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UY30922A1 - 1,1-DIOXO-1-TIA-5,10-DIAZADIBENZOCICLOHEPTENOS USEFUL AS INHIBITORS OF THE HEPATITIS C VIRUS " - Google Patents

1,1-DIOXO-1-TIA-5,10-DIAZADIBENZOCICLOHEPTENOS USEFUL AS INHIBITORS OF THE HEPATITIS C VIRUS "

Info

Publication number
UY30922A1
UY30922A1 UY30922A UY30922A UY30922A1 UY 30922 A1 UY30922 A1 UY 30922A1 UY 30922 A UY30922 A UY 30922A UY 30922 A UY30922 A UY 30922A UY 30922 A1 UY30922 A1 UY 30922A1
Authority
UY
Uruguay
Prior art keywords
inhibitors
diazadibenzocicloheptenos
tia
dioxo
hepatitis
Prior art date
Application number
UY30922A
Other languages
Spanish (es)
Inventor
Tahri Abdellah
Last Stefaan Julien
Rombauts Klara
Cummings Maxwell David
Van Den Broeck Walter Mathilde
Hu Lili
Lory Pedro Migul Jales
Boutton Carlo Willy Maurice
Amssoms Katie Ingrid Eduard
Vendeville Sandrine Marie Helene
Mcgowan David Craig
Origene Nyanguile
Koen Vandyck
Pierre Jean-Marie Bernard Raboisson
Original Assignee
Tibotec Pharm Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tibotec Pharm Ltd filed Critical Tibotec Pharm Ltd
Publication of UY30922A1 publication Critical patent/UY30922A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Health & Medical Sciences (AREA)
  • Communicable Diseases (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Virology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Oncology (AREA)
  • Public Health (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Inhibidores de la replicacion del VHC de la formula (I) sus estereoisomeros, profármacos, tautomeros, racémicos, sales, hidratos o solvatos donde R1a, R1b, R2, R3, R4a Y r4B tienen el significado definido en las reivindicaciones. La presente invencion además se rfiere a procesos para prepara dichos compuestos, composiciones farmacéuticas que los contienen y su uso en la terapia de VHC.Inhibitors of HCV replication of the formula (I) its stereoisomers, prodrugs, tautomers, racemes, salts, hydrates or solvates wherein R1a, R1b, R2, R3, R4a and r4B have the meaning defined in the claims. The present invention also relates to processes for preparing said compounds, pharmaceutical compositions containing them and their use in HCV therapy.

UY30922A 2007-02-16 2008-02-15 1,1-DIOXO-1-TIA-5,10-DIAZADIBENZOCICLOHEPTENOS USEFUL AS INHIBITORS OF THE HEPATITIS C VIRUS " UY30922A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP07102520 2007-02-16

Publications (1)

Publication Number Publication Date
UY30922A1 true UY30922A1 (en) 2008-09-02

Family

ID=38515419

Family Applications (1)

Application Number Title Priority Date Filing Date
UY30922A UY30922A1 (en) 2007-02-16 2008-02-15 1,1-DIOXO-1-TIA-5,10-DIAZADIBENZOCICLOHEPTENOS USEFUL AS INHIBITORS OF THE HEPATITIS C VIRUS "

Country Status (6)

Country Link
AR (1) AR065374A1 (en)
CL (1) CL2008000491A1 (en)
PE (1) PE20081786A1 (en)
TW (1) TW200848057A (en)
UY (1) UY30922A1 (en)
WO (1) WO2008099020A1 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8198305B2 (en) 2007-04-13 2012-06-12 Concert Pharmaceuticals Inc. 1,2-benzisoxazol-3-yl compounds
WO2021030278A1 (en) * 2019-08-12 2021-02-18 Aligos Therapeutics, Inc. Bicyclic compounds

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1398033B1 (en) * 1999-04-30 2009-06-17 The Regents Of The University Of Michigan Use of benzodiazepines for treating autoimmune diseases, inflammations, neoplasies, viral infections and atherosclerosis
JP2008517987A (en) * 2004-10-26 2008-05-29 イステイチユート・デイ・リチエルケ・デイ・ビオロジア・モレコラーレ・ピ・アンジエレツテイ・エツセ・ピー・アー Tetracyclic indole derivatives as antiviral agents

Also Published As

Publication number Publication date
PE20081786A1 (en) 2008-12-18
CL2008000491A1 (en) 2008-08-22
WO2008099020A1 (en) 2008-08-21
TW200848057A (en) 2008-12-16
AR065374A1 (en) 2009-06-03

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