TWI547695B - Analysis device and detecting module - Google Patents

Description

Analysis device and detection module

The invention relates to an analysis device and a detection module, and in particular to a liquid analysis device and a detection module thereof.

In recent years, miniaturized biochemical detection modules have been actively developed, and many miniaturized detection modules have also been applied to various analysis devices. The benefits of miniaturization on biochemical detection modules include the advantages of fast analysis, accurate quantification, low sample requirements, and space saving. As a result, many detection modules are gradually becoming smaller, even integrating detection wafers (such as biological Wafer).

In miniaturized biochemistry, the process of reacting or separating a portion of the sample liquid through the mixing of the reagent liquid can be performed on a miniaturized detection module equipped with a biochip, such as a test cartridge equipped with a biochip. . The sample liquid and the reagent liquid can perform the above-mentioned series of biochemical reactions on the miniaturization detecting module to cause the biochip to generate a telecommunication signal, and receive the electric signal by the signal unit of the analyzing device, according to the electric signal analysis The biological properties of the sample liquid are obtained. However, the injection unit that injects the reagent liquid into the detection module and the signal unit for transmitting the electrical signal are usually disposed on different devices, which complicates the operation of the biochemical analysis.

The invention provides an analysis device which has a liquid injection function and an electric signal transmission function, and has a relatively simple operation mode.

The present invention provides a detection module that can be used in an analysis device to detect sample liquid.

The analysis device of the present invention includes a detection module and a main module. The detecting module includes a first body, a first electrical connector and a detecting wafer. The first body has an injection opening, and a sample liquid is adapted to be disposed on the first body. The first electrical connector is disposed on the first body and located on a side of the injection opening. The detecting wafer is disposed in the first body and electrically connected to the first electrical connector. The detection module is adapted to be assembled to the main module. The main module includes a second body, an injection component, and a second electrical connector. The injection element is disposed on the second body. The second electrical connector is disposed on the second body and located on one side of the injection element. The detecting module is adapted to be connected to the main module with the injection opening corresponding to the injection component and the first electrical connector corresponding to the second electrical connector, wherein the injection component injects a reagent liquid into the first body through the injection opening, so that The sample liquid and the reagent liquid are mixed with each other in the first body. The detecting wafer analyzes the mixed reagent liquid and the sample liquid to generate a signal, and the electrical signal is transmitted to the main module through the first electrical connector and the second electrical connector.

The detection module of the present invention includes a first body, a first electrical connector, and a detection wafer. The first body has an injection opening, wherein a sample liquid is adapted to be disposed on the first body, and an injection element is adapted to pass a reagent liquid through the injection opening The first body is injected to mix the sample liquid and the reagent liquid with each other in the first body. The first electrical connector is disposed on the first body and located on a side of the injection opening. The detecting wafer is disposed in the first body and electrically connected to the first electrical connector. The test wafer analyzes the mixed reagent liquid and the sample liquid to generate an electrical signal. The electrical signal is transmitted to an analysis device via the first electrical connector.

Based on the above, in the detecting module of the present invention, the reagent liquid is injected into the first body through the injection opening, and is mixed with the sample liquid disposed in the first body, and the reagent liquid and the sample liquid after the wafer analysis and mixing are detected. To generate a signal. As such, in the analyzing device of the present invention, the detecting module is connected to the main module with the injection opening corresponding to the injection element and the first electrical connector corresponding to the second electrical connector. The main module injects the reagent liquid into the first body of the detecting module through the injection opening through the injection component, and detects the electric signal generated by the mixed reagent liquid and the sample liquid by the wafer analysis by the first electrical connector and the second The electrical connector is passed to the main module. Accordingly, the detection module of the present invention can be applied to an analysis device for detecting a sample liquid, and the analysis device has a liquid injection function and an electric signal transmission function, and has a relatively simple operation mode.

The above described features and advantages of the invention will be apparent from the following description.

100‧‧‧Analytical device

110, 110a‧‧‧ test module

112‧‧‧First Ontology

112a, 112b‧‧‧ injection opening

112c, 117a, 134‧‧‧ channels

114‧‧‧First electrical connector

Port 114a‧‧‧

116‧‧‧Detection wafer

117, 217‧‧‧ Seals

118a‧‧‧ accommodating grooves

118b‧‧‧Mixed groove

118c‧‧‧ waste liquid groove

119a‧‧‧First runner

119b‧‧‧Connecting the runner

119c‧‧‧Second runner

119d‧‧‧ third runner

120‧‧‧Main module

122‧‧‧Second ontology

124, 128‧‧‧Injection components

124a, 128a‧‧‧Fixed Department

124b, 128b‧‧‧ Insertion

126‧‧‧Second electrical connector

126a‧‧‧terminal

130‧‧‧Liquid collector

132, 217a‧‧‧through hole

R‧‧‧Measurement area

BRIEF DESCRIPTION OF THE DRAWINGS Fig. 1 is a perspective view of an analysis apparatus according to an embodiment of the present invention.

Figure 2 is a plan view of the analysis device of Figure 1 after assembly.

Figure 3 is a cross-sectional view of the analyzing device of Figure 2 taken along line A-A'.

Figure 4 is a cross-sectional view showing an analysis apparatus according to another embodiment of the present invention.

FIG. 5 is a top plan view of the detection module of FIG. 2. FIG.

BRIEF DESCRIPTION OF THE DRAWINGS Fig. 1 is a perspective view of an analysis apparatus according to an embodiment of the present invention. Figure 2 is a plan view of the analysis device of Figure 1 after assembly. Referring to FIG. 1 and FIG. 2 , in the embodiment, the analysis device 100 includes a detection module 110 and a main module 120 . The detection module 110 includes a first body 112, a first electrical connector 114, and a detection wafer 116. The first body 112 has an injection opening 112a, and the sample liquid not shown is adapted to be disposed on the first body 112. The first electrical connector 114 is disposed on the first body 112 and located on a side of the injection opening 112a. The detecting wafer 116 is disposed in the first body 112 and electrically connected to the first electrical connector 114. Furthermore, the detection module 110 is adapted to be assembled to the main module 120. The main module 120 includes a second body 122, an injection element 124, and a second electrical connector 126. The injection element 124 is disposed on the second body 122. The second electrical connector 126 is disposed on the second body 122 and is located on one side of the injection component 124. As such, the detection module 110 is adapted to be coupled to the main module 120 with the injection opening 112a corresponding to the injection element 124 and the first electrical connector 114 corresponding to the second electrical connector 126, wherein the injection element 124 will be a reagent not shown The liquid is injected into the first body 112 through the injection opening 112a to mix the sample liquid and the reagent liquid with each other within the first body 112. The detecting wafer 116 analyzes the mixed reagent liquid and the sample liquid to generate an electrical signal. The electrical signal is transmitted to the main module 120 by the first electrical connector 114 and the second electrical connector 126. Accordingly, the detection module 110 of the present embodiment can be applied to the analysis device 100 to detect the sample liquid, and the analysis device 100 has the liquid injection function and the electrical signal transmission function, and has a relatively simple operation mode.

Specifically, in the present embodiment, the detection module 110 is used to carry a sample liquid not shown, and the main module 120 is adapted to provide a reagent liquid for mixing with the sample liquid. After the sample liquid and the reagent liquid generate a series of mixing, separation and the like in the first body 112 of the detecting module 110, the detecting wafer 116 analyzes the mixed reagent liquid and the sample liquid and generates an electric signal according to the electric signal. The first electrical connector 114 and the second electrical connector 126 are transmitted to the main module 120. In this manner, the main module 120 can further carry the relevant analysis software to analyze the biological characteristics of the sample liquid and the reagent liquid according to the electrical signal. Further, in the present embodiment, the sample liquid is, for example, blood, and the reagent liquid is, for example, Phosphate buffered saline (PBS). Thereby, the detecting wafer 116 of the present embodiment may be a bio wafer, but the invention does not limit the types of the sample liquid, the reagent liquid and the detecting wafer 116. Depending on the type of sample liquid and the item to be analyzed, the type of reagent liquid can be adjusted accordingly. After the reagent liquid and the sample liquid react in the first body 112 of the detecting module 110, the biochip which is the detecting wafer 116 analyzes the mixed reagent liquid and the sample liquid and generates an electric signal, and the electric signal corresponds to The biological properties of the reagent liquid and the sample liquid after the reaction. Accordingly, after the electrical signal is transmitted to the main module 120 through the first electrical connector 114 and the second electrical connector 126, the main module 120 can analyze the biological characteristics of the sample liquid according to the electrical signal.

Therefore, in the embodiment, since the main module 120 provides the reagent liquid for reacting with the sample liquid, the main module 120 is stored in advance by the injection element 124 protruding from the second body 122. The reagent liquid in the second body 122 is injected into the first body 112 of the detection module 110 via the injection opening 112a of the first body 112. In addition, the first body 112 of the detecting module 110 of the embodiment has a micro flow channel structure (as described later). After the main module 120 injects the reagent liquid into the first body 112 to merge the reagent liquid with the sample liquid disposed in the first body 112, the reagent liquid and the sample liquid pass through the microchannel structure in the first body 112. Flowing and mixing with each other. The mixed reagent liquid and the sample liquid flow through the detecting wafer 116, so that the detecting wafer 116 analyzes the mixed reagent liquid and the sample liquid to generate a corresponding electrical signal. Moreover, in this embodiment, the first electrical connector 114 and the second electrical connector 126 can be connected to each other, wherein the first electrical connector 114 is, for example, a receptacle electrical connector, and the second electrical connector The 126 is, for example, a plug connector, but the present invention does not limit the types of the first electrical connector 114 and the second electrical connector 126. As such, the electrical signals generated by the test wafer 116 can be transmitted to the main module 120 through the first electrical connector 114 and the second electrical connector 126.

In addition, in the embodiment, the detection module 110 further includes another injection opening 112b, and the main module 120 further includes another injection component 128. The injection openings 112a and 112b are located on the first body 112 and are respectively located on opposite sides of the first electrical connector 114. Similarly, the injection elements 124 and 128 are disposed on the second body 122 and are located on opposite sides of the second electrical connector 126, respectively. As such, the injection element 128 is adapted to be correspondingly inserted into the injection opening 112b. Sample liquid and reagent liquid flow after mixing After detecting the wafer 116 and causing the detecting wafer 116 to generate an electrical signal, the injecting component 128 can inject a cleaning liquid (not shown) into the first body 112 for cleaning impurities on the detecting wafer 116 to improve the accuracy of the detection. It can be seen that the present invention does not limit the number and position of the injection element and the injection opening, which can be adjusted as needed.

Based on the above, in the analysis device 100, when the detection module 110 is assembled with the main module 120, the injection elements 124 and 128 are correspondingly inserted into the injection openings 112a and 112b to inject the reagent liquid and the cleaning liquid into the first body 112, At the same time, the plurality of terminals 126a of the second electrical connector 126 are correspondingly inserted into the plurality of ports 114a of the first electrical connector 114 for transmitting the electrical signals generated by the detecting wafer 116. Therefore, in this embodiment, the liquid injection function and the electrical signal transmission function corresponding to the detection module 110 are integrated into the single main module 120. Through the above assembly operation, the analysis device 100 of the present embodiment can perform the liquid injection and electric signal transmission functions. In other words, with the above configuration, the operation mode of the analysis device 100 can be simplified. Accordingly, the analysis device 100 of the present embodiment has a liquid injection function and an electric signal transmission function, and has a relatively simple operation mode.

Figure 3 is a cross-sectional view of the analyzing device of Figure 2 taken along line A-A'. Referring to FIG. 1 to FIG. 3, in the embodiment, the injection element 124 of the main module 120 includes a fixing portion 124a and an insertion portion 124b. The injection member 124 is fixed to the second body 122 with a fixing portion 124a and is adapted to be inserted into the injection opening 112a with the insertion portion 124b. In other words, the insertion portion 124b of the injection member 124 extends outward from the fixing portion 124a fixed to the second body 122 to assume a pin shape, and is adapted to be inserted into the injection opening 112a. However, the invention does not limit the shape of the injection element 124, which can be adjusted as needed. In addition, in the embodiment, the detecting module 110 further includes a sealing member 117. The sealing member 117 is disposed in the first body 112 and corresponds to the injection opening 112a to prevent the reagent liquid injected into the first body 112 through the injection element 124 from flowing out from the injection opening 112a. Specifically, the sealing member 117 is, for example, rubber or other suitable material, and has elasticity and water repellency, but the invention is not limited thereto. The seal 117 is disposed in the injection opening 112a and has a passage 117a, and the passage 117a penetrates the seal 117 and communicates to the injection opening 112a. As such, the injection element 124 is adapted to be inserted into the first body 112 from the injection opening 112a and penetrate the channel 117a such that the reagent liquid is injected into the first body 112 of the detection module 110 through the injection opening 112a and the channel 117a. Further, the diameter of the passage 117a of the seal member 117 is preferably slightly smaller than the diameter of the insertion portion 124b of the injection member 124. When the injection member 124 is inserted into the first body 112 from the injection opening 112a with the insertion portion 124b, the insertion portion 124b penetrates the passage 117a by pressing the inner side of the passage 117a, and the injection member 124 penetrates the passage 117a with the insertion portion 124b. A tight fit state is formed with the seal 117. Thus, by the blocking of the sealing member 117, the reagent liquid injected into the first body 112 through the injection member 124 can be prevented from flowing out from the injection opening 112a. Similarly, the injecting member 128 includes a fixing portion 128a and an insertion portion 128b. The injecting member 128 is fixed to the second body 122 by the fixing portion 128a and is adapted to be inserted into the injection opening 112b by the insertion portion 128b, and the injection opening 112b may be configured with The aforementioned sealing member 117 will not be further described herein.

Figure 4 is a cross-sectional view showing an analysis apparatus according to another embodiment of the present invention. Referring to FIG. 4, in the embodiment, the detecting module 110a has a similar structure and use as the detecting module 110, and the main difference is that the detecting module 110a is sealed. The piece 217 is different from the seal 117 of the detection module 110. Specifically, in the present embodiment, the sealing member 217 is disposed in the first body 112 and corresponds to the injection opening 112a to prevent the reagent liquid injected into the first body 112 through the injection element 124 from flowing out from the injection opening 112a. Wherein, the first body 112 of the embodiment has a channel 112c, and the channel 112c is connected to the injection opening 112a. Further, the seal 217 is disposed in the passage 112c of the first body 112 and has a through hole 217a, and the through hole 217a penetrates the seal 217 and communicates to the passage 112c. As such, the injection element 124 is adapted to be inserted into the first body 112 from the injection opening 112a and through the through hole 217a to correspond to the channel 112c, so that the reagent liquid is injected into the first body 112 of the detection module 110a through the injection opening 112a and the channel 112c. More specifically, the thickness of the seal 217 is smaller than the length of the passage 112c, and the diameter of the through hole 217a of the seal 217 is much smaller than the diameter of the insertion portion 124b of the injection member 124. As such, when the injection member 124 is inserted into the first body 112 from the injection opening 112a by the insertion portion 124b, since the thickness of the sealing member 217 is thin, the insertion portion 124b can pass through the through hole 217a by pressing the through hole 217a, and The insertion portion 124b corresponds to the passage 112c after passing through the through hole 217a. Thus, by the blocking of the sealing member 217, the reagent liquid injected into the first body 112 through the injection member 124 can be prevented from flowing out from the injection opening 112a. Similarly, the injection opening 112b may also be provided with the aforementioned sealing member 217, which will not be further described herein. As can be seen, the present invention does not limit the embodiment of the seal, which can be adjusted as needed.

FIG. 5 is a top plan view of the detection module of FIG. 2. FIG. Referring to FIG. 1 , FIG. 2 and FIG. 5 , in the embodiment, the detecting module 110 is used for carrying a sample liquid not shown, and is used for mixing and separating the reagent liquid not shown and the sample liquid. Equal path The detection wafer 116 is further configured to generate an electrical signal and provide an electrical signal to the main module 120 by analyzing the mixed reagent liquid and the sample liquid. The first body 112 of the detecting module 110 has the aforementioned micro-channel structure for flowing the reagent liquid and the sample liquid through the micro-channel structure in the first body 112 to mix and react with each other, and to mix The reacted reagent liquid and the sample liquid flow through the test wafer 116 to cause the test wafer 116 to generate corresponding electrical signals accordingly. One embodiment of the microchannel structure is provided below, but the invention is not limited thereto.

Specifically, in the embodiment, the detecting module 110 includes a receiving groove 118a, a first flow path 119a, a connecting flow path 119b, a mixing groove 118b, and a second flow path 119c. The accommodating recess 118a is disposed on the first body 112, and the sample liquid is adapted to be disposed in the accommodating recess 118a. The first flow path 119a is disposed in the first body 112 and communicates with the injection opening 112a and the accommodating recess 118a in which the sample liquid is disposed. The mixing groove 118b is disposed in the first body 112 and communicates through the connecting flow path 119b to the receiving groove 118a and the second flow path 119c where the sample liquid is disposed. The second flow path 119c is disposed in the first body 112 and communicates with the accommodating recess 118a in which the sample liquid is disposed and the measurement area R in which the detecting wafer 116 is disposed. As such, the reagent liquid is injected into the first body 112 through the injection opening 112a by the injection element 124 (shown in FIGS. 1 and 2), wherein the reagent liquid flows from the injection opening 112a into the accommodating recess 118a via the first flow path 119a, and After the sample liquid is contained in the accommodating recess 118a, it flows into the mixing groove 118b via the connecting flow path 119b to be mixed with the sample liquid in the mixing groove 118b. The reagent liquid and the sample liquid are mixed with each other in the mixing groove 118b and reacted to flow to the measurement region R via the second flow path 119c, and the detection wafer disposed in the measurement region R 116 analyzes the mixed sample liquid and the reagent liquid to generate an electrical signal. The micro-channel structure such as the accommodating recess 118a, the first flow channel 119a, the connecting channel 119b, the mixing groove 118b, and the second channel 119c are disposed in the first body 112, so the first body of the embodiment 112 can be made by two pieces of unillustrated splint, and the micro-channel structure is a groove or a ditch disposed on each of the plates, and is located between the plates after the plates are joined to each other. Thereby, in Fig. 5, the above-described microchannel structure between the splints is shown by a broken line. The microchannel structures are in communication with each other to form a continuous flow path within the first body 112 (between the splints), and the reagent liquid and the sample liquid flow in the microchannel structure in the first body 112. Mix with each other and produce a reaction.

In addition, in the embodiment, the analyzing device 100 further includes a liquid collector 130 disposed on the first body 112 of the detecting module 110 and located in the receiving recess 118a. The liquid collector 130 is adapted to collect the sample liquid and is assembled in the accommodating recess 118a, and the reagent liquid is adapted to flow from the first flow path 119a through the liquid collector 130 located in the accommodating recess 118a. The liquid is introduced into the mixing groove 118b via the connecting flow path 119b to be mixed with the sample liquid. Further, the liquid collector 130 of the present embodiment has the through holes 132 and the channels 134 that communicate with each other. After the liquid collector 130 collects the sample liquid and assembles it in the accommodating recess 118a, the passage 134 of the liquid collector 130 communicates with the first flow passage 119a, and the through hole 132 communicates with the connection flow passage 119b and the mixing recess 118b. Thus, the first flow path 119a, the passage 134, the through hole 132, the connecting flow path 119b and the mixing groove 118b constitute a continuous flow path, and the reagent liquid and the sample liquid are disposed at different points on the flow path, such as the reagent liquid. The injection opening 112a is the starting position, and the sample liquid is the liquid collector 130 The through hole 132 is a starting position. Thereby, the reagent liquid flows into the passage 134 of the liquid collector 130 from the first flow path 119a, and flows into the mixing groove 118b via the connecting flow path 119b after the sample liquid is carried in the through hole 132. However, the liquid collector 130 is only one of the embodiments of the present invention for arranging the sample liquid, and the present invention is not limited thereto. For example, the sample liquid may also be directly dropped into the accommodating recess 118a, or may be disposed in the accommodating recess 118a after being loaded by other containers. It can be seen from the above that the present invention does not limit the manner in which the sample liquid is disposed in the first body, which can be adjusted according to requirements.

Furthermore, in the embodiment, the waste body groove 118c can be disposed in the first body 112 of the detecting module 110 according to requirements. The waste liquid groove 118c is connected to the end of the second flow path 119c. After the partial component is separated from the mixed liquid obtained by mixing the reagent liquid and the sample liquid and flows to the measurement zone R in which the detection wafer 116 is disposed, the mixed liquid after use (the mixed liquid which has detected the electric wave generated by the wafer 116) It can be flowed to the waste liquid groove 118c through the second flow path 119c, that is, the used mixed liquid is collected by the waste liquid groove 118c. In other words, after the mixed liquid obtained by mixing the reagent liquid and the sample liquid flows through the measurement region R through the second flow path 119c to cause the detection wafer 116 disposed in the measurement region R to generate an electric signal, the mixed liquid is passed through the second The flow path 119 flows into and concentrates to the waste liquid groove 118c. However, the present invention does not limit the setting of the waste liquid groove 118c, which can be adjusted as needed. In addition, since the analysis device of the present embodiment can inject the cleaning liquid into the first body 112 by the injection component 128 (shown in FIG. 1 and FIG. 2 ), the detection module 110 of the embodiment further includes the third flow channel. 119d, which communicates with the injection opening 112b and the second flow path 119c, and is located between the measurement area R and the mixing groove 118b. As such, when the injection element 128 injects the cleaning fluid into the first body 112 At this time, the cleaning liquid flows into the second flow path 119c through the third flow path 119d, and flows through the measurement area R. As such, the cleaning solution can be used to clean the impurities on the inspection wafer 116 to improve the accuracy of the detection. Thereafter, the cleaning liquid with the residual liquid can flow into the waste liquid groove 118c via the second flow path 119c. The above described microchannel structure is merely illustrative of one embodiment of the invention and is not intended to limit the invention.

Referring to FIG. 1 , FIG. 2 and FIG. 5 again, in the embodiment, the detection module 110 is configured with the micro flow channel structure in the first body 112 according to requirements, so that the injection component 124 from the main module 120 is configured. The reagent liquid injected into the first body 112 of the detection module 110 may be mixed with the sample liquid in the first body 112 and reacted. Thereafter, the detecting wafer 116 analyzes the mixed reagent liquid and the sample liquid to generate an electrical signal, and transmits the electrical signal to the main module 120 through the first electrical connector 114 and the second electrical connector 126. It can be seen that the detection module 110 of the present embodiment can be applied to the analysis device 100 to detect the sample liquid, and the required liquid injection function and the electric signal transmission function are integrated in the main module 120. In this manner, the analysis device 100 can perform the above-described series of steps after assembling the detection module 110 and the main module 120. Therefore, the above design can simplify the operation mode of the analysis device. Accordingly, the detection module 110 of the present embodiment can be applied to the analysis device 100 to detect the sample liquid, and the analysis device 100 has the liquid injection function and the electrical signal transmission function, and has a relatively simple operation mode.

In summary, in the detecting module of the present invention, the reagent liquid is injected into the first body through the injection opening, and is mixed with the sample liquid disposed in the first body, and the reagent liquid and the test after the wafer analysis and mixing are detected. The liquid is used to generate a signal. Such as Therefore, in the analyzing device of the present invention, the detecting module is connected to the main module with the injection opening corresponding to the injection element and the first electrical connector corresponding to the second electrical connector. The main module injects a reagent liquid into the first body of the detecting module through the injection opening through the injection component, wherein the detecting module further comprises a sealing member disposed in the first body and corresponding to the injection opening, which can be used to avoid The reagent liquid injected into the first body by the injection element flows out from the injection opening. Detecting the wafer The electrical signal generated by the mixed reagent liquid and the sample liquid is transmitted to the main module through the first electrical connector and the second electrical connector. That is, the present invention integrates the liquid injection function and the electrical signal transmission function required for the detection module into a single main module to simplify the operation mode of the analysis device. Accordingly, the detection module of the present invention can be applied to an analysis device for detecting a sample liquid, and the analysis device has a liquid injection function and an electric signal transmission function, and has a relatively simple operation mode.

Although the present invention has been disclosed in the above embodiments, it is not intended to limit the present invention, and any one of ordinary skill in the art can make some changes and refinements without departing from the spirit and scope of the present invention. The scope of the invention is defined by the scope of the appended claims.

100‧‧‧Analytical device

110‧‧‧Test module

112‧‧‧First Ontology

112a, 112b‧‧‧ injection opening

114‧‧‧First electrical connector

Port 114a‧‧‧

116‧‧‧Detection wafer

120‧‧‧Main module

122‧‧‧Second ontology

124, 128‧‧‧Injection components

124a, 128a‧‧‧Fixed Department

124b, 128b‧‧‧ Insertion

126‧‧‧Second electrical connector

126a‧‧‧terminal

Claims (13)

An analysis device, comprising: a detection module, comprising: a first body having an injection opening, and a sample liquid is adapted to be disposed on the first body; a first electrical connector disposed on the first body And a detection chip disposed in the first body and electrically connected to the first electrical connector; and a main module, the detection module is adapted to be assembled to The main module includes: a second body; an injection component disposed on the second body; and a second electrical connector disposed on the second body and located at the injection component On one side, the detection module is adapted to connect to the main module with the injection opening corresponding to the injection element, and the first electrical connector is connected to the main module corresponding to the second electrical connector, wherein the injection element borrows a reagent liquid Injecting the first body from the injection opening, so that the sample liquid and the reagent liquid are mixed with each other in the first body, and the detecting wafer analyzes the mixed reagent liquid and the sample liquid to generate an electrical signal. The electrical signal by the Transmitting an electrical connector to the second electrical connector to the main module. The analysis device of claim 1, wherein the injection component A fixing portion and an insertion portion are included, and the injection member is fixed to the second body by the fixing portion, and is adapted to be inserted into the injection opening with the insertion portion. The analysis device of claim 1, wherein the detection module further comprises a sealing member disposed in the first body and corresponding to the injection opening. The analysis device of claim 3, wherein the sealing member is disposed in the injection opening and has a passage communicating with the injection opening, the injection member being adapted to be inserted into the first body from the injection opening and The channel is penetrated such that the reagent liquid is injected into the first body through the injection opening and the channel. The analysis device of claim 3, wherein the first body has a passage, the passage is connected to the injection opening, and the seal is disposed in the passage and has a through hole, and the injection element is adapted to be The injection opening is inserted into the first body and passes through the through hole to correspond to the passage, so that the reagent liquid is injected into the first body through the injection opening and the passage. A detection module includes: a first body having an injection opening, wherein a sample liquid is adapted to be disposed on the first body, and an injection element is adapted to inject a reagent liquid into the first through the injection opening a body such that the sample liquid and the reagent liquid are mixed with each other in the first body; a first electrical connector disposed on the first body and located on one side of the injection opening; and a detecting wafer Disposed in the first body and electrically connected to the first electrical connector, the detecting wafer analyzes the mixed reagent liquid and the sample liquid to produce An electrical signal is generated, and the electrical signal is transmitted to an analyzing device by the first electrical connector. The detection module of claim 6, further comprising: a sealing member disposed in the first body and corresponding to the injection opening. The detecting module of claim 7, wherein the sealing member is disposed at the injection opening and has a passage, the passage is connected to the injection opening, and the injection element is adapted to be inserted into the first body from the injection opening And penetrating into the channel, so that the reagent liquid is injected into the first body through the injection opening and the channel. The detection module of claim 7, wherein the first body has a passage, the passage is connected to the injection opening, and the seal is disposed in the passage and has a through hole, and the injection element is adapted to The injection opening is inserted into the first body and passes through the through hole to correspond to the passage, so that the reagent liquid is injected into the first body through the injection opening and the passage. The detection module of claim 6, further comprising: a micro-collector disposed on the first body, the micro-collector being adapted to receive and quantify the sample liquid, and the reagent liquid is suitable The sample liquid is carried by the micro-collector to be mixed with the sample liquid. The detection module of claim 6, further comprising: a first flow path disposed in the first body and connected to the injection opening and the sample liquid to allow the reagent liquid to be injected from the sample An opening flows into the first flow path and entrains the sample liquid. The detection module of claim 6, further comprising: a second flow path disposed in the first body and connected to the sample liquid and The detecting wafer is such that the reagent liquid and the sample liquid flow to the detecting wafer via the second flow path after being mixed with each other. The detection module of claim 12, further comprising: a mixing groove disposed in the first body and connected to the sample liquid and the second flow path, so that the reagent liquid is After the sample liquid is taken up, the sample liquid is mixed with each other in the mixing groove, and after being mixed with each other, flows to the detecting wafer via the second flow path.