Nothing Special   »   [go: up one dir, main page]

UA96265C2 - Composition and method for inhibition of the jak pathway - Google Patents

Composition and method for inhibition of the jak pathway

Info

Publication number
UA96265C2
UA96265C2 UAA200714921A UAA200714921A UA96265C2 UA 96265 C2 UA96265 C2 UA 96265C2 UA A200714921 A UAA200714921 A UA A200714921A UA A200714921 A UAA200714921 A UA A200714921A UA 96265 C2 UA96265 C2 UA 96265C2
Authority
UA
Ukraine
Prior art keywords
inhibition
composition
jak pathway
jak
pathway
Prior art date
Application number
UAA200714921A
Other languages
Russian (ru)
Ukrainian (uk)
Inventor
Гуи Ли
Самбаиах Тота
Дейвид Керролл
Анкуш Аргейд
Кин Тсо
Арвиндер Срен
Джеффри Клоф
Хольгер Кеим
Сомасекхар БХАМИДИПАТИ
Ванесса Тейлор
Робин КУПЕР
Раджиндер Сингх
Брайан Вонг
Original Assignee
Райджел Фармасьютикалс, Инк.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Райджел Фармасьютикалс, Инк. filed Critical Райджел Фармасьютикалс, Инк.
Publication of UA96265C2 publication Critical patent/UA96265C2/en

Links

Landscapes

  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

The invention encompasses compounds having formula (I-V) and the compositions and methods using these compounds in the treatment of conditions in which modulation of the JAK pathway or inhibition of JAK kinases, particularly JAK3, may be therapeutically useful.
UAA200714921A 2005-06-08 2006-06-08 Composition and method for inhibition of the jak pathway UA96265C2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US68903205P 2005-06-08 2005-06-08

Publications (1)

Publication Number Publication Date
UA96265C2 true UA96265C2 (en) 2011-10-25

Family

ID=40014879

Family Applications (1)

Application Number Title Priority Date Filing Date
UAA200714921A UA96265C2 (en) 2005-06-08 2006-06-08 Composition and method for inhibition of the jak pathway

Country Status (3)

Country Link
CN (1) CN101282945A (en)
UA (1) UA96265C2 (en)
ZA (2) ZA200710206B (en)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8338439B2 (en) * 2008-06-27 2012-12-25 Celgene Avilomics Research, Inc. 2,4-disubstituted pyrimidines useful as kinase inhibitors
WO2010072155A1 (en) * 2008-12-26 2010-07-01 复旦大学 Pyrimidine derivative, preparation method and use thereof
WO2010083241A2 (en) * 2009-01-14 2010-07-22 Rigel Pharmaceuticals, Inc. 2,4-pyrimidinediamine compounds for treatment of inflammatory disorders
ES2880622T3 (en) * 2010-07-28 2021-11-25 Rigel Pharmaceuticals Inc Compositions and procedures for inhibition of the JAK pathway
CN103159749A (en) * 2011-12-13 2013-06-19 南京友杰医药科技有限公司 Synthesis method for antidepressant drug vilazodone
CA2927079C (en) * 2013-10-16 2017-05-23 Fujifilm Corporation Salt of nitrogen-containing heterocyclic compound or crystal thereof, pharmaceutical composition, and flt3 inhibitor
CN105924389A (en) * 2015-12-18 2016-09-07 重庆两江药物研发中心有限公司 Preparation method of regorafenib intermediate
CN110256465B (en) * 2019-07-13 2021-08-13 南方医科大学 2, 4-diaminopyrimidine containing dihydropyranothiazole and application thereof
CN117402178B (en) * 2023-12-15 2024-03-08 英矽智能科技(上海)有限公司 Pyrimidine compounds as JAK inhibitors and PHD inhibitors

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0004888D0 (en) * 2000-03-01 2000-04-19 Astrazeneca Uk Ltd Chemical compounds

Also Published As

Publication number Publication date
ZA200809949B (en) 2010-08-25
ZA200710206B (en) 2009-12-30
CN101282945A (en) 2008-10-08

Similar Documents

Publication Publication Date Title
WO2006133426A3 (en) Compositions and methods for inhibition of the jak pathway
WO2007098507A3 (en) Compositions and methods for inhibition of the jak pathway
WO2008049123A3 (en) 2,4-pyrimidinediamine derivatives as inhibitors of jak kinases for the treatment of autoimmune diseases
WO2008118823A3 (en) Compositions and methods for inhibition of the jak pathway
MX2011007750A (en) Compositions and methods for inhibition of the jak pathway.
UA96265C2 (en) Composition and method for inhibition of the jak pathway
PT1984357E (en) 2,4-pyrimidinediamine compounds for treating or preventing autoimmune diseases
MX2009006535A (en) Indol-4-yl-pyrimidinyl-2-yl-amine derivatives and use thereof as cyclin dependant kinase inhibitors.
MX2007008555A (en) Amino-imidazolones for the inhibition of ??-secretase.
WO2010075558A3 (en) Compositions and methods for inhibition of the jak pathway
MX2020009397A (en) Compositions and methods for inhibition of the jak pathway.
WO2007011962A3 (en) Treatment of cancer
IL196543A (en) Pyridazinone derivatives and pharmaceutical compositions comprising them for use in the treatment of disorders
WO2006024018A3 (en) Compositions for treating nociceptive pain
WO2006073457A3 (en) Bioactive compounds and methods of uses thereof
TW200736229A (en) Substituted 1H-benzimidazole-4-carboxamides are potent PARP inhibitors
TW200604192A (en) Compounds and methods for inhibiting mitotic progression
WO2006123113A3 (en) Pyrazolylaminopyrimidine derivatives useful as tyrosine kinase inhibitors
PT2332940E (en) Azaindoles useful as inhibitors of jak and other protein kinases
WO2007095124A3 (en) Benzazole derivatives, compositions, and methods of use as aurora kinase inhibitors
UA101478C2 (en) Compounds useful as inhibitors of raf protein kinase
WO2009032668A3 (en) 2 -biphenylamino-4 -aminopyrimidine derivatives as kinase inhibitors
ZA200710379B (en) Pyrrolopyridines useful as inhibitors of protein kinase
WO2006106326A8 (en) Substituted heterocycles and their use as chk1, pdk1 and pak inhibitors
MX2009005881A (en) Non-nucleoside reverse transcriptase inhibitors.