US3926085A - Specimen feed for a microtome - Google Patents
Specimen feed for a microtome Download PDFInfo
- Publication number
- US3926085A US3926085A US528958A US52895874A US3926085A US 3926085 A US3926085 A US 3926085A US 528958 A US528958 A US 528958A US 52895874 A US52895874 A US 52895874A US 3926085 A US3926085 A US 3926085A
- Authority
- US
- United States
- Prior art keywords
- shaft
- carriage
- specimen
- knife
- clutch
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Images
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/02—Devices for withdrawing samples
- G01N1/04—Devices for withdrawing samples in the solid state, e.g. by cutting
- G01N1/06—Devices for withdrawing samples in the solid state, e.g. by cutting providing a thin slice, e.g. microtome
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/02—Devices for withdrawing samples
- G01N1/04—Devices for withdrawing samples in the solid state, e.g. by cutting
- G01N1/06—Devices for withdrawing samples in the solid state, e.g. by cutting providing a thin slice, e.g. microtome
- G01N2001/065—Drive details
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T74/00—Machine element or mechanism
- Y10T74/15—Intermittent grip type mechanical movement
- Y10T74/1503—Rotary to intermittent unidirectional motion
- Y10T74/1524—Intermittently engaged clutch
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T83/00—Cutting
- Y10T83/647—With means to convey work relative to tool station
- Y10T83/6492—Plural passes of diminishing work piece through tool station
- Y10T83/6499—Work rectilinearly reciprocated through tool station
- Y10T83/6508—With means to cause movement of work transversely toward plane of cut
- Y10T83/6515—By means to define increment of movement toward plane of cut
- Y10T83/6516—Interrelated with movement of reciprocating means
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T83/00—Cutting
- Y10T83/647—With means to convey work relative to tool station
- Y10T83/654—With work-constraining means on work conveyor [i.e., "work-carrier"]
- Y10T83/6563—With means to orient or position work carrier relative to tool station
- Y10T83/6566—By indexing means
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T83/00—Cutting
- Y10T83/647—With means to convey work relative to tool station
- Y10T83/6584—Cut made parallel to direction of and during work movement
Definitions
- a manuan y pos1t1onable cam surface mounted on the [58] new of Search 83/412 717, 7181 frame of a microtome is used to control the amount of 83/9155 425; 74/1255 571 R rotation of a single direction clutch for driving a feed screw to advance a tissue specimen toward a knife be- [56] References and tween the cutting strokes of the microtome.
- This invention relates to microtomes and in particular to a feed device for advancing the specimen toward the knife between cutting strokes of the microtome.
- microtomes frequently utilize a paw and gear or ratchet type of mechanism to advance the specimen toward the knife between each cutting stroke of the microtome. Adjustment of such mechanism is limited to multiples of the smallest increment available as a result of tube spacing and the like.
- the present invention is directed to a microtome utilizing a single direction clutch to transmit motion to feed screw for advancing a specimen toward the knife between cutting strokes and a manually positionable cam for controlling the amount of motion of the feed screw to provide an infinitely adjustable selection of specimen thickness.
- FIG. 1 is a side view of a microtome
- FIG. 2 is a front view, partly in section, of the microtome
- FIG. 3 is a top view, partly in section, of the microtome showing the specimen advance mechanism and single direction clutch;
- FIG. 4 is an enlarged back view of the actuating finger and cam surface controlling the amount of specimen feed with the carriage approaching the limit of the return stroke;
- FIG. 5 is another enlarged back view of the actuating finger and cam surface with the carriage at the limit of the return stroke
- FIG. 6 is an enlarged view of the fast advance hand wheel and connection to the single direction clutch shown partially in cross-section;
- FIG. 7 is an enlarged front view of the disengagement mechanism for rapid advance and withdrawal of the specimen arm.
- FIG. 8 is a partial enlarged front view of the disengagement mechanism.
- a base 1 has a housing 2 and cover 3.
- the base 1 supports holder 4 which carries knife 5 secured by thumb screw 6.
- a specimen (not shown) is held in specimen arm 7 by clamp screw 8.
- Manual rotation of crank 9 using knob 10 causes the specimen arm 7 to move in a reciprocal path as shown by the double ended arrow.
- Hand wheel 11 is provided to rapidly advance or withdraw the specimen from the vicinity of knife 5. 5
- base 1 has support with carriage l3 slideably mounted thereon.
- Carriage 13 has an elongated groove 14 adapted to slideably position dovetail portion 15 of specimen arm 7.
- Rotary motion of crank 10 istransrnitted to carriage 13 by means of eccentric 16 mounted on drivewheel 17 and carried by shaft 18 which is driven in turn by crank 9.
- FIG. 3 a top view of the microtome is shown partially sectioned along line 33.
- a disc 19 having cam surface 20 is carried by shaft 21 which is manually rotatable through knob 22.
- carriage 13 moves up on support 12 in a direction toward shaft 21.
- finger 23 contacts cam surface 20 causing finger 23 mounted on single direction clutch 24 to rotate until the carriage reaches the limit of the return stroke.
- Rotation of the single direction clutch 24 is transmitted to shaft 25 rotatably mounted on slide 13.
- Shaft 25 has threaded portion 26 engaging a complimentary threaded bore 27 in the dovetail portion 15 of specimen arm 7, which converts the rota tional motion of shaft 25 to longitude motion of specimen arm 7.
- FIG. 4 shows an enlarged back view of the portion of support 12 carrying disc 19 and cam surface 20.
- Carriage 13 is approaching the limit of the reciprocal path on the return stroke and finger 23 is almost in contact with cam surface 20.
- FIG. 5 is another enlarged back view of the portion of the support 12 with carriage 13 at the extreme limit of the reciprocal path of the return stroke.
- finger 23 contacts cam surface 20 thereby rotating single direction clutch 24.
- the rotational movement is transmitted to shaft 25 until the limit of the reciprocal path is reached and movement of finger 23 stops.
- finger 23 returns to its normal position as shown in FIG. 4 due to the biasing action of spring 28, which has one end fastenen to carriage l3 and the other end to finger 23.
- the return of finger 23 to its normal position as shown in FIG. 4 does not transmit rotary motion to shaft 25 because the mechanism (not shown) of single direction clutch 24 only transmits rotary motion in one direction, i.e. the feed direction.
- the distance specimen arm 7 is advanced toward knife 5 is controlled by the manually preselected rotational position of disc 19 and cam surface 20.
- the continuous curved surface 20 of disc 19 enables one to preselect an incrementally variable cutting advance within the limits of the range provided, since the arc through which single direction clutch 24 and shaft 25 are rotated controls the amount of specimen feed toward knife 5 produced by threaded portion 26 on shaft 25.
- Handwheel 11 has means to provide disengagement from single direction clutch 24 when rotation to withdraw the specimen is desired.
- the means for disengagement of handwheel 11 from single direction clutch 24 includes a bushing 38 mounted near the periphery of handwheel 11 carrying knob 29 with a slideable pin 30 passing through the center of knob 29 and bushing 38.
- Pin 30 is of sufficient length to extend beyond knob 29 and has a collar 32 mounted thereon to provide a normally biased position as shown in FIG. 7 in cooperation with spring 33, pin 30, has a tapered end extending through handwheel 11 which, when pressed, rotates extension 34 of lock 35 pivoted on screw 36.
- Spring 37 normally biases 35 into one of a plurality of notches 39 (one shown) located in the peripheral portion of clutch 24. As shown in FIG. 8 pin 30 is depressed toward handwheel 11, lock 35 is removed from notch 39 as shown in FIG. 8 and handwheel 1 1 is free to be rapidly rotated in a direction against the feed without interference from the single direction clutch.
- the feed mechanism is operating during the re- 3 turn stroke of specimen arm 7, rotation, of single direction clutch 24 produced by contact of cam surface against finger 23, is transmitted to shaft through lock 35 engaging single direction clutch 24.
- the single direction clutch 24 permits shaft 25 to be freely rotated in the direction producing longitudinal motion of the specimen arm 7 toward knife 5, it is unnecessary to disengage the single direction clutch before rapidly advancing the specimen.
- a microtome having a base, a support extending from said base, a carriage slideably mounted on said support, a manually operable drive means to move said carriage in a reciprocating path along said support, a manually positionable actuator on said support positionable along an axis parallel to the reciprocating path, a slideable specimen holder arm extending from said carriage in a direction generally perpendicular to the reciprocating path, means for holding a specimen in the distal end of said arm, a knife adjustably mounted on said base and positioned to cut said specimen as said carriage travels along said reciprocating path in one direction, an incremental feed means connecting said arm and said carriage, said feed means including a shaft mounted on said carriage, one end of said shaft being threaded, means mounted in said arm to engage the threads on said shaft, a clutch mounted on the other end of said shaft, said clutch being adapted to rotate said shaft in a single direction to advance the specimen toward said knife, a finger mounted to and extending from said clutch, said finger being adapted to engage said actuator as said carriage travels
- said manually positionable actuator includes a shaft mounted on said support, a disc mounted on said shaft, said disc having a cam positioned to engage said finger as said carriage travels along said reciprocating path in the other direction, and manual means to selectively rotate said disc to provide incremental adjustment of the cam surface to vary the amount of are said shaft is rotated and the resultant feed of said specimen toward said knife.
Landscapes
- Physics & Mathematics (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Sampling And Sample Adjustment (AREA)
Abstract
Description
Claims (2)
Priority Applications (7)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US528958A US3926085A (en) | 1974-12-02 | 1974-12-02 | Specimen feed for a microtome |
DE2538318A DE2538318C2 (en) | 1974-12-02 | 1975-08-26 | Sample advance for a microtome |
CA234,246A CA1043212A (en) | 1974-12-02 | 1975-08-27 | Specimen feed for a microtome |
AT0661075A AT374282B (en) | 1974-12-02 | 1975-08-27 | MICROTOM |
GB35751/75A GB1495684A (en) | 1974-12-02 | 1975-08-29 | Specimen feed for a microtome |
SE7509772A SE405419B (en) | 1974-12-02 | 1975-09-03 | MICROTOM |
JP50109051A JPS5819974B2 (en) | 1974-12-02 | 1975-09-10 | microtome |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US528958A US3926085A (en) | 1974-12-02 | 1974-12-02 | Specimen feed for a microtome |
Publications (1)
Publication Number | Publication Date |
---|---|
US3926085A true US3926085A (en) | 1975-12-16 |
Family
ID=24107929
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US528958A Expired - Lifetime US3926085A (en) | 1974-12-02 | 1974-12-02 | Specimen feed for a microtome |
Country Status (7)
Country | Link |
---|---|
US (1) | US3926085A (en) |
JP (1) | JPS5819974B2 (en) |
AT (1) | AT374282B (en) |
CA (1) | CA1043212A (en) |
DE (1) | DE2538318C2 (en) |
GB (1) | GB1495684A (en) |
SE (1) | SE405419B (en) |
Cited By (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4395075A (en) * | 1982-03-24 | 1983-07-26 | E. I. Du Pont De Nemours & Co. | Misalignment system for a microtome |
FR2529676A1 (en) * | 1982-06-30 | 1984-01-06 | Reichert Optische Werke Ag | MICROTOME HAVING MEANS ADAPTED IN ADVANCE OF THE SPECIMEN CARRIER ARM AND / OR KNIFE |
US4594929A (en) * | 1984-02-07 | 1986-06-17 | Parke, Davis & Company | Microtome having specimen retraction means |
WO1995014219A1 (en) * | 1993-11-16 | 1995-05-26 | Walter Ganter | Microtome |
US5782572A (en) * | 1996-02-05 | 1998-07-21 | Leica Instruments Gmbh | Positioning device |
US5881626A (en) * | 1995-08-26 | 1999-03-16 | Leica Instruments Gmbh | Rotary microtome with a crank mechanism |
US20100000390A1 (en) * | 2008-07-01 | 2010-01-07 | Reiner Fank | Linear movement length setting for rotary microtome |
US20100180742A1 (en) * | 2007-06-06 | 2010-07-22 | Leica Biosystems Nussloch Gmbh | Device And Method For Braking A Shaft Of A Microtome |
WO2013095972A3 (en) * | 2011-12-21 | 2013-08-15 | Sakura Finetek U.S.A., Inc. | Reciprocating microtome drive system |
US8869666B2 (en) | 2011-03-24 | 2014-10-28 | Sakura Finetek U.S.A., Inc. | Microtome with surface orientation sensor to sense orientation of surface of sample |
US11333582B2 (en) * | 2017-11-30 | 2022-05-17 | Leica Biosystems Nussloch Gmbh | Controlling a motorized microtome |
Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US1026280A (en) * | 1910-09-19 | 1912-05-14 | Spencer Lens Co | Microtome. |
US2155523A (en) * | 1935-04-26 | 1939-04-25 | Bausch & Lomb | Microtome |
US2592237A (en) * | 1950-01-11 | 1952-04-08 | Builders Iron Foundry | Pump stroke adjusting device |
US3212379A (en) * | 1962-10-26 | 1965-10-19 | Ames Lab Tek Inc | Microtome having means to incrementally feed the cutting blade toward the specimen carrier |
US3293972A (en) * | 1964-09-08 | 1966-12-27 | Compur Werk Gmbh & Co | Microtome |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE45504C (en) * | G. Baltzar und E. Zimmermann in Leipzig | Microtome with fixed knife and automatic advancement of the object | ||
US930686A (en) * | 1907-12-28 | 1909-08-10 | Bausch & Lomb Optical Co | Microtome. |
DE414153C (en) * | 1924-03-11 | 1925-05-25 | Wilhelm Loew Dr | Microtome with automatic adjustment of the section thickness through the drive axis |
-
1974
- 1974-12-02 US US528958A patent/US3926085A/en not_active Expired - Lifetime
-
1975
- 1975-08-26 DE DE2538318A patent/DE2538318C2/en not_active Expired
- 1975-08-27 AT AT0661075A patent/AT374282B/en active
- 1975-08-27 CA CA234,246A patent/CA1043212A/en not_active Expired
- 1975-08-29 GB GB35751/75A patent/GB1495684A/en not_active Expired
- 1975-09-03 SE SE7509772A patent/SE405419B/en not_active IP Right Cessation
- 1975-09-10 JP JP50109051A patent/JPS5819974B2/en not_active Expired
Patent Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US1026280A (en) * | 1910-09-19 | 1912-05-14 | Spencer Lens Co | Microtome. |
US2155523A (en) * | 1935-04-26 | 1939-04-25 | Bausch & Lomb | Microtome |
US2592237A (en) * | 1950-01-11 | 1952-04-08 | Builders Iron Foundry | Pump stroke adjusting device |
US3212379A (en) * | 1962-10-26 | 1965-10-19 | Ames Lab Tek Inc | Microtome having means to incrementally feed the cutting blade toward the specimen carrier |
US3293972A (en) * | 1964-09-08 | 1966-12-27 | Compur Werk Gmbh & Co | Microtome |
Cited By (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4395075A (en) * | 1982-03-24 | 1983-07-26 | E. I. Du Pont De Nemours & Co. | Misalignment system for a microtome |
FR2529676A1 (en) * | 1982-06-30 | 1984-01-06 | Reichert Optische Werke Ag | MICROTOME HAVING MEANS ADAPTED IN ADVANCE OF THE SPECIMEN CARRIER ARM AND / OR KNIFE |
US4594929A (en) * | 1984-02-07 | 1986-06-17 | Parke, Davis & Company | Microtome having specimen retraction means |
WO1995014219A1 (en) * | 1993-11-16 | 1995-05-26 | Walter Ganter | Microtome |
US5881626A (en) * | 1995-08-26 | 1999-03-16 | Leica Instruments Gmbh | Rotary microtome with a crank mechanism |
US5782572A (en) * | 1996-02-05 | 1998-07-21 | Leica Instruments Gmbh | Positioning device |
US20100180742A1 (en) * | 2007-06-06 | 2010-07-22 | Leica Biosystems Nussloch Gmbh | Device And Method For Braking A Shaft Of A Microtome |
US8353232B2 (en) * | 2007-06-06 | 2013-01-15 | Leica Biosystems Nussloch Gmbh | Device and method for braking a shaft of a microtome |
US20100000390A1 (en) * | 2008-07-01 | 2010-01-07 | Reiner Fank | Linear movement length setting for rotary microtome |
US8869666B2 (en) | 2011-03-24 | 2014-10-28 | Sakura Finetek U.S.A., Inc. | Microtome with surface orientation sensor to sense orientation of surface of sample |
US9347857B2 (en) | 2011-03-24 | 2016-05-24 | Sakura Finetek U.S.A., Inc. | Microtome with surface orientation sensor to sense orientation of surface of sample |
CN104081181A (en) * | 2011-12-21 | 2014-10-01 | 美国樱花检验仪器株式会社 | Reciprocating microtome drive system |
US9032854B2 (en) | 2011-12-21 | 2015-05-19 | Sakura Finetek U.S.A., Inc. | Reciprocating microtome drive system |
AU2012355716B2 (en) * | 2011-12-21 | 2016-04-14 | Sakura Finetek U.S.A., Inc. | Reciprocating microtome drive system |
WO2013095972A3 (en) * | 2011-12-21 | 2013-08-15 | Sakura Finetek U.S.A., Inc. | Reciprocating microtome drive system |
CN104081181B (en) * | 2011-12-21 | 2016-12-07 | 美国樱花检验仪器株式会社 | Reciprocating slicer drive system |
US9921137B2 (en) | 2011-12-21 | 2018-03-20 | Sakura Finetek U.S.A., Inc. | Reciprocating microtome drive system |
EP3370055A1 (en) | 2011-12-21 | 2018-09-05 | Sakura Finetek U.S.A., Inc. | Reciprocating microtome drive system |
US11187625B2 (en) | 2011-12-21 | 2021-11-30 | Sakura Fineiek U.S.A., Inc. | Reciprocating microtome drive system |
US11333582B2 (en) * | 2017-11-30 | 2022-05-17 | Leica Biosystems Nussloch Gmbh | Controlling a motorized microtome |
Also Published As
Publication number | Publication date |
---|---|
DE2538318C2 (en) | 1986-05-15 |
JPS5165487A (en) | 1976-06-07 |
AT374282B (en) | 1984-04-10 |
CA1043212A (en) | 1978-11-28 |
ATA661075A (en) | 1983-08-15 |
JPS5819974B2 (en) | 1983-04-21 |
GB1495684A (en) | 1977-12-21 |
SE405419B (en) | 1978-12-04 |
DE2538318A1 (en) | 1976-08-12 |
SE7509772L (en) | 1976-06-03 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
AS | Assignment |
Owner name: WARNER LAMBERT TECHNOLOGIES, INC.; 6373 STEMMONS F Free format text: ASSIGNMENT OF ASSIGNORS INTEREST.;ASSIGNOR:WARNER LAMBERT COMPANY;REEL/FRAME:004034/0700 Effective date: 19820514 Owner name: WARNER LAMBERT COMPANY, 201 TABOR ROAD, MORRIS PLA Free format text: ASSIGNMENT OF ASSIGNORS INTEREST.;ASSIGNOR:AMERICAN OPTICAL CORPORATION,;REEL/FRAME:004034/0681 Effective date: 19820513 |
|
AS | Assignment |
Owner name: CAMBRIDGE INSTRUMENTS INC., A DE CORP. Free format text: ASSIGNMENT OF ASSIGNORS INTEREST.;ASSIGNOR:WARNER LAMBERT TECHNOLOGIES, INC.;REEL/FRAME:004893/0097 Effective date: 19880407 |