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UY26570A1 - Carboxamidas de pirimidina útiles como inhibidores de isozimas pde4 - Google Patents

Carboxamidas de pirimidina útiles como inhibidores de isozimas pde4

Info

Publication number
UY26570A1
UY26570A1 UY26570A UY26570A UY26570A1 UY 26570 A1 UY26570 A1 UY 26570A1 UY 26570 A UY26570 A UY 26570A UY 26570 A UY26570 A UY 26570A UY 26570 A1 UY26570 A1 UY 26570A1
Authority
UY
Uruguay
Prior art keywords
pirimidine
isozyme
pde4 inhibitors
chronic
carboxamides useful
Prior art date
Application number
UY26570A
Other languages
English (en)
Inventor
Robert James Chambers
Thomas Victor Magee
Anthony Marfat
Original Assignee
Pfizer Prod Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc
Publication of UY26570A1 publication Critical patent/UY26570A1/es

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/32—One oxygen, sulfur or nitrogen atom
    • C07D239/34—One oxygen atom
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    • C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
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  • Virology (AREA)
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  • Diabetes (AREA)
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  • Heart & Thoracic Surgery (AREA)
  • Neurology (AREA)
  • Immunology (AREA)
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  • Communicable Diseases (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Pain & Pain Management (AREA)
  • Epidemiology (AREA)
  • Vascular Medicine (AREA)
  • Dermatology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Biotechnology (AREA)

Abstract

Se describen compuestos de la fórmula (i), se describe además la utilidad de una composición farmacéutica para tratar enfermedades y estados inflamatorios, respiratorios y alérgicos, especialmente el asma; la enfermedad pulmonar obstructiva crónica (COPD), incluyendo la bronquitis crónica, el enfisema y la bronquiectasia; la rinitis crónica; y la sinusitis crónica.
UY26570A 2000-01-31 2001-01-31 Carboxamidas de pirimidina útiles como inhibidores de isozimas pde4 UY26570A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US17928200P 2000-01-31 2000-01-31

Publications (1)

Publication Number Publication Date
UY26570A1 true UY26570A1 (es) 2001-08-27

Family

ID=22655926

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Application Number Title Priority Date Filing Date
UY26570A UY26570A1 (es) 2000-01-31 2001-01-31 Carboxamidas de pirimidina útiles como inhibidores de isozimas pde4

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US (1) US6740655B2 (es)
EP (1) EP1252157B1 (es)
JP (1) JP2003522165A (es)
KR (1) KR20020071029A (es)
CN (1) CN1404480A (es)
AP (1) AP2002002590A0 (es)
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AT (1) ATE269860T1 (es)
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Families Citing this family (85)

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ES2165768B1 (es) 1999-07-14 2003-04-01 Almirall Prodesfarma Sa Nuevos derivados de quinuclidina y composiciones farmaceuticas que los contienen.
JP2003518484A (ja) * 1999-12-24 2003-06-10 グラクソ グループ リミテッド サルメテロールおよびプロピオン酸フルチカゾンの医薬用エアゾル製剤
DE10110772A1 (de) * 2001-03-07 2002-09-12 Boehringer Ingelheim Pharma Neue Arzneimittelkompositionen auf der Basis von Anticholinergika und PDE-IV-Inhibitoren
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