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WO1991015512A3 - Hiv envelope polypeptides - Google Patents

Hiv envelope polypeptides Download PDF

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Publication number
WO1991015512A3
WO1991015512A3 PCT/US1991/002166 US9102166W WO9115512A3 WO 1991015512 A3 WO1991015512 A3 WO 1991015512A3 US 9102166 W US9102166 W US 9102166W WO 9115512 A3 WO9115512 A3 WO 9115512A3
Authority
WO
WIPO (PCT)
Prior art keywords
polypeptides
hiv envelope
envelope polypeptides
antibodies
isolated
Prior art date
Application number
PCT/US1991/002166
Other languages
French (fr)
Other versions
WO1991015512A2 (en
Inventor
Timothy J Gregory
Cordelia K Leonard
Michael W Spellman
Original Assignee
Genentech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genentech Inc filed Critical Genentech Inc
Priority to JP91507619A priority Critical patent/JPH05506221A/en
Publication of WO1991015512A2 publication Critical patent/WO1991015512A2/en
Publication of WO1991015512A3 publication Critical patent/WO1991015512A3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00—Reverse transcribing RNA viruses
    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/16011—Human Immunodeficiency Virus, HIV
    • C12N2740/16111—Human Immunodeficiency Virus, HIV concerning HIV env
    • C12N2740/16122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Virology (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

Novel isolated physiologically active polypeptides are provided, as well as antibodies directed against the isolated polypeptides. Methods for the preparation and pharmaceutical use of the polypeptides and antibodies are also provided.
PCT/US1991/002166 1990-04-03 1991-04-01 Hiv envelope polypeptides WO1991015512A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP91507619A JPH05506221A (en) 1990-04-03 1991-04-01 HIV envelope polypeptide

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US50477290A 1990-04-03 1990-04-03
US504,772 1990-04-03

Publications (2)

Publication Number Publication Date
WO1991015512A2 WO1991015512A2 (en) 1991-10-17
WO1991015512A3 true WO1991015512A3 (en) 1991-12-12

Family

ID=24007676

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1991/002166 WO1991015512A2 (en) 1990-04-03 1991-04-01 Hiv envelope polypeptides

Country Status (5)

Country Link
EP (1) EP0527789A1 (en)
JP (1) JPH05506221A (en)
AU (1) AU7676891A (en)
CA (1) CA2078545A1 (en)
WO (1) WO1991015512A2 (en)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH06501260A (en) * 1990-09-27 1994-02-10 シンテロ　ヴァクシーン　ディベロップメント　ケービー Peptides used for inducing neutralizing antibodies and vaccination against human immunodeficiency virus
CA2114849C (en) * 1991-08-29 2007-04-24 Jay A. Berzofsky Multideterminant peptide antigens that stimulate helper t lymphocyte response to hiv in a range of human subjects
US5869624A (en) * 1993-03-26 1999-02-09 Progenics Pharmaceuticals, Inc. HIV-1 vaccines, antibody compositions related thereto, and therapeutic and prophylactic uses thereof
EP0708659A4 (en) 1993-06-07 2000-08-23 Genentech Inc Hiv envelope polypeptides
DE4405810A1 (en) 1994-02-23 1995-08-24 Behringwerke Ag Peptides derived from a retrovirus from the HIV group and their use
US6585979B1 (en) 1996-07-08 2003-07-01 Genentech, Inc. HIV envelope polypeptides and immunogenic composition
ZA975889B (en) * 1996-07-08 1998-02-23 Genentech Inc HIV envelope polypeptides and vaccine.
GB9615533D0 (en) * 1996-07-24 1996-09-04 Peptide Therapeutics Ltd Diagnostic test for herpes simplex virus type-2
US6271198B1 (en) 1996-11-06 2001-08-07 Genentech, Inc. Constrained helical peptides and methods of making same
AU745101B2 (en) * 1996-11-06 2002-03-14 Genentech Inc. Constrained helical peptides and methods of making same
DK1141315T3 (en) 1998-12-31 2008-05-19 Novartis Vaccines & Diagnostic Modified HIV Env polypeptides
CA2358385C (en) 1998-12-31 2013-08-06 Chiron Corporation Polynucleotides encoding antigenic hiv type c polypeptides, polypeptides and uses thereof
EP2412242A3 (en) 2001-07-05 2012-06-13 Novartis Vaccines and Diagnostics, Inc. Polynucleotides encoding antigenic HIV Type C polypeptides, polypeptides and uses thereof
US20030170614A1 (en) 2001-08-31 2003-09-11 Megede Jan Zur Polynucleotides encoding antigenic HIV type B polypeptides, polypeptides and uses thereof
US8715685B2 (en) * 2009-07-14 2014-05-06 Lucia Irene Gonzalez Stereoisomer peptides and their polymer conjugates for HIV disease

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0279688A2 (en) * 1987-02-20 1988-08-24 Genentech, Inc. Methods and compositions for the use of HIV env polypeptides and antibodies thereto
WO1989002277A2 (en) * 1987-08-28 1989-03-23 Board Of Regents, The University Of Texas System Prophylaxis and therapy of acquired immunodeficiency syndrome
WO1989003844A1 (en) * 1987-10-28 1989-05-05 Ferring Ab Hiv peptides, artificial hiv antigens and immunoassay kits
WO1989005821A1 (en) * 1987-12-21 1989-06-29 Arch Development Corporation Hiv-related antigens and antibodies
EP0326490A2 (en) * 1988-01-27 1989-08-02 Biochem Immunosystems Inc. Synthetic peptides and mixtures thereof for detecting HIV antibodies
EP0328403A2 (en) * 1988-02-12 1989-08-16 United Biomedical Inc. Synthetic peptides related to the HIV-GP120-env-protein, and their use

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0279688A2 (en) * 1987-02-20 1988-08-24 Genentech, Inc. Methods and compositions for the use of HIV env polypeptides and antibodies thereto
WO1989002277A2 (en) * 1987-08-28 1989-03-23 Board Of Regents, The University Of Texas System Prophylaxis and therapy of acquired immunodeficiency syndrome
WO1989003844A1 (en) * 1987-10-28 1989-05-05 Ferring Ab Hiv peptides, artificial hiv antigens and immunoassay kits
WO1989005821A1 (en) * 1987-12-21 1989-06-29 Arch Development Corporation Hiv-related antigens and antibodies
EP0326490A2 (en) * 1988-01-27 1989-08-02 Biochem Immunosystems Inc. Synthetic peptides and mixtures thereof for detecting HIV antibodies
EP0328403A2 (en) * 1988-02-12 1989-08-16 United Biomedical Inc. Synthetic peptides related to the HIV-GP120-env-protein, and their use

Also Published As

Publication number Publication date
EP0527789A1 (en) 1993-02-24
WO1991015512A2 (en) 1991-10-17
JPH05506221A (en) 1993-09-16
CA2078545A1 (en) 1991-10-04
AU7676891A (en) 1991-10-30

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