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UY34032A - Nuevos inhibidores de quinasa - Google Patents

Nuevos inhibidores de quinasa

Info

Publication number
UY34032A
UY34032A UY34032A UY34032A UY34032A UY 34032 A UY34032 A UY 34032A UY 34032 A UY34032 A UY 34032A UY 34032 A UY34032 A UY 34032A UY 34032 A UY34032 A UY 34032A
Authority
UY
Uruguay
Prior art keywords
new
quinasa
inhibitors
quinasa inhibitors
página
Prior art date
Application number
UY34032A
Other languages
English (en)
Inventor
Thormann Michael
Treml Andreas
Almstetter Michael
Koestler Roland
Yehia Nasser
Original Assignee
Origenis Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Origenis Gmbh filed Critical Origenis Gmbh
Publication of UY34032A publication Critical patent/UY34032A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/14—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
    • C07D495/14—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains three hetero rings
    • C07D513/14—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

La presente invención se relaciona con nuevos compuestos de fórmula (I) capaces de inhibir una o más quinasas, especialmente SYK (tirosina quinasa esplénica), LRRK2 (quinasa con repeticiones ricas en leucina 2) y/o MYLK (quinasa de cadena ligera de miosina) o mutantes de estas. Los compuestos encuentran aplicación en el tratamiento de una variedad de enfermedades. Estas enfermedades incluyen enfermedades autoinmunes, enfermedades inflamatorias, enfermedades óseas, metabólicas, neurológicas y neurodegenerativas, cáncer, enfermedades cardiovasculares, alergias, asma, enfermedad de Alzheimer, enfermedad de Parkinson, trastornos de la piel, enfermedades del ojo, enfermedades infecciosas y enfermedades hormonales.
UY34032A 2011-04-21 2012-04-20 Nuevos inhibidores de quinasa UY34032A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP11003373 2011-04-21

Publications (1)

Publication Number Publication Date
UY34032A true UY34032A (es) 2012-11-30

Family

ID=44501589

Family Applications (1)

Application Number Title Priority Date Filing Date
UY34032A UY34032A (es) 2011-04-21 2012-04-20 Nuevos inhibidores de quinasa

Country Status (2)

Country Link
AR (1) AR086196A1 (es)
UY (1) UY34032A (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2936377A1 (en) 2014-01-10 2015-07-16 Shanghai Birdie Biotech, Inc. Compounds and compositions for treating egfr expressing tumors
CN106943597A (zh) 2016-01-07 2017-07-14 博笛生物科技（北京）有限公司 用于治疗肿瘤的抗-egfr组合
MA47079B1 (fr) 2016-12-20 2021-05-31 Astrazeneca Ab Composés amino-triazolopyidines et leur utilisation pour traiter le cancer
CN108794467A (zh) 2017-04-27 2018-11-13 博笛生物科技有限公司 2-氨基-喹啉衍生物
WO2018232725A1 (en) 2017-06-23 2018-12-27 Birdie Biopharmaceuticals, Inc. PHARMACEUTICAL COMPOSITIONS

Also Published As

Publication number Publication date
AR086196A1 (es) 2013-11-27

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Legal Events

Date Code Title Description
110 Patent granted

Effective date: 20211028