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UA99913C2 - Способ получения 6-{4-[3-((r)-2-метилпирролидин-1-ил)пропокси]фенил}-2н-пиридазин-3-она и его солей - Google Patents

Способ получения 6-{4-[3-((r)-2-метилпирролидин-1-ил)пропокси]фенил}-2н-пиридазин-3-она и его солей

Info

Publication number
UA99913C2
UA99913C2 UAA200912476A UAA200912476A UA99913C2 UA 99913 C2 UA99913 C2 UA 99913C2 UA A200912476 A UAA200912476 A UA A200912476A UA A200912476 A UAA200912476 A UA A200912476A UA 99913 C2 UA99913 C2 UA 99913C2
Authority
UA
Ukraine
Prior art keywords
methylpyrrolidine
pyridazin
propoxy
phenyl
salts
Prior art date
Application number
UAA200912476A
Other languages
English (en)
Ukrainian (uk)
Inventor
Майкл Кристи
Джозеф Дж. Петрейтис
Original Assignee
Сефалон, Инк.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Сефалон, Инк. filed Critical Сефалон, Инк.
Publication of UA99913C2 publication Critical patent/UA99913C2/ru

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/06—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with radicals, containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Catalysts (AREA)
  • Cosmetics (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Данное изобретение касается быстрого, безопасного, недорогого и крупномасштабного способа получения 6-{4-[3-((R)-2-метилпирролидин-1-ил)пропокси]фенил}-2Н-пиридазин-3-она и его солей.
UAA200912476A 2007-05-03 2008-05-02 Способ получения 6-{4-[3-((r)-2-метилпирролидин-1-ил)пропокси]фенил}-2н-пиридазин-3-она и его солей UA99913C2 (ru)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US92735607P 2007-05-03 2007-05-03

Publications (1)

Publication Number Publication Date
UA99913C2 true UA99913C2 (ru) 2012-10-25

Family

ID=39688886

Family Applications (1)

Application Number Title Priority Date Filing Date
UAA200912476A UA99913C2 (ru) 2007-05-03 2008-05-02 Способ получения 6-{4-[3-((r)-2-метилпирролидин-1-ил)пропокси]фенил}-2н-пиридазин-3-она и его солей

Country Status (14)

Country Link
EP (1) EP2152669A1 (ru)
JP (1) JP5698887B2 (ru)
KR (1) KR20100017565A (ru)
CN (1) CN101679237A (ru)
AU (1) AU2008248168B2 (ru)
BR (1) BRPI0810330A2 (ru)
CA (1) CA2686033A1 (ru)
EA (1) EA019031B1 (ru)
IL (1) IL201627A (ru)
MX (1) MX2009011787A (ru)
NZ (1) NZ580948A (ru)
UA (1) UA99913C2 (ru)
WO (1) WO2008137087A1 (ru)
ZA (1) ZA200907643B (ru)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT2069312E (pt) 2006-07-25 2013-01-24 Cephalon Inc Derivados de piridizinona
US8383657B2 (en) 2007-12-21 2013-02-26 Abbott Laboratories Thiazolylidine urea and amide derivatives and methods of use thereof
ES2479440T3 (es) * 2008-01-30 2014-07-24 Cephalon, Inc. Derivados de piridazina sustituidos que tienen actividad antagonista de histamina H3
ES2707123T3 (es) * 2014-12-23 2019-04-02 Cephalon Inc Métodos para la preparación de derivados 2, 4-diaminopirimidin bicíclicos fusionados

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3329974A1 (de) 1983-08-19 1985-02-28 Bayer Ag, 5090 Leverkusen Herstellung von hydrierten nitrilkautschuken
DE3433392A1 (de) 1984-09-12 1986-03-20 Bayer Ag, 5090 Leverkusen Hydrierung nitrilgruppenhaltiger ungesaettigter polymerer
FR2714849B1 (fr) 1994-01-13 1996-04-05 Inst Francais Du Petrole Procédé de préparation d'un catalyseur d'hydrogénation soluble en phase liquide organique.
DE4403479A1 (de) 1994-02-04 1995-08-10 Basf Ag Verfahren zur Herstellung von Hydroxylammoniumsalzen
WO2004024707A2 (en) * 2002-09-16 2004-03-25 Abbott Laboratories Process for preparing amine type substituted benzofurans
US7153889B2 (en) 2002-11-12 2006-12-26 Abbott Laboratories Bicyclic-substituted amines as histamine-3 receptor ligands
JP5055525B2 (ja) 2004-03-08 2012-10-24 独立行政法人科学技術振興機構 高分子担持金属クラスター組成物
US7145005B2 (en) 2004-05-12 2006-12-05 Abbott Laboratories 2-(6-{2-[(2R)-2-Methyl-1-pyrrolidin-1-yl]-ethyl}-2-naphthalen-2-yl)-2H-pyridazin-3-one salts and their preparation
WO2005117865A1 (en) 2004-06-02 2005-12-15 F. Hoffmann-La Roche Ag Naphthaline derivatives useful as histamine-3-receptor ligands
CA2588867A1 (en) 2004-12-01 2006-06-08 Banyu Pharmaceutical Co., Ltd. Substituted pyridone derivative
WO2006066197A1 (en) 2004-12-17 2006-06-22 Janssen Pharmaceutica, N.V. Tetrahydroisoquinoline compounds for treatment of cns disorders
CN101107231A (zh) 2005-01-21 2008-01-16 先灵公司 用作组胺h3拮抗剂的咪唑和苯并咪唑衍生物
EP1866293A1 (en) 2005-03-31 2007-12-19 UCB Pharma, S.A. Compounds comprising an oxazole or thiazole moiety, processes for making them, and their uses
GB0514812D0 (en) 2005-07-19 2005-08-24 Glaxo Group Ltd Compounds
CN101296902A (zh) 2005-10-27 2008-10-29 Ucb医药有限公司 包含内酰胺或内酰胺衍生部分的化合物、制备它们的方法和它们的用途
US7897634B2 (en) 2006-02-09 2011-03-01 Athersys, Inc. Pyrazoles for the treatment of obesity and other CNS disorders
WO2007099423A1 (en) 2006-03-02 2007-09-07 Pfizer Products Inc. 1-pyrrolidine indane derivatives as histamine-3 receptor antagonists
CA2643055A1 (en) 2006-03-13 2007-09-20 Pfizer Products Inc. Tetralines antagonists of the h-3 receptor
JP2009542673A (ja) 2006-06-29 2009-12-03 アリーナ ファーマシューティカルズ， インコーポレイテッド ヒスタミンｈ３−受容体関連障害の治療に有用なヒスタミンｈ３−受容体モジュレータ
PT2069312E (pt) 2006-07-25 2013-01-24 Cephalon Inc Derivados de piridizinona

Also Published As

Publication number Publication date
ZA200907643B (en) 2014-03-26
CN101679237A (zh) 2010-03-24
MX2009011787A (es) 2009-11-13
BRPI0810330A2 (pt) 2014-10-14
JP2010526142A (ja) 2010-07-29
IL201627A (en) 2014-06-30
EA019031B1 (ru) 2013-12-30
IL201627A0 (en) 2010-05-31
EP2152669A1 (en) 2010-02-17
NZ580948A (en) 2011-04-29
KR20100017565A (ko) 2010-02-16
JP5698887B2 (ja) 2015-04-08
AU2008248168A1 (en) 2008-11-13
WO2008137087A1 (en) 2008-11-13
EA200971019A1 (ru) 2010-04-30
AU2008248168B2 (en) 2013-03-21
CA2686033A1 (en) 2008-11-13

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