Nothing Special   »   [go: up one dir, main page]

UA81387C2 - Pharmaceutical combination of ethinylestradiol and drospirenone for use as a contraceptive - Google Patents

Pharmaceutical combination of ethinylestradiol and drospirenone for use as a contraceptive

Info

Publication number
UA81387C2
UA81387C2 UA2002032519A UA2002032519A UA81387C2 UA 81387 C2 UA81387 C2 UA 81387C2 UA 2002032519 A UA2002032519 A UA 2002032519A UA 2002032519 A UA2002032519 A UA 2002032519A UA 81387 C2 UA81387 C2 UA 81387C2
Authority
UA
Ukraine
Prior art keywords
ethinylestradiol
daily dosage
drospirenone
active agent
composition
Prior art date
Application number
UA2002032519A
Inventor
Wolfgang Heil
Ralph Lipp
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26153358&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=UA81387(C2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Schering Ag filed Critical Schering Ag
Priority claimed from PCT/IB2000/001213 external-priority patent/WO2001015701A1/en
Publication of UA81387C2 publication Critical patent/UA81387C2/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • A61K31/585—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin containing lactone rings, e.g. oxandrolone, bufalin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)

Abstract

A pharmaceutical composition comprises, as a first active agent, 6 , 7 , 15 , l6 -dimethylene3-oxo-17 -pregn-4-ene-21,17-carbolactone (drospirenone) in an amount corresponding to a daily dosage, on administration of the composition, of from about 2 mg to about 4 mg, and, as a second active agent, 17 -ethinylestradiol (ethinylestradiol) in an amount corresponding to a daily dosage of from about 0.01 mg to about 0.05 mg, together with one or more pharmaceutically acceptable carriers or excipients. In a specific embodiment, the composition consists of a number of separately packaged and individually removable daily dosage units placed in a packaging unit and intended for oral administration for a period of at least 21 consecutive days, wherein said daily dosage units comprise the combination of drospirenone and ethinylestradiol. The composition may further comprise 7 or less daily dosage units containing no active agent or containing ethinylestradiol alone.
UA2002032519A 1999-08-31 2000-08-31 Pharmaceutical combination of ethinylestradiol and drospirenone for use as a contraceptive UA81387C2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US24095399P 1999-08-31 1999-08-31
EP99202826 1999-08-31
PCT/IB2000/001213 WO2001015701A1 (en) 1999-08-31 2000-08-31 Pharmaceutical combination of ethinylestradiol and drospirenone for use as a contraceptive

Publications (1)

Publication Number Publication Date
UA81387C2 true UA81387C2 (en) 2008-01-10

Family

ID=26153358

Family Applications (1)

Application Number Title Priority Date Filing Date
UA2002032519A UA81387C2 (en) 1999-08-31 2000-08-31 Pharmaceutical combination of ethinylestradiol and drospirenone for use as a contraceptive

Country Status (11)

Country Link
CN (1) CN1223350C (en)
BG (2) BG109749A (en)
CA (1) CA2382426C (en)
EE (1) EE05317B1 (en)
HR (1) HRP20020258B1 (en)
IL (2) IL197396A (en)
MX (1) MXPA02002043A (en)
NO (3) NO327588B3 (en)
RU (4) RU2269342C2 (en)
SK (1) SK287634B6 (en)
UA (1) UA81387C2 (en)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1625849A1 (en) * 2004-08-09 2006-02-15 Liconsa, Liberacion Controlada de Sustancias Activas, S.A. Pharmaceutical composition comprising drospirenone and ethynylestradiol
CN101489563A (en) * 2006-07-06 2009-07-22 拜耳先灵医药股份有限公司 Pharmaceutical preparations for contraception and for preventing the risk of congenital malformations
US9301920B2 (en) 2012-06-18 2016-04-05 Therapeuticsmd, Inc. Natural combination hormone replacement formulations and therapies
US8633178B2 (en) 2011-11-23 2014-01-21 Therapeuticsmd, Inc. Natural combination hormone replacement formulations and therapies
RU2618471C2 (en) * 2012-12-03 2017-05-03 Закрытое Акционерное Общество "Вертекс" Oral pharmaceutical composition of diuretics and ace inhibitor in micronized form, drug and its application
US11266661B2 (en) 2012-12-21 2022-03-08 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
MX2016014281A (en) 2014-05-22 2017-02-22 Therapeuticsmd Inc Natural combination hormone replacement formulations and therapies.
CN108606963B (en) * 2017-12-27 2021-05-18 上海长海医院 Compound contraceptive patch containing drospirenone and estrogen, preparation method and application
CN111529482A (en) * 2020-05-20 2020-08-14 祝培 Testosterone undecanoate sustained-release implant and application thereof

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2652761C2 (en) * 1976-11-16 1985-11-21 Schering AG, 1000 Berlin und 4709 Bergkamen 15,16-methylene-spirolactones, processes for their preparation and pharmaceuticals containing them
DE4344462C2 (en) * 1993-12-22 1996-02-01 Schering Ag Composition for contraception
DE4411585A1 (en) * 1994-03-30 1995-10-05 Schering Ag Combined pharmaceutical preparation for hormonal contraception
PT956024E (en) * 1996-07-26 2004-10-29 Wyeth Corp MONOPHASIC ORAL CONTRACEPTIVE METHOD AND COVER ("KIT") COMPREHENDING A COMBINATION OF A PROGESTINE AND ESTROGEN

Also Published As

Publication number Publication date
EE200900049A (en) 2009-10-15
NO20091809L (en) 2002-04-26
CN1407895A (en) 2003-04-02
IL200482A0 (en) 2011-07-31
RU2269342C2 (en) 2006-02-10
SK2572002A3 (en) 2002-11-06
BG106533A (en) 2002-10-31
RU2010114825A (en) 2011-10-20
IL197396A (en) 2010-04-29
RU2396082C2 (en) 2010-08-10
RU2005131868A (en) 2007-04-20
MXPA02002043A (en) 2003-08-20
NO327588B3 (en) 2011-05-16
RU2449796C2 (en) 2006-02-10
BG65204B1 (en) 2007-07-31
NO2010004I1 (en) 2010-03-22
NO327588B1 (en) 2009-08-31
HRP20020258B1 (en) 2007-05-31
HRP20020258A2 (en) 2005-02-28
CA2382426A1 (en) 2001-03-08
RU2482853C2 (en) 2013-05-27
CN1223350C (en) 2005-10-19
SK287634B6 (en) 2011-04-05
RU2269342C9 (en) 2007-10-27
RU2449796C9 (en) 2007-10-27
NO20083854L (en) 2002-04-26
BG109749A (en) 2008-06-30
CA2382426C (en) 2006-02-28
EE05317B1 (en) 2010-08-16

Similar Documents

Publication Publication Date Title
YU14502A (en) Pharmaceutical combination of ethinylestradiol and drospirenone for use as a contraceptive
BG66095B1 (en) Pregelatinized starch in a controlled release preparation
UA41401C2 (en) Pharmaceutical combined contraceptive agent
NO327588B1 (en) Pharmaceutical composition and composition comprising ethinylostradiol and drospirenone for use as a contraceptive
TW355683B (en) Composition containing micronized nebivolol
YU33099A (en) Pharmaceutical composition
AP2003002763A0 (en) Controlled release formulations for oral administration
WO2002011694A3 (en) Compositions and dosage forms for application in the oral cavity in the treatment of mykoses
CA2347750A1 (en) Pharmaceutical composition containing decursin
TW200638951A (en) Solid oral pharmaceutical form for contraception
HRP20080394T3 (en) Peroral solid dosage form for contraception comprising dienogest and ethinylestradiol
HRP20090256T1 (en) Use of estradiolvalerate and dienogest for oral treatment of dysfunctional uterine bleeding in a contraceptive method
JO2213B1 (en) A pharmaceutical composition for use as a contraceptive
EA200701091A1 (en) OPTICAL PHARMACEUTICALS
CA2248841A1 (en) Sequential oestrogen/progesterone antagonist combination for hormone replacement therapy
ECSP003721A (en) A PHARMACEUTICAL COMPOSITION TO BE USED AS AN CONTRACEPTIVE
EP2305267A3 (en) Pharmaceutical combination of ethinylestradiol and drospirenone for use as a contraceptive
TH54054B (en) Pharmaceutical mixtures for use as birth control pills
HRP20020666B1 (en) Drospirenone for hormone replacement therapy