WO1998047370A1

WO1998047370A1 - Fungicide active substance combinations

Info

Publication number: WO1998047370A1
Application number: PCT/EP1998/001987
Authority: WO
Inventors: Klaus Stenzel; Stefan Dutzmann; Astrid Mauler-Machnik; Lutz Assmann
Original assignee: Bayer Aktiengesellschaft
Priority date: 1997-04-18
Filing date: 1998-04-06
Publication date: 1998-10-29
Also published as: ID24677A; BG103789A; CN1252692A; JP2001505924A; TW385232B; DE19716256A1; TR199902450T2; PL336225A1; CA2286849A1; ZA983235B; AU7522198A; IL131901A0; BR9809763A; EP0975221A1; AU727180B2; NZ500368A; CO5040019A1; KR20010006064A; HUP0002361A3; HUP0002361A2

Abstract

The new active substance combinations of an halogen benzimidazol of formula (I), in which Z stands for chlorine or bromine, and of the groups of active substances (1 to 25) listed in the description have very good fungicide properties.

Description

Fungicidal active ingredient combinations

The present invention relates to new combinations of active ingredients which consist of known halogen-benzimidazoles on the one hand and other known fungicidal active ingredients on the other hand and which are very suitable for combating phytopathogenic fungi.

It is already known that 1- (3,5-dimethyl-isoxazole-4-sulfonyl) -2-bromo-6,6-difluoro- [1,3] -dioxolo- [4,5fj-benzimidazole and 1- ( 3,5-dimethyl-isoxazole-4-sulfonyl) -2-chloro-6,6-di £ luor- [1,3] -dioxolo- [4,5f] -benzimidazole possess fungicidal properties (cf.

WO 97-06171). The effectiveness of these substances is good, but leaves something to be desired in some cases at low application rates.

Furthermore, it is already known that numerous triazole derivatives, aniline derivatives, dicarboximides and other heterocycles can be used to combat fungi (cf. EP-A 0 040 345, DE-A 22 01 063, DE-A 23 24 010, Pesticide Manual, 9th Edition (1991), pages 249 and 827, EP-A 0 382 375 and EP-A 0 515 901). However, the effect of these substances is not always sufficient at low application rates.

Finally, it is also known that l - [(6-chloro-3-pyridinyl) methyl] -N-nitro-2-imidazolidinimine can be used to control animal pests, such as insects (cf. Pesticide Manual, 9th edition (1991), page 491). Fungicidal properties of this substance have not yet been described.

It has now been found that the new active compound combinations consist of a halogenobenzimidazole of the formula

in which

represents chlorine or bromine,

and

(1) a triazole derivative of the formula

in which

X represents chlorine or phenyl, and

- C— - CH-

II I

Y stands for ° or ^0H ,

and or

(2) the triazole derivative of the formula nazole)

and or

(3) an aniline derivative of the formula

in which

R ^{1 represents} hydrogen or methyl,

and or

(4) N- [1 - (4-chloro-ρhenyl) ethyl] -2,2-dichloro-1-ethyl-3-methylcyclopropane-carboxamide of the formula

and or

(5) the zinc propylene 1,2-bis (dithiocarbamidate) of the formula CH, S

I I

- [Zn— S— C— NH— CH ₂ - CH— NH— CS] -

(VI) n> = (Propineb)

and or

(6) at least one thiocarbamate of the formula

Me = Zn or Mn or mixture of Zn and Mn

and or

(7) the aniline derivative of the formula

(Fenhexamide)

and or

(8) the compound of formula

and or

(9) the benzothiadiazole derivative of the formula

and or

(10) the 8-t-butyl-2- (N-ethyl-N-n-propylamino) methyl-1,4-dioxaspiro [5,4] decane of the formula

(Spiroxamine)

and or

(11) the compound of formula

and or (12) the compound of formula

and or

(13) the compound of formula

and or

(14) the cyanoxime derivative of the formula

O O CN

II II I

CH— CH— H— C-NH-CC = STILL ₃ (XV)

(Cymoxanil)

and or

(15) a pyrimidine derivative of the formula

in which

R ^{2 represents} methyl or cyclopropyl,

and or

(16) the aniline derivative of the formula

and or

(17) the morpholine derivative of the formula

(XVIII)

and or (18) the phthalimide derivative of the formula

and or

(19) the phosphorus compound of the formula

and or

(20) the hydroxyethyl triazole derivative of the formula

and or

(21) the 1 - [(6-chloro-3-pyridinyl) methyl] -N-nitro-2-imidazolidinimine of the formula

and or

(22) the oxazolidinedione of the formula

(XXIII)

(Famoxadone)

and or

(23) the benzamide derivative of the formula

and or

(24) a guanidine derivative of the formula

³ R ³

R ³ - N - (CH ₂ ) ₈ - [N - (CH ₂ ) ₈ ] -NH (XXV) π x (2 + m) CH ₃ COOH

in which m stands for integers from 0 to 5 and

R ^{3 represents} hydrogen (17 to 23%) or the rest of the formula

-C = NH | (77 to 83%)

NH.

stands.

and or

(25) the triazole derivative of the formula

have very good fungicidal properties.

Surprisingly, the fungicidal action of the active compound combinations according to the invention is considerably higher than the sum of the actions of the individual active compounds. So there is an unforeseeable, real synergistic effect and not just an addition.

Formula (I) includes

the l- (3,5-dimethyl-isoxazole-4-sulfonyl) -2-bromo-6,6-difluoro- [1,3] -dioxok) - [4,5fj-benzimidazole of the formula

and

the l- (3,5-dimethyl-isoxazole-4-sulfonyl) -2-chloro-6,6-difluoro- [1,3] -dioxolo- [4,5f] -benzimidazole of the formula

The halogen benzimidazoles of the formulas (Ia) and (Ib) are known (cf. WO 97-

06171).

Formula (II) includes the compounds

1- (4-chlorophenoxy) -3,3-dimethyl-1- (1,2,4-triazol-l-yl) -butan-2-one of the formula

1 - (4-chlorophenoxy) -3, 3 -dimethyl-1 - (1, 2,4-triazol-1-yl) -butan-2-ol of the formula

and

1 - (4-phenyl-phenoxy) -3, 3-dimethyl-1 - (1, 2,4-triazol-1-yl) -butan-2-ol of the formula

Formula (IV) comprises the aniline derivatives of the formulas

and

It can be seen from the structural formula for the active ingredient of the formula (V) that the compound has three asymmetrically substituted carbon atoms. The product can therefore be a mixture of different isomers or in the form of a single one

Component. The compounds are particularly preferred N- (R) - [1 - (4-chlorophenyl) ethyl] - (1 S) -2,2-dichloro-1-ethyl-3t-methyl-1 r-cyclopropanecarboxamide of the formula

(S) (R)

and

N- (R) - [1- (4-chlorophenyl) ethyl] - (IR) -2,2-dichloro-l-ethyl-3t-methyl-lr-cyclopropanecarboxamide of the formula

Formula (VII) includes the compounds

(Vlla) Me = Zn (Zineb),

(Vllb) Me = Mn (Maneb) and

(VIIc) mixture of (Vlla) and (Vllb) (Mancozeb).

Formula (XVI) includes the compounds

(XVIa) R ² = CH ₃ (pyrimethanil) and

(XVIb) _{R2 =} (Cyprodinyl) The hydroxyethyl-triazole derivative of the formula (XXI) can be in the "thiono" form of the formula

or in the tautomeric "mercapto" form of the formula

available. For the sake of simplicity, only the "Thiono" shape is listed.

The guanidine derivative of the formula (XXV) is a mixture of substances with the common name guazatine.

The components present in the active compound combinations according to the invention in addition to a halogenobenzimidazole of the formula (I) are also known. The active substances are described in detail in the following publications:

(1) compounds of the formula (II)

DE-A 22 01 063 DE-A 23 24 010 (2) Compound of formula (III) EP-A 0 040 345

(3) compounds of the formula (IV)

Pesticide Manual, 9th. Ed. (1991), pages 249 and 827

(4) Compound of formula (V) and its individual derivatives

EP-A 0 341 475

(5) Compound of Formula (VI)

Pesticide Manual, 9th. Ed. (1991), page 726

(6) Compounds of Formula (VII) Pesticide Manual, 9th. Ed. (1991), pages 529, 531 and 866

(7) Compound of Formula (VIII)

EP-A 0 339 418

(8) Compound of Formula (IX)

EP-A 0 472 996

(9) compound of formula (X)

EP-A 0 313 512

(10) compound of formula (XI)

EP-A 0 281 842

(11) Compound of formula (XII) EP-A 0 382 375

(12) compound of formula (XIII) EP-A 0 515 901

(13) compound of formula (XIV)

DE-A 196 02 095

(14) compound of formula (XV)

Pesticide Manual, 9th. Ed. (1991), page 206

(15) Compounds of the formula (XVI) EP-A 0 270 111

EP-A 0 310 550

(16) compound of the formula (XVΗ)

Pesticide Manual, 9th. Ed. (1991), page 554

(17) compound of formula (XN)

EP-A 0 219 756

(18) Compound of Formula (XIX) Pesticide Manual, 9th. Ed. (1991), page 431

(19) compound of the formula (XX)

Pesticide Manual, 9th. Ed. (1991), page 443

(20) compound of the formula (XXI)

WO 96-16048

(21) Compound of Formula (XXII)

Pesticide Manual, 9th. Ed. (1991), page 491

(22) Compound of the formula (XXm) EP-A 0 393 911 (23) compound of the formula (XXIV)

EP-A 0 600 629

(24) Substance of the formula (XXV)

Pesticide Manual, 9th. Ed. (1991), page 461

(25) compound of the formula (XXVI)

Pesticide Manual, 9th. Ed. (1991), page 654

In addition to an active ingredient of the formula (I), the active ingredient combinations according to the invention contain at least one active ingredient from the compounds of groups (1) to (25). They can also contain other fungicidal admixing components.

If the active compounds are present in the active compound combinations according to the invention in certain weight ratios, the synergistic effect is particularly evident. However, the weight ratios of the active ingredients in the active ingredient combinations can be varied within a relatively wide range. In general, 1 part by weight of active compound of the formula (I)

0.1 to 20 parts by weight, preferably 0.2 to 10 parts by weight of active ingredient from group (1),

0.1 to 20 parts by weight, preferably 0.2 to 10 parts by weight, of active ingredient from group (2),

1 to 150 parts by weight, preferably 1 to 100 parts by weight, of active ingredient from group (3), 0.1 to 10 parts by weight, preferably 0.2 to 5 parts by weight, of active ingredient from group (4),

1 to 150 parts by weight, preferably 5 to 100 parts by weight of active ingredient from group (5),

1 to 150 parts by weight, preferably 5 to 100 parts by weight, of active ingredient from group (6),

0.1 to 50 parts by weight, preferably 1 to 20 parts by weight of active ingredient from the

Group (7),

0.1 to 50 parts by weight, preferably 0.2 to 20 parts by weight, of active ingredient from group (8)

0.02 to 50 parts by weight, preferably 0.1 to 10 parts by weight of active ingredient from group (9),

0.1 to 20 parts by weight, preferably 0.5 to 10 parts by weight of active ingredient from group (10),

0.1 to 50 parts by weight, preferably 0.2 to 20 parts by weight of active ingredient from group (11),

0.1 to 50 parts by weight, preferably 0.2 to 20 parts by weight, of active ingredient from group (12),

0.1 to 50 parts by weight, preferably 0.2 to 20 parts by weight, of active ingredient from group (13), 0.1 to 50 parts by weight, preferably 0.2 to 20 parts by weight, of active ingredient from group (14),

0.2 to 50 parts by weight, preferably 1 to 20 parts by weight, of active ingredient from group (15),

0.1 to 50 parts by weight, preferably 0.2 to 20 parts by weight, of active ingredient from group (16),

0.1 to 50 parts by weight, preferably 0.2 to 20 parts by weight, of active ingredient from group (17),

1 to 150 parts by weight, preferably 5 to 100 parts by weight of active ingredient from the group (18),

0.1 to 150 parts by weight, preferably 1 to 100 parts by weight, of active ingredient from group (19),

0.02 to 50 parts by weight, preferably 0.2 to 10 parts by weight, of active ingredient from group (20),

0.05 to 20 parts by weight, preferably 0.1 to 10 parts by weight of active ingredient from group (21),

0.1 to 50 parts by weight, preferably 0.2 to 20 parts by weight, of active ingredient from group (22),

0.1 to 50 parts by weight, preferably 0.2 to 20 parts by weight, of active ingredient from group (23), 0.02 to 50 parts by weight, preferably 0.04 to 10 parts by weight of active ingredient from group (24) and / or

0.2 to 50 parts by weight, preferably 1 to 20 parts by weight of active ingredient from group (25).

The active compound combinations according to the invention have very good fungicidal properties and can be used to control phytopathogenic fungi, such as Plasmodiophoromycetes, Oomycetes, Chytridiomycetes, Zygomycetes, Ascomycetes, Basidiomycetes, Deuteromycetes, etc.

The active compound combinations according to the invention are particularly suitable for combating cereal diseases, such as Erysiphe, Puccinia and Fusarium, and for combating diseases in viticulture, such as Uncinula, Plasmopara and Botrytis, and also in dicotyledon crops for combating real and

Downy mildew fungi and leaf stain pathogens.

The fact that the active ingredient combinations are well tolerated by plants in the concentrations required to combat plant diseases permits treatment of above-ground parts of plants, of propagation stock and seeds, and of the soil.

The active compound combinations according to the invention can be used for foliar application or as a mordant.

The active compound combinations according to the invention can be converted into the customary formulations, such as solutions, emulsions, suspensions, powders,

Foams, pastes, granules, aerosols, very fine encapsulations in polymeric substances and in coating compositions for seeds, as well as ULV formulations.

These formulations are prepared in a known manner, for example by mixing the active ingredients or combinations of active ingredients with extenders, ie liquid solvents, pressurized liquefied gases and / or solid carriers, optionally using surface-active agents, that is to say emulsifiers and / or dispersants and / or foam-generating agents. If water is used as an extender, organic solvents can, for example, also be used as auxiliary solvents. The following are essentially suitable as liquid solvents: aromatics, such as xylene, toluene or alkylnaphthalenes, chlorinated aromatics or chlorinated aliphatic hydrocarbons, such as chlorobenzenes, chlorethylenes or methylene chloride, aliphatic hydrocarbons, such as cyclohexane or paraffins, for example petroleum fractions, alcohols, such as butanol or Glycol and their ethers and esters, ketones, such as

Acetone, methyl ethyl ketone, methyl isobutyl ketone or cyclohexanone, strongly polar solvents such as dimethylformamide and dimethyl sulfoxide, and water. Liquefied gaseous extenders or carriers mean liquids which are gaseous at normal temperature and pressure, e.g. Aerosol propellants such as butane, propane, nitrogen and carbon dioxide. Possible solid carriers are: e.g. natural rock meals, such as kaolins, clays, talc, chalk, quartz, attapulgite, montmorillonite or diatomaceous earth and synthetic rock meals, such as highly disperse silica, aluminum oxide and silicates. The following are suitable as solid carriers for granules: e.g. broken and fractionated natural rocks such as calcite, marble, pumice, sepiolite, dolomite and synthetic granules from inorganic and organic flours as well as granules from organic material such as sawdust, coconut shells, corn cobs and tobacco stems. Possible emulsifying and / or foaming agents are: e.g. nonionic and anionic emulsifiers such as polyoxyethylene fatty acid esters, polyoxyethylene fatty alcohol ethers, e.g. Alkylaryl polyglycol ether,

Alkyl sulfonates, alkyl sulfates, aryl sulfonates and protein hydrolyzates. Possible dispersants are: e.g. Lignin sulfite liquor and methyl cellulose.

In the formulations, adhesives such as carboxymethyl cellulose, natural and synthetic powdery, granular or latex-shaped polymers can be used such as gum arabic, polyvinyl alcohol, polyvinyl acetate, and natural phospholipids, such as cephalins and lecithins, and synthetic phospholipids. Other additives can be mineral and vegetable oils.

Dyes such as inorganic pigments, e.g. Iron oxide, titanium oxide, ferrocyanin blue and organic dyes such as alizarin, azo and metal phthalocyanine dyes and trace nutrients such as salts of iron, manganese, boron, copper, cobalt, molybdenum and zinc are used.

The formulations generally contain between 0.1 and 95% by weight of active compounds, preferably between 0.5 and 90%.

The active compound combinations according to the invention can be present in the formulations in a mixture with other known active compounds, such as fungicides, insecticides, acaricides and herbicides, and also in mixtures with fertilizers or

Plant growth regulators.

The active compound combinations can be used as such, in the form of their formulations or the use forms prepared therefrom, such as ready-to-use solutions, emulsifiable concentrates, emulsions, suspensions, wettable powders, soluble powders and granules. They are used in the usual way, e.g. by pouring, spraying, spraying, scattering, spreading, dry pickling, wet pickling, wet pickling, slurry pickling or incrusting.

When using the active compound combinations according to the invention, the application rates can be varied within a substantial range, depending on the type of application. In the treatment of parts of plants, the application rates of active compound combination are generally between 0.1 and 10,000 g / ha, preferably between 10 and 1,000 g / ha. In the case of seed treatment, the amount of active ingredient combination used is generally between 0.001 and 50 g per kilo grams of seed, preferably between 0.01 and 10 g per kilogram of seed. In the treatment of the soil, the application rates of active compound combination are generally between 0.1 and 10,000 g / ha, preferably between 1 and 5,000 g / ha.

The good fungicidal activity of the active compound combinations according to the invention can be seen from the examples below. While the individual active ingredients have weaknesses in their fungicidal action, the combinations show an action that goes beyond a simple summation of action.

Fungicides always have a synergistic effect if the fungicidal activity of the active ingredient combinations is greater than the sum of the effects of the individually applied active ingredients.

The expected effect for a given combination of two active ingredients can, according to S.R. Colby ("Calculating Synergistic and Antagonistic Responses of Herbicide Combinations", Weeds J_5 (1967), 20-22) can be calculated as follows:

If

X means the efficiency when using the active ingredient A in an application rate of m g / ha,

Y means the efficiency when using the active ingredient B in an application rate of n g / ha and

E means the efficiency when using active ingredients A and B in application rates of m and n g / ha,

then X - Y

E = X + Y -

100

The efficiency is determined in%. It means 0% an efficiency which corresponds to that of the control, while an efficiency of 100% means that no infection is observed.

If the actual fungicidal activity is greater than calculated, the combination of the combination is superadditive, i.e. there is a synergistic effect. In this case, the actually observed efficiency must be greater than the value for the expected efficiency (E) calculated from the above formula.

The invention is illustrated by the following examples.

example 1

Phytophthora test (tomato) / protective

Solvent: 47 parts by weight of acetone

Emulsifier: 3 parts by weight of alkylaryl polyglycol ether

To produce a suitable preparation of active compound, 1 part by weight of active compound or combination of active compounds is mixed with the stated amounts of solvent and emulsifier and the concentrate is diluted with water to the desired concentration, or a commercial formulation of active compound or combination of active compounds is diluted with water to the desired concentration.

To test for protective efficacy, young plants are sprayed with the preparation of active compound in the application rate given. After the spray coating has dried on, the plants are inoculated with an aqueous spore suspension of Phytophthora infestans. The plants are then placed in an incubation cabin at approx. 20 ° C and 100% relative humidity.

Evaluation is carried out 3 days after the inoculation. 0% means an efficiency that corresponds to that of the control, while an efficiency of 100% means that no infection is observed.

Active substances, application rates and test results are shown in the following table. Table 1

Phytophthora test (tomato) / protective

Table 1 (continued)

Phytophthora test (tomato) / protective

Table 1 (continued)

Phytophthora test (tomato) / protective

Table 1 (continued)

Phytophthora test (tomato) / protective

Table 1 (continued)

Phytophthora test (tomato) / protective

Table 1 (continued)

Phytophthora test (tomato) / protective

Table 1 (continued)

Phytophthora test (tomato) / protective

Table 1 (continued)

Phytophthora test (tomato) / protective

Table 1 (continued)

Phytophthora test (tomato) / protective

Table 1 (continued)

Phytophthora test (tomato) / protective

Table 1 (continued)

Phytophthora test (tomato) / protective

Table 1 (continued)

Phytophthora test (tomato) / protective

Table 1 (continued)

Phytophthora test (tomato) / protective

Table 1 (continued)

Phytophthora test (tomato) / protective

Table 1 (continued)

Phytophthora test (tomato) / protective

calc. = efficiency calculated according to the Colby formula

Example 2

Fusarium nivale test (triticale) / seed treatment

The active ingredients are used as dry mordants. They are prepared by stripping the respective active ingredient or the combination of active impacts with stone powder to form a fine powder mixture which ensures an even distribution on the seed surface.

For the dressing, the infected seed is shaken with the dressing in a sealed glass bottle for 3 minutes.

The triticale is sown with 2 x 100 seeds 1 cm deep in a standard soil and cultivated in a greenhouse at a temperature of approx. 10 ° C and a relative humidity of approx. 95% in seed boxes that are exposed to light for 15 hours a day.

Approximately The plants are evaluated for symptoms 3 weeks after sowing. 0% means an efficiency that corresponds to that of the control, while an efficiency of 100% means that no infection is observed.

Active substances, application rates and test results are shown in the following table.

Table 2

Fusarium nivale test (triticale) / seed treatment

Example 3

Pythium sp. Test (pea) / seed treatment

The active ingredients are used as dry mordants. They are prepared by stripping the respective active ingredient or combination of active ingredients with rock flour to form a fine powder mixture which ensures an even distribution on the seed surface.

The seeds are sown with 2 x 50 seeds 2 cm deep in a Pythium sp. naturally infected compost and cultivate it in the greenhouse at a temperature of around 20 ° C in seed boxes that are exposed to the light for 15 hours a day.

The evaluation is carried out after 14 days. 0% means an efficiency that corresponds to that of the control, while an efficiency of 100% means that no infection is observed.

Table 3

Pythium sp. Test (pea) / seed treatment

Claims

claims

1. Fungicidal compositions, characterized by a content of an active ingredient combination consisting of

a halogen benzimidazole of the formula

in which

Z represents chlorine or bromine,

and

(1) a triazole derivative of the formula

in which

X represents chlorine or phenyl, and - C— - CH-

II I

Y stands for ° or ^OH ,

and or

(2) the triazole derivative of the formula

nazole)

and or

(3) an aniline derivative of the formula

in which

R ^{1 represents} hydrogen or methyl,

and or

(4) N- [1 - (4-chlorophenyl) ethyl] -2,2-dichloro-1-ethyl-3-methyl-cyclopropane-carboxamide of the formula

and or

(5) the zinc propylene 1,2-bis (dithiocarbamidate) of the formula

- [Zn— S— C— NH— CH ₂ - CH - NH - CS] -

(VI) n> = 1 (propineb)

and or

(6) at least one thiocarbamate of the formula

Me = Zn or Mn or mixture of Zn and Mn

and or

(7) the aniline derivative of the formula

(Fenhexamide)

and or

(8) the compound of formula

and or

(9) the benzothiadiazole derivative of the formula

and or

(Spiroxamine) and or

(11) the compound of formula

and or

(12) the compound of formula

and or

(13) the compound of formula

and or (14) the cyanoxime derivative of the formula

0 o CN

II II I

CH— CH— NH— C-NH-CC = STILL ₃ (XV)

(Cymoxanil)

and or

(15) a pyrimidine derivative of the formula

in which

R ^{2 represents} methyl or cyclopropyl,

and or

(16) the aniline derivative of the formula

and or (17) the morpholine derivative of the formula

(XVIII)

and or

(18) the phthalimide derivative of the formula

and or

(19) the phosphorus compound of the formula

and or

(20) the hydroxyethyl triazole derivative of the formula

and or

(21) the l - [(6-CWor-3-pyridinyl) methyl] -N-mtro-2-irddazolidinimine of the formula

^{Cl NN} - ^N ° ₂ (imidacloprid)

and or

(22) the oxazolidinedione of the formula

(XXIII)

(Famoxadone)

and or

(23) the benzamide derivative of the formula

and or

(24) a guanidine derivative of the formula

³ R ³

R— N— (CH ₂ ) ₈ - [N— (CH ₂ ) _Θ ] -NH (XXV) π x (2 + m) CH ₃ COOH in which

m stands for integers from 0 to 5 and

R ^{3 represents} hydrogen (17 to 23%) or the rest of the formula

-C = NH | (77 to 83%)

NH,

stands,

and or

(25) the triazole derivative of the formula

2. Composition according to claim 1, characterized in that in the active ingredient combinations, the weight ratio of active ingredient of formula (I)

Active ingredient of group (1) is between 1: 0.1 and 1:20, active ingredient of group (2) is between 1: 0.1 and 1:20, active ingredient of group (3) is between 1: 1 and 1: 150 is, active ingredient of group (4) is between 1: 0.1 and 1:10, active ingredient of group (5) is between 1: 1 and 1: 150, active ingredient of group (6) is between 1: 1 and 1: 150 is, active ingredient of group (7) is between 1: 0.1 and 1:50, active ingredient of group (8) is between 1: 0.1 and 1:50, active ingredient of group (9) is between 1: 0.02 and 1:50, active ingredient of group (10) is between 1: 0.1 and 1:20,

■ active ingredient of group (11) is between 1: 0.1 and 1:50, • active ingredient of group (12) is between 1: 0.1 and 1:50,

Active ingredient of group (13) is between 1: 0.1 and 1:50,

Active ingredient of group (14) is between 1: 0.1 and 1:50,

Active ingredient of group (15) is between 1: 0.2 and 1:50,

Active ingredient of group (16) is between 1: 0.1 and 1:50,

Active ingredient of group (17) is between 1: 0.1 and 1:50,

Active ingredient of group (18) is between 1: 1 and 1: 150,

Active ingredient of group (19) is between 1: 0.1 and 1: 150,

Active ingredient of group (20) is between 1: 0.02 and 1:50,

Active ingredient of group (21) is between 1: 0.05 and 1:20,

Active ingredient of group (22) is between 1: 0.1 and 1:50, Active ingredient of group (23) is between 1: 0.1 and 1:50,

- Active ingredient of group (24) is between 1: 0.02 and 1: 50 and

- Active ingredient of group (25) is between 1: 0.2 and 1:50.

3. Process for combating fungi, characterized in that active ingredient combinations according to claim 1 are applied to the fungi and / or their habitat.

4. Use of drug combinations according to claim 1 for combating fungi.

5. A process for the preparation of fungicidal agents, characterized in that active ingredient combinations according to claim 1 are mixed with extenders and / or surface-active substances.