UY27452A1 - Compuestos de benzimidazol sustituido y su uso para el tratamiento del cancer - Google Patents
Compuestos de benzimidazol sustituido y su uso para el tratamiento del cancerInfo
- Publication number
- UY27452A1 UY27452A1 UY27452A UY27452A UY27452A1 UY 27452 A1 UY27452 A1 UY 27452A1 UY 27452 A UY27452 A UY 27452A UY 27452 A UY27452 A UY 27452A UY 27452 A1 UY27452 A1 UY 27452A1
- Authority
- UY
- Uruguay
- Prior art keywords
- cancer treatment
- substituted benzimidazol
- compounds
- benzimidazol compounds
- substituted
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
- C07D235/30—Nitrogen atoms not forming part of a nitro radical
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
- C07D235/30—Nitrogen atoms not forming part of a nitro radical
- C07D235/32—Benzimidazole-2-carbamic acids, unsubstituted or substituted; Esters thereof; Thio-analogues thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Abstract
Nuevos compuestos de benzimidazol y su uso como inhibidores de las cinasas dependientes de la ciclina, y nuevas composiciones farmacológicas que contienen los mismos.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP01402460A EP1298125A1 (en) | 2001-09-26 | 2001-09-26 | Substituted benzimidazole compounds and their use for the treatment of cancer |
Publications (1)
Publication Number | Publication Date |
---|---|
UY27452A1 true UY27452A1 (es) | 2003-02-28 |
Family
ID=8182891
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
UY27452A UY27452A1 (es) | 2001-09-26 | 2002-09-24 | Compuestos de benzimidazol sustituido y su uso para el tratamiento del cancer |
Country Status (35)
Country | Link |
---|---|
US (1) | US7041668B2 (es) |
EP (2) | EP1298125A1 (es) |
JP (1) | JP4510450B2 (es) |
KR (1) | KR100891439B1 (es) |
CN (1) | CN100346786C (es) |
AR (1) | AR037096A1 (es) |
AT (1) | ATE386517T1 (es) |
AU (1) | AU2002337151B2 (es) |
BR (1) | BR0212856A (es) |
CA (1) | CA2461622C (es) |
CO (1) | CO5570675A2 (es) |
CY (1) | CY1107953T1 (es) |
DE (1) | DE60225159T2 (es) |
DK (1) | DK1432417T3 (es) |
EA (1) | EA006802B1 (es) |
ES (1) | ES2301682T3 (es) |
GT (1) | GT200200190A (es) |
HK (1) | HK1068551A1 (es) |
HR (1) | HRPK20040293B3 (es) |
HU (1) | HUP0401756A3 (es) |
IL (1) | IL161059A0 (es) |
ME (1) | MEP16808A (es) |
MX (1) | MXPA04002042A (es) |
MY (1) | MY135339A (es) |
NO (1) | NO327008B1 (es) |
NZ (1) | NZ531246A (es) |
PA (1) | PA8555501A1 (es) |
PE (1) | PE20030427A1 (es) |
PL (1) | PL369527A1 (es) |
PT (1) | PT1432417E (es) |
RS (1) | RS50896B (es) |
SI (1) | SI1432417T1 (es) |
UY (1) | UY27452A1 (es) |
WO (1) | WO2003028721A2 (es) |
ZA (1) | ZA200401887B (es) |
Families Citing this family (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20070010573A1 (en) | 2003-06-23 | 2007-01-11 | Xianqi Kong | Methods and compositions for treating amyloid-related diseases |
AU2011250847B2 (en) * | 2003-06-23 | 2013-06-20 | Bhi Limited Partnership | Methods and compositions for treating amyloid-related diseases |
AU2004283313A1 (en) * | 2003-10-24 | 2005-05-06 | Exelixis, Inc. | TAO kinase modulators and methods of use |
DE102004010207A1 (de) | 2004-03-02 | 2005-09-15 | Aventis Pharma S.A. | Neue 4-Benzimidazol-2-yl-pyridazin-3-on-Derivate |
FR2868421B1 (fr) * | 2004-04-01 | 2008-08-01 | Aventis Pharma Sa | Nouveaux benzothiazoles et leur utilisation comme medicaments |
EP1598348A1 (en) | 2004-05-18 | 2005-11-23 | Aventis Pharma Deutschland GmbH | Novel pyridazinone derivatives as inhibitors of CDK2 |
CA2900876A1 (en) | 2004-12-22 | 2006-08-17 | Bhi Limited Partnership | Methods and compositions for treating amyloid-related diseases |
UA92180C2 (en) * | 2005-09-06 | 2010-10-11 | Смиткляйн Бичам Корпорейшн | Benzimidazole thiophene compounds as plk inhibitors |
FR2891273B1 (fr) * | 2005-09-27 | 2007-11-23 | Aventis Pharma Sa | NOUVEAUX DERIVES BENZIMIDAZOLES ET BENZOTHIAZOLES, LEUR PREPARATION ET LEUR UTILISATION PHARMACEUTIQUE NOTAMMENT COMME INHIBITEURS DE CMet |
CN106946748B (zh) | 2006-10-12 | 2019-02-05 | Bhi有限合资公司 | 递送3-氨基-1-丙磺酸的方法、化合物、组合物和载体 |
PA8792501A1 (es) | 2007-08-09 | 2009-04-23 | Sanofi Aventis | Nuevos derivados de 6-triazolopiridacina-sulfanil benzotiazol y bencimidazol,su procedimiento de preparación,su aplicación como medicamentos,composiciones farmacéuticas y nueva utilización principalmente como inhibidores de met. |
MX350019B (es) * | 2007-10-12 | 2016-12-09 | Abbvie Ireland Unlimited Co | Forma cristalina 1 de 2-((r)-2-metilpirrolidin-2-il)-1h-bencimidaz ol-4-carboxamida. |
FR2922550B1 (fr) | 2007-10-19 | 2009-11-27 | Sanofi Aventis | Nouveaux derives de 6-aryl/heteroalkyloxy benzothiazole et benzimidazole, application comme medicaments, compositions pharmaceutiques et nouvelle utilisation notamment comme inhibiteurs de cmet |
FR2941951B1 (fr) | 2009-02-06 | 2011-04-01 | Sanofi Aventis | Derives de 6-(6-nh-substitue-triazolopyridazine-sulfanyl) benzothiazoles et benzimidazoles : preparation, application comme medicaments et utilisation comme inhibiteurs de met. |
FR2941952B1 (fr) | 2009-02-06 | 2011-04-01 | Sanofi Aventis | Derives de 6-(6-substitue-triazolopyridazine-sulfanyl) 5-fluoro-benzothiazoles et 5-fluoro-benzimidazoles : preparation, application comme medicaments et utilisation comme inhibiteurs de met. |
FR2941949B1 (fr) | 2009-02-06 | 2011-04-01 | Sanofi Aventis | Derives de 6-(6-o-cycloalkyl ou 6-nh-cycloalkyl- triazolopyridazine-sulfanyl)benzothiazoles et benzimidazoles preparation, application comme medicaments et utilisation comme inhibiteurs de met. |
FR2941950B1 (fr) | 2009-02-06 | 2011-04-01 | Sanofi Aventis | Derives de 6-(6-o-substitue-triazolopyridazine-sulfanyl) benzothiazoles et benzimidazoles : preparation, application comme medicaments et utilisation comme inhibiteurs de met. |
WO2011091152A1 (en) * | 2010-01-22 | 2011-07-28 | Pablo Gastaminza | Inhibitors of hepatitis c virus infection |
IL310959A (en) | 2015-08-25 | 2024-04-01 | Alnylam Pharmaceuticals Inc | Methods and preparations for treating a disorder related to the PCSK9 gene |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2441201C2 (de) * | 1974-08-28 | 1986-08-07 | Hoechst Ag, 6230 Frankfurt | Anthelminthisch wirksame 2-Carbalkoxyamino-5(6)-phenyl-sulfonyloxy-benzimidazole und Verfahren zu ihrer Herstellung |
DE2541752A1 (de) * | 1975-09-19 | 1977-03-24 | Hoechst Ag | Anthelminthisch wirksame 2-carbalkoxyamino-5(6)-phenyl-sulfonyloxy- benzimidazole und verfahren zu ihrer herstellung |
DE3247615A1 (de) * | 1982-12-23 | 1984-07-05 | Hoechst Ag, 6230 Frankfurt | Substituierte phenylsulfonyloxybenzimidazolcarbaminate, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel |
GB9900752D0 (en) * | 1999-01-15 | 1999-03-03 | Angiogene Pharm Ltd | Benzimidazole vascular damaging agents |
US6693125B2 (en) * | 2001-01-24 | 2004-02-17 | Combinatorx Incorporated | Combinations of drugs (e.g., a benzimidazole and pentamidine) for the treatment of neoplastic disorders |
-
2001
- 2001-09-26 EP EP01402460A patent/EP1298125A1/en not_active Withdrawn
-
2002
- 2002-09-17 PE PE2002000913A patent/PE20030427A1/es not_active Application Discontinuation
- 2002-09-24 UY UY27452A patent/UY27452A1/es unknown
- 2002-09-25 MY MYPI20023586A patent/MY135339A/en unknown
- 2002-09-25 GT GT200200190A patent/GT200200190A/es unknown
- 2002-09-26 PL PL02369527A patent/PL369527A1/xx not_active Application Discontinuation
- 2002-09-26 IL IL16105902A patent/IL161059A0/xx unknown
- 2002-09-26 SI SI200230686T patent/SI1432417T1/sl unknown
- 2002-09-26 PT PT02772370T patent/PT1432417E/pt unknown
- 2002-09-26 PA PA20028555501A patent/PA8555501A1/es unknown
- 2002-09-26 AR ARP020103629A patent/AR037096A1/es unknown
- 2002-09-26 AU AU2002337151A patent/AU2002337151B2/en not_active Ceased
- 2002-09-26 JP JP2003532053A patent/JP4510450B2/ja not_active Expired - Fee Related
- 2002-09-26 MX MXPA04002042A patent/MXPA04002042A/es active IP Right Grant
- 2002-09-26 BR BR0212856-0A patent/BR0212856A/pt not_active IP Right Cessation
- 2002-09-26 HU HU0401756A patent/HUP0401756A3/hu unknown
- 2002-09-26 EP EP02772370A patent/EP1432417B1/en not_active Expired - Lifetime
- 2002-09-26 CN CNB028187458A patent/CN100346786C/zh not_active Expired - Fee Related
- 2002-09-26 DE DE60225159T patent/DE60225159T2/de not_active Expired - Lifetime
- 2002-09-26 KR KR1020047004365A patent/KR100891439B1/ko not_active IP Right Cessation
- 2002-09-26 NZ NZ531246A patent/NZ531246A/en not_active IP Right Cessation
- 2002-09-26 ES ES02772370T patent/ES2301682T3/es not_active Expired - Lifetime
- 2002-09-26 EA EA200400475A patent/EA006802B1/ru not_active IP Right Cessation
- 2002-09-26 AT AT02772370T patent/ATE386517T1/de active
- 2002-09-26 ME MEP-168/08A patent/MEP16808A/xx unknown
- 2002-09-26 WO PCT/EP2002/011353 patent/WO2003028721A2/en active IP Right Grant
- 2002-09-26 CA CA002461622A patent/CA2461622C/en not_active Expired - Fee Related
- 2002-09-26 RS YUP-214/04A patent/RS50896B/sr unknown
- 2002-09-26 DK DK02772370T patent/DK1432417T3/da active
-
2004
- 2004-03-08 ZA ZA200401887A patent/ZA200401887B/en unknown
- 2004-03-23 NO NO20041214A patent/NO327008B1/no not_active IP Right Cessation
- 2004-03-25 HR HR20040293A patent/HRPK20040293B3/xx not_active IP Right Cessation
- 2004-03-25 US US10/808,889 patent/US7041668B2/en not_active Expired - Fee Related
- 2004-03-25 CO CO04028337A patent/CO5570675A2/es not_active Application Discontinuation
-
2005
- 2005-02-07 HK HK05101028A patent/HK1068551A1/xx not_active IP Right Cessation
-
2008
- 2008-05-20 CY CY20081100526T patent/CY1107953T1/el unknown
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
UY27452A1 (es) | Compuestos de benzimidazol sustituido y su uso para el tratamiento del cancer | |
CR7716A (es) | Uso de inhibidores de la ikb-quinasa para el tratamiento del dolor | |
PA8468401A1 (es) | Compuestos para el tratamiento de la isquemia | |
CU20070160A7 (es) | Pirrolopirazoles, inhibidores potentes de quinasa | |
UY28342A1 (es) | Nuevos compuestos | |
ES2195785B1 (es) | Nuevos derivados de piridazin-3(2h)-ona. | |
SV2003000925A (es) | Derivados espirotriciclicos nuevos y su uso como inhibidores de fosfodiesterasa-7 | |
UY28513A1 (es) | Nuevos compuestos | |
AR067505A1 (es) | Derivados de pirimidinil-piridazinona | |
CO6541643A2 (es) | Derivados de imidazopirina como inhibidores de jak | |
CL2008001743A1 (es) | Uso de un compuesto derivado de quinazolina para tratar el cancer; uso del compuesto y de otro compuesto antineoplasico; compuestos derivados de quinazolina; y composicion farmaceutica que los comprende. | |
SV2010003559A (es) | Algunos derivados de 2-pirazinona y su uso como inhibidores de elastasa de los neutrofilos | |
ECSP034924A (es) | Derivados sustituidos del 1-oxa-2,8-daza-espiro[4,5]dec-2-eno | |
GT200600166A (es) | Derivados de cromano y cromeno y usos de los mismos | |
UY30846A1 (es) | Derivados de oxindol sustituidos, medicamentos que los comprenden y uso de los mismos | |
BRPI0514537B8 (pt) | compostos de aminoeteroarila substituídos com pirazol e composição farmacêutica que os compreende | |
SV2008001369A (es) | Benzimidazoles | |
PA8675701A1 (es) | Nuevos derivados del fluoreno, composiciones que los contienen y su utilización | |
CL2011000489A1 (es) | Compuestos derivados de pirimido[5,4-d]pirimidina, los cuales actuan como inhibidores de tirosina-quinasas; y composiciones farmaceuticas que los comprenden, utiles en el tratamiento de enfermedades que se caracterizan por una proliferacion celular excesiva o anomala | |
UY30748A1 (es) | Compuesto0s novedosos | |
ECSP088821A (es) | Derivados de tioxantina y su uso como inhibidores de la mpo | |
UY28876A1 (es) | Compuestos de morfolina sustituida y composiciones para el tratamiento de trastornos del sistema nervioso central | |
UY29685A1 (es) | Heterociclos de 1,4-dihidropiridina-condensados, procesos para preparar los mismos, uso y composiciones que los contienen. | |
ECSP088584A (es) | Nuevos derivados de benzimidazol como inhibidores del receptor vanilloide 1 (vrl) | |
UY27894A1 (es) | Derivados de cinamida. |