)

Country Link
EP (2) EP1068335A2 (fr)
AR (2) AR015756A1 (fr)
AU (2) AU3478599A (fr)
WO (2) WO1999053075A2 (fr)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000047614A1 (fr) * 1999-02-12 2000-08-17 Pioneer Hi-Bred International, Inc. Plantes transgeniques a expression modifiee de la proteine dp
AU7781400A (en) * 1999-09-24 2001-04-24 Consejo Superior De Investigaciones Cientificas Wheat dp proteins and uses thereof
HUP0202626A3 (en) * 1999-09-27 2004-09-28 Pioneer Hi Bred Internat Inc J Enhanced stress tolerance in maize via manipulation of cell cycle regulatory genes
GB9923306D0 (en) 1999-10-01 1999-12-08 Isis Innovation Diagnostic and therapeutic epitope, and transgenic plant
GB0212885D0 (en) 2002-06-05 2002-07-17 Isis Innovation Therapeutic epitopes and uses thereof
US10105437B2 (en) 2004-04-28 2018-10-23 Btg International Limited Epitopes related to coeliac disease
CN104056251B (zh) 2004-04-28 2019-09-17 英国技术集团国际有限公司 与腹部疾病有关的表位
US7825293B2 (en) 2004-05-28 2010-11-02 Cropdesign N.V. Plants having improved growth characteristics and a method for making the same

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993010242A1 (fr) * 1991-11-18 1993-05-27 Cold Spring Harbor Laboratory NOUVEAUX GENES HUMAINS cdc25, PRODUITS CODES ET UTILISATIONS
WO1994026888A1 (fr) * 1993-05-19 1994-11-24 The Board Of Trustees Of The Leland Stanford Junior University Inhibition de la proliferation de cellules vasculaires des muscles lisses
WO1996028555A1 (fr) * 1995-03-14 1996-09-19 Thomas Jefferson University Nouvelles proteines humaines semblables a la kinase et dependantes de la cycline et leurs methodes d'application
WO1997047745A1 (fr) * 1996-06-13 1997-12-18 Consejo Superior De Investigaciones Cientificas Proteines vegetales associees au retinoblastome

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0905236A1 (fr) * 1992-10-29 1999-03-31 Medical Research Council Facteur de Transcription DP-1
GB9413327D0 (en) * 1994-07-01 1994-08-24 Medical Res Council Assay for inhibitors of dp-1
GB9610195D0 (en) * 1996-05-15 1996-07-24 Medical Res Council Assay

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993010242A1 (fr) * 1991-11-18 1993-05-27 Cold Spring Harbor Laboratory NOUVEAUX GENES HUMAINS cdc25, PRODUITS CODES ET UTILISATIONS
WO1994026888A1 (fr) * 1993-05-19 1994-11-24 The Board Of Trustees Of The Leland Stanford Junior University Inhibition de la proliferation de cellules vasculaires des muscles lisses
WO1996028555A1 (fr) * 1995-03-14 1996-09-19 Thomas Jefferson University Nouvelles proteines humaines semblables a la kinase et dependantes de la cycline et leurs methodes d'application
WO1997047745A1 (fr) * 1996-06-13 1997-12-18 Consejo Superior De Investigaciones Cientificas Proteines vegetales associees au retinoblastome

Non-Patent Citations (11)

* Cited by examiner, † Cited by third party
Title
COLASANTI J ET AL.: "Isolation and characterization of cDNA clones encoding a functional p34cdc2 homologue from Zea mays", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE USA, vol. 88, April 1991 (1991-04-01), pages 3377 - 3381, XP002113194 *
DATABASE EMEST16 EMBL, Heidelberg, Germany; 31 March 1999 (1999-03-31), SASAKI T: "Rice cDNA from mature leaf", XP002127708 *
DATABASE EMEST9 EMBL, Heidelberg, Germany; 15 August 1997 (1997-08-15), YAMAMOTO K AND SASAKI T: "Rice cDNA from callus", XP002113326 *
DATABASE EMGSS10 EMBL, Heidelberg, Germany; 16 May 1997 (1997-05-16), FENG J ET AL.: "BAC end sequences at ATGC", XP002127707 *
DATABASE EMPLN EMBL, Heidelberg, Germany; 5 February 1999 (1999-02-05), NAKAMURA Y: "Structural analysis of Arabidopsis thaliana chromosome 5", XP002127709 *
DUDITS ET AL: "Cyclin-dependent and calcium-dependent kinase families: response of cell division cycle to hormone and stress signals", PORTLAND PRESS RESEARCH MONOGRAPH, 1996, pages 21 - 45, XP002080506, ISSN: 0964-5845 *
FOBERT P R ET AL.: "Distinct classes of cdc2-related genes are differentially expressed during the cell division cycle in plants", THE PLANT CELL, vol. 8, September 1996 (1996-09-01), pages 1465 - 1476, XP002113324 *
KIDOU S-I ET AL.: "Nucleotide sequence of rice (oryzae sativa L.) cDNA homologous to cdc2 gene", DNA SEQUENCE, vol. 5, 1994, pages 125 - 129, XP002113323 *
MAGYAR Z ET AL.: "Cell cycle phase specificity of putative cyclin-dependent kinase variants in synchronized alfalfa cells", THE PLANT CELL, vol. 9, no. 02-1997, pages 223 - 235, XP002113325 *
MIAO G-H ET AL.: "Two functional soybean genes encoding p34cdc2 protein kinases are regulated by different plant developmental pathways", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE USA, vol. 90, February 1993 (1993-02-01), pages 943 - 947, XP002113195 *
VEYLDER DE L ET AL: "THE ARABIDOPSIS CKS1 AT PROTEIN BINDS THE CYCLIN-DEPENDENT KINASES CDC2AAT AND CDC2BAT", FEBS LETTERS, vol. 412, no. 3, 4 August 1997 (1997-08-04), pages 446 - 452, XP002047992, ISSN: 0014-5793 *

Also Published As

Publication number Publication date
AU3478399A (en) 1999-11-01
WO1999053075A3 (fr) 2000-03-23
AR015756A1 (es) 2001-05-16
EP1068334A2 (fr) 2001-01-17
EP1068335A2 (fr) 2001-01-17
WO1999053075A2 (fr) 1999-10-21
AR015757A1 (es) 2001-05-16
WO1999053069A2 (fr) 1999-10-21
AU3478599A (en) 1999-11-01

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