US20030109925A1 - Accommodating intraocular lens - Google Patents
Accommodating intraocular lens Download PDFInfo
- Publication number
- US20030109925A1 US20030109925A1 US10/329,076 US32907602A US2003109925A1 US 20030109925 A1 US20030109925 A1 US 20030109925A1 US 32907602 A US32907602 A US 32907602A US 2003109925 A1 US2003109925 A1 US 2003109925A1
- Authority
- US
- United States
- Prior art keywords
- intraocular lens
- optic
- movement
- region
- enlarged distal
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/14—Eye parts, e.g. lenses, corneal implants; Implanting instruments specially adapted therefor; Artificial eyes
- A61F2/16—Intraocular lenses
- A61F2/1613—Intraocular lenses having special lens configurations, e.g. multipart lenses; having particular optical properties, e.g. pseudo-accommodative lenses, lenses having aberration corrections, diffractive lenses, lenses for variably absorbing electromagnetic radiation, lenses having variable focus
- A61F2/1616—Pseudo-accommodative, e.g. multifocal or enabling monovision
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/14—Eye parts, e.g. lenses, corneal implants; Implanting instruments specially adapted therefor; Artificial eyes
- A61F2/16—Intraocular lenses
- A61F2/1613—Intraocular lenses having special lens configurations, e.g. multipart lenses; having particular optical properties, e.g. pseudo-accommodative lenses, lenses having aberration corrections, diffractive lenses, lenses for variably absorbing electromagnetic radiation, lenses having variable focus
- A61F2/1624—Intraocular lenses having special lens configurations, e.g. multipart lenses; having particular optical properties, e.g. pseudo-accommodative lenses, lenses having aberration corrections, diffractive lenses, lenses for variably absorbing electromagnetic radiation, lenses having variable focus having adjustable focus; power activated variable focus means, e.g. mechanically or electrically by the ciliary muscle or from the outside
- A61F2/1629—Intraocular lenses having special lens configurations, e.g. multipart lenses; having particular optical properties, e.g. pseudo-accommodative lenses, lenses having aberration corrections, diffractive lenses, lenses for variably absorbing electromagnetic radiation, lenses having variable focus having adjustable focus; power activated variable focus means, e.g. mechanically or electrically by the ciliary muscle or from the outside for changing longitudinal position, i.e. along the visual axis when implanted
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/14—Eye parts, e.g. lenses, corneal implants; Implanting instruments specially adapted therefor; Artificial eyes
- A61F2/16—Intraocular lenses
- A61F2/1613—Intraocular lenses having special lens configurations, e.g. multipart lenses; having particular optical properties, e.g. pseudo-accommodative lenses, lenses having aberration corrections, diffractive lenses, lenses for variably absorbing electromagnetic radiation, lenses having variable focus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/14—Eye parts, e.g. lenses, corneal implants; Implanting instruments specially adapted therefor; Artificial eyes
- A61F2/16—Intraocular lenses
- A61F2/1694—Capsular bag spreaders therefor
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29D—PRODUCING PARTICULAR ARTICLES FROM PLASTICS OR FROM SUBSTANCES IN A PLASTIC STATE
- B29D11/00—Producing optical elements, e.g. lenses or prisms
- B29D11/02—Artificial eyes from organic plastic material
- B29D11/023—Implants for natural eyes
- B29D11/026—Comprising more than one lens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/14—Eye parts, e.g. lenses, corneal implants; Implanting instruments specially adapted therefor; Artificial eyes
- A61F2/16—Intraocular lenses
- A61F2/1613—Intraocular lenses having special lens configurations, e.g. multipart lenses; having particular optical properties, e.g. pseudo-accommodative lenses, lenses having aberration corrections, diffractive lenses, lenses for variably absorbing electromagnetic radiation, lenses having variable focus
- A61F2/1648—Multipart lenses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/14—Eye parts, e.g. lenses, corneal implants; Implanting instruments specially adapted therefor; Artificial eyes
- A61F2/16—Intraocular lenses
- A61F2002/1681—Intraocular lenses having supporting structure for lens, e.g. haptics
Definitions
- the present invention relates to intraocular lenses (IOLs). More particularly, the present invention relates to IOLs which are adapted to provide accommodating movement in the eye.
- IOLs intraocular lenses
- the human visual system includes the eyes, the extraocular muscles which control eye position within the eye socket, the optic and other nerves that connect the eyes to the brain, and particular areas of the brain that are in neural communication with the eyes.
- the visual system is particularly well adapted for the rapid and precise extraction of spatial information from a field of view which is accomplished by analyzing the continuously changing patterns of radiant flux impinging upon the surfaces of the eyes.
- Each eye forms an image upon a vast array of light sensitive photoreceptors of the retina.
- the cornea is the primary refracting surface which admits light through the anterior part of the outer surface of the eye.
- the iris contains muscles which alter the size of the entrance port of the eye, or pupil.
- the crystalline lens has a variable shape, under the indirect control of the ciliary muscle. Having a refractive index higher than the surrounding media, the crystalline lens gives the eye a variable focal length, allowing accommodation to objects at varying distances from the eye.
- the aqueous humor fills the anterior chamber between the cornea and the iris
- the vitreous humor fills the majority of the volume of the eye in the vitreous chamber.
- the crystalline lens is contained within a third chamber of the eye, the posterior chamber, which is positioned between the anterior and vitreous chambers.
- the human eye is susceptible to a score or more of disorders and diseases, a number of which attack the crystalline lens. For example, cataracts mar vision through cloudy or opaque discoloration of the lens of the eye. Cataracts often result in partial or complete blindness. If this is the case, the crystalline lens can be removed and replace with an intraocular lens, or IOL.
- IOL intraocular lens
- IOLs While restoring vision, conventional IOLs have limited ability for accommodation (i.e., the focusing on near objects). This condition is known as presbyopia.
- presbyopia To overcome presbyopia of an IOL, a patient may be prescribed eyeglasses.
- IOLs intraocular lenses
- the present IOLs provide effective accommodation using one or more optics.
- the IOLs of the invention also inhibit cell growth, particularly epithelial cell growth, onto the optics of the IOLs.
- the IOLs of the present invention are configured, and preferably promote cellular and fibrous growth to desired regions of the IOL, to increase the amount of force exerted by the eye against the IOLs to increase the amount of accommodation achieved.
- the present IOLs are relatively straightforward in design, can be produced using conventional IOL manufacturing procedures and can be inserted or implanted in eyes, e.g., human eyes, using surgical techniques which are the same as or analogous to such techniques used with conventional IOLs.
- an intraocular lens which includes an optic for focusing light on a retina and a movement assembly coupled to the optic.
- the movement assembly is adapted to cooperate with the eye to effect accommodating movement of the optic.
- the movement assembly includes a movement member with a proximal region coupled to the optic.
- the movement member, and in particular the proximal region of the movement member extends radially outwardly from the optic and includes an enlarged distal region with a contact surface adapted to be in contact with a peripheral region of a capsular bag of an eye.
- the IOL is held within, preferably attached to, the capsular bag. More specifically, the contact surface of the enlarged distal region may have an axial length of at least about 1 mm. Therefore, depending upon the radius of the IOL, the contact surface has a relatively large surface area with which to contact the capsular bag.
- the contact of the IOL with the capsular bag is further enhanced by disposing the enlarged distal region in an angled manner relative to the proximal region of the member.
- the contact surface is substantially parallel to the optical axis of the IOL.
- the relatively large contact surface is effective in maintaining the position of the IOL particularly directly following implantation and, on a long term basis, is effective in increasing the amount of accommodation provided by the IOL.
- the relatively large surface area of the contact surface also promotes cellular and fibrous growth to or onto this region of the IOL, which further holds and retains the IOL within the capsular bag and increases the amount of force that may be exerted through the capsular bag onto the IOL to provide accommodation, as desired.
- Post-operative cellular and fibrous growth of the interior of the capsular bag to the enlarged distal region of the movement assembly may, and preferably does, enable the IOLs of the present invention to function substantially analogous to a natural crystalline lens.
- the enlarged distal region may include a plurality of depressions or through holes.
- Each of the through holes preferably provides increased growth of cells and fibrin onto the enlarged distal region or regions of the IOL.
- the IOL is very effectively attachable, preferably substantially permanently attachable, to the capsular bag. This attachment of the IOL to the capsular bag facilitates the axial movement of the IOL in direct response to changes in the capsular bag, therefore providing effective accommodation, analogous to a natural crystalline lens.
- the IOLs of the present invention preferably inhibit unwanted posterior capsule opacification (PCO) of the optic.
- PCO posterior capsule opacification
- the distal region or regions of the movement assembly preferably is or are joined to the proximal region or regions so that one or more sharp edges, that is preferably edges which occur at discontinuities (rather than at smooth, continuous transitions) when viewed by the is naked human eye, are present between the joined proximal and distal regions.
- Such sharp edges have been found to advantageously inhibit PCO by inhibiting the growth of cells, for example, epithelial cells, from the capsular bag onto the optic of the present IOLs.
- the movement assembly preferably is positioned relative to the optic so that, with the IOL at rest, that is with no forces acting on the IOL to effect accommodation, the proximal region of the movement member is positioned at an angle other than 90° relative to the central optical axis of the optic.
- the optic in the rest position as noted above, is anteriorly vaulted.
- the movement member or members preferably include a hinge, or a plurality of hinges, located on the proximal region or regions of the movement members, more preferably closer to the optic than to the distal region or regions.
- the movement assembly includes a plurality of movement members, preferably spaced apart, for example, radially or circumferentially spaced apart, from each other.
- Each movement member includes a proximal region coupled to the optic and an enlarged distal region, for example, as described elsewhere herein.
- the enlarged distal regions each have a contact surface adapted to be in contact with a peripheral region of a capsular bag of an eye.
- the enlarged distal regions may be configured such that the contact surfaces are substantially coaxial with the optical axis of the optic.
- a plurality of spacer or cut-out regions preferably are located between radially or circumferentially adjacent movement members. Such cut-out regions are effective to prevent buckling of the IOL during accommodating movement in the eye. Such spacers or cut-out regions may be open. In one useful embodiment each of such regions is at least partially covered with or by a structural material having increased flexibility relative to the movement members. Thus, the IOL is prevented from buckling while, at the same time the structural material is effective to at least inhibit cell growth from the capsular bag onto the optic.
- This structural material may have the same chemical make-up as the proximal regions of the movement members and have a reduced thickness relative to the proximal regions to provide the increased flexibility.
- the secondary optic may be coupled to the enlarged distal region or regions with one or more secondary movement members.
- the enlarged distal region or regions of the movement member or members are provided with a groove or grooves.
- the secondary movement member or members are adapted to fit into the groove or grooves, thereby holding the second optic in position in the eye.
- the second optic and secondary movement members may be formed integrally with the optic/movement assembly combination.
- an intraocular lens comprises a plurality of arcuate segments mechanically coupled (e.g., adhered) to an integrally formed optic and radially outward movement members.
- the arcuate segments may have one or more grooves for receiving one or more movement members, thus forming either a one-optic or a two-optic system.
- the second optic preferably has an optical power, or even substantially no optical power.
- the combination of the optic and second optic together preferably provides the optical power required or desired by the patient in whose eye the IOL is to be implanted.
- the second optic can have a plano or substantially plano optical power or a relatively highly negative optical power, for example, between about ⁇ 30 diopters to about ⁇ 10 diopters, as desired.
- the second optic preferably is located posterior of the optic.
- the second optic, in the eye is substantially maintained in contact with the inner posterior wall of the capsular bag. This feature inhibits or reduces the risk of cell growth or migration from the capsular bag into the second optic.
- the second optic in such a posterior position often has only a relatively restricted, if any, amount of axial movement.
- a posterior second optic preferably is posteriorly vaulted, with the IOL in the rest position as described elsewhere herein, to facilitate maintaining the posterior face of the second optic in contact with the inner posterior face of the capsular bag.
- FIG. 1 is a perspective of an intraocular lens (IOL) according to an exemplary embodiment of the present invention, particularly illustrating an anterior side of the IOL.
- IOL intraocular lens
- FIG. 2 is a fragmentary cross-sectional view of an eye in which an IOL configured in accordance with the present invention has been implanted.
- FIG. 3 is a plan view of an intraocular lens (IOL) of the invention, particularly illustrating a posterior side of the IOL.
- IOL intraocular lens
- FIG. 4 is a plan view of an alternate embodiment of an intraocular lens (IOL) of the invention, illustrating the use of flexible structural material between movement members.
- IOL intraocular lens
- FIG. 5 is an enlarged view of a two-lens system and a circumferential groove for receiving and retaining a posterior lens.
- FIG. 6 is a plan view of and alternative embodiment of an intraocular lens (IOL) of the invention constructed of mechanically coupled lens and peripheral regions.
- IOL intraocular lens
- FIG. 7A is a plan view of one segment of a peripheral region of the IOL of FIG. 6.
- FIG. 7B is an elevational view of the peripheral region segment of FIG. 7A.
- FIG. 7C is an enlarged view of a portion of FIG. 7B.
- FIG. 8 is a perspective view of a ring formed during the process of making the peripheral region of the IOL of FIG. 6.
- an intraocular lens (IOL) 10 according to an exemplary embodiment of the present invention is illustrated in FIG. 1.
- IOL 10 includes an optic 12 and a movement assembly 14 coupled to the optic 12 .
- the optic 12 which has an optical axis O, is adapted to focus light on a retina of an eye.
- the movement assembly 14 of exemplary IOL 10 is adapted to cooperate with an eye to effect accommodating movement of the optic 12 , which is discussed in detail below.
- Exemplary movement assembly 14 includes a member 16 with a proximal region 18 and an enlarged distal region 20 .
- the terms “proximal” and “distal” are used herein with respect to the distance from the optical axis O.
- the proximal region 18 is coupled to the optic 12 at a periphery 22 of the optic.
- the member 16 extends radially outwardly from the optic 12 and the proximal region 18 to the enlarged distal region 20 .
- the enlarged distal region 20 has a contact surface 24 which is adapted to be in contact with a peripheral region 26 of a capsular bag 28 of an eye 30 .
- the capsular bag 28 is connected to a ciliary muscle 32 by suspensory ligaments or zonules 34 .
- the ciliary muscle 32 is the prime mover in accommodation, i.e., in adjusting the eye 30 to focus on near objects.
- the zonules 34 retain the lens in position and are relaxed by the contraction of the ciliary muscle 32 , thereby allowing a natural crystalline lens to become more convex.
- exemplary IOL 10 is configured to facilitate movement of the optic 12 in response to the action of the ciliary muscle 32 and the zonules 34 .
- the ciliary muscle 32 contracts, and the zonules 34 relax and reduce the equatorial diameter of the capsular bag 28 , thereby moving the optic 12 anteriorly as indicated by arrow A in FIG. 2.
- This anterior movement of the optic 12 increases or amplifies the amount of positive (i.e., near) accommodation of the optic 12 .
- the zonules 34 constrict and increase the equatorial diameter of the capsular bag 28 , thus moving the optic posteriorly as indicated by arrow P.
- exemplary IOL 10 may be configured such that the amount of positive or near accommodation is preferably at least about 1 diopter and may range up to 3.5 diopters or more. Further, exemplary IOL 10 may be configured to provide at least about 1.5 mm or 2 mm of axial movement anteriorly in the eye with about a reduction of about 1 mm in the equatorial diameter of the capsular bag 28 caused by the ciliary muscle 32 and the zonules 34 .
- the enlarged distal region 20 of the movement assembly 14 is adapted to be in contact with the peripheral region 26 of the capsular bag 28 .
- the contact surface 24 of the enlarged distal region 20 has a relatively large surface area. In other words, it is preferable to maximize the surface area of the contact surface 24 while maintaining the ability of the IOL 10 to be received within the capsular bag 28 .
- the IOL 10 of the present invention effectively responds to changes in force exerted by the capsular bag 26 on the lens 10 , thereby maximizing axial movement of the optic 12 .
- the contact surface 24 of the enlarged distal region 20 also provides a large surface area to be subject to cellular and fibrous growth, which will be discussed in more detail below.
- the enlarged distal region 20 may be described as a plurality of peripheral arcuate bands with the contact surface 24 comprising the distal surface of each band.
- Each of the arcuate bands of the enlarged distal region 20 extends axially and has a length l, which will be discussed in more detail below.
- Each of the enlarged distal regions 20 may extend axially in a substantially parallel relationship with the optical axis O or, alternatively, may be arcuate in the axial direction such that the length l is an arc length ⁇ (both symbols illustrated in FIG. 1 on one of the contact surfaces 24 ).
- the movement assembly 14 may include a plurality of cut-out regions 36 (e.g., four), thereby defining a corresponding plurality of spokes or haptic members 38 .
- Each of the haptic members 38 includes a respective portion of the enlarged distal region 20 of the member 16 of the assembly 14 .
- the cut-out regions 36 provide spatial relief when the ciliary muscle 32 contracts, thereby preventing buckling of the optic 12 during accommodation.
- PCO posterior capsule opacification
- each of the cut-out regions 36 may be filled with the same material from which the optic 12 is made.
- the haptic members 38 as shown in the exemplary embodiment of FIG. 1 may be substantially flat in configuration, flaring outwardly like pieces of a pie.
- the haptic members 38 desirably lie in planes angled with respect to the optical axis O to promote anterior movement, as further explained below.
- it is preferable to include four haptic members 38 such that each haptic member 38 may extend through nearly 90°, which extent is dependent upon the size of the cut-out regions 36 .
- the haptic members 38 of exemplary movement assembly 14 may be angulated such that the optic 12 is positioned anterior to respective intersections 40 of the haptic members 38 and the enlarged distal regions 20 , which is particularly shown in FIG. 2.
- this angled configuration of the haptic members 38 is called “anterior angulation.”
- the movement assembly 14 is biased to move the optic 12 toward the anterior of the eye 30 when the ciliary muscle 32 contracts.
- the anterior angulation of the haptic members 38 ensures that the optic 12 moves in the anterior direction when the ciliary muscle 32 contracts.
- each of the haptic members 38 with a groove 41 formed in a posterior side thereof.
- the grooves 41 define an area of reduced thickness of each haptic member 38 , thereby biasing the haptic members 38 to flex or pivot at the grooves 41 .
- the grooves 41 accommodate flexing of the haptic members 38 in the anterior direction.
- the grooves 41 may be arcuate and concentric with respective contact surfaces 24 .
- Axial movement may be further facilitated by providing a hinge 42 at the interior intersection 40 of each haptic member 38 with the respective portion of the enlarged distal region 20 .
- the hinges 42 enhance the pivoting of the haptic members 38 relative to the enlarged distal region 20 when the ciliary muscle 32 contracts.
- each hinge 42 may be configured as a discontinuity, preferably a sharp edge, to retard or prevent cellular growth onto the haptic members 38 and the optic 12 , thereby preventing PCO.
- each of the contact surfaces 24 of the enlarged distal region 20 has a large surface area, thereby providing a large surface area subject to cellular and fibrous growth.
- each of the contact surfaces 24 of the enlarged distal region 20 may have an axial length l (or arcuate span ⁇ ) of at least about 1 mm and preferably on the order of about 2 mm. Therefore, depending upon the radius of the IOL 10 , each of the contact surfaces 24 may have a surface area of the product of the axial length l and the arc length a.
- Post-operative cellular and fibrous growth of the interior of the capsular bag 28 to the enlarged distal region 20 of the movement assembly 14 enables the IOL 10 of the present invention to essentially fully function like a natural crystalline lens.
- the cellular and fibrous growth is facilitated by the close proximity of the contact surface 24 with the capsular bag 28 .
- the enlarged distal region 20 may include a plurality of depressions or holes 44 .
- Each of the holes 44 provides a purchase on which cells and fibrin may grow. It is anticipated that this cellular and fibrous growth may take place within the first few weeks after the IOL 10 is implanted in an eye. Accordingly, the IOL 10 is permanently attachable to the capsular bag 28 . This vigorous attachment of the IOL 10 to the capsular bag 28 ensures that the IOL 10 moves axially in direct response to changes in the capsular bag 28 , therefore accommodating near vision, analogous to that of a natural crystalline lens.
- the IOL 10 of the present invention may be configured as a two-optic IOL. More specifically, exemplary IOL 10 may include a secondary optic 46 coupled to a secondary member 48 . Analogous to member 16 described above, the secondary member 48 may include a proximal region coupled to the secondary optic 46 and a distal region, which distal region is either the enlarged distal region 20 described above, or a separate enlarged distal region, as indicated in the region 49 . Further, the plurality of cut-out regions 36 may extend through the secondary member 48 , thereby defining a plurality of secondary haptic members 50 .
- the secondary member 48 with secondary optic 46 may be integral with the enlarged distal region 20 or, alternatively, may be mechanically attached to the enlarged distal region 20 or member 16 to function as an auxiliary IOL.
- the enlarged distal region 20 of the first movement member 10 is provided with a groove or channel (not shown). The secondary movement member 48 is adapted to fit into the groove, thereby holding the second optic 46 in position in the eye.
- the distal regions 49 of the secondary haptic members 50 may be adapted to attach to or be retained by the movement assembly 14 of the IOL 10 .
- a groove may be formed either on a posterior side of member 16 or, alternatively, on an interior side of the enlarged distal region 24 .
- the latter type of groove is seen at 52 in FIG. 5.
- the groove 52 is sized so that ends of the distal regions 49 of the secondary haptic members 50 are receivable therein.
- the distal regions 49 may be permanently received within the groove 52 such as with adhesive or, alternatively, releasably received so that the secondary optic 46 may be replaced if needed or desired.
- secondary haptic members 50 are angulated such that the secondary optic 46 is positioned posterior to respective intersections of the haptic members and the enlarged distal regions 20 , which is particularly shown in FIG. 2.
- this angled configuration of the secondary haptic members 50 will be called “posterior angulation.”
- each of the plurality of cut-out regions 36 in the secondary member 48 is at least partially filled with or covered by a structural material 51 having increased flexibility relative to the movement member.
- a structural material 51 having increased flexibility relative to the movement member.
- the second IOL is prevented from buckling while, at the same time the structural material 51 is effective to at least inhibit cell growth from the capsular bag onto the optic.
- This structural material 51 may have the same chemical make-up as the proximal regions of the movement members and have a reduced thickness relative to the proximal regions to provide the increased flexibility.
- the cut-out regions 36 may be filled with the same material from which the optic 46 is made.
- FIG. 6 illustrates an alternative embodiment of the present invention in which an intraocular lens (IOL) 60 comprises an inner lens portion mechanically coupled to an outer peripheral region 62 .
- the inner lens portion is shown in phantom and includes an optic 64 and a plurality of movement members 66 extending radially outwardly therefrom. As with the earlier embodiments, there are four such movement members 66 extending radially outward evenly about the optic 64 , and each defining an included angle of nearly 90°.
- the outer peripheral region 62 comprises a plurality of individual arcuate segments 62 a - d disposed around the periphery of the IOL and each mechanically coupled to a movement member 66 .
- the movement member 66 are substantially pie-shaped and each of the arcuate segments 62 has a length that matches the outer circumferential arc of the respectively coupled movement member.
- the included angle of each movement member 66 and coupled peripheral segment 62 is less than 90° so that cut-outs or spacer regions 68 are defined therebetween.
- the arc of the each segment 62 is desirably centered at the optical axis of the optic 64 .
- the spacer regions 68 each extend from the peripheral region 62 to the optic 64 , and terminate at a radially inner curved end.
- each of the arcuate segments 62 defines an included angle ⁇ of between 70-85°, and more particularly about 78°. Consequently, the angle ⁇ defined between the segments is between about 5-20 20 , and more particularly about 12°.
- the exemplary embodiment has an outer radius r o of about 5.27 mm (0.2075 inches) and an inner radius r i of about 4.76 mm (0.187 inches).
- each of the arcuate segments 62 includes a rounded outer surface 70 and a pair of grooves 72 a and 72 b defined on the inner surface.
- Each groove 72 is defined by a side wall 74 , and a peripheral wall 76 .
- the side walls 74 of the two grooves diverge but generally face each other, and the peripheral walls 76 are angled with respect one another and meet at an apex 78 , desirably at the axial midplane of the segment 62 .
- each arcuate segment 62 is about 1.02 mm (0.04 inches), while the outer peripheral radius r p is desirably about the same as the thickness t, namely about 1.02 mm (0.04 inches).
- the overall radial thickness A of each segment 62 is about 0.51 mm (0.02 inches), while the radial depth B of each of the grooves 72 is about 0.23 mm (0.009 inches).
- the axial width w of the two grooves 72 together is about 0.51 mm (0.02 inches), and the peripheral surface 76 of each groove defines an angle ⁇ of about 10° at any one point with respect to a plane tangent to the entire arcuate segment 62 at that point. Finally, the included angle ⁇ defined by the divergent side walls 74 of the two grooves 72 is about 20°.
- each arcuate segment 62 receives movement members 66 extending outward from two different optics 64 .
- FIG. 7C illustrates two movement members 66 a and 66 b disposed, respectively, within the grooves 72 a and 72 b and diverging at the included angle ⁇ of the side walls 74 .
- one of the optics is anteriorly vaulted and the other optic is posteriorly vaulted.
- the two movement members 66 a,b are desirably sized to precisely fit within grooves 72 a,b and contact at juxtaposed corners coincident with the apex 78 .
- the resulting two-optic system can be customized to suit a wide variety of patient needs.
- the segments 62 a - d are formed from a circular ring 80 as seen in FIG. 8.
- the ring 80 is molded using conventional means, and the segments 62 are then machined therefrom. Subsequently, the segments 62 are mechanically coupled to the respective movement members 66 using a suitable adhesive, or the like.
- a suitable adhesive or the like.
- the IOL 60 has the benefit of an enlarged outer peripheral region 62 which helps distribute forces imparted by the ciliary muscles to the movement members 66 , and thereafter to the optic 64 . Such a force distribution system helps improve accommodation of the IOL 60 .
- the optics 12 and 46 may be constructed of rigid biocompatible materials such as polymethyl methacrylate (PMMA) or deformable materials such as silicone polymeric materials, acrylic polymeric materials, hydrogel polymeric materials, and the like.
- PMMA polymethyl methacrylate
- deformable materials such as silicone polymeric materials, acrylic polymeric materials, hydrogel polymeric materials, and the like.
- the deformable materials allow the IOL 10 to be rolled or folded for insertion through a small incision into the eye.
- the optic 12 as shown is a refractive lens body
- the present IOLs may include a diffractive lens body, and such embodiment is included within the scope of the present invention.
- the optic 12 may be either integral with or mechanically coupled to the member 16 .
- the member 16 may be constructed of the same or different biocompatible materials as the optic 12 , and is preferably made of polymeric materials such as polypropylene, silicone polymeric materials, acrylic polymeric materials, and the like.
- the movement assembly 14 is preferably deformable in much the same manner as the optic 12 to facilitate the passage of the IOL 10 through a small incision into the eye.
- the material or materials of construction from which the movement assembly 14 is made are chosen to provide the assembly with the desired mechanical properties, e.g., strength and deformability, to meet the needs of the particular application involved.
- the IOL 10 may be inserted into the capsular bag 28 of a mammalian eye using conventional equipment and techniques, for example, after the natural crystalline lens is removed using a phaceomulsification technique.
- the IOL 10 is preferably rolled or folded prior to insertion into the eye so as to fit through a small incision, for example, on the order of about 3.2 mm. After insertion, the IOL 10 may be positioned in the eye as shown in FIG. 2.
- the optic 12 preferably has a diameter in the range of about 3.5 mm to about 7 mm and, more preferably, in the range of about 5 mm to about 6 mm. Further, the IOL 10 may have an overall diameter, with the movement assembly 14 in an unstressed condition, of about 8 mm to about 11 mm or 12 mm. Additionally, the optic 12 preferably has a far-vision correction power for infinity in an accommodated state.
- the present invention provides accommodating IOLs and methods for using such IOLs.
- the IOLs of the invention are configured to reduce the stretching of the capsular bag, to maintain the elasticity and/or integrity of the capsular bag, to enhance the effectiveness of the eye, particularly the function of the ciliary muscle and the zonules.
- the present IOLs promote the secure retention within the capsular bag by providing an enlarged contact surface to which cells and fibrin may grow.
- the present IOLs inhibit PCO.
Landscapes
- Health & Medical Sciences (AREA)
- Ophthalmology & Optometry (AREA)
- Engineering & Computer Science (AREA)
- Vascular Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Transplantation (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Manufacturing & Machinery (AREA)
- Mechanical Engineering (AREA)
- Prostheses (AREA)
- Materials For Medical Uses (AREA)
Abstract
An intraocular lens includes an optic for focusing light and a movement assembly coupled to the optic. The movement assembly is adapted to cooperate with the eye to effect accommodating movement of the optic. The movement assembly includes a plurality of movement members each with a proximal region coupled to the optic and an enlarged distal region. The enlarged distal region may be integral with the proximal region, or may be mechanically coupled thereto.
Description
- The present invention relates to intraocular lenses (IOLs). More particularly, the present invention relates to IOLs which are adapted to provide accommodating movement in the eye.
- The human visual system includes the eyes, the extraocular muscles which control eye position within the eye socket, the optic and other nerves that connect the eyes to the brain, and particular areas of the brain that are in neural communication with the eyes. The visual system is particularly well adapted for the rapid and precise extraction of spatial information from a field of view which is accomplished by analyzing the continuously changing patterns of radiant flux impinging upon the surfaces of the eyes.
- Image formation is greatly complicated by the movement of the eyes within the head, as well as by the movement of both eyes and the head relative to the external sea of radiant energy. Visual input is ordinarily sampled by discrete momentary pauses of the eyes called fixations, interrupted by very rapid ballistic motions known as saccades which bring the eye from one fixation position to the next. Smooth movements of the eyes can occur when an object having a predictable motion is available to be followed.
- Each eye forms an image upon a vast array of light sensitive photoreceptors of the retina. The cornea is the primary refracting surface which admits light through the anterior part of the outer surface of the eye. The iris contains muscles which alter the size of the entrance port of the eye, or pupil. The crystalline lens has a variable shape, under the indirect control of the ciliary muscle. Having a refractive index higher than the surrounding media, the crystalline lens gives the eye a variable focal length, allowing accommodation to objects at varying distances from the eye.
- Much of the remainder of the eye is filled with fluids and materials under pressure which help the eye maintain its shape. For example, the aqueous humor fills the anterior chamber between the cornea and the iris, and the vitreous humor fills the majority of the volume of the eye in the vitreous chamber. The crystalline lens is contained within a third chamber of the eye, the posterior chamber, which is positioned between the anterior and vitreous chambers.
- The human eye is susceptible to a score or more of disorders and diseases, a number of which attack the crystalline lens. For example, cataracts mar vision through cloudy or opaque discoloration of the lens of the eye. Cataracts often result in partial or complete blindness. If this is the case, the crystalline lens can be removed and replace with an intraocular lens, or IOL.
- While restoring vision, conventional IOLs have limited ability for accommodation (i.e., the focusing on near objects). This condition is known as presbyopia. To overcome presbyopia of an IOL, a patient may be prescribed eyeglasses. Alternative attempts in the art to overcome presbyopia focus on providing IOLs with accommodation ability. Accommodation may be accomplished by either changing the shape of the IOL, e.g., to become more convex to focus on near objects, or by moving the IOL along its optical axis. For example, a number of these approaches bias an IOL to be located in the most posterior position of the posterior chamber of the eye under rest conditions. When near focus is required, the ciliary muscle contracts, and the IOL moves forwardly, which is known as positive accommodation. In the absence of ciliary muscle contraction, the IOL is biased rearwardly to the most posterior position. While these approaches may provide limited accommodation, the posterior bias and the configuration of the IOL prevent sufficient forward axial movement required for full-range accommodation.
- In view of the foregoing, it would be beneficial in the art to provide IOLs adapted for sufficient accommodation to reduce significantly or to overcome the effects of presbyopia.
- New intraocular lenses (IOLs) effective to provide accommodation have been discovered. The present IOLs provide effective accommodation using one or more optics. The IOLs of the invention also inhibit cell growth, particularly epithelial cell growth, onto the optics of the IOLs. The IOLs of the present invention are configured, and preferably promote cellular and fibrous growth to desired regions of the IOL, to increase the amount of force exerted by the eye against the IOLs to increase the amount of accommodation achieved. The present IOLs are relatively straightforward in design, can be produced using conventional IOL manufacturing procedures and can be inserted or implanted in eyes, e.g., human eyes, using surgical techniques which are the same as or analogous to such techniques used with conventional IOLs.
- According to one aspect of the invention, an intraocular lens is provided which includes an optic for focusing light on a retina and a movement assembly coupled to the optic. The movement assembly is adapted to cooperate with the eye to effect accommodating movement of the optic. The movement assembly includes a movement member with a proximal region coupled to the optic. The movement member, and in particular the proximal region of the movement member, extends radially outwardly from the optic and includes an enlarged distal region with a contact surface adapted to be in contact with a peripheral region of a capsular bag of an eye.
- One of the advantages of the present invention is that the IOL is held within, preferably attached to, the capsular bag. More specifically, the contact surface of the enlarged distal region may have an axial length of at least about 1 mm. Therefore, depending upon the radius of the IOL, the contact surface has a relatively large surface area with which to contact the capsular bag.
- The contact of the IOL with the capsular bag is further enhanced by disposing the enlarged distal region in an angled manner relative to the proximal region of the member. Preferably, the contact surface is substantially parallel to the optical axis of the IOL. The relatively large contact surface is effective in maintaining the position of the IOL particularly directly following implantation and, on a long term basis, is effective in increasing the amount of accommodation provided by the IOL.
- The relatively large surface area of the contact surface also promotes cellular and fibrous growth to or onto this region of the IOL, which further holds and retains the IOL within the capsular bag and increases the amount of force that may be exerted through the capsular bag onto the IOL to provide accommodation, as desired. Post-operative cellular and fibrous growth of the interior of the capsular bag to the enlarged distal region of the movement assembly may, and preferably does, enable the IOLs of the present invention to function substantially analogous to a natural crystalline lens.
- To further facilitate this post-operative cellular growth, the enlarged distal region may include a plurality of depressions or through holes. Each of the through holes preferably provides increased growth of cells and fibrin onto the enlarged distal region or regions of the IOL. Accordingly, the IOL is very effectively attachable, preferably substantially permanently attachable, to the capsular bag. This attachment of the IOL to the capsular bag facilitates the axial movement of the IOL in direct response to changes in the capsular bag, therefore providing effective accommodation, analogous to a natural crystalline lens.
- The IOLs of the present invention preferably inhibit unwanted posterior capsule opacification (PCO) of the optic. Thus, the distal region or regions of the movement assembly preferably is or are joined to the proximal region or regions so that one or more sharp edges, that is preferably edges which occur at discontinuities (rather than at smooth, continuous transitions) when viewed by the is naked human eye, are present between the joined proximal and distal regions. Such sharp edges have been found to advantageously inhibit PCO by inhibiting the growth of cells, for example, epithelial cells, from the capsular bag onto the optic of the present IOLs.
- To further enhance the accommodating movement of the present IOLs in cooperation with the eye, the movement assembly preferably is positioned relative to the optic so that, with the IOL at rest, that is with no forces acting on the IOL to effect accommodation, the proximal region of the movement member is positioned at an angle other than 90° relative to the central optical axis of the optic. In a very useful embodiment, the optic, in the rest position as noted above, is anteriorly vaulted. Also, the movement member or members preferably include a hinge, or a plurality of hinges, located on the proximal region or regions of the movement members, more preferably closer to the optic than to the distal region or regions. Each of these features, either individually or any combination thereof, is effective to further facilitate the movement of the optic to provide the desired amount of accommodation.
- According to another aspect of the invention, the movement assembly includes a plurality of movement members, preferably spaced apart, for example, radially or circumferentially spaced apart, from each other. Each movement member includes a proximal region coupled to the optic and an enlarged distal region, for example, as described elsewhere herein. The enlarged distal regions each have a contact surface adapted to be in contact with a peripheral region of a capsular bag of an eye. In addition, the enlarged distal regions may be configured such that the contact surfaces are substantially coaxial with the optical axis of the optic.
- A plurality of spacer or cut-out regions preferably are located between radially or circumferentially adjacent movement members. Such cut-out regions are effective to prevent buckling of the IOL during accommodating movement in the eye. Such spacers or cut-out regions may be open. In one useful embodiment each of such regions is at least partially covered with or by a structural material having increased flexibility relative to the movement members. Thus, the IOL is prevented from buckling while, at the same time the structural material is effective to at least inhibit cell growth from the capsular bag onto the optic. This structural material may have the same chemical make-up as the proximal regions of the movement members and have a reduced thickness relative to the proximal regions to provide the increased flexibility.
- Another advantage of the present IOLs is that a second optic may be provided. According to this multi-optic embodiment, the secondary optic may be coupled to the enlarged distal region or regions with one or more secondary movement members.
- In one useful embodiment, the enlarged distal region or regions of the movement member or members are provided with a groove or grooves. The secondary movement member or members are adapted to fit into the groove or grooves, thereby holding the second optic in position in the eye. Alternately, the second optic and secondary movement members may be formed integrally with the optic/movement assembly combination.
- In a further useful embodiment of present invention, the enlarged distal region or regions of the movement member or members are mechanically coupled to the perspective proximal regions. In one particular embodiment, an intraocular lens comprises a plurality of arcuate segments mechanically coupled (e.g., adhered) to an integrally formed optic and radially outward movement members. The arcuate segments may have one or more grooves for receiving one or more movement members, thus forming either a one-optic or a two-optic system.
- The second optic preferably has an optical power, or even substantially no optical power. The combination of the optic and second optic together preferably provides the optical power required or desired by the patient in whose eye the IOL is to be implanted. For example, the second optic can have a plano or substantially plano optical power or a relatively highly negative optical power, for example, between about −30 diopters to about −10 diopters, as desired. The second optic preferably is located posterior of the optic. In one useful embodiment, the second optic, in the eye, is substantially maintained in contact with the inner posterior wall of the capsular bag. This feature inhibits or reduces the risk of cell growth or migration from the capsular bag into the second optic. The second optic in such a posterior position often has only a relatively restricted, if any, amount of axial movement. Such a posterior second optic preferably is posteriorly vaulted, with the IOL in the rest position as described elsewhere herein, to facilitate maintaining the posterior face of the second optic in contact with the inner posterior face of the capsular bag.
- Any and all of the features described herein and combinations of such features are included within the scope of the present invention provided that the features of any such combination are not mutually inconsistent.
- Additional aspects, features, and advantages of the present invention are set forth in the following description and claims, particularly when considered in conjunction with the accompanying drawings in which like parts bear like reference numbers.
- FIG. 1 is a perspective of an intraocular lens (IOL) according to an exemplary embodiment of the present invention, particularly illustrating an anterior side of the IOL.
- FIG. 2 is a fragmentary cross-sectional view of an eye in which an IOL configured in accordance with the present invention has been implanted.
- FIG. 3 is a plan view of an intraocular lens (IOL) of the invention, particularly illustrating a posterior side of the IOL.
- FIG. 4 is a plan view of an alternate embodiment of an intraocular lens (IOL) of the invention, illustrating the use of flexible structural material between movement members.
- FIG. 5 is an enlarged view of a two-lens system and a circumferential groove for receiving and retaining a posterior lens.
- FIG. 6 is a plan view of and alternative embodiment of an intraocular lens (IOL) of the invention constructed of mechanically coupled lens and peripheral regions.
- FIG. 7A is a plan view of one segment of a peripheral region of the IOL of FIG. 6.
- FIG. 7B is an elevational view of the peripheral region segment of FIG. 7A.
- FIG. 7C is an enlarged view of a portion of FIG. 7B.
- FIG. 8 is a perspective view of a ring formed during the process of making the peripheral region of the IOL of FIG. 6.
- Referring to the drawings in more detail, an intraocular lens (IOL)10 according to an exemplary embodiment of the present invention is illustrated in FIG. 1.
Exemplary IOL 10 includes an optic 12 and amovement assembly 14 coupled to the optic 12. The optic 12, which has an optical axis O, is adapted to focus light on a retina of an eye. Themovement assembly 14 ofexemplary IOL 10 is adapted to cooperate with an eye to effect accommodating movement of the optic 12, which is discussed in detail below. -
Exemplary movement assembly 14 includes amember 16 with a proximal region 18 and an enlargeddistal region 20. The terms “proximal” and “distal” are used herein with respect to the distance from the optical axis O. The proximal region 18 is coupled to the optic 12 at aperiphery 22 of the optic. Themember 16 extends radially outwardly from the optic 12 and the proximal region 18 to the enlargeddistal region 20. With additional reference to FIG. 2, the enlargeddistal region 20 has acontact surface 24 which is adapted to be in contact with aperipheral region 26 of acapsular bag 28 of aneye 30. - Briefly describing the anatomy of the
eye 30 with reference to FIG. 2, thecapsular bag 28 is connected to aciliary muscle 32 by suspensory ligaments orzonules 34. Theciliary muscle 32 is the prime mover in accommodation, i.e., in adjusting theeye 30 to focus on near objects. Thezonules 34 retain the lens in position and are relaxed by the contraction of theciliary muscle 32, thereby allowing a natural crystalline lens to become more convex. - Applying this anatomy to the present invention,
exemplary IOL 10 is configured to facilitate movement of the optic 12 in response to the action of theciliary muscle 32 and thezonules 34. When near vision is needed, theciliary muscle 32 contracts, and thezonules 34 relax and reduce the equatorial diameter of thecapsular bag 28, thereby moving the optic 12 anteriorly as indicated by arrow A in FIG. 2. This anterior movement of the optic 12 increases or amplifies the amount of positive (i.e., near) accommodation of the optic 12. Conversely, when theciliary muscle 32 relaxes, thezonules 34 constrict and increase the equatorial diameter of thecapsular bag 28, thus moving the optic posteriorly as indicated by arrow P. - For human implantation,
exemplary IOL 10 may be configured such that the amount of positive or near accommodation is preferably at least about 1 diopter and may range up to 3.5 diopters or more. Further,exemplary IOL 10 may be configured to provide at least about 1.5 mm or 2 mm of axial movement anteriorly in the eye with about a reduction of about 1 mm in the equatorial diameter of thecapsular bag 28 caused by theciliary muscle 32 and thezonules 34. - As mentioned, the enlarged
distal region 20 of themovement assembly 14 is adapted to be in contact with theperipheral region 26 of thecapsular bag 28. In accordance with the invention, thecontact surface 24 of the enlargeddistal region 20 has a relatively large surface area. In other words, it is preferable to maximize the surface area of thecontact surface 24 while maintaining the ability of theIOL 10 to be received within thecapsular bag 28. By maximizing the surface area with which theIOL 10 contacts thecapsular bag 28, theIOL 10 of the present invention effectively responds to changes in force exerted by thecapsular bag 26 on thelens 10, thereby maximizing axial movement of the optic 12. In addition to the advantage of maximizing axial movement, thecontact surface 24 of the enlargeddistal region 20 also provides a large surface area to be subject to cellular and fibrous growth, which will be discussed in more detail below. - According to the exemplary embodiment of the invention shown in FIG. 1, the enlarged
distal region 20 may be described as a plurality of peripheral arcuate bands with thecontact surface 24 comprising the distal surface of each band. Each of the arcuate bands of the enlargeddistal region 20 extends axially and has a length l, which will be discussed in more detail below. Each of the enlargeddistal regions 20 may extend axially in a substantially parallel relationship with the optical axis O or, alternatively, may be arcuate in the axial direction such that the length l is an arc length λ (both symbols illustrated in FIG. 1 on one of the contact surfaces 24). - Regarding
exemplary IOL 10 in more detail, themovement assembly 14 may include a plurality of cut-out regions 36 (e.g., four), thereby defining a corresponding plurality of spokes orhaptic members 38. Each of thehaptic members 38 includes a respective portion of the enlargeddistal region 20 of themember 16 of theassembly 14. The cut-outregions 36 provide spatial relief when theciliary muscle 32 contracts, thereby preventing buckling of the optic 12 during accommodation. To prevent posterior capsule opacification (PCO), each of the cut-outregions 36 may be filled with the same material from which the optic 12 is made. - Regarding the
haptic members 38 in more detail, thehaptic members 38 as shown in the exemplary embodiment of FIG. 1 may be substantially flat in configuration, flaring outwardly like pieces of a pie. Thehaptic members 38 desirably lie in planes angled with respect to the optical axis O to promote anterior movement, as further explained below. As mentioned, it is preferable to include fourhaptic members 38, such that eachhaptic member 38 may extend through nearly 90°, which extent is dependent upon the size of the cut-outregions 36. - To further enhance axial movement and accommodation, the
haptic members 38 ofexemplary movement assembly 14 may be angulated such that the optic 12 is positioned anterior torespective intersections 40 of thehaptic members 38 and the enlargeddistal regions 20, which is particularly shown in FIG. 2. For the purposes of this description, this angled configuration of thehaptic members 38 is called “anterior angulation.” By angulating thehaptic members 38 in this anterior manner, themovement assembly 14 is biased to move the optic 12 toward the anterior of theeye 30 when theciliary muscle 32 contracts. Furthermore, the anterior angulation of thehaptic members 38 ensures that the optic 12 moves in the anterior direction when theciliary muscle 32 contracts. - With continued reference to FIGS. 1 and 2 and additional reference to FIG. 3, accommodation may be further enhanced by providing each of the
haptic members 38 with agroove 41 formed in a posterior side thereof. Thegrooves 41 define an area of reduced thickness of eachhaptic member 38, thereby biasing thehaptic members 38 to flex or pivot at thegrooves 41. With such a construction, thegrooves 41 accommodate flexing of thehaptic members 38 in the anterior direction. As an alternative to the linear embodiment shown in FIG. 3, thegrooves 41 may be arcuate and concentric with respective contact surfaces 24. - Axial movement may be further facilitated by providing a
hinge 42 at theinterior intersection 40 of eachhaptic member 38 with the respective portion of the enlargeddistal region 20. The hinges 42 enhance the pivoting of thehaptic members 38 relative to the enlargeddistal region 20 when theciliary muscle 32 contracts. In addition, each hinge 42 may be configured as a discontinuity, preferably a sharp edge, to retard or prevent cellular growth onto thehaptic members 38 and the optic 12, thereby preventing PCO. - As mentioned above, the
contact surface 24 of the enlargeddistal region 20 has a large surface area, thereby providing a large surface area subject to cellular and fibrous growth. For example, each of the contact surfaces 24 of the enlargeddistal region 20 may have an axial length l (or arcuate span λ) of at least about 1 mm and preferably on the order of about 2 mm. Therefore, depending upon the radius of theIOL 10, each of the contact surfaces 24 may have a surface area of the product of the axial length l and the arc length a. - Contact of the
IOL 10 with thecapsular bag 28 is further enhanced by disposing the enlargeddistal region 20 in a perpendicular manner to thehaptic members 38. Accordingly, thecontact surface 24 is substantially parallel to theoptical axis 10 of theIOL 10. The axial disposition of theenlarged contact surface 24 within thecapsular bag 28 increases the retention of theIOL 10 therewithin, particularly immediately following implantation. - Post-operative cellular and fibrous growth of the interior of the
capsular bag 28 to the enlargeddistal region 20 of themovement assembly 14 enables theIOL 10 of the present invention to essentially fully function like a natural crystalline lens. The cellular and fibrous growth is facilitated by the close proximity of thecontact surface 24 with thecapsular bag 28. - To further facilitate this growth, the enlarged
distal region 20 may include a plurality of depressions or holes 44. Each of theholes 44 provides a purchase on which cells and fibrin may grow. It is anticipated that this cellular and fibrous growth may take place within the first few weeks after theIOL 10 is implanted in an eye. Accordingly, theIOL 10 is permanently attachable to thecapsular bag 28. This vigorous attachment of theIOL 10 to thecapsular bag 28 ensures that theIOL 10 moves axially in direct response to changes in thecapsular bag 28, therefore accommodating near vision, analogous to that of a natural crystalline lens. - With continued reference to FIGS. 2 and 3 and additional reference to FIG. 4, the
IOL 10 of the present invention may be configured as a two-optic IOL. More specifically,exemplary IOL 10 may include asecondary optic 46 coupled to asecondary member 48. Analogous tomember 16 described above, thesecondary member 48 may include a proximal region coupled to thesecondary optic 46 and a distal region, which distal region is either the enlargeddistal region 20 described above, or a separate enlarged distal region, as indicated in theregion 49. Further, the plurality of cut-outregions 36 may extend through thesecondary member 48, thereby defining a plurality of secondaryhaptic members 50. - The
secondary member 48 withsecondary optic 46 may be integral with the enlargeddistal region 20 or, alternatively, may be mechanically attached to the enlargeddistal region 20 ormember 16 to function as an auxiliary IOL. In one useful embodiment, the enlargeddistal region 20 of thefirst movement member 10 is provided with a groove or channel (not shown). Thesecondary movement member 48 is adapted to fit into the groove, thereby holding thesecond optic 46 in position in the eye. - More specifically, the
distal regions 49 of the secondaryhaptic members 50 may be adapted to attach to or be retained by themovement assembly 14 of theIOL 10. For example, a groove may be formed either on a posterior side ofmember 16 or, alternatively, on an interior side of the enlargeddistal region 24. The latter type of groove is seen at 52 in FIG. 5. Thegroove 52 is sized so that ends of thedistal regions 49 of the secondaryhaptic members 50 are receivable therein. Thedistal regions 49 may be permanently received within thegroove 52 such as with adhesive or, alternatively, releasably received so that thesecondary optic 46 may be replaced if needed or desired. - Analogous to the
haptic members 38 described above, secondaryhaptic members 50 are angulated such that thesecondary optic 46 is positioned posterior to respective intersections of the haptic members and the enlargeddistal regions 20, which is particularly shown in FIG. 2. For the purposes of this description, this angled configuration of the secondaryhaptic members 50 will be called “posterior angulation.” By angulating the secondaryhaptic members 50 in this anterior manner, themovement assembly 14 is biased to move thesecondary optic 46 toward the posterior of theeye 30 when theciliary muscle 32 contracts. - In one useful embodiment each of the plurality of cut-out
regions 36 in thesecondary member 48 is at least partially filled with or covered by astructural material 51 having increased flexibility relative to the movement member. Thus, the second IOL is prevented from buckling while, at the same time thestructural material 51 is effective to at least inhibit cell growth from the capsular bag onto the optic. Thisstructural material 51 may have the same chemical make-up as the proximal regions of the movement members and have a reduced thickness relative to the proximal regions to provide the increased flexibility. In particular, the cut-outregions 36 may be filled with the same material from which the optic 46 is made. - FIG. 6 illustrates an alternative embodiment of the present invention in which an intraocular lens (IOL)60 comprises an inner lens portion mechanically coupled to an outer
peripheral region 62. In FIG. 6, the inner lens portion is shown in phantom and includes an optic 64 and a plurality ofmovement members 66 extending radially outwardly therefrom. As with the earlier embodiments, there are foursuch movement members 66 extending radially outward evenly about the optic 64, and each defining an included angle of nearly 90°. - As seen in FIGS. 6 and 7A-C, the outer
peripheral region 62 comprises a plurality of individualarcuate segments 62 a-d disposed around the periphery of the IOL and each mechanically coupled to amovement member 66. In the illustrated embodiment, themovement member 66 are substantially pie-shaped and each of thearcuate segments 62 has a length that matches the outer circumferential arc of the respectively coupled movement member. Desirably, the included angle of eachmovement member 66 and coupledperipheral segment 62 is less than 90° so that cut-outs or spacer regions 68 are defined therebetween. In addition, the arc of the eachsegment 62 is desirably centered at the optical axis of the optic 64. As previously described, the spacer regions 68 each extend from theperipheral region 62 to the optic 64, and terminate at a radially inner curved end. - Various dimensions of each
segment 62 are illustrated in the drawings and exemplary values provided herein. In a preferred embodiment, each of thearcuate segments 62 defines an included angle α of between 70-85°, and more particularly about 78°. Consequently, the angle β defined between the segments is between about 5-2020 , and more particularly about 12°. The exemplary embodiment has an outer radius ro of about 5.27 mm (0.2075 inches) and an inner radius ri of about 4.76 mm (0.187 inches). - With reference particularly to FIGS. 7B and 7C, each of the
arcuate segments 62 includes a roundedouter surface 70 and a pair ofgrooves 72 a and 72 b defined on the inner surface. Each groove 72 is defined by aside wall 74, and aperipheral wall 76. Theside walls 74 of the two grooves diverge but generally face each other, and theperipheral walls 76 are angled with respect one another and meet at an apex 78, desirably at the axial midplane of thesegment 62. - Again, particular dimensions are shown in the drawings, with certain exemplary values provided herein. In particular, the axial thickness t of each
arcuate segment 62 is about 1.02 mm (0.04 inches), while the outer peripheral radius rp is desirably about the same as the thickness t, namely about 1.02 mm (0.04 inches). The overall radial thickness A of eachsegment 62 is about 0.51 mm (0.02 inches), while the radial depth B of each of the grooves 72 is about 0.23 mm (0.009 inches). The axial width w of the two grooves 72 together is about 0.51 mm (0.02 inches), and theperipheral surface 76 of each groove defines an angle γ of about 10° at any one point with respect to a plane tangent to the entirearcuate segment 62 at that point. Finally, the included angle θ defined by thedivergent side walls 74 of the two grooves 72 is about 20°. - Because there are two
grooves 72 a,b, eacharcuate segment 62 receivesmovement members 66 extending outward from twodifferent optics 64. More particularly, FIG. 7C illustrates two movement members 66 a and 66 b disposed, respectively, within thegrooves 72 a and 72 b and diverging at the included angle θ of theside walls 74. In other words, one of the optics is anteriorly vaulted and the other optic is posteriorly vaulted. The two movement members 66 a,b are desirably sized to precisely fit withingrooves 72 a,b and contact at juxtaposed corners coincident with the apex 78. The resulting two-optic system can be customized to suit a wide variety of patient needs. - In a preferred manufacturing process, the
segments 62 a-d are formed from acircular ring 80 as seen in FIG. 8. In particular, thering 80 is molded using conventional means, and thesegments 62 are then machined therefrom. Subsequently, thesegments 62 are mechanically coupled to therespective movement members 66 using a suitable adhesive, or the like. Those of skill in the art will understand that there are various means other than adhesives for attaching movement members to peripheral structures. As a result, theIOL 60 has the benefit of an enlarged outerperipheral region 62 which helps distribute forces imparted by the ciliary muscles to themovement members 66, and thereafter to the optic 64. Such a force distribution system helps improve accommodation of theIOL 60. - The
optics IOL 10 to be rolled or folded for insertion through a small incision into the eye. Although the optic 12 as shown is a refractive lens body, the present IOLs may include a diffractive lens body, and such embodiment is included within the scope of the present invention. - The optic12 may be either integral with or mechanically coupled to the
member 16. Themember 16 may be constructed of the same or different biocompatible materials as the optic 12, and is preferably made of polymeric materials such as polypropylene, silicone polymeric materials, acrylic polymeric materials, and the like. Themovement assembly 14 is preferably deformable in much the same manner as the optic 12 to facilitate the passage of theIOL 10 through a small incision into the eye. The material or materials of construction from which themovement assembly 14 is made are chosen to provide the assembly with the desired mechanical properties, e.g., strength and deformability, to meet the needs of the particular application involved. - The
IOL 10 may be inserted into thecapsular bag 28 of a mammalian eye using conventional equipment and techniques, for example, after the natural crystalline lens is removed using a phaceomulsification technique. TheIOL 10 is preferably rolled or folded prior to insertion into the eye so as to fit through a small incision, for example, on the order of about 3.2 mm. After insertion, theIOL 10 may be positioned in the eye as shown in FIG. 2. - If the
IOL 10 is to be implanted in an adult human eye, the optic 12 preferably has a diameter in the range of about 3.5 mm to about 7 mm and, more preferably, in the range of about 5 mm to about 6 mm. Further, theIOL 10 may have an overall diameter, with themovement assembly 14 in an unstressed condition, of about 8 mm to about 11 mm or 12 mm. Additionally, the optic 12 preferably has a far-vision correction power for infinity in an accommodated state. - The present invention provides accommodating IOLs and methods for using such IOLs. The IOLs of the invention are configured to reduce the stretching of the capsular bag, to maintain the elasticity and/or integrity of the capsular bag, to enhance the effectiveness of the eye, particularly the function of the ciliary muscle and the zonules. The present IOLs promote the secure retention within the capsular bag by providing an enlarged contact surface to which cells and fibrin may grow. In addition, the present IOLs inhibit PCO. These benefits are obtained with IOLs which are streamlined in construction and relatively easy to manufacture and insert into the eye and which effectively provide accommodation for long-term use.
- While the present invention has been described with respect to various specific examples and embodiments, it is to be understood that the invention is not limited thereto and that it can be variously practiced within the scope of the following claims.
Claims (34)
1. An intraocular lens comprising:
an optic adapted to focus light to a retina of an eye and having a central optical axis; and
a movement assembly coupled to the optic and adapted to cooperate with the eye to effect accommodating movement of the optic;
the movement assembly including a movement member having a proximal region coupled to the optic, the movement member extending radially outwardly from the optic and including an enlarged distal region having a contact surface adapted to be in contact with a peripheral region of a capsular bag of an eye.
2. The intraocular lens of claim 1 wherein the movement assembly is positioned relative to the optic so that, with the intraocular lens at rest, the proximal region of the movement member is positioned at an angle other than 90° relative to the central optical axis of the optic.
3. The intraocular lens of claim 1 wherein the movement assembly is adapted and configured to fit within the capsular bag of a human eye.
4. The intraocular lens of claim 1 wherein the enlarged distal region is configured so that the contact surface is angled with respect to the proximal region.
5. The intraocular lens of claim 1 wherein the enlarged distal region is configured so that the contact surface is substantially coaxial with the optical axis of the optic.
6. The intraocular lens of claim 5 wherein the contact surface has an axial length of at least about 1 mm.
7. The intraocular lens of claim 5 wherein the contact surface is rounded in a radial plane through the optical axis.
8. The intraocular lens of claim 1 wherein the enlarged distal region includes a plurality of through holes extending through the contact surface.
9. The intraocular lens of claim 1 wherein the movement assembly includes a plurality of the movement members circumferentially spaced apart.
10. The intraocular lens of claim 9 wherein, with the intraocular lens at rest, the proximal region of each of the plurality of movement members is positioned at an angle other than 90° relative to the central axis of the optic.
11. The intraocular lens of claim 9 wherein each of the plurality of movement members includes a hinge disposed proximally of the enlarged distal region.
12. The intraocular lens of claim 9 wherein the movement assembly includes a plurality of spacer regions located between circumferentially adjacent movement members, the spacer regions being open or at least partially covered with a structural material having increased flexibility relative to the movement members.
13. The intraocular lens of claim 1 further comprising a second optic coupled to the movement assembly.
14. The intraocular lens of claim 1 further comprising a second optic separate from the optic, and at least one haptic member coupled to the second optic and the distal region of the movement member.
15. The intraocular lens of claim 14 wherein, with the intraocular lens at rest, the optic is anteriorly vaulted and the secondary optic is posteriorly vaulted.
16. The intraocular lens of claim 1 wherein the proximal region is joined to the distal region so that one or more sharp edges are present between the proximal region and the distal region.
17. An intraocular lens comprising:
an optic adapted to focus light to a retina of an eye and having a central optical axis; and
a movement assembly coupled to the optic and adapted to cooperate with the eye to effect accommodating movement of the optic;
the movement assembly including a plurality of movement members each having a proximal region coupled to the optic and an enlarged distal region; and
each of the enlarged distal regions having a contact surface adapted to be in contact with a peripheral region of a capsular bag of an eye.
18. The intraocular lens of claim 17 wherein the movement assembly is positioned relative to the optic so that, with the intraocular lens at rest, the optic is anteriorly vaulted.
19. The intraocular lens of claim 17 wherein the movement assembly is adapted to fit within the capsular bag of a human eye.
20. The intraocular lens of claim 17 wherein each of the enlarged distal regions is configured such that the contact surface is angled with respect to the proximal region.
21. The intraocular lens of claim 17 wherein each of the enlarged distal regions is configured such that the contact surface thereof is substantially parallel with the optical axis of the optic.
22. The intraocular lens of claim 17 wherein each of the enlarged distal regions is configured such that the contact surface thereof is substantially rounded.
23. The intraocular lens of claim 17 wherein each of the enlarged distal regions includes a plurality of through holes extending through the contact surface.
24. The intraocular lens of claim 17 which is deformable to be passed through a small incision for insertion into an eye.
25. The intraocular lens of claim 17 wherein each of the plurality of movement members includes a hinge disposed proximally of the enlarged distal region.
26. The intraocular lens of claim 17 further comprising a second optic coupled to the movement assembly.
27. The intraocular lens of claim 26 wherein said movement assembly includes a plurality of haptic members, each haptic member being coupled to the second optic and to one of the enlarged distal regions.
28. The intraocular lens of claim 27 , wherein the haptic members are positioned so that, with the intraocular lens at rest, the secondary optic is posteriorly vaulted.
29. The intraocular lens of claim 17 , wherein each of the proximal regions is joined to one of the distal regions so that one or more sharp edges are present therebetween.
30. The intraocular lens of claim 17 , and wherein the enlarged distal region of each movement member is formed separately from and mechanically coupled to the proximal region of that movement member.
31. The intraocular lens of claim 30 , wherein the optic and the proximal region of each movement member are integrally formed, and wherein the movement assembly includes a plurality of the movement members circumferentially spaced apart.
32. The intraocular lens of claim 31 , wherein each distal region comprises an arcuate segment having at least one groove for receiving and mechanically coupling to a proximal region of a movement member.
33. The intraocular lens of claim 32 , wherein each arcuate segment includes a pair of grooves each for receiving and mechanically coupling to a proximal region of a movement member, the intraocular lens being a two-optic lens.
34. The intraocular lens of claim 30 , wherein the enlarged distal region of each movement member is mechanically coupled to the proximal region of that movement member using adhesive.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US10/329,076 US20030109925A1 (en) | 2000-03-09 | 2002-12-23 | Accommodating intraocular lens |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US09/522,326 US6551354B1 (en) | 2000-03-09 | 2000-03-09 | Accommodating intraocular lens |
US10/329,076 US20030109925A1 (en) | 2000-03-09 | 2002-12-23 | Accommodating intraocular lens |
Related Parent Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US09/522,326 Continuation US6551354B1 (en) | 2000-03-09 | 2000-03-09 | Accommodating intraocular lens |
Publications (1)
Publication Number | Publication Date |
---|---|
US20030109925A1 true US20030109925A1 (en) | 2003-06-12 |
Family
ID=24080414
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US09/522,326 Expired - Lifetime US6551354B1 (en) | 2000-03-09 | 2000-03-09 | Accommodating intraocular lens |
US10/329,076 Abandoned US20030109925A1 (en) | 2000-03-09 | 2002-12-23 | Accommodating intraocular lens |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US09/522,326 Expired - Lifetime US6551354B1 (en) | 2000-03-09 | 2000-03-09 | Accommodating intraocular lens |
Country Status (9)
Country | Link |
---|---|
US (2) | US6551354B1 (en) |
EP (1) | EP1292247B1 (en) |
JP (1) | JP3958576B2 (en) |
AT (1) | ATE353198T1 (en) |
AU (1) | AU2001247288A1 (en) |
BR (1) | BR0109063A (en) |
CA (1) | CA2401972C (en) |
DE (1) | DE60126489T2 (en) |
WO (1) | WO2001066042A1 (en) |
Cited By (68)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20020116057A1 (en) * | 2001-01-25 | 2002-08-22 | Ting Albert C. | Optic configuration for intraocular lens system |
US20030078657A1 (en) * | 2001-01-25 | 2003-04-24 | Gholam-Reza Zadno-Azizi | Materials for use in accommodating intraocular lens system |
US20030109926A1 (en) * | 2001-12-10 | 2003-06-12 | Valdemar Portney | Accommodating intraocular lens |
US20040162612A1 (en) * | 2003-02-13 | 2004-08-19 | Valdemar Portney | Accommodating intraocular lens system with enhanced range of motion |
US20040190153A1 (en) * | 2002-12-12 | 2004-09-30 | Powervision | Lens system and method for power adjustment using externally actuated micropumps |
US20070010880A1 (en) * | 2002-12-12 | 2007-01-11 | Powervision, Inc. | Methods of adjusting the power of an intraocular lens |
US20070078515A1 (en) * | 2005-09-30 | 2007-04-05 | Brady Daniel G | Deformable intraocular lenses and lens systems |
US20070106377A1 (en) * | 2002-12-12 | 2007-05-10 | Powervision, Inc. | Accommodating intraocular lens system having spherical aberration compensation and method |
US20070191941A1 (en) * | 2004-06-03 | 2007-08-16 | Burkhard Dick | Capsular equatorial ring |
US20070213817A1 (en) * | 2002-12-12 | 2007-09-13 | Victor Esch | Accommodating intraocular lens having peripherally actuated deflectable surface and method |
US20070244560A1 (en) * | 2006-04-12 | 2007-10-18 | Alexei Ossipov | Intraocular lens with distortion free valve |
US20070260308A1 (en) * | 2006-05-02 | 2007-11-08 | Alcon, Inc. | Accommodative intraocular lens system |
US20080015689A1 (en) * | 2002-12-12 | 2008-01-17 | Victor Esch | Accommodating Intraocular Lens System and Method |
US20080046075A1 (en) * | 2002-12-12 | 2008-02-21 | Esch Victor C | Accommodating Intraocular Lens System and Method |
US20080125790A1 (en) * | 2006-11-29 | 2008-05-29 | George Tsai | Apparatus and methods for compacting an intraocular lens |
US20090018652A1 (en) * | 2006-12-22 | 2009-01-15 | Amo Groningen Bv | Accommodating intraocular lenses and associated systems, frames, and methods |
US7776088B2 (en) | 2001-08-31 | 2010-08-17 | Powervision, Inc. | Intraocular lens system and method for power adjustment |
US20110071628A1 (en) * | 2009-09-24 | 2011-03-24 | Rainbow Medical Ltd. | Accommodative intraocular lens |
US8048155B2 (en) | 2002-02-02 | 2011-11-01 | Powervision, Inc. | Intraocular implant devices |
US8158712B2 (en) | 2007-02-21 | 2012-04-17 | Powervision, Inc. | Polymeric materials suitable for ophthalmic devices and methods of manufacture |
CN102727325A (en) * | 2007-05-29 | 2012-10-17 | S·J.·戴尔 | Accommodative intraocular lens having a haptic plate |
US8303656B2 (en) | 2003-03-06 | 2012-11-06 | Powervision, Inc. | Adaptive optic lens and method of making |
US8314927B2 (en) | 2007-07-23 | 2012-11-20 | Powervision, Inc. | Systems and methods for testing intraocular lenses |
US20120310341A1 (en) * | 2009-11-17 | 2012-12-06 | Akkolens International B.V. | Accommodative Intraocular Lens Driven by Ciliary Mass |
US8328869B2 (en) | 2002-12-12 | 2012-12-11 | Powervision, Inc. | Accommodating intraocular lenses and methods of use |
US8343216B2 (en) | 2002-01-14 | 2013-01-01 | Abbott Medical Optics Inc. | Accommodating intraocular lens with outer support structure |
US8361145B2 (en) | 2002-12-12 | 2013-01-29 | Powervision, Inc. | Accommodating intraocular lens system having circumferential haptic support and method |
US8377123B2 (en) | 2004-11-10 | 2013-02-19 | Visiogen, Inc. | Method of implanting an intraocular lens |
US8425597B2 (en) | 1999-04-30 | 2013-04-23 | Abbott Medical Optics Inc. | Accommodating intraocular lenses |
US8447086B2 (en) | 2009-08-31 | 2013-05-21 | Powervision, Inc. | Lens capsule size estimation |
US8668734B2 (en) | 2010-07-09 | 2014-03-11 | Powervision, Inc. | Intraocular lens delivery devices and methods of use |
US8734512B2 (en) | 2011-05-17 | 2014-05-27 | James Stuart Cumming | Biased accommodating intraocular lens |
US8764823B2 (en) | 2010-06-21 | 2014-07-01 | James Stuart Cumming | Semi-rigid framework for a plate haptic accommodating intraocular lens |
US8900298B2 (en) | 2010-02-23 | 2014-12-02 | Powervision, Inc. | Fluid for accommodating intraocular lenses |
US8956408B2 (en) | 2007-07-23 | 2015-02-17 | Powervision, Inc. | Lens delivery system |
US8968396B2 (en) | 2007-07-23 | 2015-03-03 | Powervision, Inc. | Intraocular lens delivery systems and methods of use |
US9011532B2 (en) | 2009-06-26 | 2015-04-21 | Abbott Medical Optics Inc. | Accommodating intraocular lenses |
US9034036B2 (en) | 2010-06-21 | 2015-05-19 | James Stuart Cumming | Seamless-vision, tilted intraocular lens |
US9039760B2 (en) | 2006-12-29 | 2015-05-26 | Abbott Medical Optics Inc. | Pre-stressed haptic for accommodating intraocular lens |
US9198752B2 (en) | 2003-12-15 | 2015-12-01 | Abbott Medical Optics Inc. | Intraocular lens implant having posterior bendable optic |
US9271830B2 (en) | 2002-12-05 | 2016-03-01 | Abbott Medical Optics Inc. | Accommodating intraocular lens and method of manufacture thereof |
US9295545B2 (en) | 2012-06-05 | 2016-03-29 | James Stuart Cumming | Intraocular lens |
US9295546B2 (en) | 2013-09-24 | 2016-03-29 | James Stuart Cumming | Anterior capsule deflector ridge |
US9295544B2 (en) | 2012-06-05 | 2016-03-29 | James Stuart Cumming | Intraocular lens |
US9351825B2 (en) | 2013-12-30 | 2016-05-31 | James Stuart Cumming | Semi-flexible posteriorly vaulted acrylic intraocular lens for the treatment of presbyopia |
US9585745B2 (en) | 2010-06-21 | 2017-03-07 | James Stuart Cumming | Foldable intraocular lens with rigid haptics |
US9603703B2 (en) | 2009-08-03 | 2017-03-28 | Abbott Medical Optics Inc. | Intraocular lens and methods for providing accommodative vision |
US9610155B2 (en) | 2008-07-23 | 2017-04-04 | Powervision, Inc. | Intraocular lens loading systems and methods of use |
US9615916B2 (en) | 2013-12-30 | 2017-04-11 | James Stuart Cumming | Intraocular lens |
US9814570B2 (en) | 1999-04-30 | 2017-11-14 | Abbott Medical Optics Inc. | Ophthalmic lens combinations |
US9872763B2 (en) | 2004-10-22 | 2018-01-23 | Powervision, Inc. | Accommodating intraocular lenses |
US9918830B2 (en) | 2010-06-21 | 2018-03-20 | James Stuart Cumming | Foldable intraocular lens with rigid haptics |
US9925039B2 (en) | 2012-12-26 | 2018-03-27 | Rainbow Medical Ltd. | Accommodative intraocular lens |
US9968441B2 (en) | 2008-03-28 | 2018-05-15 | Johnson & Johnson Surgical Vision, Inc. | Intraocular lens having a haptic that includes a cap |
US9987125B2 (en) | 2012-05-02 | 2018-06-05 | Johnson & Johnson Surgical Vision, Inc. | Intraocular lens with shape changing capability to provide enhanced accomodation and visual acuity |
US10045844B2 (en) | 2002-02-02 | 2018-08-14 | Powervision, Inc. | Post-implant accommodating lens modification |
US10195020B2 (en) | 2013-03-15 | 2019-02-05 | Powervision, Inc. | Intraocular lens storage and loading devices and methods of use |
US10258462B2 (en) | 2012-12-26 | 2019-04-16 | Rainbow Medical Ltd. | Accommodative intraocular lens |
US10299913B2 (en) | 2009-01-09 | 2019-05-28 | Powervision, Inc. | Accommodating intraocular lenses and methods of use |
US10327886B2 (en) | 2016-06-01 | 2019-06-25 | Rainbow Medical Ltd. | Accomodative intraocular lens |
US10390937B2 (en) | 2007-07-23 | 2019-08-27 | Powervision, Inc. | Accommodating intraocular lenses |
US10433949B2 (en) | 2011-11-08 | 2019-10-08 | Powervision, Inc. | Accommodating intraocular lenses |
US10441411B2 (en) | 2016-12-29 | 2019-10-15 | Rainbow Medical Ltd. | Accommodative intraocular lens |
US10835373B2 (en) | 2002-12-12 | 2020-11-17 | Alcon Inc. | Accommodating intraocular lenses and methods of use |
US11426270B2 (en) | 2015-11-06 | 2022-08-30 | Alcon Inc. | Accommodating intraocular lenses and methods of manufacturing |
US11471272B2 (en) | 2019-10-04 | 2022-10-18 | Alcon Inc. | Adjustable intraocular lenses and methods of post-operatively adjusting intraocular lenses |
US11707354B2 (en) | 2017-09-11 | 2023-07-25 | Amo Groningen B.V. | Methods and apparatuses to increase intraocular lenses positional stability |
US12059342B2 (en) | 2015-06-10 | 2024-08-13 | Alcon Inc. | Intraocular lens materials and components |
Families Citing this family (102)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20040015236A1 (en) * | 1991-11-18 | 2004-01-22 | Sarfarazi Faezeh M. | Sarfarazi elliptical accommodative intraocular lens for small incision surgery |
ES2227581T3 (en) * | 1995-02-15 | 2005-04-01 | Medevec Licensing B.V. | INTRAOCULAR ACCOMMODATION LENS THAT HAS HAPPY IN THE FORM OF T. |
US20060149369A1 (en) * | 1997-05-20 | 2006-07-06 | C&C Vision International Limited | Accommodating arching lens |
US8556967B2 (en) | 1999-04-09 | 2013-10-15 | Faezeh Mona Sarfarazi | Interior bag for a capsular bag and injector |
US7662179B2 (en) | 1999-04-09 | 2010-02-16 | Sarfarazi Faezeh M | Haptics for accommodative intraocular lens system |
WO2002019949A2 (en) * | 2000-09-07 | 2002-03-14 | Allergan Sales, Inc. | Intraocular lens with a posterior lens portion |
US20030078658A1 (en) * | 2001-01-25 | 2003-04-24 | Gholam-Reza Zadno-Azizi | Single-piece accomodating intraocular lens system |
US7198640B2 (en) * | 2001-01-25 | 2007-04-03 | Visiogen, Inc. | Accommodating intraocular lens system with separation member |
US8062361B2 (en) * | 2001-01-25 | 2011-11-22 | Visiogen, Inc. | Accommodating intraocular lens system with aberration-enhanced performance |
US6818158B2 (en) * | 2001-01-25 | 2004-11-16 | Visiogen, Inc. | Accommodating intraocular lens system and method of making same |
US6884261B2 (en) * | 2001-01-25 | 2005-04-26 | Visiogen, Inc. | Method of preparing an intraocular lens for implantation |
US7780729B2 (en) * | 2004-04-16 | 2010-08-24 | Visiogen, Inc. | Intraocular lens |
US20120016349A1 (en) | 2001-01-29 | 2012-01-19 | Amo Development, Llc. | Hybrid ophthalmic interface apparatus and method of interfacing a surgical laser with an eye |
US6524340B2 (en) * | 2001-05-23 | 2003-02-25 | Henry M. Israel | Accommodating intraocular lens assembly |
DE10139027A1 (en) * | 2001-08-15 | 2003-02-27 | Humanoptics Ag | Intraocular implant |
US6443985B1 (en) * | 2001-08-27 | 2002-09-03 | Randall Woods | Intraocular lens implant having eye accommodating capabilities |
AU2003210534A1 (en) * | 2002-01-14 | 2003-07-30 | Advanced Medical Optics, Inc. | Accommodating intraocular lens with integral capsular bag ring |
US20050021139A1 (en) * | 2003-02-03 | 2005-01-27 | Shadduck John H. | Ophthalmic devices, methods of use and methods of fabrication |
US6695881B2 (en) | 2002-04-29 | 2004-02-24 | Alcon, Inc. | Accommodative intraocular lens |
US20040034417A1 (en) * | 2002-08-16 | 2004-02-19 | Heyman Thomas M. | Intraocular lens |
US20040243232A1 (en) * | 2002-09-13 | 2004-12-02 | Eyeonics, Inc | Lens for increased depth of focus |
US7125422B2 (en) * | 2002-10-25 | 2006-10-24 | Quest Vision Technology, Inc. | Accommodating intraocular lens implant |
US20040082993A1 (en) | 2002-10-25 | 2004-04-29 | Randall Woods | Capsular intraocular lens implant having a refractive liquid therein |
US20040082995A1 (en) * | 2002-10-25 | 2004-04-29 | Randall Woods | Telescopic intraocular lens implant for treating age-related macular degeneration |
US7615056B2 (en) * | 2003-02-14 | 2009-11-10 | Visiogen, Inc. | Method and device for compacting an intraocular lens |
US20040249455A1 (en) * | 2003-06-09 | 2004-12-09 | Tran Son Trung | Accommodative intraocular lens system |
US20050027354A1 (en) * | 2003-07-28 | 2005-02-03 | Advanced Medical Optics, Inc. | Primary and supplemental intraocular lens |
US20050125058A1 (en) * | 2003-12-03 | 2005-06-09 | Eyeonics, Inc. | Accommodating hybrid intraocular lens |
US7553327B2 (en) | 2003-12-04 | 2009-06-30 | The Nice Trust, A Trust Of The Isle Of Man | Accommodating 360 degree sharp edge optic plate haptic lens |
US7645300B2 (en) | 2004-02-02 | 2010-01-12 | Visiogen, Inc. | Injector for intraocular lens system |
US7806929B2 (en) * | 2004-08-27 | 2010-10-05 | Brown David C | Intracapsular pseudophakic device |
US20060241752A1 (en) * | 2005-04-20 | 2006-10-26 | Israel Henry M | Accommodating multiple lens assembly |
US7771471B2 (en) | 2005-05-13 | 2010-08-10 | C & C Vision International Limited | Floating optic accommodating intraocular lens |
US7591849B2 (en) | 2005-07-01 | 2009-09-22 | Bausch & Lomb Incorpoted | Multi-component accommodative intraocular lens with compressible haptic |
US20070016293A1 (en) * | 2005-07-18 | 2007-01-18 | Alcon, Inc. | Accommodative intraocular lens system |
US20070032866A1 (en) * | 2005-08-05 | 2007-02-08 | Valdemar Portney | Accommodating diffractive intraocular lens |
US20070032868A1 (en) * | 2005-08-08 | 2007-02-08 | Randall Woods | Capsular shape-restoring device |
US20070088433A1 (en) * | 2005-10-17 | 2007-04-19 | Powervision | Accommodating intraocular lens system utilizing direct force transfer from zonules and method of use |
US20080294254A1 (en) * | 2005-12-06 | 2008-11-27 | Cumming J Stuart | Intraocular lens |
US20070129803A1 (en) * | 2005-12-06 | 2007-06-07 | C&C Vision International Limited | Accommodative Intraocular Lens |
US7985253B2 (en) * | 2005-12-07 | 2011-07-26 | C&C Vision International Limited | Hydrolic accommodating intraocular lens |
US7981155B2 (en) * | 2005-12-07 | 2011-07-19 | C&C Vision International Limited | Hydrolic accommodating intraocular lens |
US20070129800A1 (en) * | 2005-12-07 | 2007-06-07 | C&C Vision International Limited | Hydrolic accommodating intraocular lens |
US20070168027A1 (en) * | 2006-01-13 | 2007-07-19 | Brady Daniel G | Accommodating diffractive intraocular lens |
US7837730B2 (en) * | 2006-02-21 | 2010-11-23 | C & C International Limited | Floating optic accommodating intraocular lens |
US20070260309A1 (en) * | 2006-05-08 | 2007-11-08 | Richardson Gary A | Accommodating intraocular lens having a recessed anterior optic |
WO2007134019A2 (en) * | 2006-05-08 | 2007-11-22 | Bausch & Lomb Incorporated | Accommodative intraocular lens having defined axial compression characteristics |
US20080021549A1 (en) * | 2006-07-21 | 2008-01-24 | Eagan Barry T | Accommodating intraocular lens having an active power source |
US7763070B2 (en) * | 2006-07-25 | 2010-07-27 | C&C Vision International Limited | “W” accommodating intraocular lens |
US20080027539A1 (en) * | 2006-07-25 | 2008-01-31 | Cumming J Stuart | "W" Accommodating Intraocular Lens |
US8163015B2 (en) | 2006-07-25 | 2012-04-24 | C&C Vision International Limited | “W” accommodating intraocular lens |
US20080027538A1 (en) * | 2006-07-27 | 2008-01-31 | Cumming J Stuart | Polyspheric Accommodating Intraocular Lens |
US20080027540A1 (en) * | 2006-07-31 | 2008-01-31 | Cumming J Stuart | Stabilized accommodating intraocular lens |
US20080046077A1 (en) * | 2006-08-15 | 2008-02-21 | C&C Vision International Limited | Multiocular Intraocular Lens Systems |
WO2008079671A1 (en) * | 2006-12-22 | 2008-07-03 | Bausch & Lomb Incorporated | Multi-element accommodative intraocular lens |
CA2674018C (en) | 2006-12-29 | 2015-05-26 | Advanced Medical Optics, Inc. | Multifocal accommodating intraocular lens |
US7713299B2 (en) | 2006-12-29 | 2010-05-11 | Abbott Medical Optics Inc. | Haptic for accommodating intraocular lens |
US8066769B2 (en) * | 2007-01-29 | 2011-11-29 | Werblin Research & Development Corp. | Intraocular lens system |
US9398949B2 (en) * | 2007-01-29 | 2016-07-26 | Emmetropia, Inc. | Intraocular lens system |
US8066768B2 (en) * | 2007-01-29 | 2011-11-29 | Werblin Research & Development Corp. | Intraocular lens system |
US7811320B2 (en) * | 2007-01-29 | 2010-10-12 | Werblin Research & Development Corp. | Intraocular lens system |
US8034106B2 (en) * | 2007-02-02 | 2011-10-11 | Adoptics Ag | Interfacial refraction accommodating lens (IRAL) |
WO2008097915A1 (en) * | 2007-02-02 | 2008-08-14 | Key Medical Technologies, Inc. | Interfacial refraction accommodating lens (iral) |
US20080306587A1 (en) * | 2007-02-21 | 2008-12-11 | Jingjong Your | Lens Material and Methods of Curing with UV Light |
US20090005866A1 (en) * | 2007-03-13 | 2009-01-01 | C&C Vision International Limited | First elastic hinge accommodating intraocular lens |
US20080281415A1 (en) * | 2007-03-13 | 2008-11-13 | C&C Vision International Limited | Second elastic hinge accommodating intraocular lens |
US20080288066A1 (en) * | 2007-05-16 | 2008-11-20 | C&C Vision International Limited | Toric sulcus lens |
US20090228101A1 (en) * | 2007-07-05 | 2009-09-10 | Visiogen, Inc. | Intraocular lens with post-implantation adjustment capabilities |
US8414646B2 (en) | 2007-12-27 | 2013-04-09 | Forsight Labs, Llc | Intraocular, accommodating lens and methods of use |
EP3381407A1 (en) | 2008-01-03 | 2018-10-03 | Forsight Labs, Llc | Intraocular, accomodating lens and methods of use |
US8425595B2 (en) | 2008-03-12 | 2013-04-23 | Visiogen, Inc. | Method for inserting an intraocular lens |
US9943402B2 (en) | 2008-11-20 | 2018-04-17 | Insight Innovations, Llc | Micropatterned intraocular implant |
ES2606491T3 (en) | 2008-11-20 | 2017-03-24 | Insight Innovations, Llc | Biodegradable and biocompatible intraocular implant system |
US20120232649A1 (en) | 2008-11-20 | 2012-09-13 | Insight Innovations, Llc | Intraocular Lens Cell Migration Inhibition System |
US9039762B2 (en) * | 2010-03-23 | 2015-05-26 | Novartis Ag | Accommodating intraocular lens using trapezoidal phase shift |
CN102883682A (en) | 2010-04-27 | 2013-01-16 | 雷恩斯根公司 | Accommodating intraocular lens device |
EP2806828B1 (en) | 2012-01-24 | 2021-07-21 | The Regents of The University of Colorado, A Body Corporate | Modular intraocular lens designs and methods |
US10028824B2 (en) | 2012-01-24 | 2018-07-24 | Clarvista Medical, Inc. | Modular intraocular lens designs, tools and methods |
US9364316B1 (en) | 2012-01-24 | 2016-06-14 | Clarvista Medical, Inc. | Modular intraocular lens designs, tools and methods |
US10080648B2 (en) | 2012-01-24 | 2018-09-25 | Clarvista Medical, Inc. | Modular intraocular lens designs, tools and methods |
EP2838472B1 (en) | 2012-04-20 | 2020-09-23 | Hanita Lenses R.C.A. Ltd. | Intraocular assembly |
JP5436618B2 (en) * | 2012-06-05 | 2014-03-05 | 株式会社中京メディカル | Intraocular lens |
DE102012016893A1 (en) | 2012-08-24 | 2014-05-15 | Be Innovative Gmbh | Intraocular lens, in particular capsular bag intraocular lens |
WO2015066532A1 (en) | 2013-11-01 | 2015-05-07 | Daniel Brady | Two-part accommodating intraocular lens device |
JP6625975B2 (en) | 2013-11-01 | 2019-12-25 | レンスゲン、インコーポレイテッド | Accommodating intraocular lens device |
JP2017505702A (en) | 2014-02-18 | 2017-02-23 | クラービスタ メディカル, インコーポレイテッドClarvista Medical, Inc. | Modular intraocular lens design, apparatus and method |
CA2942202C (en) | 2014-03-10 | 2023-01-31 | Amo Groningen B.V. | Dual-optic intraocular lens that improves overall vision where there is a local loss of retinal function |
US10010407B2 (en) | 2014-04-21 | 2018-07-03 | Amo Groningen B.V. | Ophthalmic devices that improve peripheral vision |
US10004596B2 (en) | 2014-07-31 | 2018-06-26 | Lensgen, Inc. | Accommodating intraocular lens device |
EP3197462A4 (en) | 2014-09-23 | 2018-05-30 | Lensgen, Inc | Polymeric material for accommodating intraocular lenses |
EP3250152A1 (en) | 2015-01-30 | 2017-12-06 | Clarvista Medical, Inc. | Modular intraocular lens designs |
CN108348327B (en) | 2015-11-04 | 2021-10-01 | 克拉维斯塔医疗有限公司 | Modular intraocular lens design, tools and methods |
EP3383320A4 (en) | 2015-12-01 | 2019-08-21 | Lensgen, Inc | Accommodating intraocular lens device |
US10588738B2 (en) | 2016-03-11 | 2020-03-17 | Amo Groningen B.V. | Intraocular lenses that improve peripheral vision |
EP3445288B1 (en) * | 2016-04-19 | 2020-11-04 | AMO Groningen B.V. | Ophthalmic devices, system and methods that improve peripheral vision |
US11045309B2 (en) | 2016-05-05 | 2021-06-29 | The Regents Of The University Of Colorado | Intraocular lens designs for improved stability |
EP3463188B1 (en) | 2016-05-27 | 2023-04-26 | LensGen, Inc. | Lens oil having a narrow molecular weight distribution for intraocular lens devices |
US11382736B2 (en) | 2017-06-27 | 2022-07-12 | Alcon Inc. | Injector, intraocular lens system, and related methods |
US10898316B2 (en) | 2018-03-01 | 2021-01-26 | Jellisee Ophthalmics Inc | Intraocular lens |
EP3962412A1 (en) | 2019-05-03 | 2022-03-09 | Jellisee Ophthalmics Inc. | Intraocular lenses with shape-changing optics |
US11759309B2 (en) | 2020-04-29 | 2023-09-19 | Long Bridge Medical, Inc. | Devices to support and position an intraocular lens within the eye and methods of use |
US11357620B1 (en) | 2021-09-10 | 2022-06-14 | California LASIK & Eye, Inc. | Exchangeable optics and therapeutics |
Citations (98)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US1483509A (en) * | 1921-05-05 | 1924-02-12 | Franklin Optical Company | Process of making fused bifocal lenses |
US2129305A (en) * | 1936-08-21 | 1938-09-06 | Feinbloom William | Contact lens |
US2274142A (en) * | 1940-01-15 | 1942-02-24 | Revalens Co | Multifocal ophthalmic lens |
US2405989A (en) * | 1941-08-12 | 1946-08-20 | Beach Lens Corp | Lens |
US2511517A (en) * | 1947-01-31 | 1950-06-13 | Bell & Howell Co | Method of producing optical glass of varied refractive index |
US3031927A (en) * | 1958-03-03 | 1962-05-01 | Plastic Contact Lens Company | Bifocal corneal contact lens |
US3034403A (en) * | 1959-04-03 | 1962-05-15 | Neefe Hamilton Res Company | Contact lens of apparent variable light absorption |
US3227507A (en) * | 1961-08-16 | 1966-01-04 | Feinbloom William | Corneal contact lens having inner ellipsoidal surface |
US3339997A (en) * | 1962-07-30 | 1967-09-05 | Plastic Contact Lens Company | Bifocal ophthalmic lens having different color distance and near vision zones |
US3420006A (en) * | 1964-01-27 | 1969-01-07 | Howard J Barnett | Apparatus for grinding multifocal lens |
US3431327A (en) * | 1964-08-31 | 1969-03-04 | George F Tsuetaki | Method of making a bifocal contact lens with an embedded metal weight |
US3693301A (en) * | 1970-05-27 | 1972-09-26 | Anvar | Method for producing optical elements with aspherical surfaces |
US3932148A (en) * | 1975-01-21 | 1976-01-13 | Criterion Manufacturing Company, Inc. | Method and apparatus for making complex aspheric optical surfaces |
US4162122A (en) * | 1977-09-14 | 1979-07-24 | Cohen Allen L | Zonal bifocal contact lens |
US4195919A (en) * | 1977-10-31 | 1980-04-01 | Shelton William A | Contact lens with reduced spherical aberration for aphakic eyes |
US4199231A (en) * | 1978-08-21 | 1980-04-22 | Evans Carl H | Hydrogel contact lens |
US4210391A (en) * | 1977-09-14 | 1980-07-01 | Cohen Allen L | Multifocal zone plate |
US4253199A (en) * | 1978-09-25 | 1981-03-03 | Surgical Design Corporation | Surgical method and apparatus for implants for the eye |
US4254509A (en) * | 1979-04-09 | 1981-03-10 | Tennant Jerald L | Accommodating intraocular implant |
US4274717A (en) * | 1979-05-18 | 1981-06-23 | Younger Manufacturing Company | Ophthalmic progressive power lens and method of making same |
US4315673A (en) * | 1978-04-06 | 1982-02-16 | Optische Werke G. Rodenstock | Progressive power ophthalmic lens |
US4316293A (en) * | 1979-08-27 | 1982-02-23 | Bayers Jon Herbert | Flexible intraocular lens |
US4338005A (en) * | 1978-12-18 | 1982-07-06 | Cohen Allen L | Multifocal phase place |
US4340283A (en) * | 1978-12-18 | 1982-07-20 | Cohen Allen L | Phase shift multifocal zone plate |
US4370760A (en) * | 1981-03-25 | 1983-02-01 | Kelman Charles D | Anterior chamber intraocular lens |
US4377329A (en) * | 1980-02-26 | 1983-03-22 | Stanley Poler | Contact lens or the like |
US4402579A (en) * | 1981-07-29 | 1983-09-06 | Lynell Medical Technology Inc. | Contact-lens construction |
US4404694A (en) * | 1982-03-18 | 1983-09-20 | Kelman Charles D | Intraocular lens |
US4504982A (en) * | 1982-08-05 | 1985-03-19 | Optical Radiation Corporation | Aspheric intraocular lens |
US4573775A (en) * | 1982-08-19 | 1986-03-04 | Vistakon, Inc. | Bifocal contact lens |
US4580882A (en) * | 1983-04-21 | 1986-04-08 | Benjamin Nuchman | Continuously variable contact lens |
US4596578A (en) * | 1984-01-30 | 1986-06-24 | Kelman Charles D | Intraocular lens with miniature optic |
US4636211A (en) * | 1984-03-13 | 1987-01-13 | Nielsen J Mchenry | Bifocal intra-ocular lens |
US4636049A (en) * | 1983-09-20 | 1987-01-13 | University Optical Products Co. | Concentric bifocal contact lens |
US4637697A (en) * | 1982-10-27 | 1987-01-20 | Pilkington P.E. Limited | Multifocal contact lenses utilizing diffraction and refraction |
US4641934A (en) * | 1982-09-29 | 1987-02-10 | Pilkington P.E. Limited | Ophthalmic lens with diffractive power |
US4676792A (en) * | 1986-08-26 | 1987-06-30 | Donald Praeger | Method and artificial intraocular lens device for the phakic treatment of myopia |
US4687484A (en) * | 1983-12-12 | 1987-08-18 | Kaplan Linda J | Anterior chamber intraocular lens |
US4693572A (en) * | 1985-06-03 | 1987-09-15 | Fused Kontacts Of Chicago, Inc. | Monocentric bifocal corneal contact lens |
US4720286A (en) * | 1984-07-20 | 1988-01-19 | Bailey Kelvin E | Multifocus intraocular lens |
US4752123A (en) * | 1985-11-19 | 1988-06-21 | University Optical Products Co. | Concentric bifocal contact lens with two distance power regions |
US4759762A (en) * | 1985-03-08 | 1988-07-26 | Grendahl Dennis T | Accommodating lens |
US4769033A (en) * | 1987-07-02 | 1988-09-06 | Nordan Lee T | Intraocular multifocal lens |
US4813955A (en) * | 1983-09-07 | 1989-03-21 | Manfred Achatz | Multifocal, especially bifocal, intraocular, artificial ophthalmic lens |
US4830481A (en) * | 1988-08-12 | 1989-05-16 | Minnesota Mining And Manufacturing Company | Multifocal diffractive lens |
US4842601A (en) * | 1987-05-18 | 1989-06-27 | Smith S Gregory | Accommodating intraocular lens and method of implanting and using same |
US4890913A (en) * | 1982-10-13 | 1990-01-02 | Carle John T De | Zoned multi-focal contact lens |
US4890912A (en) * | 1986-01-24 | 1990-01-02 | Rients Visser | Trifocal eye-contact lens |
US4892543A (en) * | 1989-02-02 | 1990-01-09 | Turley Dana F | Intraocular lens providing accomodation |
US4898461A (en) * | 1987-06-01 | 1990-02-06 | Valdemar Portney | Multifocal ophthalmic lens |
US4906246A (en) * | 1987-08-24 | 1990-03-06 | Grendahl Dennis T | Cylindrically segmented zone of focus artificial hydrogel lens |
US4917681A (en) * | 1987-08-24 | 1990-04-17 | Nordan Lee T | Intraocular multifocal lens |
US4919663A (en) * | 1987-08-24 | 1990-04-24 | Grendahl Dennis T | Laminated zone of focus artificial hydrogel lens |
US4921496A (en) * | 1987-08-24 | 1990-05-01 | Grendahl Dennis T | Radially segemented zone of focus artificial hydrogel lens |
US4923296A (en) * | 1988-07-14 | 1990-05-08 | Erickson Paul M | Oriented simultaneous vision bifocal contact lenses or the like utilizing introaocular suppression of blur |
US4932968A (en) * | 1987-07-07 | 1990-06-12 | Caldwell Delmar R | Intraocular prostheses |
US4932966A (en) * | 1988-08-15 | 1990-06-12 | Storz Instrument Company | Accommodating intraocular lens |
US4938583A (en) * | 1986-06-02 | 1990-07-03 | Miller Gregory N | Contact lens and method of making same |
US4955902A (en) * | 1989-11-13 | 1990-09-11 | Kelman Charles D | Decentered intraocular lens |
US4990159A (en) * | 1988-12-02 | 1991-02-05 | Kraff Manus C | Intraocular lens apparatus with haptics of varying cross-sectional areas |
US4994082A (en) * | 1988-09-09 | 1991-02-19 | Ophthalmic Ventures Limited Partnership | Accommodating intraocular lens |
US5000559A (en) * | 1988-02-29 | 1991-03-19 | Nikon Corporation | Ophthalmic lenses having progressively variable refracting power |
US5002382A (en) * | 1989-12-07 | 1991-03-26 | Leonard Seidner | Multifocal corneal contact lenses |
US5019098A (en) * | 1989-05-19 | 1991-05-28 | Essilor International Cie Generale D'optique | Sight-correcting optical component such as an intra-ocular implant or contact lens |
US5019099A (en) * | 1987-07-02 | 1991-05-28 | Nordan Lee T | Intraocular multifocal lens method for correcting the aphakic eye |
US5026396A (en) * | 1990-05-07 | 1991-06-25 | Darin John J | Two-piece intraocular lens |
US5047052A (en) * | 1987-11-06 | 1991-09-10 | Seymour Dubroff | Anterior chamber intraocular lens with four point fixation |
US5089024A (en) * | 1988-04-19 | 1992-02-18 | Storz Instrument Company | Multi-focal intraocular lens |
US5096285A (en) * | 1990-05-14 | 1992-03-17 | Iolab Corporation | Multifocal multizone diffractive ophthalmic lenses |
US5112351A (en) * | 1990-10-12 | 1992-05-12 | Ioptex Research Inc. | Multifocal intraocular lenses |
US5192318A (en) * | 1986-06-05 | 1993-03-09 | Schneider Richard T | One-piece bifocal intraocular lens construction |
US5192317A (en) * | 1988-07-26 | 1993-03-09 | Irvin Kalb | Multi focal intra-ocular lens |
US5201762A (en) * | 1987-05-20 | 1993-04-13 | Hauber Frederick A | Intraocular archromatic lens |
US5225858A (en) * | 1987-06-01 | 1993-07-06 | Valdemar Portney | Multifocal ophthalmic lens |
US5275623A (en) * | 1991-11-18 | 1994-01-04 | Faezeh Sarfarazi | Elliptical accommodative intraocular lens for small incision surgery |
US5443506A (en) * | 1992-11-18 | 1995-08-22 | Garabet; Antoine L. | Lens with variable optical properties |
US5480428A (en) * | 1993-04-22 | 1996-01-02 | Mezhotraslevoi Nauchno-Tekhnichesky Komplex "Mikrokhirurgia Glaza" | Corrective intraocular lens |
US5489302A (en) * | 1994-05-24 | 1996-02-06 | Skottun; Bernt C. | Accommodating intraocular lens |
US5496366A (en) * | 1990-04-27 | 1996-03-05 | Cumming; J. Stuart | Accommodating intraocular lens |
US5521656A (en) * | 1987-06-01 | 1996-05-28 | Portney; Valdemar | Method of making an ophthalmic lens |
US5549760A (en) * | 1994-12-01 | 1996-08-27 | White Consolidated Industries, Inc. | Mounting device for dishwasher insulation |
US5607472A (en) * | 1995-05-09 | 1997-03-04 | Emory University | Intraocular lens for restoring accommodation and allows adjustment of optical power |
US5609630A (en) * | 1994-08-22 | 1997-03-11 | Philippe Crozafon | Intraocular implant |
US5628796A (en) * | 1994-07-04 | 1997-05-13 | Suzuki; Taketoshi | Intraocular lens |
US5628795A (en) * | 1995-03-15 | 1997-05-13 | Langerman David W | Spare parts for use in ophthalmic surgical procedures |
US5652014A (en) * | 1991-08-16 | 1997-07-29 | Galin; Miles A. | Medicament coated refractive anterior chamber ocular implant |
US5652638A (en) * | 1995-05-04 | 1997-07-29 | Johnson & Johnson Vision Products, Inc. | Concentric annular ring lens designs for astigmatism |
US5766244A (en) * | 1991-05-23 | 1998-06-16 | Binder; Helmut | Intraocular artificial lens and method for fabricating same |
US5769890A (en) * | 1997-01-16 | 1998-06-23 | Henry H. McDonald | Placement of second artificial lens in eye, to correct for optical defects of first artificial lens in eye |
US5776191A (en) * | 1982-02-05 | 1998-07-07 | Staar Surgical Company | Fixation system for intraocular lens structures |
US5876442A (en) * | 1998-01-15 | 1999-03-02 | Visioncare Ltd. | Intraocular lens implant with telescope support |
US6013101A (en) * | 1994-11-21 | 2000-01-11 | Acuity (Israel) Limited | Accommodating intraocular lens implant |
US6096078A (en) * | 1997-10-20 | 2000-08-01 | Surgical Concepts, Inc. | Accommodative lens implantation |
US6176878B1 (en) * | 1998-12-17 | 2001-01-23 | Allergan Sales, Inc. | Accommodating intraocular lens |
US6186148B1 (en) * | 1998-02-04 | 2001-02-13 | Kiyoshi Okada | Prevention of posterior capsular opacification |
US6217612B1 (en) * | 1999-09-10 | 2001-04-17 | Randall Woods | Intraocular lens implant having eye accommodating capabilities |
US6224628B1 (en) * | 1999-04-23 | 2001-05-01 | Thinoptx, Inc. | Haptics for an intraocular lens |
US6387126B1 (en) * | 1995-02-15 | 2002-05-14 | J. Stuart Cumming | Accommodating intraocular lens having T-shaped haptics |
Family Cites Families (62)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
USRE25286E (en) | 1962-11-13 | Bifocal corneal contact lens | ||
US3210894A (en) | 1962-08-13 | 1965-10-12 | Kollmorgen Corp | Method of producing aspheric surfaces on mirrors or lenses |
US3482906A (en) | 1965-10-04 | 1969-12-09 | David Volk | Aspheric corneal contact lens series |
US3542461A (en) | 1967-11-20 | 1970-11-24 | Du Pont | Contact lens having an index of refraction approximating that of human tears |
US4055378A (en) | 1971-12-31 | 1977-10-25 | Agfa-Gevaert Aktiengesellschaft | Silicone contact lens with hydrophilic surface treatment |
CA1012392A (en) | 1973-08-16 | 1977-06-21 | American Optical Corporation | Progressive power ophthalmic lens |
US3922728A (en) | 1974-08-15 | 1975-12-02 | Krasnov Mikhail M | Artificial crystalline lens |
DE2610203B2 (en) | 1976-03-11 | 1981-01-22 | Optische Werke G. Rodenstock, 8000 Muenchen | Progressive lens |
JPS5942286B2 (en) | 1979-08-24 | 1984-10-13 | セイコーエプソン株式会社 | eyeglass lenses |
US4418991A (en) | 1979-09-24 | 1983-12-06 | Breger Joseph L | Presbyopic contact lens |
US4307945A (en) | 1980-02-14 | 1981-12-29 | Itek Corporation | Progressively varying focal power opthalmic lens |
USRE32525F1 (en) | 1980-04-01 | 1989-05-09 | Universal intraocular lens and a method of measuring an eye chamber size | |
US4409691A (en) | 1981-11-02 | 1983-10-18 | Levy Chauncey F | Focussable intraocular lens |
US4702244A (en) | 1982-02-05 | 1987-10-27 | Staar Surgical Company | Surgical device for implantation of a deformable intraocular lens |
DE3222099C2 (en) | 1982-06-11 | 1984-06-20 | Titmus Eurocon Kontaktlinsen Gmbh & Co Kg, 8750 Aschaffenburg | Bifocal contact lens of the bivisual type |
AU566263B2 (en) | 1982-07-22 | 1987-10-15 | Mazzocco, T.R. | Fixation system for intraocular lens prosthesis |
US4888015A (en) | 1982-08-20 | 1989-12-19 | Domino Rudolph S | Method of replacing an eye lens |
US4476591A (en) | 1982-10-07 | 1984-10-16 | Arnott Eric J | Lens implants for insertion in the human eye |
GB2129155B (en) | 1982-10-13 | 1987-05-20 | Ng Trustees & Nominees Ltd | Bifocal contact lenses |
DE3246306A1 (en) | 1982-12-14 | 1984-06-14 | Titmus Eurocon Kontaktlinsen Gmbh & Co Kg, 8750 Aschaffenburg | Bifocal lens of bivisual type |
US4618229A (en) | 1983-07-22 | 1986-10-21 | Bausch & Lomb Incorporated | Bifocal contact lens |
US4551864A (en) | 1983-08-18 | 1985-11-12 | Iolab Corporation | Anterior chamber lens |
GB2146791B (en) | 1983-09-16 | 1987-01-28 | Suwa Seikosha Kk | Progressive multifocal ophthalmic lens |
US4560383A (en) | 1983-10-27 | 1985-12-24 | Leiske Larry G | Anterior chamber intraocular lens |
US4629460A (en) * | 1984-06-25 | 1986-12-16 | Dyer Robert L | Intraocular lens |
US4976732A (en) | 1984-09-12 | 1990-12-11 | International Financial Associates Holdings, Inc. | Optical lens for the human eye |
US4725278A (en) * | 1985-01-22 | 1988-02-16 | Shearing Steven P | Intraocular lens |
GB2192291B (en) | 1986-03-04 | 1990-08-22 | Gupta Anil K | Progressive power contact lens. |
US4725277A (en) | 1986-05-14 | 1988-02-16 | Precision-Cosmet Co., Inc. | Intraocular lens with tapered haptics |
US4790847A (en) | 1987-05-26 | 1988-12-13 | Woods Randall L | Intraocular lens implant having eye focusing capabilities |
US5166712A (en) | 1987-06-01 | 1992-11-24 | Valdemar Portney | Multifocal ophthalmic lens |
US5166711A (en) | 1987-06-01 | 1992-11-24 | Valdemar Portney | Multifocal ophthalmic lens |
US5158572A (en) | 1987-09-10 | 1992-10-27 | Nielsen James Mchenry | Multifocal intraocular lens |
US4881804A (en) | 1987-11-12 | 1989-11-21 | Cohen Allen L | Multifocal phase plate with a pure refractive portion |
US4888012A (en) | 1988-01-14 | 1989-12-19 | Gerald Horn | Intraocular lens assemblies |
GB2215076A (en) | 1988-02-02 | 1989-09-13 | Dennis T Grendahl | Intraocular lens having a hard optic and a soft skirt |
IT1215851B (en) | 1988-02-11 | 1990-02-22 | Renato Liffredo | INTRAOCULAR LENS WITH CHROMATIC CORRECTION AND ABSORPTION DIAGRAM. |
CA1316728C (en) | 1988-04-01 | 1993-04-27 | Michael J. Simpson | Multi-focal diffractive ophthalmic lenses |
FR2631228B1 (en) | 1988-05-11 | 1990-08-10 | Domilens Laboratoires | INTRA-EYE IMPLANT OF PREVIOUS CHAMBER |
US4932970A (en) | 1988-05-17 | 1990-06-12 | Allergan, Inc. | Ophthalmic lens |
CA1316727C (en) | 1988-07-20 | 1993-04-27 | Allen L. Cohen | Multifocal optical device |
FR2642854B1 (en) | 1989-02-03 | 1991-05-03 | Essilor Int | OPTICAL LENS WITH SIMULTANEOUS VISION FOR PRESBYTIA CORRECTION |
US6197059B1 (en) * | 1990-04-27 | 2001-03-06 | Medevec Licensing, B.V. | Accomodating intraocular lens |
US5147397A (en) | 1990-07-03 | 1992-09-15 | Allergan, Inc. | Intraocular lens and method for making same |
US5171266A (en) | 1990-09-04 | 1992-12-15 | Wiley Robert G | Variable power intraocular lens with astigmatism correction |
US5173723A (en) | 1990-10-02 | 1992-12-22 | Volk Donald A | Aspheric ophthalmic accommodating lens design for intraocular lens and contact lens |
US5260727A (en) | 1990-10-22 | 1993-11-09 | Oksman Henry C | Wide depth of focus intraocular and contact lenses |
US5258025A (en) | 1990-11-21 | 1993-11-02 | Fedorov Svjatoslav N | Corrective intraocular lens |
US5326347A (en) | 1991-08-12 | 1994-07-05 | Cumming J Stuart | Intraocular implants |
US5578081A (en) | 1991-11-12 | 1996-11-26 | Henry H. McDonald | Eye muscle responsive artificial lens unit |
NL9200400A (en) | 1992-03-04 | 1993-10-01 | Jose Jorge Pavlotzky Handelend | BIFOCAL CONTACT LENS, AND METHOD FOR MANUFACTURING SUCH CONTACT LENSES |
US5354335A (en) | 1993-02-04 | 1994-10-11 | Isaac Lipshitz | Intraocular insert for implantation in the human eye |
US6322589B1 (en) * | 1995-10-06 | 2001-11-27 | J. Stuart Cumming | Intraocular lenses with fixated haptics |
US5684560A (en) | 1995-05-04 | 1997-11-04 | Johnson & Johnson Vision Products, Inc. | Concentric ring single vision lens designs |
US5682223A (en) | 1995-05-04 | 1997-10-28 | Johnson & Johnson Vision Products, Inc. | Multifocal lens designs with intermediate optical powers |
DE69728144T2 (en) * | 1996-05-17 | 2005-03-03 | Helmut Payer | EYE IMPLANT |
US5928283A (en) | 1997-06-26 | 1999-07-27 | Visioncare Ltd | Telescopic device for an intraocular lens |
US5814103A (en) | 1998-01-15 | 1998-09-29 | Visioncare Ltd. | Intraocular lens and telescope with mating fasteners |
DE60029102T2 (en) * | 1999-04-30 | 2007-01-11 | Advanced Medical Optics, Inc., Santa Ana | MOVABLE INTRAOCULAR LENSES |
ATE339933T1 (en) * | 1999-12-14 | 2006-10-15 | Hans-Georg Dr Rer Nat Boehm | FOCUSING INTRAOCULAR LENS |
FR2804860B1 (en) * | 2000-02-16 | 2002-04-12 | Humanoptics Ag | ACCOMODATIVE CRYSTALLINE IMPLANT |
US6797004B1 (en) * | 2000-03-02 | 2004-09-28 | Advanced Medical Optics, Inc. | Holders for intraocular lenses |
-
2000
- 2000-03-09 US US09/522,326 patent/US6551354B1/en not_active Expired - Lifetime
-
2001
- 2001-03-06 AU AU2001247288A patent/AU2001247288A1/en not_active Abandoned
- 2001-03-06 EP EP01920212A patent/EP1292247B1/en not_active Expired - Lifetime
- 2001-03-06 BR BR0109063-1A patent/BR0109063A/en not_active Application Discontinuation
- 2001-03-06 DE DE60126489T patent/DE60126489T2/en not_active Expired - Lifetime
- 2001-03-06 AT AT01920212T patent/ATE353198T1/en not_active IP Right Cessation
- 2001-03-06 CA CA002401972A patent/CA2401972C/en not_active Expired - Lifetime
- 2001-03-06 JP JP2001564696A patent/JP3958576B2/en not_active Expired - Fee Related
- 2001-03-06 WO PCT/US2001/007062 patent/WO2001066042A1/en active IP Right Grant
-
2002
- 2002-12-23 US US10/329,076 patent/US20030109925A1/en not_active Abandoned
Patent Citations (100)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US1483509A (en) * | 1921-05-05 | 1924-02-12 | Franklin Optical Company | Process of making fused bifocal lenses |
US2129305A (en) * | 1936-08-21 | 1938-09-06 | Feinbloom William | Contact lens |
US2274142A (en) * | 1940-01-15 | 1942-02-24 | Revalens Co | Multifocal ophthalmic lens |
US2405989A (en) * | 1941-08-12 | 1946-08-20 | Beach Lens Corp | Lens |
US2511517A (en) * | 1947-01-31 | 1950-06-13 | Bell & Howell Co | Method of producing optical glass of varied refractive index |
US3031927A (en) * | 1958-03-03 | 1962-05-01 | Plastic Contact Lens Company | Bifocal corneal contact lens |
US3034403A (en) * | 1959-04-03 | 1962-05-15 | Neefe Hamilton Res Company | Contact lens of apparent variable light absorption |
US3227507A (en) * | 1961-08-16 | 1966-01-04 | Feinbloom William | Corneal contact lens having inner ellipsoidal surface |
US3339997A (en) * | 1962-07-30 | 1967-09-05 | Plastic Contact Lens Company | Bifocal ophthalmic lens having different color distance and near vision zones |
US3420006A (en) * | 1964-01-27 | 1969-01-07 | Howard J Barnett | Apparatus for grinding multifocal lens |
US3431327A (en) * | 1964-08-31 | 1969-03-04 | George F Tsuetaki | Method of making a bifocal contact lens with an embedded metal weight |
US3693301A (en) * | 1970-05-27 | 1972-09-26 | Anvar | Method for producing optical elements with aspherical surfaces |
US3932148A (en) * | 1975-01-21 | 1976-01-13 | Criterion Manufacturing Company, Inc. | Method and apparatus for making complex aspheric optical surfaces |
US4162122A (en) * | 1977-09-14 | 1979-07-24 | Cohen Allen L | Zonal bifocal contact lens |
US4210391A (en) * | 1977-09-14 | 1980-07-01 | Cohen Allen L | Multifocal zone plate |
US4195919A (en) * | 1977-10-31 | 1980-04-01 | Shelton William A | Contact lens with reduced spherical aberration for aphakic eyes |
US4315673A (en) * | 1978-04-06 | 1982-02-16 | Optische Werke G. Rodenstock | Progressive power ophthalmic lens |
US4199231A (en) * | 1978-08-21 | 1980-04-22 | Evans Carl H | Hydrogel contact lens |
US4253199A (en) * | 1978-09-25 | 1981-03-03 | Surgical Design Corporation | Surgical method and apparatus for implants for the eye |
US4338005A (en) * | 1978-12-18 | 1982-07-06 | Cohen Allen L | Multifocal phase place |
US4340283A (en) * | 1978-12-18 | 1982-07-20 | Cohen Allen L | Phase shift multifocal zone plate |
US4254509A (en) * | 1979-04-09 | 1981-03-10 | Tennant Jerald L | Accommodating intraocular implant |
US4274717A (en) * | 1979-05-18 | 1981-06-23 | Younger Manufacturing Company | Ophthalmic progressive power lens and method of making same |
US4316293A (en) * | 1979-08-27 | 1982-02-23 | Bayers Jon Herbert | Flexible intraocular lens |
US4377329A (en) * | 1980-02-26 | 1983-03-22 | Stanley Poler | Contact lens or the like |
US4370760A (en) * | 1981-03-25 | 1983-02-01 | Kelman Charles D | Anterior chamber intraocular lens |
US4402579A (en) * | 1981-07-29 | 1983-09-06 | Lynell Medical Technology Inc. | Contact-lens construction |
US5776191A (en) * | 1982-02-05 | 1998-07-07 | Staar Surgical Company | Fixation system for intraocular lens structures |
US4404694A (en) * | 1982-03-18 | 1983-09-20 | Kelman Charles D | Intraocular lens |
US4504982A (en) * | 1982-08-05 | 1985-03-19 | Optical Radiation Corporation | Aspheric intraocular lens |
US4573775A (en) * | 1982-08-19 | 1986-03-04 | Vistakon, Inc. | Bifocal contact lens |
US4641934A (en) * | 1982-09-29 | 1987-02-10 | Pilkington P.E. Limited | Ophthalmic lens with diffractive power |
US4890913A (en) * | 1982-10-13 | 1990-01-02 | Carle John T De | Zoned multi-focal contact lens |
US4637697A (en) * | 1982-10-27 | 1987-01-20 | Pilkington P.E. Limited | Multifocal contact lenses utilizing diffraction and refraction |
US4580882A (en) * | 1983-04-21 | 1986-04-08 | Benjamin Nuchman | Continuously variable contact lens |
US4813955A (en) * | 1983-09-07 | 1989-03-21 | Manfred Achatz | Multifocal, especially bifocal, intraocular, artificial ophthalmic lens |
US4636049A (en) * | 1983-09-20 | 1987-01-13 | University Optical Products Co. | Concentric bifocal contact lens |
US4687484A (en) * | 1983-12-12 | 1987-08-18 | Kaplan Linda J | Anterior chamber intraocular lens |
US4596578A (en) * | 1984-01-30 | 1986-06-24 | Kelman Charles D | Intraocular lens with miniature optic |
US4636211A (en) * | 1984-03-13 | 1987-01-13 | Nielsen J Mchenry | Bifocal intra-ocular lens |
US4720286A (en) * | 1984-07-20 | 1988-01-19 | Bailey Kelvin E | Multifocus intraocular lens |
US4759762A (en) * | 1985-03-08 | 1988-07-26 | Grendahl Dennis T | Accommodating lens |
US4693572A (en) * | 1985-06-03 | 1987-09-15 | Fused Kontacts Of Chicago, Inc. | Monocentric bifocal corneal contact lens |
US4752123A (en) * | 1985-11-19 | 1988-06-21 | University Optical Products Co. | Concentric bifocal contact lens with two distance power regions |
US4890912A (en) * | 1986-01-24 | 1990-01-02 | Rients Visser | Trifocal eye-contact lens |
US4938583A (en) * | 1986-06-02 | 1990-07-03 | Miller Gregory N | Contact lens and method of making same |
US5192318A (en) * | 1986-06-05 | 1993-03-09 | Schneider Richard T | One-piece bifocal intraocular lens construction |
US4676792A (en) * | 1986-08-26 | 1987-06-30 | Donald Praeger | Method and artificial intraocular lens device for the phakic treatment of myopia |
US4842601A (en) * | 1987-05-18 | 1989-06-27 | Smith S Gregory | Accommodating intraocular lens and method of implanting and using same |
US5201762A (en) * | 1987-05-20 | 1993-04-13 | Hauber Frederick A | Intraocular archromatic lens |
US5657108A (en) * | 1987-06-01 | 1997-08-12 | Portney; Valdemar | Multifocal ophthalmic lens |
US5521656A (en) * | 1987-06-01 | 1996-05-28 | Portney; Valdemar | Method of making an ophthalmic lens |
US5225858A (en) * | 1987-06-01 | 1993-07-06 | Valdemar Portney | Multifocal ophthalmic lens |
US4898461A (en) * | 1987-06-01 | 1990-02-06 | Valdemar Portney | Multifocal ophthalmic lens |
US4769033A (en) * | 1987-07-02 | 1988-09-06 | Nordan Lee T | Intraocular multifocal lens |
US5019099A (en) * | 1987-07-02 | 1991-05-28 | Nordan Lee T | Intraocular multifocal lens method for correcting the aphakic eye |
US4932968A (en) * | 1987-07-07 | 1990-06-12 | Caldwell Delmar R | Intraocular prostheses |
US4906246A (en) * | 1987-08-24 | 1990-03-06 | Grendahl Dennis T | Cylindrically segmented zone of focus artificial hydrogel lens |
US4917681A (en) * | 1987-08-24 | 1990-04-17 | Nordan Lee T | Intraocular multifocal lens |
US4919663A (en) * | 1987-08-24 | 1990-04-24 | Grendahl Dennis T | Laminated zone of focus artificial hydrogel lens |
US4921496A (en) * | 1987-08-24 | 1990-05-01 | Grendahl Dennis T | Radially segemented zone of focus artificial hydrogel lens |
US5047052A (en) * | 1987-11-06 | 1991-09-10 | Seymour Dubroff | Anterior chamber intraocular lens with four point fixation |
US5000559A (en) * | 1988-02-29 | 1991-03-19 | Nikon Corporation | Ophthalmic lenses having progressively variable refracting power |
US5089024A (en) * | 1988-04-19 | 1992-02-18 | Storz Instrument Company | Multi-focal intraocular lens |
US4923296A (en) * | 1988-07-14 | 1990-05-08 | Erickson Paul M | Oriented simultaneous vision bifocal contact lenses or the like utilizing introaocular suppression of blur |
US5192317A (en) * | 1988-07-26 | 1993-03-09 | Irvin Kalb | Multi focal intra-ocular lens |
US4830481A (en) * | 1988-08-12 | 1989-05-16 | Minnesota Mining And Manufacturing Company | Multifocal diffractive lens |
US4932966A (en) * | 1988-08-15 | 1990-06-12 | Storz Instrument Company | Accommodating intraocular lens |
US4994082A (en) * | 1988-09-09 | 1991-02-19 | Ophthalmic Ventures Limited Partnership | Accommodating intraocular lens |
US4990159A (en) * | 1988-12-02 | 1991-02-05 | Kraff Manus C | Intraocular lens apparatus with haptics of varying cross-sectional areas |
US4892543A (en) * | 1989-02-02 | 1990-01-09 | Turley Dana F | Intraocular lens providing accomodation |
US5019098A (en) * | 1989-05-19 | 1991-05-28 | Essilor International Cie Generale D'optique | Sight-correcting optical component such as an intra-ocular implant or contact lens |
US4955902A (en) * | 1989-11-13 | 1990-09-11 | Kelman Charles D | Decentered intraocular lens |
US5002382A (en) * | 1989-12-07 | 1991-03-26 | Leonard Seidner | Multifocal corneal contact lenses |
US5496366A (en) * | 1990-04-27 | 1996-03-05 | Cumming; J. Stuart | Accommodating intraocular lens |
US5026396A (en) * | 1990-05-07 | 1991-06-25 | Darin John J | Two-piece intraocular lens |
US5096285A (en) * | 1990-05-14 | 1992-03-17 | Iolab Corporation | Multifocal multizone diffractive ophthalmic lenses |
US5112351A (en) * | 1990-10-12 | 1992-05-12 | Ioptex Research Inc. | Multifocal intraocular lenses |
US5766244A (en) * | 1991-05-23 | 1998-06-16 | Binder; Helmut | Intraocular artificial lens and method for fabricating same |
US5652014A (en) * | 1991-08-16 | 1997-07-29 | Galin; Miles A. | Medicament coated refractive anterior chamber ocular implant |
US5275623A (en) * | 1991-11-18 | 1994-01-04 | Faezeh Sarfarazi | Elliptical accommodative intraocular lens for small incision surgery |
US5443506A (en) * | 1992-11-18 | 1995-08-22 | Garabet; Antoine L. | Lens with variable optical properties |
US5480428A (en) * | 1993-04-22 | 1996-01-02 | Mezhotraslevoi Nauchno-Tekhnichesky Komplex "Mikrokhirurgia Glaza" | Corrective intraocular lens |
US5489302A (en) * | 1994-05-24 | 1996-02-06 | Skottun; Bernt C. | Accommodating intraocular lens |
US5628796A (en) * | 1994-07-04 | 1997-05-13 | Suzuki; Taketoshi | Intraocular lens |
US5609630A (en) * | 1994-08-22 | 1997-03-11 | Philippe Crozafon | Intraocular implant |
US6013101A (en) * | 1994-11-21 | 2000-01-11 | Acuity (Israel) Limited | Accommodating intraocular lens implant |
US5549760A (en) * | 1994-12-01 | 1996-08-27 | White Consolidated Industries, Inc. | Mounting device for dishwasher insulation |
US6387126B1 (en) * | 1995-02-15 | 2002-05-14 | J. Stuart Cumming | Accommodating intraocular lens having T-shaped haptics |
US5628795A (en) * | 1995-03-15 | 1997-05-13 | Langerman David W | Spare parts for use in ophthalmic surgical procedures |
US5652638A (en) * | 1995-05-04 | 1997-07-29 | Johnson & Johnson Vision Products, Inc. | Concentric annular ring lens designs for astigmatism |
US5607472A (en) * | 1995-05-09 | 1997-03-04 | Emory University | Intraocular lens for restoring accommodation and allows adjustment of optical power |
US5769890A (en) * | 1997-01-16 | 1998-06-23 | Henry H. McDonald | Placement of second artificial lens in eye, to correct for optical defects of first artificial lens in eye |
US5769890B1 (en) * | 1997-01-16 | 2000-09-05 | Surgical Concepts Inc | Placement of second artificial lens in eye to correct for optical defects of first artificial lens in eye |
US6096078A (en) * | 1997-10-20 | 2000-08-01 | Surgical Concepts, Inc. | Accommodative lens implantation |
US5876442A (en) * | 1998-01-15 | 1999-03-02 | Visioncare Ltd. | Intraocular lens implant with telescope support |
US6186148B1 (en) * | 1998-02-04 | 2001-02-13 | Kiyoshi Okada | Prevention of posterior capsular opacification |
US6176878B1 (en) * | 1998-12-17 | 2001-01-23 | Allergan Sales, Inc. | Accommodating intraocular lens |
US6224628B1 (en) * | 1999-04-23 | 2001-05-01 | Thinoptx, Inc. | Haptics for an intraocular lens |
US6217612B1 (en) * | 1999-09-10 | 2001-04-17 | Randall Woods | Intraocular lens implant having eye accommodating capabilities |
Cited By (123)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8425597B2 (en) | 1999-04-30 | 2013-04-23 | Abbott Medical Optics Inc. | Accommodating intraocular lenses |
US9814570B2 (en) | 1999-04-30 | 2017-11-14 | Abbott Medical Optics Inc. | Ophthalmic lens combinations |
US7226478B2 (en) * | 2001-01-25 | 2007-06-05 | Visiogen, Inc. | Optic configuration for intraocular lens system |
US20020116057A1 (en) * | 2001-01-25 | 2002-08-22 | Ting Albert C. | Optic configuration for intraocular lens system |
US6786934B2 (en) | 2001-01-25 | 2004-09-07 | Visiogen, Inc. | Biasing element for intraocular lens system |
US20030078657A1 (en) * | 2001-01-25 | 2003-04-24 | Gholam-Reza Zadno-Azizi | Materials for use in accommodating intraocular lens system |
US7776088B2 (en) | 2001-08-31 | 2010-08-17 | Powervision, Inc. | Intraocular lens system and method for power adjustment |
US8992609B2 (en) | 2001-08-31 | 2015-03-31 | Powervision, Inc. | Intraocular lens system and method for power adjustment |
US20030109926A1 (en) * | 2001-12-10 | 2003-06-12 | Valdemar Portney | Accommodating intraocular lens |
US7097660B2 (en) | 2001-12-10 | 2006-08-29 | Valdemar Portney | Accommodating intraocular lens |
US9504560B2 (en) | 2002-01-14 | 2016-11-29 | Abbott Medical Optics Inc. | Accommodating intraocular lens with outer support structure |
US8343216B2 (en) | 2002-01-14 | 2013-01-01 | Abbott Medical Optics Inc. | Accommodating intraocular lens with outer support structure |
US10045844B2 (en) | 2002-02-02 | 2018-08-14 | Powervision, Inc. | Post-implant accommodating lens modification |
US9456895B2 (en) | 2002-02-02 | 2016-10-04 | Powervision, Inc. | Accommodating intraocular lens |
US20170020662A1 (en) * | 2002-02-02 | 2017-01-26 | John H. Shadduck | Accommodating intraocular lenses |
US10433950B2 (en) * | 2002-02-02 | 2019-10-08 | Powervision, Inc. | Accommodating intraocular lenses |
US8048155B2 (en) | 2002-02-02 | 2011-11-01 | Powervision, Inc. | Intraocular implant devices |
US8425599B2 (en) | 2002-02-02 | 2013-04-23 | Powervision, Inc. | Accommodating intraocular lenses and methods of use |
US10206773B2 (en) | 2002-12-05 | 2019-02-19 | Johnson & Johnson Surgical Vision, Inc. | Accommodating intraocular lens and method of manufacture thereof |
US9271830B2 (en) | 2002-12-05 | 2016-03-01 | Abbott Medical Optics Inc. | Accommodating intraocular lens and method of manufacture thereof |
US20070106377A1 (en) * | 2002-12-12 | 2007-05-10 | Powervision, Inc. | Accommodating intraocular lens system having spherical aberration compensation and method |
US9872762B2 (en) | 2002-12-12 | 2018-01-23 | Powervision, Inc. | Accommodating intraocular lenses |
US9795473B2 (en) | 2002-12-12 | 2017-10-24 | Powervision, Inc. | Accommodating intraocular lenses |
US20080046075A1 (en) * | 2002-12-12 | 2008-02-21 | Esch Victor C | Accommodating Intraocular Lens System and Method |
US20080046074A1 (en) * | 2002-12-12 | 2008-02-21 | Smith David J | Accommodating Intraocular Lens System Having Spherical Aberration Compensation and Method |
US10835373B2 (en) | 2002-12-12 | 2020-11-17 | Alcon Inc. | Accommodating intraocular lenses and methods of use |
US9855137B2 (en) | 2002-12-12 | 2018-01-02 | Powervision, Inc. | Accommodating intraocular lenses and methods of use |
US20080015689A1 (en) * | 2002-12-12 | 2008-01-17 | Victor Esch | Accommodating Intraocular Lens System and Method |
US9277987B2 (en) | 2002-12-12 | 2016-03-08 | Powervision, Inc. | Accommodating intraocular lenses |
US11751991B2 (en) | 2002-12-12 | 2023-09-12 | Alcon Inc. | Accommodating intraocular lenses and methods of use |
US20070213817A1 (en) * | 2002-12-12 | 2007-09-13 | Victor Esch | Accommodating intraocular lens having peripherally actuated deflectable surface and method |
US8328869B2 (en) | 2002-12-12 | 2012-12-11 | Powervision, Inc. | Accommodating intraocular lenses and methods of use |
US20040190153A1 (en) * | 2002-12-12 | 2004-09-30 | Powervision | Lens system and method for power adjustment using externally actuated micropumps |
US8361145B2 (en) | 2002-12-12 | 2013-01-29 | Powervision, Inc. | Accommodating intraocular lens system having circumferential haptic support and method |
US20070010880A1 (en) * | 2002-12-12 | 2007-01-11 | Powervision, Inc. | Methods of adjusting the power of an intraocular lens |
US8454688B2 (en) | 2002-12-12 | 2013-06-04 | Powervision, Inc. | Accommodating intraocular lens having peripherally actuated deflectable surface and method |
US7238201B2 (en) | 2003-02-13 | 2007-07-03 | Visiogen, Inc. | Accommodating intraocular lens system with enhanced range of motion |
US20040162612A1 (en) * | 2003-02-13 | 2004-08-19 | Valdemar Portney | Accommodating intraocular lens system with enhanced range of motion |
US8303656B2 (en) | 2003-03-06 | 2012-11-06 | Powervision, Inc. | Adaptive optic lens and method of making |
US10534113B2 (en) | 2003-03-06 | 2020-01-14 | Powervision, Inc. | Adaptive optic lens and method of making |
US9198752B2 (en) | 2003-12-15 | 2015-12-01 | Abbott Medical Optics Inc. | Intraocular lens implant having posterior bendable optic |
US20070191941A1 (en) * | 2004-06-03 | 2007-08-16 | Burkhard Dick | Capsular equatorial ring |
US9872763B2 (en) | 2004-10-22 | 2018-01-23 | Powervision, Inc. | Accommodating intraocular lenses |
US8377123B2 (en) | 2004-11-10 | 2013-02-19 | Visiogen, Inc. | Method of implanting an intraocular lens |
US9636213B2 (en) * | 2005-09-30 | 2017-05-02 | Abbott Medical Optics Inc. | Deformable intraocular lenses and lens systems |
US20070078515A1 (en) * | 2005-09-30 | 2007-04-05 | Brady Daniel G | Deformable intraocular lenses and lens systems |
US20070244560A1 (en) * | 2006-04-12 | 2007-10-18 | Alexei Ossipov | Intraocular lens with distortion free valve |
US20070260308A1 (en) * | 2006-05-02 | 2007-11-08 | Alcon, Inc. | Accommodative intraocular lens system |
US20080125790A1 (en) * | 2006-11-29 | 2008-05-29 | George Tsai | Apparatus and methods for compacting an intraocular lens |
US8403984B2 (en) | 2006-11-29 | 2013-03-26 | Visiogen, Inc. | Apparatus and methods for compacting an intraocular lens |
US10368979B2 (en) | 2006-12-19 | 2019-08-06 | Powervision, Inc. | Accommodating intraocular lenses |
US20090018652A1 (en) * | 2006-12-22 | 2009-01-15 | Amo Groningen Bv | Accommodating intraocular lenses and associated systems, frames, and methods |
US7871437B2 (en) | 2006-12-22 | 2011-01-18 | Amo Groningen B.V. | Accommodating intraocular lenses and associated systems, frames, and methods |
US8182531B2 (en) | 2006-12-22 | 2012-05-22 | Amo Groningen B.V. | Accommodating intraocular lenses and associated systems, frames, and methods |
US8496701B2 (en) | 2006-12-22 | 2013-07-30 | Amo Groningen B.V. | Accommodating intraocular lenses and associated systems, frames, and methods |
US9039760B2 (en) | 2006-12-29 | 2015-05-26 | Abbott Medical Optics Inc. | Pre-stressed haptic for accommodating intraocular lens |
US8158712B2 (en) | 2007-02-21 | 2012-04-17 | Powervision, Inc. | Polymeric materials suitable for ophthalmic devices and methods of manufacture |
CN102727325A (en) * | 2007-05-29 | 2012-10-17 | S·J.·戴尔 | Accommodative intraocular lens having a haptic plate |
US8968396B2 (en) | 2007-07-23 | 2015-03-03 | Powervision, Inc. | Intraocular lens delivery systems and methods of use |
US10390937B2 (en) | 2007-07-23 | 2019-08-27 | Powervision, Inc. | Accommodating intraocular lenses |
US8314927B2 (en) | 2007-07-23 | 2012-11-20 | Powervision, Inc. | Systems and methods for testing intraocular lenses |
US11759313B2 (en) | 2007-07-23 | 2023-09-19 | Alcon Inc. | Lens delivery system |
US10350060B2 (en) | 2007-07-23 | 2019-07-16 | Powervision, Inc. | Lens delivery system |
US9855139B2 (en) | 2007-07-23 | 2018-01-02 | Powervision, Inc. | Intraocular lens delivery systems and methods of use |
US8956408B2 (en) | 2007-07-23 | 2015-02-17 | Powervision, Inc. | Lens delivery system |
US9968441B2 (en) | 2008-03-28 | 2018-05-15 | Johnson & Johnson Surgical Vision, Inc. | Intraocular lens having a haptic that includes a cap |
US9610155B2 (en) | 2008-07-23 | 2017-04-04 | Powervision, Inc. | Intraocular lens loading systems and methods of use |
US11166808B2 (en) | 2009-01-09 | 2021-11-09 | Alcon Inc. | Accommodating intraocular lenses and methods of use |
US10357356B2 (en) | 2009-01-09 | 2019-07-23 | Powervision, Inc. | Accommodating intraocular lenses and methods of use |
US10299913B2 (en) | 2009-01-09 | 2019-05-28 | Powervision, Inc. | Accommodating intraocular lenses and methods of use |
US9011532B2 (en) | 2009-06-26 | 2015-04-21 | Abbott Medical Optics Inc. | Accommodating intraocular lenses |
US10052194B2 (en) | 2009-06-26 | 2018-08-21 | Johnson & Johnson Surgical Vision, Inc. | Accommodating intraocular lenses |
US10105215B2 (en) | 2009-08-03 | 2018-10-23 | Johnson & Johnson Surgical Vision, Inc. | Intraocular lens and methods for providing accommodative vision |
US9603703B2 (en) | 2009-08-03 | 2017-03-28 | Abbott Medical Optics Inc. | Intraocular lens and methods for providing accommodative vision |
US8447086B2 (en) | 2009-08-31 | 2013-05-21 | Powervision, Inc. | Lens capsule size estimation |
US20110071628A1 (en) * | 2009-09-24 | 2011-03-24 | Rainbow Medical Ltd. | Accommodative intraocular lens |
US20120310341A1 (en) * | 2009-11-17 | 2012-12-06 | Akkolens International B.V. | Accommodative Intraocular Lens Driven by Ciliary Mass |
US9114005B2 (en) * | 2009-11-17 | 2015-08-25 | Akkolens International B.V. | Accommodative intraocular lens driven by ciliary mass |
US11737862B2 (en) | 2010-02-23 | 2023-08-29 | Alcon Inc. | Fluid for accommodating intraocular lenses |
US8900298B2 (en) | 2010-02-23 | 2014-12-02 | Powervision, Inc. | Fluid for accommodating intraocular lenses |
US10980629B2 (en) | 2010-02-23 | 2021-04-20 | Alcon Inc. | Fluid for accommodating intraocular lenses |
US9918830B2 (en) | 2010-06-21 | 2018-03-20 | James Stuart Cumming | Foldable intraocular lens with rigid haptics |
US10736732B2 (en) | 2010-06-21 | 2020-08-11 | James Stuart Cumming | Intraocular lens with longitudinally rigid plate haptic |
US9585745B2 (en) | 2010-06-21 | 2017-03-07 | James Stuart Cumming | Foldable intraocular lens with rigid haptics |
US9211186B2 (en) | 2010-06-21 | 2015-12-15 | James Stuart Cumming | Semi-rigid framework for a plate haptic intraocular lens |
US9283070B2 (en) | 2010-06-21 | 2016-03-15 | James Stuart Cumming | Vitreous compressing plate haptic |
US9034036B2 (en) | 2010-06-21 | 2015-05-19 | James Stuart Cumming | Seamless-vision, tilted intraocular lens |
US8764823B2 (en) | 2010-06-21 | 2014-07-01 | James Stuart Cumming | Semi-rigid framework for a plate haptic accommodating intraocular lens |
US9655716B2 (en) | 2010-06-21 | 2017-05-23 | James Stuart Cumming | Semi-rigid framework for a plate haptic accommodating intraocular lens |
US10595989B2 (en) | 2010-07-09 | 2020-03-24 | Powervision, Inc. | Intraocular lens delivery devices and methods of use |
US9693858B2 (en) | 2010-07-09 | 2017-07-04 | Powervision, Inc. | Intraocular lens delivery devices and methods of use |
US9044317B2 (en) | 2010-07-09 | 2015-06-02 | Powervision, Inc. | Intraocular lens delivery devices and methods of use |
US8668734B2 (en) | 2010-07-09 | 2014-03-11 | Powervision, Inc. | Intraocular lens delivery devices and methods of use |
US11779456B2 (en) | 2010-07-09 | 2023-10-10 | Alcon Inc. | Intraocular lens delivery devices and methods of use |
US11147663B2 (en) | 2011-01-31 | 2021-10-19 | James Stuart Cumming | Intraocular lens |
US9730786B2 (en) | 2011-01-31 | 2017-08-15 | James Stuart Cumming | Anterior capsule deflector ridge |
US8734512B2 (en) | 2011-05-17 | 2014-05-27 | James Stuart Cumming | Biased accommodating intraocular lens |
US11484402B2 (en) | 2011-11-08 | 2022-11-01 | Alcon Inc. | Accommodating intraocular lenses |
US10433949B2 (en) | 2011-11-08 | 2019-10-08 | Powervision, Inc. | Accommodating intraocular lenses |
US9987125B2 (en) | 2012-05-02 | 2018-06-05 | Johnson & Johnson Surgical Vision, Inc. | Intraocular lens with shape changing capability to provide enhanced accomodation and visual acuity |
US9295545B2 (en) | 2012-06-05 | 2016-03-29 | James Stuart Cumming | Intraocular lens |
US10463475B2 (en) | 2012-06-05 | 2019-11-05 | James Stuart Cumming | Intraocular lens |
US9295544B2 (en) | 2012-06-05 | 2016-03-29 | James Stuart Cumming | Intraocular lens |
US9358101B2 (en) | 2012-06-05 | 2016-06-07 | James Stuart Cumming | Intraocular lens |
US10258462B2 (en) | 2012-12-26 | 2019-04-16 | Rainbow Medical Ltd. | Accommodative intraocular lens |
US10646330B2 (en) | 2012-12-26 | 2020-05-12 | Rainbow Medical Ltd. | Accommodative intraocular lens |
US9925039B2 (en) | 2012-12-26 | 2018-03-27 | Rainbow Medical Ltd. | Accommodative intraocular lens |
US11278393B2 (en) | 2012-12-26 | 2022-03-22 | Rainbow Medical Ltd. | Accommodative intraocular lens |
US11793627B2 (en) | 2013-03-15 | 2023-10-24 | Alcon Inc. | Intraocular lens storage and loading devices and methods of use |
US11071622B2 (en) | 2013-03-15 | 2021-07-27 | Alcon Inc. | Intraocular lens storage and loading devices and methods of use |
US10195020B2 (en) | 2013-03-15 | 2019-02-05 | Powervision, Inc. | Intraocular lens storage and loading devices and methods of use |
US9295546B2 (en) | 2013-09-24 | 2016-03-29 | James Stuart Cumming | Anterior capsule deflector ridge |
US9629711B2 (en) | 2013-12-30 | 2017-04-25 | James Stuart Cumming | Intraocular lens |
US9655717B2 (en) | 2013-12-30 | 2017-05-23 | James Stuart Cumming | Semi-flexible posteriorly vaulted acrylic intraocular lens for the treatment of presbyopia |
US9615916B2 (en) | 2013-12-30 | 2017-04-11 | James Stuart Cumming | Intraocular lens |
US9351825B2 (en) | 2013-12-30 | 2016-05-31 | James Stuart Cumming | Semi-flexible posteriorly vaulted acrylic intraocular lens for the treatment of presbyopia |
US12059342B2 (en) | 2015-06-10 | 2024-08-13 | Alcon Inc. | Intraocular lens materials and components |
US11426270B2 (en) | 2015-11-06 | 2022-08-30 | Alcon Inc. | Accommodating intraocular lenses and methods of manufacturing |
US10327886B2 (en) | 2016-06-01 | 2019-06-25 | Rainbow Medical Ltd. | Accomodative intraocular lens |
US10441411B2 (en) | 2016-12-29 | 2019-10-15 | Rainbow Medical Ltd. | Accommodative intraocular lens |
US11707354B2 (en) | 2017-09-11 | 2023-07-25 | Amo Groningen B.V. | Methods and apparatuses to increase intraocular lenses positional stability |
US11471272B2 (en) | 2019-10-04 | 2022-10-18 | Alcon Inc. | Adjustable intraocular lenses and methods of post-operatively adjusting intraocular lenses |
US11660182B2 (en) | 2019-10-04 | 2023-05-30 | Alcon Inc. | Adjustable intraocular lenses and methods of post-operatively adjusting intraocular lenses |
Also Published As
Publication number | Publication date |
---|---|
EP1292247A1 (en) | 2003-03-19 |
JP2003525694A (en) | 2003-09-02 |
CA2401972A1 (en) | 2001-09-13 |
WO2001066042A1 (en) | 2001-09-13 |
DE60126489D1 (en) | 2007-03-22 |
US6551354B1 (en) | 2003-04-22 |
ATE353198T1 (en) | 2007-02-15 |
EP1292247B1 (en) | 2007-02-07 |
BR0109063A (en) | 2002-12-10 |
JP3958576B2 (en) | 2007-08-15 |
DE60126489T2 (en) | 2007-11-15 |
CA2401972C (en) | 2009-01-20 |
AU2001247288A1 (en) | 2001-09-17 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
US6551354B1 (en) | Accommodating intraocular lens | |
US7326246B2 (en) | Accommodating intraocular lens with elongated suspension structure | |
US6797004B1 (en) | Holders for intraocular lenses | |
EP1304979B1 (en) | Accommodating intraocular lens with suspension structure | |
CA2350795C (en) | Accommodating multifocal intraocular lens | |
US7025783B2 (en) | Accommodating intraocular lens with integral capsular bag ring | |
EP1176930B1 (en) | Intraocular lens combinations | |
EP1278483B1 (en) | Accommodating, reduced add power multifocal intraocular lenses | |
US6406494B1 (en) | Moveable intraocular lens | |
EP1227773B1 (en) | Intraocular lens system | |
US20020120329A1 (en) | Moveable intraocular lenses and combinations of intraocular lenses | |
US20040054408A1 (en) | Accommodating intraocular lens assembly with aspheric optic design | |
US20030018384A1 (en) | Accommodative intraocular lens | |
AU2001259360A1 (en) | Accommodating, reduced add power multifocal intraocular lenses | |
EP1185219B1 (en) | Moveable intraocular lens |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
AS | Assignment |
Owner name: ADVANCED MEDICAL OTPICS, INC., CALIFORNIA Free format text: ASSIGNMENT OF ASSIGNORS INTEREST;ASSIGNORS:ALLERGAN, INC.;ALLERGAN SALES, LLC;ALLERGAN PHARMACEUTICALS, INC.;AND OTHERS;REEL/FRAME:014217/0356 Effective date: 20030625 |
|
STCB | Information on status: application discontinuation |
Free format text: EXPRESSLY ABANDONED -- DURING EXAMINATION |