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US1704924A - Syringe cartridge - Google Patents

Syringe cartridge Download PDF

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Publication number
US1704924A
US1704924A US54644A US5464425A US1704924A US 1704924 A US1704924 A US 1704924A US 54644 A US54644 A US 54644A US 5464425 A US5464425 A US 5464425A US 1704924 A US1704924 A US 1704924A
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US
United States
Prior art keywords
plug
cartridge
pressure
syringe
wall
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
US54644A
Inventor
Roland C Rehm
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
COOK LAB Inc
COOK LABORATORIES Inc
Original Assignee
COOK LAB Inc
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Publication date
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Priority to US54644A priority Critical patent/US1704924A/en
Application granted granted Critical
Publication of US1704924A publication Critical patent/US1704924A/en
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Expired - Lifetime legal-status Critical Current

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/24Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/24Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
    • A61M2005/2403Ampoule inserted into the ampoule holder
    • A61M2005/2407Ampoule inserted into the ampoule holder from the rear
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/24Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
    • A61M2005/2403Ampoule inserted into the ampoule holder
    • A61M2005/2411Ampoule inserted into the ampoule holder from the front
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/315Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31511Piston or piston-rod constructions, e.g. connection of piston with piston-rod

Definitions

  • This invention relates to cartridges or medicament-dispensing packages for use as operative components of hypodermlc s inges.
  • the object is to provide a cartri ge with an improved piston plug adapted upon release of the applied operating pressure to eXert an action counter to that which would tend to produce back-suction.
  • Fig. 1 is a longitudinal section of a syringe containing said cartridge as an opera tive component thereof;
  • Fig. 2 is an enlarged view in longitudinal section of a fragment of the cartridge, showing the piston plug being forced forward by the syringe lunger;
  • Fig. 3 is a etailed perspective view of 20 the plston plug on an enlarged scale.
  • the illustrative cartridge comprising a glass tube 12 sealed by rubber plugs or stoppers 13 and 14, is shown in Fig. 1 in an instrument which in conjunction with the cartridge provides an operative syringe or injection-administering organization.
  • Said instrument comprises a cartridge-holder 5 having removable heads 6 and 7.
  • a slidable plunger rod- 8 having an enlarged inner end 9 adapted to enter the glass cartridge tube and drive the stopper 14 forward for ejecting the liquid contents of the cartridge through the in'ecting needle attached to the fore end o the instrument.
  • the rubber plug 14 which in this instance is a slidable piston plug as well as a sealing closure, is designed or constructed so that any distortion which the plug undergoes by plunger thrust during the fluid-ejecting operation will not cause a back-suction bywreflexing of the plug when the pressure on the hw cannot cause relative forward 2:1
  • the saidl plug 14 has an interior closed cavity 15 and a relativel thin front Wfall 16 exposed to the liquid in t e cartridge.
  • the back wall of the hollow plug and its annular wall around the cavity are relatively thick to provide a sufliciently firm plug to be compressed in the cartridge tube and which may be pushed forward by the plungerapplied against the back end of the plug.
  • the opportunity for distortion by plunger thrust in a manner which would cause back-suction by reflexing, ⁇ is minimized.
  • the fluid pressure in the cartridge acting against the resilient or flexible fore wall 16 will cause said wall to flex backward or bulge into the cavity, as indicated in Fig. 2; and when the applied pressure is released the reflexing of the wall in resuming its normal undistended position will be in a direction tending to continue the ejection' and thus have an effect contrary to a sucking-back tendency.
  • the wall 16 may be sufficiently thin to be quite flexible and to lprovide a pressure sensitive diaphragm which will be distended as soon as any pressure' is applied on the liquid and will relax immediately after the pressure ceases.
  • the described piston plug may be made in various ways, I contemplate making it by uniting two separate recessed or cupshaped sections as shown, their contacting ends being cemented or otherwise suitably joined.
  • the front section is ofC originally smaller diameter than the other, 95 so that the compression of the plug when inserted in the cartridge tube will not bow or improperly affect thc wall 1G, and also because it is deemed preferable to have the rear plllugereugageable section in tighter 1m engagement with the glass tube than the fore section.
  • the described piston plug may be considered as oneembodying an elastic closed hollow body adapted to be compressed in the tluid-ejccting operation, as manifested by contraction oi" the cavity, and which upon release of the pressure will expand toward the discharge end otl the cartridge.
  • a medicament dispensing package comprising, in combination, a tubular body; a plug scaling one end; and a second resilient plug initially disposed at the other end of the tubular body and slidable therethrough to eject the medicament through a canula which penetrates the first named plug; said second plug having spaced end walls the fore one of which is adapted to be deformed in the region of its axis by the hydrostatic pressure created within the package by said ejection.
  • a medicament dispensing package comprising, in combination, a tubular body; a plug sealing one end; and a second resilient plug initially disposed atthe other end of the tubular body and Slidablc therethrough to eject the medicament through a canula which penetrates the first named plug; said second plug having a closed hollcw interior and a relatively thin fore wall. which fleXes towards Asaid interior under the hydrostatic pressure created Within the package during the ejection.
  • a medicament dispensing package comprising, in combination, a tubular body; and a resilient hollow7 plug sealing an opening in the body and slidablc therethrough to contract the interior volume of the package; said plug having end walls of 4diftereut thicknesses, the thinner end Wall being exposed to the medicament and so made as lo be reidily liexcd by the hydrostatic pressure created during an injection, and automatically resuming its natural unfleXed state when said pressure'is relieved.
  • a medicament dispensing package comprising, in combination, a body; and a slidable plug for said body having a closed hollow ⁇ interior and constructed and arranged to transmit mechanical pressure at and near the periphery thereof and having one end face sufficiently flexible to be distended within said hollow interior by hydrostatic pressure within the package.
  • a hypodermic syringe embodying a cartridge and needle in communication therewith, said cartridge having a piston plug with a closed hollow interior, the fore wall of which plug is adapted to be flexed by hydrostatic pressure in the fluid-ejecting operation, for the purpose described.
  • a syringe cartridge having a piston plug composed of two sections, including a recessed or substantially cup-shaped section the recess oit which is closed by the other section, the loro wall of said plug adapted to be flexed by hydrostatic pressure in the ⁇ luid-ejecting operation, for the purpose described.
  • a syringe cartridge having a piston plug comprising a rear section to be engaged by a plunger and a substantially cupshaped fore section of resilient material arranged with its recess facing the rear section.
  • a syringe cartridge embodying a composite plug composed ot two recessed sections so positioned that the recesses thereof provide a closed hollow chamber the inner one ot said sections having an en wall adapted to be flexed by lhydrostatic pressure in the tluid-ejecting operation.
  • a syringe cartridge embodying a resilient plug composed of two recessed sections united so that the recesses provide a closed hollow chamber within the plug, one of said sections being of larger external diameter than the other, the smaller section having a relatively thin end wall adjacent said hollow chamber.
  • a syringe cartridge having a piston plug embodying an elastic closed hollow body adapted to be compressed in the fluidejecting operation and to expand toward the discharge end of the cartridge when the pressure is released, for the purpose set forth.
  • a syringe cartridge embodying a piston plug comprising an elastic stopper having a closed hollow interior, said stopper constructed to receive and transmit plunger thrust applied against its back end and adapted to undergo compression in the fluidejectns; operation in a manner such that; when the pressure is released the stopper will exert an expansion action toward the discharge end of the cartridge, for the pur- ROLAND C. REHM.

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  • Health & Medical Sciences (AREA)
  • Vascular Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)

Description

March 12, 1929. R, REHM v 1,704,924
SYR I NGE CARTRIDGE Filed sept.. 5, 192s Patented Mar. 12, 1929.
UNITE-D STATES PATENT OFFICE.
ROLAND C, REHM', 0F EVANSTON, ILLINOIS, ASSIGNOR TO COOK LABORATORIES, INC.,
I A CORPORATION 0F DELAWARE.
SYRINGE CARTRIDGE.
Application led September 5, 1925. Serial No. 54,644.
This invention relates to cartridges or medicament-dispensing packages for use as operative components of hypodermlc s inges. The object is to provide a cartri ge with an improved piston plug adapted upon release of the applied operating pressure to eXert an action counter to that which would tend to produce back-suction.
A cartridge embodying the invention 1n lo one practicable form is shown for illustration in the annexed drawings, in which:
Fig. 1 is a longitudinal section of a syringe containing said cartridge as an opera tive component thereof;
Fig. 2 is an enlarged view in longitudinal section of a fragment of the cartridge, showing the piston plug being forced forward by the syringe lunger; Fig. 3 is a etailed perspective view of 20 the plston plug on an enlarged scale.
The illustrative cartridge, comprising a glass tube 12 sealed by rubber plugs or stoppers 13 and 14, is shown in Fig. 1 in an instrument which in conjunction with the cartridge provides an operative syringe or injection-administering organization. Said instrument comprises a cartridge-holder 5 having removable heads 6 and 7. In the breech head 7 is a slidable plunger rod- 8 having an enlarged inner end 9 adapted to enter the glass cartridge tube and drive the stopper 14 forward for ejecting the liquid contents of the cartridge through the in'ecting needle attached to the fore end o the instrument. Communication between the cartridge and needle is established in this instance by penetration of the inwardly projecting end of the needle throughthe readily pierccable recessed rubber'stopper`13 in the fore cnd of the cartridge. By means of an intermediate needle enlargement 11, seated in the head (i, the needle is held in place. It will be understood that this particular organization is merely exemplary.
The rubber plug 14, which in this instance is a slidable piston plug as well as a sealing closure, is designed or constructed so that any distortion which the plug undergoes by plunger thrust during the fluid-ejecting operation will not cause a back-suction bywreflexing of the plug when the pressure on the hw cannot cause relative forward 2:1
syringe plunger is relaxed. In fact, upon vrelease of the applied pressure the plug will react in a manner to counteract or prevent sucking-back tendency. As shown, the saidl plug 14 has an interior closed cavity 15 and a relativel thin front Wfall 16 exposed to the liquid in t e cartridge. The back wall of the hollow plug and its annular wall around the cavity are relatively thick to provide a sufliciently firm plug to be compressed in the cartridge tube and which may be pushed forward by the plungerapplied against the back end of the plug. By reason of the cavity 15, it will be apparent that the thrust of the plunger against the tight fitted rubber rotrusion of the major Acentral portion o the front of the plug. Hence the opportunity for distortion by plunger thrust in a manner which would cause back-suction by reflexing,` is minimized. Moreover, in the fluidejecting operation, the fluid pressure in the cartridge acting against the resilient or flexible fore wall 16 will cause said wall to flex backward or bulge into the cavity, as indicated in Fig. 2; and when the applied pressure is released the reflexing of the wall in resuming its normal undistended position will be in a direction tending to continue the ejection' and thus have an effect contrary to a sucking-back tendency. IThe wall 16 may be sufficiently thin to be quite flexible and to lprovide a pressure sensitive diaphragm which will be distended as soon as any pressure' is applied on the liquid and will relax immediately after the pressure ceases.
While the described piston plug may be made in various ways, I contemplate making it by uniting two separate recessed or cupshaped sections as shown, their contacting ends being cemented or otherwise suitably joined. Preferably the front section is ofC originally smaller diameter than the other, 95 so that the compression of the plug when inserted in the cartridge tube will not bow or improperly affect thc wall 1G, and also because it is deemed preferable to have the rear plllugereugageable section in tighter 1m engagement with the glass tube than the fore section.
The described piston plug may be considered as oneembodying an elastic closed hollow body adapted to be compressed in the tluid-ejccting operation, as manifested by contraction oi" the cavity, and which upon release of the pressure will expand toward the discharge end otl the cartridge.
In view of a prior invention of Harvey S. Cook, described and claimed in his pending application Serial No. 71,319, filed November 25, 1925 as a division ot' an earlier application, which vembraces a cartridge having a rubber piston plug formed or conlstructed so that when the pressure is released the plug or a portion thereof exposed to the internal fluid pressure will reflex in a direction to counteract or prevent a sucking-back tendency, I make no claim herein such as tov cover said prior Cook invention.
Notice is also given that the particular syringe organization and cartridge therefor herein shown embody other vprior inventions ot said Harvey S. Cook, including a cartridge having the kind of pierceable fore plug or stopper herein shown, and an organization comprisingr such a cartridge with an instrument of substantially the construction herein shown; which prior Cook inventions are described and claimed by him in prior applications for patent now pending.
What I claim is:
1. A medicament dispensing package comprising, in combination, a tubular body; a plug scaling one end; and a second resilient plug initially disposed at the other end of the tubular body and slidable therethrough to eject the medicament through a canula which penetrates the first named plug; said second plug having spaced end walls the fore one of which is adapted to be deformed in the region of its axis by the hydrostatic pressure created within the package by said ejection.
2. A medicament dispensing package comprising, in combination, a tubular body; a plug sealing one end; and a second resilient plug initially disposed atthe other end of the tubular body and Slidablc therethrough to eject the medicament through a canula which penetrates the first named plug; said second plug having a closed hollcw interior and a relatively thin fore wall. which fleXes towards Asaid interior under the hydrostatic pressure created Within the package during the ejection.
3. A medicament dispensing package comprising, in combination, a tubular body; and a resilient hollow7 plug sealing an opening in the body and slidablc therethrough to contract the interior volume of the package; said plug having end walls of 4diftereut thicknesses, the thinner end Wall being exposed to the medicament and so made as lo be reidily liexcd by the hydrostatic pressure created during an injection, and automatically resuming its natural unfleXed state when said pressure'is relieved.
4. A medicament dispensing package comprising, in combination, a body; and a slidable plug for said body having a closed hollow` interior and constructed and arranged to transmit mechanical pressure at and near the periphery thereof and having one end face sufficiently flexible to be distended within said hollow interior by hydrostatic pressure within the package.
5. A hypodermic syringe embodying a cartridge and needle in communication therewith, said cartridge having a piston plug with a closed hollow interior, the fore wall of which plug is adapted to be flexed by hydrostatic pressure in the fluid-ejecting operation, for the purpose described.
6. A syringe cartridge embodying a piston plug with a closed hollow interior, the fore wall ol which plug is adapted to be flexed by hydrostatic pressure in the Huidejecting operation, for the purpose vdescribed.
7. A syringe cartridge embodying a closed hollow piston plug of resilient material having a relatively thick back wall and a relatively thin fore wall.
8. A syringe cartridge having a piston plug composed of two sections, including a recessed or substantially cup-shaped section the recess oit which is closed by the other section, the loro wall of said plug adapted to be flexed by hydrostatic pressure in the {luid-ejecting operation, for the purpose described.
9. A syringe cartridge having a piston plug comprising a rear section to be engaged by a plunger and a substantially cupshaped fore section of resilient material arranged with its recess facing the rear section.
10. A syringe cartridge embodying a composite plug composed ot two recessed sections so positioned that the recesses thereof provide a closed hollow chamber the inner one ot said sections having an en wall adapted to be flexed by lhydrostatic pressure in the tluid-ejecting operation.
11. A syringe cartridge embodying a resilient plug composed of two recessed sections united so that the recesses provide a closed hollow chamber within the plug, one of said sections being of larger external diameter than the other, the smaller section having a relatively thin end wall adjacent said hollow chamber.
12. A syringe cartridge having a piston plug embodying an elastic closed hollow body adapted to be compressed in the fluidejecting operation and to expand toward the discharge end of the cartridge when the pressure is released, for the purpose set forth.
13. A syringe cartridge embodying a piston plug comprising an elastic stopper having a closed hollow interior, said stopper constructed to receive and transmit plunger thrust applied against its back end and adapted to undergo compression in the fluidejectns; operation in a manner such that; when the pressure is released the stopper will exert an expansion action toward the discharge end of the cartridge, for the pur- ROLAND C. REHM.
I have signed my
US54644A 1925-09-05 1925-09-05 Syringe cartridge Expired - Lifetime US1704924A (en)

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Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2526365A (en) * 1949-03-07 1950-10-17 Jorgensen Niels Bjorn Hypodermic syringe
US2538391A (en) * 1948-01-10 1951-01-16 Arthur E Smith Syringe
US2561233A (en) * 1949-03-19 1951-07-17 Abbott Lab Hypodermic syringe
US2602447A (en) * 1947-12-20 1952-07-08 Kollsman Paul Device for hypodermic injection
US2622595A (en) * 1947-12-20 1952-12-23 Kollsman Paul Device for hypodermic injections
US3092108A (en) * 1954-04-09 1963-06-04 Friedman Benjamin Syringes and/or hypodermic needles, and cartridges therefor
US4240430A (en) * 1979-06-29 1980-12-23 The Kendall Company Syringe assembly
US11103644B2 (en) * 2012-06-01 2021-08-31 Novartis Ag Syringe

Cited By (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2602447A (en) * 1947-12-20 1952-07-08 Kollsman Paul Device for hypodermic injection
US2622595A (en) * 1947-12-20 1952-12-23 Kollsman Paul Device for hypodermic injections
US2538391A (en) * 1948-01-10 1951-01-16 Arthur E Smith Syringe
US2526365A (en) * 1949-03-07 1950-10-17 Jorgensen Niels Bjorn Hypodermic syringe
US2561233A (en) * 1949-03-19 1951-07-17 Abbott Lab Hypodermic syringe
US3092108A (en) * 1954-04-09 1963-06-04 Friedman Benjamin Syringes and/or hypodermic needles, and cartridges therefor
US4240430A (en) * 1979-06-29 1980-12-23 The Kendall Company Syringe assembly
US11103644B2 (en) * 2012-06-01 2021-08-31 Novartis Ag Syringe
US11110226B2 (en) 2012-06-01 2021-09-07 Novartis Ag Syringe
US11147925B2 (en) 2012-06-01 2021-10-19 Novartis Ag Syringe
US11179521B2 (en) 2012-06-01 2021-11-23 Novartis Ag Syringe
US11185635B2 (en) 2012-06-01 2021-11-30 Novartis Ag Syringe
US12048837B2 (en) 2012-06-01 2024-07-30 Novartis Ag Syringe

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