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US2366053A - Container for implantation tablets - Google Patents

Container for implantation tablets Download PDF

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Publication number
US2366053A
US2366053A US415346A US41534641A US2366053A US 2366053 A US2366053 A US 2366053A US 415346 A US415346 A US 415346A US 41534641 A US41534641 A US 41534641A US 2366053 A US2366053 A US 2366053A
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United States
Prior art keywords
container
tablet
needle
stopper
tube
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
US415346A
Inventor
Putter Erich
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Merck Sharp and Dohme LLC
Original Assignee
Schering Corp
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Publication date
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Priority to US415346A priority Critical patent/US2366053A/en
Application granted granted Critical
Publication of US2366053A publication Critical patent/US2366053A/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0069Devices for implanting pellets, e.g. markers or solid medicaments

Definitions

  • the ltwo g ass-irodsd J have I an external di-. ameter onlygslightly llessathan ,the inside diameter 1 of/thegcontainergor tube .Fzso that they 1 :fit fairly snu ly withinttheitube and yet can -be readi1y:removed therefrom.
  • the :length x of the ,two l glass rodsiq J isrsuch that their ends just engage theform between tllemva-lrela-tively elosed: chamber, whoseend wallsz vgentlyl presssupo'n the. endsi of l the tablet (seeeFig.
  • the lengthg t l'the flt'ablet is approximately equal to the length of the loading end B of the trocarneedle t ,Inbthez: words; the dengthtof the tube l or .container I is equal to approximately -twice the lengthof the loading end B of lthe trocarlneedlelminus theileng-thtof-thetablet El
  • the "loading ends-Bid then-needle is; inserted through the tneedle and "into the body "of” the patient.
  • the container may have a closed end asis illustrated in Fig. 5 of the drawing, the closed end in this embodiment taking the place of the end of one. of the glass rods J and being spacedfrom the mouth of the container F a distance approximately equal to the length of the loading end B of the, trocar needle.
  • the parts shown in Fig. 5 are similar to the corresponding parts shown in the container illustrated in Figs. 1 and 2.
  • a container fora medicinal tablet comprising an elongated glass tube, open at both ends and formed at such ends to receive closure members, said container being continuous throughout its length and having an interior diameter such as to prevent material transverse movement of the tablet'to be contained therein, closure members for said container ends, glass rods connected to said closure members and extending therefrom to points within the tube, the lengths of said rods being such that when said closure members are in position on said glass tube, the free ends of said rods will just engage the ends of a tablet deposited therein and will confine such tablet against longitudinal movement in the container.
  • a container such as definedin claim 1 in which the interior diameter of said tube is only slightly greater than the diameter of said glass rods so that in the-region of said tube intermediate the ends of said glass rodsthere isprovided a substantiallyclosed chamber for the tablet.
  • a container for a medicinal tablet comprisof the tablet to be carried therein and having a stop against which one end of such tablet is to abut, a stopper forsaid container including a closure coacting with the latter to eifeotively seal the opening for such stopper against the entry of contaminating material and a retaining rod extending into the body of the container, the length of said retaining rod being less than the length of said container body and being such that When the stopper is in position on the container, the free end thereof can just engage the other end of the-tablet adjacent to said stop, and stop means provided on said stopper and coacting with said container body to limit the insertion ofsaid retaining rod therein and to position the latter so that when said closure effectively sealsthe opening for such stopper, the free end of said rod will be in position to cooperate with said sto to positively confine the tablet against material longitudinal movement in the container.
  • a container for a medicinal tablet comprising an elongated tubular body open at both ends and formed at such ends to receive stoppers, said ing an elongated body having a tablet containing tubular body having intermediate its ends a tablet containing portion whose interior diameter is such as to prevent material transversegmovement in positidn on the container, the free ends thereof can just engage the ends of a tablet carried in such container, and stop means provided on said stoppers and coacting with the ends of said container body tolimit the insertion of said retaining rods therein and to position the latter so that when said closures efiectively seal the openings for such stoppers, the free ends of said rods will be in position to positively confine the tablet against material longitudinal movement in the container.
  • a container for a medicinal tablet comprising an elongated bodyclosed at one end and open at the other end to receive a stopper, said elongated body .being continuous throughout its length and having an interior cross-sectional area such as to prevent materialtransverse movement ofthe table-t to be carried therein, a stopper for said container including a closure coacting with the latter to effectively seal the opening for such stopper againstthe entry of contaminating material and a retaining rod extending into the body of the container, the length of saidretaining rod beingless than the length of said container body and being such thatwwhen the stopper is in position on the container, the free end thereof can just engage a tabletpositioned against the closed end of such container body, and stop means provided on said stopper and coacting with the open end of said container body to limit the insertion of saidretaining rod thereinand toposition the latter so that when said; closure effectively seals the opening forsuch stopper, the free end of said rod willbein position to cooperate with the closed end of said container body to positively confine the tablet against material long

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Dermatology (AREA)
  • Medical Informatics (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)

Description

Dec. 26, 1944.
r E. PUTTER CONTAINER FOR IM PLANTATION TABLETS Filed Oct. 17, 1941 INVENTOR Ema/f Farms/2 BY k kw.
WVITNESS ATTORNEYS Patented nealze, 1944 monmmnmrommPLA mATmN msBm rs.
mApplicalt i'ojiizfictobeml'l, 1941,2Serlalhlzo: 41534 L "'GSGIaimS. r01. fete- 6am "This invention relates to an improved container tabletefrom themontainer to the needle but to removeealsq then cotton iin whieh it was wrapped for v lprotection. f rms :is ma tedious-endldiificult procedureland fithe physic'lan iis at all careless the tablet isiaptaxto be eontamin'atedlsEurthera more wtablets'. of ithis nature readily- .crumble: iand disintegrate v o that .if they are not Lhandled carefully lmtheir rtransferito the needle; Vtheyiare -a'pt l to become lbroken: or seduced inwsize; andads such tablets are :made inl-exaciicdosages this may-prove seriouswandkdangerous. l l x JI'he:purpose:ofuthevpresentlinvention v-is to pm- "In accordanoe wi th thiszlinyeiitiongltherzltablet El -isopaekedli for=-=sale inna sterilized elongated l m' ub i sw hzuhasl lazinside.diameter only slightly greater than the =outSide1. diametercofithe loading endiBlcif-itheineedle so thatxwhile' the flatter may be readily insehted itherein, thereiis prevented an .unnecessanyiplaygrbetweene 'such parts whi ithe lbading end B df thezzneedle 11s inserted in thel itubelrFtanditduring the transferrenceifif vide an weimprovedarcontainerwvhichwill enable the iready transfen of: the implantatiomtablet contained therein to .tthe'ilphysicianisuneedle without any .adanger;oflcontaminating lthegltabletwor damP LQthersoDjeetsa'as welliiasl the advantage iiand constructionzofvfilhisrnovelmontainer will become apparent after a perusal of the following .descri-p tion, :readl .in -connectionnwith the flaccompanying drawing, in" which Fig. #21 ils ta iperspeetive view i of l the. container; illustratingxthe'rmanner in :which the tablet-i151 packed wherein; wFig. 2 his: an I .exploded, 'perspeetivewiew showingthe .partslof :the container in :disassembledi condition 1 Fig.3 3 ist: a 'per'spedtive view.illiistratingi'onelmanner inawhieh tube sandicontaminating l the tabletE. 1 Axbead' is the trooarrneedleimayi be loaded fromlithe contamer ,Fig. :14 is zamerspectiye view. illustrating the:next:steptimloadingdiheztrocar needle andEig.
Before: takingwuptthe dGSCEiIItiOH Of'J- LthG- COD- tainer, it :is; deemed: advisable; to iconsiderr briefiy the construction of lithe type 0f troear *needle whichtis usuallyautilizediin inserting' an implantation tablet iritomhe bo'dy- 'of the "patient. As is which is divided intoaneetlle-=end -A'rand aload-u ing end B by means or a knurled collar C whieh serves as ea finger "piece. "The loadlngend *B "of the needle" is cut *away at its outer extremity "to i provide =a*trou'gh-'1-1k'e' portion-D upon which is placed the impl'antationiztabletE "to 5 be: passed the tablet E from theicontaineri l he 'glassiitube i F4! 15:: enlargedat l-its ends xto provide=two:mouths GpG adapted toi-receive stopl ers lfi H, the router endsvof suehwmouths being .:preferab1y:i rovide d with loeadsii 1,:1'. Eaoh ot the stoppers i vidediwithwg'lass rod .l andyiwhen made of rubber,
preferably ;.with eamijnte'grali' substantially c an; dricallytshaped'ssealingcap iKwvhichlprior ito the sealinglluofcthezstopperz in; :placeroncthe tubesiF or during the removahofisuchstopper;extends:out+ wardly:from lthesstbppenzflgvas :istshowmincEigsZ of the drawing, awhilelwhen lathe stopperwistin place on the end of the tubeF, such cap :25 extendswroyer ltheamouth G :0f the tube, :as is shown sealragainst; extraneous matter enteringyinto the providedion lthenouter enduofzzthe .cap K to .lock the; latterximposition i011 a the' container with @051. tively removed therefrom. x
{The ltwo g ass-irodsd J have I an external di-. ameter onlygslightly llessathan ,the inside diameter 1 of/thegcontainergor tube .Fzso that they 1 :fit fairly snu ly withinttheitube and yet can -be readi1y:removed therefrom. (The :length x of the ,two l glass rodsiq J isrsuch that their ends just engage theform between tllemva-lrela-tively elosed: chamber, whoseend wallsz vgentlyl presssupo'n the. endsi of l the tablet (seeeFig. 1) to ,prevent it lfromimoving materially qin the container and to protect wit against. destruction iondamage l-durlr gl handling. This gentIex-pressing' efieotais tenhanoed Fbyj =the cushio ingeontaet of the -rods,J,-Jwit h the walls of theeontainer through the rubber stoppers :H;
H. lIt willaalsotbe observed fr m- -t edr Wini:
(rl tefigsti and. a) that thel-lengthtoi each :md
arms the lengthg t l'the flt'ablet is approximately equal to the length of the loading end B of the trocarneedle t ,Inbthez: words; the dengthtof the tube l or .container I is equal to approximately -twice the lengthof the loading end B of lthe trocarlneedlelminus theileng-thtof-thetablet El Thus whenithe "loading ends-Bid then-needle is; inserted through the tneedle and "into the body "of" the patient.
intollthe vcontai'nert with lthe oollar Cthereof in e ig e tw ineiheb de end-{i e tainer theouterextremity D of such needle end so that the latter may be. wholly inserted into the container in the manner described, there is little likelihood of a mishap in the transfer of the tablet or the'contamination thereof.
It will be evident from the foregoing, that when the end B of the needle is inserted into the container in the manner explainedthe tablet E will become positioned on the U-shaped or troughlike extremity D of such end of the needle. The tablet therefore can be readily removed from the container and forced further into the needle to readyit for application to the patient by means of a sterilized push rod L, as is shown in Fig.
4 of the drawing. -As an alternative, the other stopper H and glass rod J attached thereto can ,also be removed and the push rod L' which is slightly smaller in diameter than thebore of the tube F, inserted into the open end of such tube to push the tablet E home within the needle. It will t us be seen that the loading of the needle is made quite simple and there is removed any danger of the tablet E becoming contaminated during the loading of the needle.
Instead of providing ,tWO stoppers and glass rods for the container, the container may have a closed end asis illustrated in Fig. 5 of the drawing, the closed end in this embodiment taking the place of the end of one. of the glass rods J and being spacedfrom the mouth of the container F a distance approximately equal to the length of the loading end B of the, trocar needle. In all other respects the parts shown in Fig. 5 are similar to the corresponding parts shown in the container illustrated in Figs. 1 and 2.
I claim: 1. A container fora medicinal tablet comprising an elongated glass tube, open at both ends and formed at such ends to receive closure members, said container being continuous throughout its length and having an interior diameter such as to prevent material transverse movement of the tablet'to be contained therein, closure members for said container ends, glass rods connected to said closure members and extending therefrom to points within the tube, the lengths of said rods being such that when said closure members are in position on said glass tube, the free ends of said rods will just engage the ends of a tablet deposited therein and will confine such tablet against longitudinal movement in the container.
2. A container such as definedin claim 1, in which the interior diameter of said tube is only slightly greater than the diameter of said glass rods so that in the-region of said tube intermediate the ends of said glass rodsthere isprovided a substantiallyclosed chamber for the tablet.
3. A container such as defined in claim 1, in which said closure members are made of rubber and are provided with cylindrically shaped capping portions adapted to overlie the portions of the tube surrounding the body portions of said members and to maintain the ends of the glass rods in cushioned engagement with the ends of the tablet.
4. A container for a medicinal tablet comprisof the tablet to be carried therein and having a stop against which one end of such tablet is to abut, a stopper forsaid container including a closure coacting with the latter to eifeotively seal the opening for such stopper against the entry of contaminating material and a retaining rod extending into the body of the container, the length of said retaining rod being less than the length of said container body and being such that When the stopper is in position on the container, the free end thereof can just engage the other end of the-tablet adjacent to said stop, and stop means provided on said stopper and coacting with said container body to limit the insertion ofsaid retaining rod therein and to position the latter so that when said closure effectively sealsthe opening for such stopper, the free end of said rod will be in position to cooperate with said sto to positively confine the tablet against material longitudinal movement in the container. 7 l l 5. A container for a medicinal tablet compris ing an elongated tubular body open at both ends and formed at such ends to receive stoppers, said ing an elongated body having a tablet containing tubular body having intermediate its ends a tablet containing portion whose interior diameter is such as to prevent material transversegmovement in positidn on the container, the free ends thereof can just engage the ends of a tablet carried in such container, and stop means provided on said stoppers and coacting with the ends of said container body tolimit the insertion of said retaining rods therein and to position the latter so that when said closures efiectively seal the openings for such stoppers, the free ends of said rods will be in position to positively confine the tablet against material longitudinal movement in the container. l
6. A container for a medicinal tablet comprising an elongated bodyclosed at one end and open at the other end to receive a stopper, said elongated body .being continuous throughout its length and having an interior cross-sectional area such as to prevent materialtransverse movement ofthe table-t to be carried therein, a stopper for said container including a closure coacting with the latter to effectively seal the opening for such stopper againstthe entry of contaminating material and a retaining rod extending into the body of the container, the length of saidretaining rod beingless than the length of said container body and being such thatwwhen the stopper is in position on the container, the free end thereof can just engage a tabletpositioned against the closed end of such container body, and stop means provided on said stopper and coacting with the open end of said container body to limit the insertion of saidretaining rod thereinand toposition the latter so that when said; closure effectively seals the opening forsuch stopper, the free end of said rod willbein position to cooperate with the closed end of said container body to positively confine the tablet against material longi tudinalmovement in the'containerJ ERICH PU'If'IER.
US415346A 1941-10-17 1941-10-17 Container for implantation tablets Expired - Lifetime US2366053A (en)

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Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2645335A (en) * 1950-05-26 1953-07-14 Zippo Mfg Co Flint dispenser
US3025953A (en) * 1958-01-20 1962-03-20 Diamond Lab Pellet magazine
FR2437218A1 (en) * 1978-09-27 1980-04-25 Lilly Co Eli PACKAGING, DEVICE AND METHOD FOR THE USE OF IMPLANTS
US4712681A (en) * 1984-12-27 1987-12-15 Branemark Per Ingvar Method of packaging artificial implants in sterile and contamination-free manner and a package therefor
FR2867967A1 (en) * 2004-03-24 2005-09-30 Braun Medical Soc Par Actions Oriented unit e.g. vascular filter, transmission device for asymmetrical prosthesis, has elongated body delimiting cavity, and reversible cartridge covered with orientation signs characterizing orientation of oriented unit in cartridge
US20210369945A1 (en) * 2018-06-25 2021-12-02 Sanofi Packaging for a medicament container

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2645335A (en) * 1950-05-26 1953-07-14 Zippo Mfg Co Flint dispenser
US3025953A (en) * 1958-01-20 1962-03-20 Diamond Lab Pellet magazine
FR2437218A1 (en) * 1978-09-27 1980-04-25 Lilly Co Eli PACKAGING, DEVICE AND METHOD FOR THE USE OF IMPLANTS
US4712681A (en) * 1984-12-27 1987-12-15 Branemark Per Ingvar Method of packaging artificial implants in sterile and contamination-free manner and a package therefor
FR2867967A1 (en) * 2004-03-24 2005-09-30 Braun Medical Soc Par Actions Oriented unit e.g. vascular filter, transmission device for asymmetrical prosthesis, has elongated body delimiting cavity, and reversible cartridge covered with orientation signs characterizing orientation of oriented unit in cartridge
US20210369945A1 (en) * 2018-06-25 2021-12-02 Sanofi Packaging for a medicament container
US11904132B2 (en) * 2018-06-25 2024-02-20 Sanofi Packaging for a medicament container

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