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WO1997026941A1 - Calotte d'etancheite double - Google Patents

Calotte d'etancheite double Download PDF

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Publication number
WO1997026941A1
WO1997026941A1 PCT/SE1997/000095 SE9700095W WO9726941A1 WO 1997026941 A1 WO1997026941 A1 WO 1997026941A1 SE 9700095 W SE9700095 W SE 9700095W WO 9726941 A1 WO9726941 A1 WO 9726941A1
Authority
WO
WIPO (PCT)
Prior art keywords
cap
port
seal
sealing
dialyzer
Prior art date
Application number
PCT/SE1997/000095
Other languages
English (en)
Inventor
Helmut Hildwein
Günther Maier
Georg Mayer
Gerhard Riede
Jean-Claude Riquier
Gerald Ritzau
Uwe Schwerer
Josef Volm
Wolfgang Wehmeyer
Original Assignee
Gambro Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gambro Ab filed Critical Gambro Ab
Publication of WO1997026941A1 publication Critical patent/WO1997026941A1/fr

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D41/00—Caps, e.g. crown caps or crown seals, i.e. members having parts arranged for engagement with the external periphery of a neck or wall defining a pouring opening or discharge aperture; Protective cap-like covers for closure members, e.g. decorative covers of metal foil or paper
    • B65D41/32—Caps or cap-like covers with lines of weakness, tearing-strips, tags, or like opening or removal devices, e.g. to facilitate formation of pouring openings
    • B65D41/46—Snap-on caps or cap-like covers
    • B65D41/48—Snap-on caps or cap-like covers non-metallic, e.g. made of paper or plastics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M39/00—Tubes, tube connectors, tube couplings, valves, access sites or the like, specially adapted for medical use
    • A61M39/20—Closure caps or plugs for connectors or open ends of tubes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D41/00—Caps, e.g. crown caps or crown seals, i.e. members having parts arranged for engagement with the external periphery of a neck or wall defining a pouring opening or discharge aperture; Protective cap-like covers for closure members, e.g. decorative covers of metal foil or paper
    • B65D41/32—Caps or cap-like covers with lines of weakness, tearing-strips, tags, or like opening or removal devices, e.g. to facilitate formation of pouring openings
    • B65D41/34—Threaded or like caps or cap-like covers provided with tamper elements formed in, or attached to, the closure skirt
    • B65D41/3404—Threaded or like caps or cap-like covers provided with tamper elements formed in, or attached to, the closure skirt with ratchet-and-pawl mechanism between the container and the closure skirt or the tamper element
    • B65D41/3409—Threaded or like caps or cap-like covers provided with tamper elements formed in, or attached to, the closure skirt with ratchet-and-pawl mechanism between the container and the closure skirt or the tamper element the tamper element being integrally connected to the closure by means of bridges
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D51/00—Closures not otherwise provided for
    • B65D51/16—Closures not otherwise provided for with means for venting air or gas
    • B65D51/1605—Closures not otherwise provided for with means for venting air or gas whereby the interior of the container is maintained in permanent gaseous communication with the exterior
    • B65D51/1616—Closures not otherwise provided for with means for venting air or gas whereby the interior of the container is maintained in permanent gaseous communication with the exterior by means of a filter
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D51/00—Closures not otherwise provided for
    • B65D51/18—Arrangements of closures with protective outer cap-like covers or of two or more co-operating closures
    • B65D51/20—Caps, lids, or covers co-operating with an inner closure arranged to be opened by piercing, cutting, or tearing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
    • A61M1/16—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2209/00—Ancillary equipment
    • A61M2209/06—Packaging for specific medical equipment
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D2251/00—Details relating to container closures
    • B65D2251/0003—Two or more closures
    • B65D2251/0006—Upper closure
    • B65D2251/0025—Upper closure of the 47-type
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D2251/00—Details relating to container closures
    • B65D2251/0003—Two or more closures
    • B65D2251/0068—Lower closure
    • B65D2251/0093—Membrane
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D2401/00—Tamper-indicating means
    • B65D2401/15—Tearable part of the closure
    • B65D2401/20—Frangible elements completely enclosed in closure skirt
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D2577/00—Packages formed by enclosing articles or materials in preformed containers, e.g. boxes, cartons, sacks, bags
    • B65D2577/10—Container closures formed after filling
    • B65D2577/20—Container closures formed after filling by applying separate lids or covers
    • B65D2577/2041—Pull tabs
    • B65D2577/205—Pull tabs integral with the closure

Definitions

  • the present invention relates to a double seal cap for a medical device, especially for a dialyzer, for protecting connection ports or other connections of the device from contamination after a sterilization process.
  • the dialyzer After the manufacturing of a dialyzer, a blood line system or other similar medical device, the dialyzer is packed in a protective wrapping, such as a plastic bag and/or a paper wrapping, and the entire pack is exposed to a sterilization agent, such as ethylene oxide (ETO) , steam, plasma sterilisation or similar.
  • a sterilization agent such as ethylene oxide (ETO) , steam, plasma sterilisation or similar.
  • ETO ethylene oxide
  • steam plasma sterilisation
  • connection ports are already provided with an inner seal or sterility barrier, which forms a barrier against microbiological contamination.
  • the inner seal is usually attached directly to the connection port of the dialyzer.
  • the object of the present invention is to provide an alternative for the commonly used wrapping, which is more easily recycled and means a cut down on material expenditure. Especially the volume of the waste wrapping material is reduced by a factor of 10 or more. According to the present invention, it is noted that a major portion of the dialyzer does not need any protection, such as the outer peripheral surface. It is only the connection ports and the surrounding area which actually need protection against contami ⁇ nation.
  • a double seal cap is provided, which is intended to be placed on the connection ports or similar area to be protected of a dialyzers, blood line systems or similar medical devices.
  • the double seal cap according to the invention has the features defined in the following claims.
  • Fig. 1 is a perspective view of a connection port at the blood side of a dialyzer to be provided with an inner seal and adapted to be provided with a cap according to the invention.
  • Fig. 2 is a cross-sectional view of a double seal cap according to the invention intended to be placed on the port shown in Fig. 1.
  • Fig. 3 is a partially cut perspective view of the cap shown in Fig. 2.
  • Fig. 4 is a perspective view of the cap shown in Fig. 3 with a tongue in an opened position.
  • Fig. 5 is a partially cut perspective view of an alternative cap adapted on a corresponding connection port.
  • Fig. 6 is a partially cut perspective view of another alternative cap.
  • Fig. 7 is a partially cut perspective view of another cap design according to the invention comprising a bellow portion.
  • Fig. 8 is a cross-sectional view of another embodiment of the invention.
  • Fig. 9 is a perspective view of a port design mating to the cap shown in Fig. 8.
  • Fig. 10 is a partially cut perspective view of another cap and port design according to the invention and adapted for the dialysate solution side of a dialyzer.
  • Fig. 11 is a partially cut perspective view of still another embodiment of the cap according to the invention, adapted for a dialysate connector.
  • Fig. 12 is a partially cut perspective view of a port provided with another inner seal and a cap according to the invention.
  • Fig. 1 is a perspective view of a connection port 1 arranged in the end portion of a dialyzer 2, such as one of two blood connection ports.
  • the dialyzer is also provided with two connection ports for dialysate solution, usually at the side surface of the dialyzer, and the invention is applicable also for said dialysate ports.
  • the dialyzer housing can be made of different materials such as PC, SAN, ABS, PP, PE or other plastics material.
  • the port shown in Fig. 1 is provided with an inner luer male connector 3 intended for connection with a blood line to be attached to the dialyzer.
  • the connector is surrounded by a sleeve 4, which is provided with interior threads for interaction with a female luer connector of the blood line, which is provided with outside threads.
  • the outer surface of said sleeve 4 is provided with some formations specific for the present invention, while the outer surface of the sleeve normally is smooth, i.e. without any formations.
  • the height of the sleeve is the same or slightly higher than the inner male luer connector 3, so that the sleeve exposes a rim portion 5.
  • An inner seal film 6 is attached to said rim portion 5, as shown by arrows 7 in Fig. 1.
  • the seal film 6 is attached to the rim portion by gluing, ultrasonic welding, heat sealing or another technique resulting in a connection which canpurposeee sterility after termination of the sterilization process.
  • the inner seal film is made of a membrane material, such as GORETEX ® , sterile paper, TYVEK ® , (spunbonded olefin from DuPont) etc. or another appropriate membrane material, which is permeable to the sterilization agent used, such as ETO or steam etc.
  • a ring portion 8 of the seal film can be coated with a different compatible material, such as a thermosensitive glue.
  • a different compatible material such as a thermosensitive glue.
  • at least the inner surface area of the seal film 6 must be permeable to the sterilization agent so that it can penetrate the inner portion of the device.
  • sealing film materials can also be used, provided it can be fixed to the sleeve rim portion 5 and still be permeable to the sterilizing agent.
  • One such material is a film provided with several, equally spaced dots of glue material so that the glue spots form a continuous seal at the rim portion but leave free the surface for passage of the sterilizing agent.
  • connection between the port material and the inner seal film must be performed in a way that the seal film can be peeled off before use.
  • the seal film is provided with a tear tab 9 as shown.
  • the inner seal film can be replaced by screw caps interacting with the inner screw threads of the sleeve and providing a sterile inner protection for the luer connector, compare below in connection with Fig. 12.
  • dialyzer it is not sufficient to have an inner seal film as described above, but usually the dialyzer is placed in a plastic wrapping providing a contamination barrier or outer seal.
  • a double seal cap as the outer seal, which basically has three functions:
  • a first embodiment of the double seal cap according to the invention is shown in Fig. 2.
  • the cap has generally a comple- mentary shape to the outer surface of the port sleeve 4 shown in Fig. 1.
  • the outer sleeve surface is provided with a screw threaded portion 10, a sealing surface 11 and an indentation portion 12.
  • the cap 20 is provided with a screw threaded portion 21 having inner threads, a sealing portion 22 having a sealing ridge 24 and a teeth portion 23.
  • Said sealing ridge 24 forms together with the sealing surface 11 a first seal of the cap.
  • the cap is provided with a sterility membrane 25 attached to the upper end of the cap and forming a second seal of the cap.
  • the cap 20 is intended to be placed upon the connection port 1 so that the threads 10 and 21 interact to keep the cap in place upon the port.
  • the sealing ridge 24 has an internal diameter, which is slightly smaller than the outer diameter of the sealing surface 11 so that a hermetic seal is formed upon placement of the cap on the port sleeve.
  • the sealing surface 11 is preferably cylindrical but can also be slightly conical so that the seal is safely obtained and the material in the ridge is slightly deformed upon securing the cap on the sleeve.
  • the teeth portion 23 has one internal tooth 26 (or several teeth) for interaction with serration and indentations in the indentation portion 12 of the sleeve.
  • the tooth 26 prevents unintentional or accidental withdrawal of the cap.
  • the tooth 26 is provided on a tongue 27 being attached to the teeth portion 23 by two bridge portions 28, forming a hinge, and a breakable portion 29.
  • the breakable portion 29 is ruptured by hand force and the tongue 27 is withdrawn as shown in Fig. 4, whereupon the cap can be removed.
  • the tongue is provided with a handgrip 30, shown by dotted lines in Fig. 3 for facilitating the intentional removal of the tongue 27.
  • the teeth portion 23 ends with a rim portion 31, which interacts with the upper surface of the dialyzer 2 to form an end position for the cap when tightened to the port.
  • a rim portion 31 which interacts with the upper surface of the dialyzer 2 to form an end position for the cap when tightened to the port.
  • end position can be defined by a shoulder portion 32 above the screw portion 21, which cooperates with the rim portion 5 of the sleeve and the inner seal film 6, 8 attached to said rim portion 5.
  • the cap is provided with a dome portion 33, extending the cap above the rim portion 5 of the sleeve.
  • the dome portion 33 comprises a seal membrane 25 attached inside the dome and covering the upper portion of the cap 20.
  • the dome portion is provided with an inner annular surface 34 forming a connection surface for the seal membrane 25.
  • the seal membrane is at least at the central portion thereof made of a material which is permeable for the sterilization agent used. A suitable material is paper, TYVEK ® etc.
  • the seal membrane 25 is fixed inside the dome portion 33 at the annular surface 34 by gluing, ultrasonic welding, heat sealing etc.
  • the seal membrane 25 is placed at a distance above the tear off seal film 6, so that there is no contact between the two sealing materials.
  • the seal membrane 25 is connected to the outside of the cap via several slits 35 covered by a cap top 36 as is clearly shown in Fig. 3.
  • a sterilizing agent such as steam or ETO can enter the cap through said slits 35 and pass the membrane 25 and the film 6 and enter the inside of the medical device for sterilizing purpose.
  • Seal membrane 25 prevents bacteria and other contaminating particles from entering inside the cap via said slits 35.
  • Sealing ridge 24 prevents bacteria and particles from entering the interior of the cap from the other end of the cap, i.e. via the exterior surface of the sleeve.
  • cap 20 provides a sealed area between ridge 24 and seal membrane 25, which is free from contamination from the outside.
  • Tongue 27 forms an integrity indication means informing the user that the cap has not been tampered during the storage and transport time between the manufacturing and the final use.
  • the tongue is removed as shown in Fig. 4 and the cap is taken off.
  • the seal film 6 is peeled off by means of the tear tab 9, and the dialyzer is ready for use and connection to a blood tube.
  • the protective cap can be collected and returned to the manufacturer for reuse.
  • the only packaging material to be discarded is the material in the tear off seal film 6.
  • the outer surface of the sleeve has a certain design in order to adapt the sleeve to use according to the present invention and as shown in Fig. 1.
  • Fig. 5 there is shown another design of the outer surface of the sleeve which can be used according to the present invention.
  • the sleeve 40 according to Fig. 5 is provided with a generally cylindrical surface having a downwards facing shoulder 42.
  • the double seal cap according to this embodiment lacks the screw thread portion and is provided with a break-off ring portion 43 engaging below said shoulder 42.
  • the break-off ring portion 43 is connected to the remaining cap by a peripheral web portion 44.
  • the break-off ring portion 43 is severed from the cap by pulling a tear tab 45, whereby the web portion 44 breaks around the periphery and frees the remaining cap.
  • the cap is provided with a ridge portion 46 which cooperates with surface 41 of the sleeve to form a contamination seal as in the embodiment shown in Fig. 2. In all other respects, the operation is similar to the embodiment shown in Fig. 2.
  • Fig. 6 shows another alternative method of attaching the double seal cap to the dialyzer 2.
  • the cap is fixed by means of a "drop" 47 of sealing wax or a glued paper seal. This seal must be destroyed in order to remove the cap, which forms the integrity control.
  • This double seal cap can be used on an ordinary dialyzer without requiring any modification of the outer surface of the sleeve of the dialyzer port.
  • Fig. 7 The dome portion is provided with a bellow portion 48 being resilient both in the axial direction as well as in the side direction. In this embodiment, the inner seal film is well protected.
  • the threaded portion 21 and the sealing portion 22 are interchanged with each other as shown in Fig. 8.
  • the outer surface of the sleeve is correspondingly shaped as shown in Fig. 9.
  • the distance between the inner seal film 6 and the outer seal membrane 25 is made larger.
  • the sealing surface 50 of the sleeve is provided with a conical portion 51 for interaction with the internal sealing ridge 52 of the cap.
  • Fig. 10 shows an embodiment of the double seal cap according to the invention adapted to be used on a dialyzer port intended for dialysate solution provided on the side surface of a cylindrical hollow fiber dialysator.
  • the design and operation is very similar to the embodiment shown in Figs. 8 and 9, but the threaded portion is longer and adapted to the screw threads often found on such ports.
  • the port outer surface is provided with several teeth 54, 55, two of which are shown in Fig. 10.
  • Such teeth interact with several teeth 56, 57 on the interior surface of the cap at a tear off band 58 attached to the cap via a rupturable web 58.
  • the operation of this embodiment should be obvious to the reader.
  • FIG. 10 shows an embodiment of the double seal cap according to the invention adapted to be used on a dialyzer port intended for dialysate solution provided on the side surface of a cylindrical hollow fiber dialysator.
  • the design and operation is very similar to the embodiment shown in Figs. 8 and 9, but the threaded portion
  • the cap according to the invention is provided with a snapp fastener ring 59 which engages below a shoulder 60 of the sleeve outer surface 61.
  • a weakened rib 62 breaks between the fastener ring 59 and the remaining cap and forms an integrity indication.
  • Fig. 11 corresponds to the embodiment of Fig. 10.
  • Fig. 12 shows an embodiment of the cap according to the invention, and substantially as shown in Fig. 8, attached to a sleeve port provided with a removeable inner seal member 63.
  • Said member 63 includes an outer thread 64, engaging an inner thread 65 of the sleeve normally used by the Luer connector of the blood line to be connected to the port.
  • the seal member 63 is provided with a sealing film 66 at its top, permitting passage of the sterilizing agent.

Landscapes

  • Engineering & Computer Science (AREA)
  • Mechanical Engineering (AREA)
  • Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pulmonology (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • External Artificial Organs (AREA)
  • Closures For Containers (AREA)

Abstract

L'invention porte sur une calotte d'étanchéité double destinée à protéger les orifices de raccordement d'un dispositif médical, un appareil à dialyse par exemple. Cette calotte est pourvue d'un filetage (21) coopérant avec le filetage (10) de l'orifice. Une partie d'étanchéité (22) de la calotte, ayant la forme d'un segment de nervure (24), coopère avec une surface d'étanchéité (11), quasiment cylindrique, de l'orifice, pour constituer une première fermeture hermétique. La partie supérieure de la calotte est recouverte d'une membrane (25) perméable à un agent stérilisant (oxyde d'éthylène ou vapeur) et constituant une seconde fermeture hermétique. Un équipement de contrôle de l'intégrité du dispositif (27) situé dans la partie inférieure de la calotte signale toute manipulation non autorisée de celle-ci durant le transport ou le stockage.
PCT/SE1997/000095 1996-01-22 1997-01-22 Calotte d'etancheite double WO1997026941A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE9600215A SE508379C2 (sv) 1996-01-22 1996-01-22 Lock med dubbel tätning
SE9600215-9 1996-01-22

Publications (1)

Publication Number Publication Date
WO1997026941A1 true WO1997026941A1 (fr) 1997-07-31

Family

ID=20401097

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/SE1997/000095 WO1997026941A1 (fr) 1996-01-22 1997-01-22 Calotte d'etancheite double

Country Status (2)

Country Link
SE (1) SE508379C2 (fr)
WO (1) WO1997026941A1 (fr)

Cited By (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0899204A1 (fr) * 1997-08-26 1999-03-03 Mob Bouchon a bande d'inviolabilité pour flacon à col de grand diametre
EP1375372A2 (fr) * 2002-06-21 2004-01-02 Weener Plastik GmbH & Co. KG Fermeture munie d'un dispositif verseur
WO2005032964A2 (fr) * 2003-10-03 2005-04-14 Bristol Myers Squibb Company Recipient et systeme d'etancheification
US6948631B2 (en) 2004-01-08 2005-09-27 3088081 Canada Inc. Controllable tamper proof closure for a vial
KR100735643B1 (ko) * 2000-04-12 2007-07-06 알루미늄 뻬쉬니 내화재 전구체 페이스트
EP1847469A2 (fr) 2006-04-12 2007-10-24 Terxo AG Fermeture de récipient doté d'un indicateur d'intégrité
EP2347827A1 (fr) * 2004-08-30 2011-07-27 Bracco Diagnostic Inc. Recipients ameliores pour produits pharmaceutiques, utilises en particulier dans des generateurs de radioisotopes
US8584876B2 (en) 2007-07-05 2013-11-19 Kraft Foods Group Brands Llc Food containers adapted for accommodating pressure changes using skip seals and methods of manufacture
DE102016116098A1 (de) 2016-08-30 2018-03-01 B. Braun Avitum Ag Verschlusskappe für einen kartuschenförmigen Behälter

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA3158095A1 (fr) * 2019-11-11 2021-05-20 John Grant Capuchons et couvercles a usage unique pour dispositifs d'acces vasculaire, et kits et procedes pour utiliser ceux-ci

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3923179A (en) * 1973-03-07 1975-12-02 American Hospital Supply Corp Medical liquid container with tactile sterility indicator and method of testing container
WO1994028855A1 (fr) * 1993-06-10 1994-12-22 Baxter International Inc. Dispositif de protection ameliore pour orifice d'acces et recipients le comprenant

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3923179A (en) * 1973-03-07 1975-12-02 American Hospital Supply Corp Medical liquid container with tactile sterility indicator and method of testing container
WO1994028855A1 (fr) * 1993-06-10 1994-12-22 Baxter International Inc. Dispositif de protection ameliore pour orifice d'acces et recipients le comprenant

Cited By (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2767792A1 (fr) * 1997-08-26 1999-03-05 Nord Est Dev Bouchon a bande d'inviolabilite pour flacon a col de grand diametre
EP0899204A1 (fr) * 1997-08-26 1999-03-03 Mob Bouchon a bande d'inviolabilité pour flacon à col de grand diametre
KR100735643B1 (ko) * 2000-04-12 2007-07-06 알루미늄 뻬쉬니 내화재 전구체 페이스트
EP1375372A2 (fr) * 2002-06-21 2004-01-02 Weener Plastik GmbH & Co. KG Fermeture munie d'un dispositif verseur
EP1375372A3 (fr) * 2002-06-21 2008-05-28 Weener Plastik GmbH & Co. KG Fermeture munie d'un dispositif verseur
WO2005032964A3 (fr) * 2003-10-03 2005-06-02 Bristol Myers Squibb Co Recipient et systeme d'etancheification
WO2005032964A2 (fr) * 2003-10-03 2005-04-14 Bristol Myers Squibb Company Recipient et systeme d'etancheification
US6948631B2 (en) 2004-01-08 2005-09-27 3088081 Canada Inc. Controllable tamper proof closure for a vial
EP2347827A1 (fr) * 2004-08-30 2011-07-27 Bracco Diagnostic Inc. Recipients ameliores pour produits pharmaceutiques, utilises en particulier dans des generateurs de radioisotopes
US8058632B2 (en) 2004-08-30 2011-11-15 Bracco Diagnostics, Inc. Containers for pharmaceuticals, particularly for use in radioisotope generators
US9562640B2 (en) 2004-08-30 2017-02-07 Bracco Diagnostics Inc. Containers for pharmaceuticals, particularly for use in radioisotope generators
EP1847469A2 (fr) 2006-04-12 2007-10-24 Terxo AG Fermeture de récipient doté d'un indicateur d'intégrité
EP1847469A3 (fr) * 2006-04-12 2009-01-28 Terxo AG Fermeture de récipient doté d'un indicateur d'intégrité
US8584876B2 (en) 2007-07-05 2013-11-19 Kraft Foods Group Brands Llc Food containers adapted for accommodating pressure changes using skip seals and methods of manufacture
DE102016116098A1 (de) 2016-08-30 2018-03-01 B. Braun Avitum Ag Verschlusskappe für einen kartuschenförmigen Behälter
US10617604B2 (en) 2016-08-30 2020-04-14 B. Braun Avitum Ag End cap for cartridge-shaped receptacle

Also Published As

Publication number Publication date
SE9600215L (sv) 1997-07-23
SE9600215D0 (sv) 1996-01-22
SE508379C2 (sv) 1998-09-28

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