TW202203894A - Oil-in-water type cosmetic emulsion preparation - Google Patents

Abstract

An oil-in-water type cosmetic emulsion preparation comprising the following ingredients (A) to (D): (A) 1-10 mass% niacinamide and/or tranexamic acid; (B) a silicone oil; (C) one or more glycerin derivatives selected from among ingredients (c1) represented by general formula (1) and ingredients (c2) represented by general formula (2); and (D) an amphipathic polymer.

Description

Oil-in-water emulsified cosmetic

The present invention relates to an oil-in-water emulsified cosmetic.

The skin can develop wrinkles or sagging, pigmentation such as spots or freckles due to internal factors such as aging or stress, or external factors such as UV rays or dry air. Among them, morphological changes such as wrinkles and sagging, and visual changes such as pigmentation affect the impression of appearance to a large extent, so many people want to improve, and various products are provided.

To prevent/improve wrinkles, sagging, pigmentation, many active ingredients have been proposed. Among them, niacinamide, which is an active ingredient for wrinkles and sagging, is known to be highly safe and has an anti-aging effect on the skin. In addition, the use of tranexamic acid has been proposed as a whitening agent for improving or inhibiting pigmentation. However, when a large amount of nicotinamide or tranexamic acid is contained, it is known that there is an unfavorable feeling in use, such as stickiness.

On the other hand, a technique for reducing stickiness and wrinkle improvement by blending nicotinamide, silicone oil with a viscosity of 25 mPa·s or less at 25°C, polyether-modified silicon, and carboxymethyl cellulose was disclosed ( For example, refer to Patent Document 1). Furthermore, it is disclosed that by combining two kinds of alkylene oxide derivatives, 2-methacryloyloxyethylphosphorylcholine-butyl methacrylate copolymer and polyol, it has a wrinkle-improving effect and has penetration during use The technology of a feeling lotion (for example, refer to Patent Document 2). [Prior Art Literature] [Patent Literature]

[Patent Document 1] Japanese Patent Laid-Open No. 2019-77675 [Patent Document 2] Japanese Patent Laid-Open No. 2015-74620

[The problem to be solved by the invention] However, in the techniques disclosed in Patent Document 1 and Patent Document 2, the lasting feeling of penetration and the feeling of moisturizing may be insufficient in some cases.

Therefore, an object of the present invention is to provide an oil-in-water emulsified cosmetic material using nicotinamide and/or tranexamic acid, silicone oil, and one or more selected from the group consisting of polyoxyalkylene-added glycerin derivatives represented by a specific formula. Two or more kinds, and an amphiphilic polymer, the oil-in-water emulsified cosmetic has excellent penetration feeling and is also excellent in lasting moisturizing feeling. [Means of Solving Problems]

In view of the above-mentioned actual situation, the inventors of the present invention have conducted intensive research, and as a result found that the oil-in-water emulsified cosmetic containing nicotinamide and/or tranexamic acid as active ingredients contains silicone oil selected from the group consisting of: The present invention has been accomplished by adding one or two or more of glycerol derivatives and an amphiphilic polymer to a polyoxyalkylene group to solve the above problems.

···（1） （式（1）中，Gly為自甘油中去除羥基後的殘基，PO為氧伸丙基，EO為氧伸乙基，l及m分別為PO及EO的平均加成莫耳數，（l+m）為1～60的值，質量比（PO/EO）為1/5～5/1，BO為碳數4的氧伸烷基，n為BO的平均加成莫耳數且為0～5的值） 成分（c2）通式（2） [化2]

···（2） （式（2）中，R表示-[CH₂ CH(CH₃ )O]-，p、q、r、s分別表示0～20的整數，p+q+r+s表示4～20的整數） （D）兩親媒性高分子。 [2] 如[1]所述的水中油型乳化化妝料，其中所述成分（D）為選自丙烯酸-甲基丙烯酸烷基酯共聚物、丙烯醯基二甲基牛磺酸銨/乙烯基吡咯啶酮共聚物、丙烯醯基二甲基牛磺酸銨甲基丙烯酸山萮醇聚醚-25共聚物、丙烯酸羥基乙酯/丙烯醯基二甲基牛磺酸Na共聚物、丙烯酸Na/丙烯醯基二甲基牛磺酸Na共聚物、聚乙二醇（Polyethylene Glycol，PEG）-240/癸基十四醇聚醚-20/六甲基二異氰酸酯共聚物、疏水化羥基丙基纖維素、羥基丙基澱粉磷酸中的至少一種。 [3] 如[1]或[2]所述的水中油型乳化化妝料，其中相對於水中油型乳化化妝料中所含的油劑總量，所述成分（B）的含量為60質量%以上。 [4] 如[1]～[3]中任一項所述的水中油型乳化化妝料，其中所述成分（C）的含量於水中油型乳化化妝料中為1質量%～20質量%。 [5] 如[1]～[4]中任一項所述的水中油型乳化化妝料，其中所述成分（D）的含量於水中油型乳化化妝料中為0.01質量%～0.4質量%。 [6] 如[1]～[5]中任一項所述的水中油型乳化化妝料，其中作為所述（A）成分，併用煙醯胺及凝血酸。 [7] 如[1]～[6]中任一項所述的水中油型乳化化妝料，其中所述成分（A）～成分（C）的含有質量比（A）/[（B）+（C）]為0.05以上且未滿7。 [8] 如[1]～[7]中任一項所述的水中油型乳化化妝料，其中所述成分（A）～成分（D）的含有質量比[（B）+（C）+（D）]/（A）為0.1以上且20以下。 [9] 如[1]～[8]中任一項所述的水中油型乳化化妝料，進而含有成分（E）聚甘油。 [發明的效果]That is, the present invention is an oil-in-water emulsified cosmetic containing an active ingredient for wrinkle, relaxation, and whitening, wherein the oil-in-water emulsified cosmetic is characterized by providing not only an excellent moisturizing feeling immediately after application, but also moisturizing It is an oil-in-water emulsified cosmetic which is also excellent in lasting feeling and penetrating feeling, and contains the following components (A) to (D). [1] An oil-in-water emulsified cosmetic, comprising the following components (A) to (D): (A) Niacinamide and/or tranexamic acid 1 mass % to 10 mass % (B) Silicone oil (C) Selected Glycerol derivative component (c1) of one or more of the components (c1) and (c2) represented by the following general formula

(1) (In formula (1), Gly is a residue obtained by removing a hydroxyl group from glycerol, PO is an oxypropylene group, EO is an oxyethylene group, and l and m are the average additions of PO and EO, respectively. The number of moles, (l+m) is a value of 1 to 60, the mass ratio (PO/EO) is 1/5 to 5/1, BO is an oxyalkylene group with a carbon number of 4, and n is the average addition of BO. It is a molar number and is a value of 0 to 5) Component (c2) General formula (2) [Chemical 2]

(2) (In formula (2), R represents -[CH ₂ CH(CH ₃ )O]-, p, q, r, and s represent integers from 0 to 20, respectively, p+q+r+s Integer representing 4 to 20) (D) Amphiphilic polymer. [2] The oil-in-water emulsified cosmetic according to [1], wherein the component (D) is selected from the group consisting of acrylic acid-alkyl methacrylate copolymer, ammonium acryldimethyltaurate/ethylene pyrrolidone copolymer, ammonium acryldimethyltaurate, beheneth-25 methacrylate copolymer, hydroxyethyl acrylate/acryloyldimethyltaurine Na copolymer, Na acrylate / Acryloyl dimethyl taurine Na copolymer, Polyethylene Glycol (PEG)-240/ Decyl tetradeceth-20/ Hexamethyl diisocyanate copolymer, Hydrophobized hydroxypropyl At least one of cellulose and hydroxypropyl starch phosphoric acid. [3] The oil-in-water emulsified cosmetic according to [1] or [2], wherein the content of the component (B) is 60% by mass relative to the total amount of oil agents contained in the oil-in-water emulsified cosmetic %above. [4] The oil-in-water emulsified cosmetic according to any one of [1] to [3], wherein the content of the component (C) is 1 to 20% by mass in the oil-in-water emulsified cosmetic . [5] The oil-in-water emulsified cosmetic according to any one of [1] to [4], wherein the content of the component (D) in the oil-in-water emulsified cosmetic is 0.01% by mass to 0.4% by mass . [6] The oil-in-water emulsified cosmetic according to any one of [1] to [5], wherein nicotinamide and tranexamic acid are used in combination as the (A) component. [7] The oil-in-water emulsified cosmetic according to any one of [1] to [6], wherein the components (A) to (C) are contained in a mass ratio (A)/[(B)+ (C)] is 0.05 or more and less than 7. [8] The oil-in-water emulsified cosmetic according to any one of [1] to [7], wherein the components (A) to (D) are contained in a mass ratio of [(B)+(C)+ (D)]/(A) is 0.1 or more and 20 or less. [9] The oil-in-water emulsified cosmetic according to any one of [1] to [8], further comprising a component (E) polyglycerin. [Effect of invention]

The oil-in-water emulsified cosmetic of the present invention is excellent not only in the penetrating feeling, but also in the moisturizing feeling immediately after application and the continuation of the moisturizing feeling. Furthermore, the oil-in-water emulsified cosmetic of the present invention is not sticky after use, and can provide a good feeling of use.

Hereinafter, embodiments of the present invention will be described. In addition, this invention is not limited only to the following embodiment. In this specification, "X to Y" indicating a range includes X and Y, and means "more than X and less than or equal to Y". In addition, unless otherwise stated, the measurement of operation, physical properties, etc. was performed under the conditions of room temperature (25° C.)/relative humidity 40% RH.

(Ingredient (A) niacinamide and/or tranexamic acid)

The component (A) nicotinamide used in the present invention is a nicotinamide compound of nicotinic acid (vitamin B3/nicotinic acid). Niacinamide is a water-soluble vitamin and is a known substance as one of the B vitamins, and can be extracted from natural products (rice bran, etc.) or synthesized by a known method. Specifically, those listed in the Seventeenth Revised Japanese Pharmacopoeia can be used.

The component (A) tranexamic acid used in the present invention is a kind of amino acid represented by the chemical name: trans-4-(aminomethyl)cyclohexane-1-carboxylic acid, except as described above as an anti-skin In addition to being known as a component having a whitening effect or an anti-inflammatory effect, it may also be used as a hemostatic agent.

From the viewpoint of the effect of the active ingredient, etc., the content of the ingredient (A) in the present invention is preferably 1 mass % or more (hereinafter, "mass %" is abbreviated as "%") in the oil-in-water emulsified cosmetic, More preferably, it is 2% or more, and still more preferably 5% or more. Moreover, content of a component (A) becomes like this. Preferably it is 10 % or less, More preferably, it is 8 % or less, More preferably, it is 7 % or less. If the content of the component (A) is less than 1%, satisfactory effects may not be obtained as an active ingredient, and if it exceeds 10%, stickiness during application may be strong, resulting in poor usability. In the present invention, the components (A) nicotinamide and tranexamic acid may be used alone or in combination, but are preferably used in combination from the viewpoint of their excellent effects as active ingredients such as skin antiaging effect and whitening effect. In the component (A), when two types of nicotinamide and tranexamic acid are used together, there exists a preferable range in each content. In the present invention, the content of the component (A) nicotinamide in the oil-in-water emulsified cosmetic is preferably 1% or more, more preferably 2% or more, and still more preferably 3% or more, preferably 4% or more. In addition, it is preferably less than 10%, more preferably 7% or less, and further more preferably 5% or less from the viewpoint of no feeling of use such as stickiness. In addition, the content of the component (A) tranexamic acid in the oil-in-water emulsified cosmetic is preferably 1% or more, more preferably 1.5% or more, and still more preferably 2% or more, from the viewpoint of the action as an active ingredient, etc. . In addition, it is preferably less than 10%, more preferably 5% or less, and still more preferably 3% or less from the viewpoint of no feeling of use such as stickiness.

(Ingredient (B) Silicone Oil)

The silicone oil of the component (B) used in the present invention can be used without particular limitation as long as it is commonly used in cosmetics. Although it does not specifically limit as a property of a silicone oil, It is more preferable that it is a liquid state at 25 degreeC from a viewpoint of excellent use feeling. Examples of these silicone oils include dimethicone, methylphenylpolysiloxane, octamethylcyclotetrasiloxane, decamethylcyclopentasiloxane, and methyltrimethicone. Oxane, polyether-modified methylpolysiloxane, oil-modified methylpolysiloxane, polyvinylpyrrolidone-modified methylpolysiloxane, octamethylcyclotetrasiloxane, dodecane Methylcyclohexasiloxane, Hexamethyldisiloxane, Octamethyltrisiloxane, Decamethyltetrasiloxane, Octyltrimethylsiloxane, Methylphenylpolysiloxane, Dimethyl Polysiloxane (Dimethiconol) etc. can select and use 1 type or 2 or more types of these suitably. In the present invention, it is preferable to use methylphenyl polysiloxane and/or dimethicone, and the use of dimethicone is more preferable because the penetrating feeling and the lasting feeling of moisturizing are obviously exhibited.

The viscosity of the dimethicone used in the present invention is not particularly limited, but from the viewpoint of penetrating feeling, the viscosity at 25°C is preferably 1 mPa·s to 200 mPa·s, more preferably 2 mPa·s s～100 mPa·s. In addition, the viscosity of a component (B) was measured according to the cosmetic raw material standard-viscosity measurement method 2 method using a Brookfield viscometer.

In the oil-in-water emulsified cosmetic of the present invention, even if the component (B) is contained in an amount of 60% or more with respect to the total amount of oil agents contained in the oil-in-water emulsified cosmetic, no sticky feeling, penetrating feeling and no stickiness can be obtained. Oil-in-water emulsified cosmetic with excellent moisturizing feeling. Moreover, in the system of this embodiment, it is preferable to make component (B) 60% or more of the total oil agent contained in the oil-in-water emulsified cosmetic. Therefore, the content of the component (B) in the total amount of oil agents contained in the oil-in-water emulsified cosmetic is preferably 60% or more, 70% or more, 80% or more, 85% or more, and 90% or more. In addition, the upper limit of the content of the component (B) in the total amount of oil agents contained in the oil-in-water emulsified cosmetic is 100%.

Examples of oil agents other than the component (B) include isododecane, isohexadecane, light isoalkane, liquid paraffin, squalane, squalene, α-olefin oligomers, polymer Butene, liquid isoalkane, heavy liquid isoalkane, polyisobutene, hydrogenated polyisobutene and other hydrocarbon oils; fatty acids such as oleic acid and isostearic acid; oleyl alcohol, 2-octyldodecanol, 2-decyl Higher alcohols such as tetradecanol, isostearyl alcohol, 2-hexyldecanol; fluorine-based oils such as perfluoropolyether, perfluorodecane, perfluorooctane; lanolin acetate, isopropyl lanolin fatty acid lanolin derivatives such as esters, lanolin alcohol; tri-2-ethylhexanoate, glyceryl diisostearate, diglyceryl Diglyceride fatty acid, trimethylolpropane triisostearate, diglyceryl tetraisostearate, polyglyceryl decaisostearate, isotridecyl isononanoate, tetra-2-ethyl Pentaerythritol Caproate, Pentaerythritol Tetraisostearate, Cetyl 2-Ethylhexanoate, Octyldodecyl Oleate, Tris(Caprylic/Capric) Glycerides, Dicapric Propylene Glycol, Myristic Acid Isopropyl, Isopropyl Palmitate, Octyldodecyl Myristate, Isohexadecyl Stearate, Neopentyl Glycol Dicaprylate, Di2-ethylhexyl Succinate, p-Methoxy 2-ethylhexyl cinnamate, ethylhexyl salicylate equal to liquid ester oils at 25°C; olive oil, macadamia nut oil, meadowfoam oil , jojoba oil, avocado oil, castor oil, safflower oil, sunflower oil, rapeseed oil (canola oil), almond oil, rice germ oil, rice bran oil, etc. vegetable oils that are liquid at 25°C; cocoa butter, milk Shea butter, castor oil, hardened castor oil, hardened coconut oil, petrolatum, hardened castor oil monostearate, hardened castor oil monohydroxystearate, cholesteryl hydroxystearate, dipentaerythritol fatty acid ester, N-lauryl-L-glutamic acid-bis(octyldodecyl/cholesteryl/behenyl), N-lauryl-L-glutamic acid-bis(octyldodecyl/ Phytosteryl (phytosteryl/ behenyl), macadamia nut oil fatty acid phytosterol, dimer dilinoleic acid (phytosteryl/isostearyl/hexadecyl/stearyl/behenyl) paste oils; paraffin, ceresin, microcrystalline wax, polyethylene wax, Fischer-Tropsch wax, stearic acid, behenic acid, cetyl palmitate, polyethylene glycol distearate , Glyceryl tribehenate, cholesterol, phytosterol, stearyl modified polysiloxane, hardened oil, petrolatum, palm oil, etc., are solid oil agents that are solid at 25°C. One or two or more of these can be used.

In the present invention, the content of the total amount of oil agents including the component (B) and the oil agents other than the component (B) is not particularly limited, and from the viewpoints of non-sticky feeling and continuation of moisturizing feeling, etc. In the oil-in-water emulsified cosmetic, it is preferably 0.2% or more, more preferably 0.5% or more, and still more preferably 1% or more. In addition, from the viewpoints of penetrating feeling, moisturizing feeling immediately after application, etc., the content of the total amount of oil agents including the component (B) and the oil agents other than the component (B) is in water oil-type emulsion makeup The content of the material is preferably 20% or less, more preferably 10% or less, and still more preferably 7% or less.

In addition, considering the lasting feeling of penetration and moisturizing, the content of hydrocarbon oil is preferably very small. For example, the content of hydrocarbon oil is preferably less than 1%, more preferably 0.5% or less in the oil-in-water emulsified cosmetic. , and more preferably not included (0%).

The content of the component (B) silicone oil in the present invention is not particularly limited, but is preferably 0.1% or more, more preferably 0.5% or more, in the oil-in-water emulsified cosmetic from the viewpoint of lasting moisturizing feeling. In addition, from the viewpoints of reducing stickiness and penetrating feeling, the content of the component (B) in the oil-in-water emulsified cosmetic is preferably 10% or less, more preferably 5% or less.

(Component (C) is selected from one or two or more glycerol derivatives of (c1) and (c2) represented by the following general formulas)

···（1） （式（1）中，Gly為自甘油中去除羥基後的殘基，PO為氧伸丙基，EO為氧伸乙基，l及m分別為PO及EO的平均加成莫耳數，（l+m）為1～60的值，質量比（PO/EO）為1/5～5/1，BO為碳數4的氧伸烷基，n為BO的平均加成莫耳數且為0～5的值） 成分（c2）通式（2） [化4]

···（2） （式（2）中，R表示-[CH₂ CH(CH₃ )O]-，p、q、r、s分別表示0～20的整數，p+q+r+s表示4～20的整數）The component (C) used in the present invention is one or two or more glycerol derivatives selected from the group consisting of the component (c1) and the component (c2) represented by the following general formula. Ingredient (c1) General formula (1) [Chemical 3]

(1) (In formula (1), Gly is a residue obtained by removing a hydroxyl group from glycerol, PO is an oxypropylene group, EO is an oxyethylene group, and l and m are the average additions of PO and EO, respectively. The number of moles, (l+m) is a value of 1 to 60, the mass ratio (PO/EO) is 1/5 to 5/1, BO is an oxyalkylene group with a carbon number of 4, and n is the average addition of BO. A molar number and a value of 0 to 5) Component (c2) General formula (2) [Chem. 4]

(2) (In formula (2), R represents -[CH ₂ CH(CH ₃ )O]-, p, q, r, and s represent integers from 0 to 20, respectively, p+q+r+s Represents an integer from 4 to 20)

That is, the component (c1) is obtained by adding propylene oxide and ethylene oxide to glycerin in a ratio of 3 to 180 molar equivalents in total relative to glycerin, or further to 0 relative to glycerin A carbon number 4 alkylene oxide is added at a ratio of to 15 molar equivalents. The glycerol derivative of the component (c1) can be obtained by adding an alkylene oxide having 4 carbon atoms in a block form after synthesizing an adduct of PO and EO at one time.

The mass ratio (PO/EO) of propylene oxide (PO) and ethylene oxide (EO) in the component (c1) is 1/5 to 5/1, and the addition form of propylene oxide and ethylene oxide It may be random or block. When the mass ratio (PO/EO) of propylene oxide (PO) and ethylene oxide (EO) is less than 1/5, the permeation feeling, the moisturizing feeling immediately after application, and the persistence of moisturizing feeling decrease , in the case of more than 5/1, there is no stickiness or reduced penetration.

The average number of added moles of propylene oxide (PO) and ethylene oxide (EO) of the component (c1) is preferably a total of 3 moles to 180 moles, that is, l+m is in the range of 1 to 60 From the viewpoints of penetrating feeling and moisturizing feeling, the average number of added moles of PO and EO is more preferably 3 moles to 150 moles in total, that is, l+m is within the range of 1 to 50, and PO and EO are in the range of 1 to 50. The average number of moles added is more preferably in the range of 3 moles to 90 moles in total, that is, l+m is in the range of 1 to 30. When the average number of added moles of PO and EO is less than 3 moles in total, that is, less than 1+m, there may be no stickiness and poor penetration. When the average number of added moles is 180 moles in total, that is, when l+m exceeds 60, the moisturizing feeling and the continuation of moisturizing feeling soon after may not be excellent.

In addition, the average added moles of propylene oxide (PO) of the component (c1) is preferably 3 moles to 90 moles, that is, within the range where l is 1 to 30, the average added moles of PO The number is more preferably in the range of 3 to 60, that is, l is in the range of 1 to 20. By setting it within this range, the effects of the present invention, such as the absence of stickiness or penetration, the moisturizing feeling immediately after application, and the continuation of the moisturizing feeling, can be more preferably exhibited.

The average number of added moles of alkylene oxide (BO) having 4 carbon atoms in the component (c1) is preferably 0 to 15 moles, that is, in the range where n is 0 to 5, the average addition of BO is The number of moles is more preferably 3 moles to 15 moles, that is, n is within the range of 1 to 5. When the average number of added mols of BO exceeds 15 mols, that is, when n exceeds 5, there may be no stickiness and poor penetration.

In the present invention, when the average number of added moles of alkylene oxide (BO) having 4 carbon atoms is 0 moles, that is, when n is 0, the average added moles of propylene oxide (PO) and ethylene oxide (EO) are The total number of moles is preferably 90 to 180 moles in total, that is, in the range where l+m is 30 to 60, and the average added moles of PO and EO are more preferably 90 to 150 moles in total, That is, l+m is in the range of 30-50. In addition, when the average added mol of BO is 1 to 5 mol, that is, when n is in the range of 1 to 5, the average added mol of PO and EO is preferably 3 to 90 in total. More preferably, the average added moles of PO and EO are within the range of 3 moles to 60 moles, that is, within the range of 1 to 20 for l+m. By setting it in the said range, the effect of this invention, such as non-sticky feeling and penetration feeling, the moisturizing feeling immediately after application|coating, and the continuation of moisturizing feeling, can be exhibited more, and it is preferable.

As a C4 alkylene oxide of the said component (c1), 1, 2- butylene oxide, 2, 3- butylene oxide, tetramethylene oxide (tetrahydrofuran), etc. are mentioned. Among these, 1,2-epoxybutane is preferable from the viewpoints of easiness of acquisition, easiness of reaction control, and the like.

Specifically, as the component (c1), the average added mole of (EO) is 8, the average added mole of (PO) is 5, and the average added mole of (BO) is 3. Oxybutylene polyoxyethylene polyoxypropylene glycerol ether (3BO) (8EO) (5PO), and the average added moles of (EO) is 24, the average added moles of (PO) The polyoxyethylene polyoxypropylene glyceryl ether (24EO) (24PO) which is 24 is preferable because the permeation feeling, the moisturizing feeling immediately after application, and the moisturizing feeling are continuously improved. Examples of these commercial products include polyoxyethylene (24) polyoxypropylene (24) glyceryl ether (marketing name: NIKKOL SG-G2424, manufactured by Nikko Chemical Co., Ltd.), polyoxyethylene Oxybutylene (3) Polyoxyethylene (8) Polyoxypropylene (5) Glyceryl ether (marketing name: WILBRIDE S-753, manufactured by NOF Corporation) and the like. One or two or more of these can be used.

The component (c2) of the present invention can be obtained by adding propylene oxide to diglycerol by a conventional method. Here, from the viewpoint of no stickiness, penetrating feeling, moisturizing feeling, etc., the number of added moles of propylene oxide in one molecule of diglycerol is preferably 4 moles to 20 moles, more preferably 5 moles. Molar to 15 moles, more preferably 8 to 15 moles, still more preferably 8 to 10 moles.

Specifically, as the component (c2), polyoxypropylene diglyceryl (9PO) having an average added molar number of (PO) of 9 is due to the penetrating feeling, the moisturizing feeling immediately after application, and the moisturizing feeling. Continue to improve, so it is better. As these commercial items, polyoxypropylene (9) diglyceryl (marketing name: SY-DP9, manufactured by Sakamoto Pharmaceutical Co., Ltd.) and the like are mentioned. One or two or more of these can be used.

As these glycerin derivatives of the component (c1) and the component (c2), when an alkylene oxide is added to glycerol or diglycerol, an alkali catalyst, a related mobile catalyst, a Lewis acid catalyst, etc. are used Addition reaction is carried out. In general, it is preferable to use an alkali catalyst such as potassium hydroxide.

In this invention, a component (C) may contain 1 type or 2 or more types chosen from a component (c1) and a component (c2). In the present invention, the component (C) is more preferably the component (c1) from the viewpoint that the effects such as the continuation of the moisturizing feeling can be more preferably exhibited. In addition, in the present invention, the term "component (C)" containing two types may be any of two types of components (c1), two types of components (c2), and a combination of components (c1) and (c2).

The content of the component (C) of the present invention is not particularly limited, but from the viewpoint of no stickiness or penetration, in the oil-in-water emulsified cosmetic, it is preferably 1% or more, more preferably 2% or more, and further More preferably, it is 3% or more. In addition, the content of the component (C) is more preferably 20% or less, and is preferably 15% or less, and still more preferably 10% or less, from the viewpoint of the moisturizing feeling immediately after application or the continuation of the moisturizing feeling.

In addition, the content mass ratio (A)/[(B)+(C)] of the components (A) to (C) is not particularly limited, but it is preferably 0.05 or more, more preferably 0.1 or more, so that there is no stickiness From the viewpoint of penetrating feeling or the like, it is more preferably 0.2 or more, and even more preferably 0.3 or more. In addition, from the viewpoint of the moisturizing feeling immediately after application or the continuation of moisturizing feeling, the content mass ratio (A)/[(B)+(C)] is preferably less than 7, more preferably 5 or less, More preferably, it is 3.5 or less, and even more preferably 2.5 or less.

(Component (D) Amphiphilic polymer)

The component (D) amphiphilic polymer used in the present invention means that it is used alone without using a surfactant, or even if a surfactant is used in combination, it is added in a small amount and can be stabilized in cosmetics and compositions. High molecular compound of oil-in-water emulsion dispersion. For example, acrylic acid-alkyl methacrylate copolymer, ammonium acryldimethyltaurate/vinylpyrrolidone copolymer, ammonium acryldimethyltaurate, behenyl methacrylate may be mentioned. Polyether-25 copolymer, hydroxyethyl acrylate/acryloyldimethyltaurine Na copolymer, acrylic acid Na/acryloyldimethyltaurine Na copolymer, PEG-240/decyltetradecyl Polyether-20/hexamethyldiisocyanate copolymer, hydrophobized hydroxypropyl cellulose, hydroxypropyl starch phosphoric acid, 2-methacryloyloxyphosphorylcholine-butyl methacrylate copolymer, can At least one of these ingredients is used.

Among these, it is preferable to use acrylic acid-alkyl methacrylate copolymer, ammonium acryldimethyltaurate/vinylpyrrole as the component (D) from the viewpoints of lasting feeling of penetration and moisturizing feeling, etc. Peridone Copolymer, Ammonium Acrylodimethyltaurate, Beheneth-25 Methacrylate Copolymer, Hydroxyethyl Acrylate/Acryloyldimethyltaurine Na Copolymer, Na Acrylate/Propylene Acrylodimethyltaurine Na copolymer, more preferably acrylic acid-alkyl methacrylate copolymer, ammonium acryldimethyltaurine methacrylate beheneth-25 copolymer, Acrylic acid Na/acryloyldimethyltaurine Na copolymer, more preferably acrylic acid-alkyl methacrylate copolymer, acrylyldimethyltaurate ammonium beheneth methacrylate -25 copolymer. As commercially available products, Aristoflex HMB (manufactured by Clariant Japan Co., Ltd.), PEMULEN TR-1 (Lubizol Advanced Materials) can be used manufacture) and the like, one or two or more of these can be used.

The content of the component (D) of the present invention is not particularly limited, but is preferably 0.01% or more in the oil-in-water emulsified cosmetic, and more preferably 0.05% or more from the viewpoint of lasting moisturizing feeling. In addition, the content of the component (D) is preferably 0.6% or less, more preferably 0.4% or less, and still more preferably 0.2% or less, from the viewpoints of penetrating feeling and the like.

In addition, in the oil-in-water emulsified cosmetic containing the component (A) of the present invention, it is important to combine the components (B) to (D) from the viewpoint of preferably exhibiting the effects of the present invention. In the present invention, the content mass ratio [(B)+(C)+(D)]/(A) of the component (A) to the component (D) is not particularly limited, but is preferably 0.1 or more, immediately after application From the viewpoint of the continuation of the moisturizing feeling or moisturizing feeling afterward, it is more preferably 0.2 or more, still more preferably 0.3 or more, and still more preferably 0.4 or more. In addition, from the viewpoint of no stickiness or penetration, the content mass ratio [(B)+(C)+(D)]/(A) is preferably 20 or less, more preferably 10 or less, and the From the viewpoint of the moisturizing feeling or the continuation of the moisturizing feeling soon after the cloth is applied, it is more preferably 5 or less, and particularly preferably 3 or less.

(Ingredient (E) Polyglycerol)

By further using the component (E) polyglycerin, the oil-in-water emulsified cosmetic of the present invention can be used as an oil-in-water emulsified cosmetic which is excellent in penetrating feeling, moisturizing feeling immediately after application, and lasting moisturizing feeling. In the present invention, the term "polyglycerol" refers to glycerol having a dimer or more, and examples thereof include diglycerol, triglycerol which is a trimer of glycerol, tetraglycerol which is a tetramer of glycerol, and hexamer which is glycerol. hexaglycerol, decaglycerol which is a decamer of glycerol, eicosglycerol which is an eicoser of glycerol, etc., one or two or more of these can be used. In the present invention, from the viewpoint of no stickiness, etc., one or two or more kinds selected from diglycerol and triglycerol are preferred, and the permeation feeling, the moisturizing feeling immediately after application, the continuation of moisturizing feeling, etc. are preferred. From a viewpoint, triglycerol is more preferable. As these commercial items, diglycerol 801, PGL-S (the above are manufactured by Sakamoto Pharmaceutical Co., Ltd.), etc. are mentioned.

The content of the component (E) of the present invention is not particularly limited, but is preferably 0.1% or more in the oil-in-water emulsified cosmetic, from the viewpoints of penetrating feeling, moisturizing feeling immediately after application, and continuation of moisturizing feeling. , more preferably 0.5% or more, still more preferably 1% or more. In addition, the content of the component (E) is preferably 5% or less, more preferably 3% or less, and still more preferably 2% or less, from the viewpoints of no stickiness, penetrating feeling, and the like.

In addition, in the present invention, the content ratio (C)/(E) of the component (C) and the component (E) is not particularly limited, but it is more suitable from the viewpoints of the moisturizing feeling immediately after application or the continuation of the moisturizing feeling. It is preferably 1 or more, more preferably 2 or more, and still more preferably 3 or more. In addition, from the viewpoint of no sticky feeling, penetrating feeling, etc., the content mass ratio (C)/(E) is preferably 15 or less, more preferably 10 or less, and still more preferably 7 or less.

The present invention is an oil-in-water emulsified cosmetic and an oil-in-water emulsified cosmetic containing water. Here, water can be used as a dispersion medium of the oil agent, and it is not particularly limited as long as it is water generally used in cosmetics, and examples thereof include purified water, distilled water, ion-exchanged water, tap water, hot spring water, and deep ocean water. Wait. The content of water is not particularly limited, but is preferably 10% to 80%, more preferably 20% to 70% in the oil-in-water emulsified cosmetic.

Furthermore, in the oil-in-water emulsified cosmetic of the present invention, a surfactant may be contained within a range that does not impair the effects of the present invention. Surfactants can improve the stability of oil-in-water emulsified cosmetics, and can be formulated without particular restrictions as long as they are commonly used in cosmetics, quasi drugs, pharmaceuticals, and the like. However, from the viewpoint of improving the stability and maintaining the usability such as stickiness and penetrating feeling, and the continuation of moisturizing feeling, it is preferably 3% or less, more preferably 1% or less.

The oil-in-water emulsified cosmetic of the present invention may contain, in addition to the above-mentioned essential components, components generally usable in cosmetics, quasi-drugs, pharmaceuticals, and the like, within a range that does not impair the effects of the present invention. That is, the oil-in-water emulsified cosmetic of the present invention may suitably contain, for example, surfactants, higher alcohols, water-soluble polymers other than component (D), lower alcohols, and polyols within a range that does not impair the effects of the present invention. , Film formers, powders, resins, fragrances, deodorants, cooling agents, UV absorbers, pH adjusters, preservatives, chelating agents, plant extracts, amino acids, vitamins, beauty ingredients, etc.

The oil-in-water emulsified cosmetic of the present invention can be used as a cosmetic for various applications. For example, cosmetics such as lotion, lotion, face cream, cosmetic lotion, massage cosmetic, facial mask, hand cream, body lotion, body cream, cosmetic cosmetic, cosmetic base, eye cream, and sunscreen can be exemplified. . Among them, skin care cosmetics such as lotion, lotion, face cream, cosmetic lotion, massage cosmetic, facial mask cosmetic, hand cream, body lotion, and body cream are preferable. As the usage method, the method of using with a hand, a finger, or cotton, and the method of impregnating a nonwoven fabric or the like and using it, etc. are mentioned.

As the properties of the oil-in-water emulsified cosmetic of the present invention, various forms such as liquid, gel, emulsion, cream, semi-solid, and solid can be implemented, and among them, the effects of the present invention are obtained. , preferably in liquid to gel form. Here, the term "liquid state to gel state" refers to those having a viscosity of 30,000 mPa·s or less as measured by a Brookfield rotational viscometer at 25°C, preferably 20,000 mPa·s or less, and more preferably 15,000 mPa·s or less.

(Production method) The production method of the oil-in-water emulsified cosmetic of the present invention is not particularly limited, and can be usually produced by a known method, and specific examples thereof include a dispersion emulsification method, a phase inversion emulsification method, and a phase inversion temperature emulsification method. As a manufacturing facility, if it is a dispersion-emulsification facility such as general dispersion, any one may be used. For example, the oil phase in which the component (B) is heated and dissolved is added to the water phase obtained by mixing and dissolving the components (C) to (E) with a part of purified water, emulsified and mixed by dispersion, and then cooled and added. The component (A) dissolved in purified water can obtain an oil-in-water emulsified cosmetic. [Example]

The effect of this invention is demonstrated using the following Example and a comparative example. However, the technical scope of the present invention is not limited only to the following examples. In addition, unless otherwise stated, each operation was performed at room temperature (25 degreeC). Example 1 to Example 24 and Comparative Example 1 to Comparative Example 9: Oil-in-water emulsified cosmetic The oil-in-water emulsified cosmetics of the formulations shown in the following Tables 1 to 3 were prepared, and the non-sticky feeling, the permeation feeling, the moisturizing feeling immediately after application, and the continuation of the moisturizing feeling were evaluated by the following methods. The results are also shown in Tables 1 to 3 together.

[Table 1] quality% No Element Example 1 2 3 4 5 6 7 8 9 10 11 12 1 Niacinamide (ingredient (A)) 4 2 7.5 5 5 4 4 4 4 4 4 4 2 tranexamic acid (ingredient (A)) 3 5 2 5 2 3 3 3 3 3 3 3 3 Dimethicone (2 mPa·s at 25°C) (Component (B)) 1 1 1 1 1 5 0.5 1 1 0.5 1 1 4 Methylphenylpolysiloxane (ingredient (B)) - - - - - - - - - - - - 5 Liquid Paraffin Note 1 - - - - - - - - - - - - 6 PEG/PPG/Polybutylene Glycol-8/5/3 Glycerin Note 2 (Ingredient (C)) 5 5 5 5 5 5 5 15 1 1 - - 7 PPG-24 Glycerol-24 Note 3 (ingredient (C)) - - - - - - - - - - 5 - 8 PPG-9 Diglyceryl Note 4 (Ingredient (C)) - - - - - - - - - - - 5 9 glycerin - - - - - - - - - - - - 10 Glycerol polyether-26 Note 5 - - - - - - - - - - - - 11 PPG-7 - - - - - - - - - - - - 12 (Acrylic acid/Alkyl Acrylate (C-10-30)) Cross-linked polymer Note 6 (Component (D)) 0.2 0.2 0.02 0.2 0.2 0.2 0.2 0.2 0.2 0.2 0.2 0.2 13 (Ammonium Acrylodimethyltaurate/Beheneth-25 Methacrylate) Crosspolymer Note 7 (Ingredient (D)) - - - - - - - - - - - - 14 Carboxy vinyl polymer - - - - - - - - - - - - 15 Xanthan Gum - - - - - - - - - - - - 16 Polyglycerol-3 Note 16 (Ingredient (E)) - - - - - - - - - - - - 17 BG 15 15 15 15 15 15 15 15 15 15 15 15 18 sodium hydroxide 0.05 0.05 0.05 0.05 0.05 0.05 0.05 0.05 0.05 0.05 0.05 0.05 19 Ethanol 1 1 1 1 1 1 1 1 1 1 1 1 20 purified water The remaining amount The remaining amount The remaining amount The remaining amount The remaining amount The remaining amount The remaining amount The remaining amount The remaining amount The remaining amount The remaining amount The remaining amount Contains mass ratio (A)/[(B)+(C)] 1.2 1.2 1.6 1.7 1.2 0.7 1.3 0.4 3.5 4.7 1.2 1.2 Contains mass ratio [(B)+(C)+(D)]/(A) 0.9 0.9 0.6 0.6 0.9 1.5 0.8 2.3 0.3 0.2 0.9 0.9 <Items and Judgment Results> A No sticky feeling ◎ ◎ ○ ○ ◎ ◎ ○ ○ ◎ ◎ ◎ ◎ (average rating) 3.4 3.6 2.7 2.6 3.3 3.8 3.1 3.0 3.7 3.6 3.4 3.4 B Penetration ◎ ◎ ◎ ◎ ◎ ○ ◎ ◎ ◎ ◎ ◎ ◎ (average rating) 3.5 3.5 3.7 3.5 3.5 3.1 3.6 3.3 3.6 3.7 3.5 3.5 C Moisturizing feeling immediately after application ◎ ◎ ◎ ◎ ◎ ○ ◎ ◎ ○ ○ ◎ ◎ (average rating) 3.5 3.5 3.3 3.5 3.5 3.2 3.5 3.8 3.0 3.0 3.5 3.5 D Sustained moisturizing ◎ ◎ ◎ ◎ ◎ ◎ ○ ◎ ○ ○ ◎ ○ (average rating) 3.5 3.5 3.3 3.5 3.5 3.7 3.0 3.9 2.8 2.6 3.5 3.2

[Table 2] quality% No Element Example 13 14 15 16 17 18 19 20 twenty one twenty two twenty three twenty four 1 Niacinamide (ingredient (A)) 4 4 4 - 1 - 10 - 5 4 4 4 2 tranexamic acid (ingredient (A)) 3 3 3 2 - 1 - 10 - 3 3 3 3 Dimethicone (2 mPa·s at 25°C) (Component (B)) 1 1 1 1 5 5 1 1 1 0.6 - 1 4 Methylphenylpolysiloxane (ingredient (B)) - - - - - - - - - - 1 - 5 Liquid Paraffin Note 1 - - - - - - - - - 0.4 - - 6 PEG/PPG/Polybutylene Glycol-8/5/3 Glycerin Note 2 (Ingredient (C)) 5 5 5 5 15 15 5 5 5 5 5 5 7 PPG-24 Glycerol-24 Note 3 (ingredient (C)) - - - - - - - - - - - - 8 PPG-9 Diglyceryl Note 4 (Ingredient (C)) - - - - - - - - - - - - 9 glycerin - - - - - - - - - - - - 10 Glycerol polyether-26 Note 5 - - - - - - - - - - - - 11 PPG-7 - - - - - - - - - - - - 12 (Acrylic acid/Alkyl acrylate (C-10-30)) Cross-linked polymer Note 6 (ingredient (D)) 0.4 0.01 - 0.2 0.2 0.2 0.02 0.02 0.2 0.2 0.2 0.2 13 (Ammonium Acrylodimethyltaurate/Beheneth-25 Methacrylate) Crosspolymer Note 7 (Ingredient (D)) - - 0.2 - - - - - - - - - 14 Carboxy vinyl polymer - - - - - - - - - - - - 15 Xanthan Gum - - - - - - - - - - - - 16 Polyglycerol-3 Note 16 (Ingredient (E)) - - - - - - - - - - - 1 17 BG 15 15 15 15 15 15 15 15 15 15 15 15 18 sodium hydroxide 0.05 0.05 0.05 0.05 0.05 0.05 0.05 0.05 0.05 0.05 0.05 0.05 19 Ethanol 1 1 1 1 1 1 1 1 1 1 1 1 20 purified water The remaining amount The remaining amount The remaining amount The remaining amount The remaining amount The remaining amount The remaining amount The remaining amount The remaining amount The remaining amount The remaining amount The remaining amount Contains mass ratio (A)/[(B)+(C)] 1.2 1.2 1.2 0.3 0.05 0.05 1.7 1.7 0.8 1.3 1.2 1.2 Contains mass ratio [(B)+(C)+(D)]/(A) 0.9 0.9 0.9 3.1 20 20 0.6 0.6 1.2 0.8 0.9 0.9 <Items and Judgment Results> A No sticky feeling ○ ◎ ◎ ◎ ○ ○ ○ ○ ◎ ○ ◎ ○ (average rating) 3.2 3.8 3.6 3.8 3.2 3.2 3.0 3.0 3.7 3.2 3.4 3.1 B Penetration ○ ◎ ◎ ◎ ○ ○ ◎ ◎ ◎ ◎ ○ ◎ (average rating) 2.9 3.8 3.7 3.5 2.9 2.9 3.7 3.7 3.5 3.5 3.2 3.6 C Moisturizing feeling immediately after application ◎ ◎ ◎ ◎ ◎ ◎ ◎ ◎ ◎ ◎ ◎ ◎ (average rating) 3.7 3.3 3.4 3.5 3.3 3.3 3.3 3.3 3.5 3.5 3.3 3.8 D Sustained moisturizing ◎ ○ ◎ ◎ ◎ ◎ ◎ ◎ ◎ ○ ◎ ◎ (average rating) 3.4 3.0 3.3 3.5 3.8 3.8 3.3 3.3 3.5 3.2 3.6 3.9

[table 3] quality% No Element Comparative example 1 2 3 4 5 6 7 8 9 1 Niacinamide (ingredient (A)) 5 5 5 5 5 5 5 5 5 2 tranexamic acid (ingredient (A)) 2 2 2 2 2 2 2 2 2 3 Dimethicone (2 mPa·s at 25°C) (Component (B)) - - 1 1 1 1 1 1 1 4 Methylphenylpolysiloxane (ingredient (B)) - - - - - - - - - 5 Liquid Paraffin Note 1 - 1 - - - - - - - 6 PEG/PPG/Polybutylene Glycol-8/5/3 Glycerin Note 2 (Ingredient (C)) 5 5 - - - - 5 5 5 7 PPG-24 Glycerol-24 Note 3 (ingredient (C)) - - - - - - - - - 8 PPG-9 Diglyceryl Note 4 (Ingredient (C)) - - - - - - - - - 9 glycerin - - - 5 - - - - - 10 Glycerol polyether-26 Note 5 - - - - 5 - - - - 11 PPG-7 - - - - - 5 - - - 12 (Acrylic acid/Alkyl Acrylate (C-10-30)) Cross-linked polymer Note 6 (Component (D)) 0.2 0.2 0.2 0.2 0.2 0.2 - - - 13 (Ammonium Acrylodimethyltaurate/Beheneth-25 Methacrylate) Crosspolymer Note 7 (Ingredient (D)) - - - - - - - - - 14 Carboxy vinyl polymer - - - - - - - 0.2 - 15 Xanthan Gum - - - - - - - - 0.2 16 Polyglycerol-3 Note 16 (Ingredient (E)) - - - - - - - - - 17 BG 15 15 15 15 15 15 15 15 15 18 sodium hydroxide 0.05 0.05 0.05 0.05 0.05 0.05 0.05 0.05 0.05 19 Ethanol 1 1 1 1 1 1 1 1 1 20 purified water The remaining amount The remaining amount The remaining amount The remaining amount The remaining amount The remaining amount The remaining amount The remaining amount The remaining amount Contains mass ratio (A)/[(B)+(C)] 1.4 1.4 7.0 7.0 7.0 7.0 1.2 1.2 1.2 Contains mass ratio [(B)+(C)+(D)]/(A) 0.7 0.7 0.2 0.2 0.2 0.2 0.9 0.9 0.9 <Items and Judgment Results> A No sticky feeling × × △ × × △ △ △ △ (average rating) 1.6 1.7 2.5 1.6 1.6 1.8 2.5 2.4 2.0 B Penetration △ △ △ × × △ △ △ △ (average rating) 2.5 2.2 2.5 1.7 1.7 2.2 2.5 2.4 2.1 C Moisturizing feeling immediately after application × △ × △ △ △ △ △ △ (average rating) 1.7 2.5 1.3 2.5 2.5 2.5 2.2 2.5 2.5 D Sustained moisturizing × × × △ △ × × × × (average rating) 1.7 1.7 1.0 2.5 2.5 1.7 1.1 1.7 1.7 Note 1 Carnation (manufactured by SONNEBORN) Note 2 WILBRIDE S-753D (manufactured by NOF Corporation) Note 3 NIKKOL SG-G2424 ( Nikko Chemical Co., Ltd.) Note 4 SY-DP9 (manufactured by Sakamoto Pharmaceutical Co., Ltd.) Note 5 LIPONIC EG-1 (manufactured by Lipo Chemicals) Note 6 Pimulun ( PEMULEN) TR-1 (manufactured by Lubrizol Advanced Materials) Note 7 Aristoflex HMB (manufactured by Clariant Japan Co., Ltd.) Note 16 PGL-S (Sakamoto Pharmaceuticals) manufactured by industrial companies)

(Production method) A: The components (6) to (19) and a part of the components (20) are uniformly mixed and dissolved. B: Component (3) to (5) are uniformly mixed and dissolved. C: Emulsify by adding B to A, and then add and mix the component (1) and the component (2) dissolved in the remaining component (20) to obtain an oil-in-water emulsified cosmetic.

(Evaluation method 1) Women in their 20s and 40s are trained in sensory evaluation, and 10 professional panelists who can evaluate according to certain criteria are selected. 2 g of each sample was used on the forearm of this expert panelist, and the following absolute evaluations were used to evaluate the non-sticky feeling at the time of use, the penetrating feeling, and the moisturizing feeling immediately after application, respectively, and scored. For each sample, the scores of all the panelists were totaled, the average value was calculated, and the judgment was made according to the following four-level judgment criteria.

(A: No sticky feeling) <Absolute Evaluation Criteria> (rating): (rating) 4 points: No stickiness is felt 3 points: Almost no stickiness is felt 2 points: Slightly sticky 1 point: feel sticky <Four-level judgment criteria> (judgment): (average of ratings) ◎: more than 3.25 points : very good ○: More than 2.5 points and less than 3.25 points : Good △: More than 1.75 points and less than 2.5 points : Slightly defective ×: Less than 1.75 points : Bad

(B: penetrating feeling) <Absolute Evaluation Criteria> (rating): (rating) 4 points: A feeling of penetration into the skin is felt 3 points: There is a slight feeling of penetration into the skin 2 points: Almost no feeling of penetration into the skin 1 point: No feeling of penetration into the skin <Four-level judgment criteria> (judgment): (average of ratings) ◎: more than 3.25 points : very good ○: More than 2.5 points and less than 3.25 points : Good △: More than 1.75 points and less than 2.5 points : Slightly defective ×: Less than 1.75 points : Bad

(C: Moisturizing feeling immediately after application) <Absolute Evaluation Criteria> (rating): (rating) 4 points: A feeling of moisturizing is felt 3 points: A slightly moisturizing feeling is felt 2 points: Almost no moisturizing feeling is felt 1 point: No feeling of moisturizing <Four-level judgment criteria> (judgment): (average of ratings) ◎: more than 3.25 points : very good ○: More than 2.5 points and less than 3.25 points : Good △: More than 1.75 points and less than 2.5 points : Slightly defective ×: Less than 1.75 points : Bad

(Evaluation method 2) Women in their 20s and 40s are trained in sensory evaluation, and 10 professional panelists who can evaluate according to certain criteria are selected. This expert panelist applied 2 g of each sample to the forearm and allowed it to penetrate, and evaluated the continuation of the moisturizing feeling 5 hours after application on a four-level scale according to the following absolute evaluation and scored. For each sample, the scores of all the panelists were totaled, the average value was calculated, and the judgment was made according to the following four-level judgment criteria.

(D: Continuation of moisturizing feeling) <Absolute Evaluation Criteria> (rating): (rating) 4 points: A feeling of moisturizing is felt 3 points: A slightly moisturizing feeling is felt 2 points: Almost no moisturizing feeling is felt 1 point: No feeling of moisturizing <Four-level judgment criteria> (judgment): (average of ratings) ◎: more than 3.25 points : very good ○: More than 2.5 points and less than 3.25 points : Good △: More than 1.75 points and less than 2.5 points : Slightly defective ×: 1.75 points or less : Bad

From the results in Tables 1 to 3, it is understood that the oil-in-water emulsified cosmetics of Examples 1 to 24 of the present invention are less sticky than the oil-in-water emulsified cosmetics of Comparative Examples 1 to 9, and have The penetration feeling, the moisturizing feeling immediately after application, and the continuation of the moisturizing feeling are also excellent.

On the other hand, in Comparative Examples 1 and 2 that did not contain the silicone oil as the component (B) or used liquid paraffin as the hydrocarbon oil, there was no sticky feeling or lasting moisturizing feeling, and the penetrating feeling or just-applied feeling was poor. The moisturizing feeling after cloth was not satisfactory. Furthermore, a glycerol derivative or glycerol added to a polyoxyalkylene group represented by a specific formula that does not contain the component (C), or a polyoxyalkylene skeleton containing no polyoxypropylene skeleton is used to add glycerin, In Comparative Examples 3 to 6 of the polypropylene glycol containing no glycerin skeleton, satisfactory ones were not obtained in all the results such as the permeation feeling and the continuation of the moisturizing feeling. In addition, in Comparative Examples 7 to 9 in which the component (D) amphiphilic polymer was not contained, or the water-soluble polymer or water-soluble polysaccharide that did not have amphiphilicity was used, the continuation of the osmotic feeling was not observed. In addition, it is not satisfactory in terms of no stickiness, penetration, and moisturizing feeling immediately after application.

Example 25: Cosmetic liquid (oil-in-water type) (ingredients) (mass %) (1) Niacinamide (ingredient (A)) 3 (2) tranexamic acid (component (A)) 2 (3) (acrylic acid/alkyl acrylate (C10-30)) copolymer (Ingredient (D)) Note 6 0.3 (4) Ammonium Acryloyldimethyltaurate/Methacrylic Acid Beheneth-25 Crosspolymer Component (D)) Note 7 0.05 (5) 1,3-Butanediol 8 (6) Remaining amount of purified water (7) Glycerin 5 (8) EDTA-2Na 0.01 (9) Sodium hydrogen phosphate 0.3 (10) Sodium dihydrogen phosphate 0.6 (11) PEG/PPG/polybutylene glycol /8/5/3 Glycerin (ingredient (C)) Note 2 3 (12) Diglycerol 1 (13) Aureobasidium pullulans culture 5 (14) Refined water 5 (15) Sodium hydroxide 0.07 (16) Dimethicone (10 mPa·s at 25°C) (Ingredient (B)) 1.5 (17) Dimethicone (2 mPa·s at 25°C) (ingredient (B)) 1 (18) Triethylhexanoin 1 (19) Liquid Paraffin Note 1 0.5 (20) Ethanol 5 (21) Spices 0.05 (22) Phenoxyethanol 0.2 (23) Ethylhexylglycerol 0.06 (24) PEG-11 methyl ether dimethyl polysiloxane Note 8 0.5 (25) PEG-9 Dimethicone Note 9 0.1 (26) Vitamin E 0.03 Note 8 KF-6018 (manufactured by Shin-Etsu Chemical Co., Ltd.) Note 9 KF-6019 (manufactured by Shin-Etsu Chemical Co., Ltd.)

(Production method) A: Component (1) to (15) are uniformly mixed. B: After mixing and dissolving the components (16) to (26), it is added to the above-mentioned A at room temperature and emulsified. C: B was filled in a container, and the cosmetic liquid was obtained.

The cosmetic liquid of Example 25 obtained as described above was excellent in continuation of moisturizing feeling without stickiness, penetrating feeling, moisturizing feeling immediately after application, and moisturizing feeling. In addition, the content mass ratio (A)/[(B)+(C)] of a component (A) - a component (C) was 0.9.

Example 26: Emulsion (oil in water type) (ingredients) (mass %) (1) Niacinamide (ingredient (A)) 3 (2) tranexamic acid (component (A)) 2 (3) (acrylic acid/alkyl acrylate (C10-30)) copolymer (Ingredient (D)) Note 6 0.15 (4) Carboxy vinyl polymer 0.06 (5) 1,3-Butanediol 8 (6) Remaining amount of purified water (7) Glycerin 5 (8) EDTA-2Na 0.01 (9) Polyoxypropylene (9) Diglyceryl (ingredient (C)) Note 4 2 (10) PEG/PPG/polybutylene glycol /8/5/3 Glycerin (ingredient (C)) Note 2 3 (11) Polyoxyethylene glycerol (26E.O.) Note 5         1 (12) Polyglyceryl-3 (ingredient (E)) Note 16 0.5 (13) Aureobasidium pullulans culture 5 (14) Refined water 5 (15) Sodium hydroxide 0.08 (16) Dimethylsiloxane (6 mPa·s at 25°C) (ingredient (B)) 5 (17) Macadamia Oil Fatty Acid Phytosterols Note 10       1 (18) Phytosterol Oleate Note 11 0.1 (19) Ethanol 3 (20) Spices 0.2 (21) Phenoxyethanol 0.2 (22) Ethylhexylglycerol 0.06 (23) PEG-11 methyl ether dimethyl polysiloxane Note 8 0.8 (24) PEG-9 Dimethicone Note 9 0.2 (25) Vitamin E 0.03 Note 10 LANDOOL-MAS (manufactured by Nippon Seika Co., Ltd.) Note 11 Riceterol Ester (manufactured by Tsukino Rice Refining Co., Ltd.)

(Production method) A: Component (1) to (15) are uniformly mixed. B: The components (16) to (25) were heated to about 70° C., mixed and dissolved uniformly, and then added to the above-mentioned A, emulsified, and then cooled. C: B was filled in a container, and an emulsion was obtained.

The emulsion (oil-in-water type) of Example 26 obtained as described above was excellent in no sticky feeling, penetration feeling, moisturizing feeling immediately after application, and continuation of moisturizing feeling. In addition, the content mass ratio (A)/[(B)+(C)] of a component (A) - a component (C) is 0.5.

Example 27: Sunscreen (oil-in-water type) (ingredients) (mass %) (1) 1,3-Butanediol 5 (2) Dipropylene glycol 5 (3) Behentrimonium Chloride 0.1 (4) Hydrogenated lecithin Note 12 0.5 (5) Cholesterol Note 13 0.6 (6) Plant sterols 0.1 (7) PEG/PPG/polybutylene glycol /8/5/3 Glycerin (ingredient (C)) Note 2 1 (8) Remaining amount of purified water (9) Niacinamide (ingredient (A)) 3 (10) tranexamic acid (component (A)) 2 (11) (acrylic acid/alkyl acrylate (C10-30)) Copolymer (ingredient (D)) Note 6 0.4 (12) Triethanolamine 0.4 (13) Dimethicodiethylbenzalmalonate 1.2 (14) 4-tert-butyl-4'-methoxy-dibenzylmethane 2 (15) 2-ethylhexyl p-methoxycinnamic acid 7 (16) Hexyl diethylamino hydroxybenzoyl benzoate 2.5 (17) Dimethicone (100 mPa·s at 25°C) (ingredient (B)) 1 (18) Stearic acid hardened castor oil Note 14 0.5 (19) Propylene Glycol Dicaprate 5 (20) Ethyl oleate 0.3 (21) Natural vitamin E 0.1 (22) Rosemary Oil 0.01 (23) 1,2-pentanediol 0.1 (24) Zinc oxide 2 (25) Water-soluble collagen 0.01 (26) Chamomile Extract 0.05 (27) Don Calendula Extract 0.05 (28) Glycerin 1 (29) Ethanol 7 (30) Spices 0.1 Note 12 Nikkor Resinol S-10 (manufactured by Nikkor Chemical Co., Ltd.) Note 13 Kairei Marine Cholesterol (manufactured by Nippon Fisheries Corporation) Note 14 Castride MS (manufactured by National Mimatsu Corporation)

(Production method) A: The components (1) to (7) were uniformly dissolved and mixed at 75°C. B: Component (8) to (12) were uniformly dissolved and mixed at 70°C. C: The components (13) to (22) were uniformly dissolved and mixed at 80°C. D: B and C were added to A, and it was emulsified at 70 degreeC. E: After adding the mixed component (23) - component (30) to D, it cooled to 40 degreeC, and obtained the sunscreen (oil-in-water type).

The sunscreen agent (oil-in-water type) of Example 27 obtained as described above was excellent in non-sticky feeling, penetrating feeling, moisturizing feeling immediately after application, and continuation of moisturizing feeling. In addition, the content mass ratio (A)/[(B)+(C)] of a component (A) - a component (C) was 2.5.

Example 28: Lotion (oil in water type) (ingredients) (mass %) (1) PEG-20 hydrogenated castor oil 0.5 (2) Tris (palm oil fatty acid/palm kernel oil fatty acid/olive oil fatty acid) / Macadamia Oil Fatty Acids / Rapeseed Oil Fatty Acids) Glyceryl Note 15 0.07 (3) Oleic acid phytosterols 0.01 (4) Dimethicone (6 mPa·s at 25°C) (component (B)) 0.13 (5) Vitamin E 0.01 (6) Niacinamide (ingredient (A)) 3 (7) tranexamic acid (component (A)) 2 (8) Ammonium acryloyldimethyltaurate/methacrylic acid Beheneth-25 Crosspolymer Note 7 Ingredient (D)) 0.05 (9) 1,3-Butanediol 8 (10) Glycerin 5 (11) EDTA-2Na 0.01 (12) Sodium hydrogen phosphate 0.1 (13) Sodium dihydrogen phosphate 0.2 (14) PEG/PPG/polybutylene glycol /8/5/3 Glycerin (ingredient (C)) Note 2 1 (15) Diglycerol 0.5 (16) Methylgluceth-10 0.5 (17) Aureobasidium pullulans culture 1 (18) Sodium hydroxide 0.02 (19) Ethanol 2 (20) Isostearate PEG-50 Hydrogenated Castor Oil 0.1 (21) Spices 0.02 (22) Phenoxyethanol 0.2 (23) Ethylhexylglycerol 0.06 (24) Remaining amount of purified water Note 15 HS Oil G-AP (manufactured by National Mimatsu Corporation)

(Production method) A: The components (1) to (5) are uniformly dissolved and mixed at 75°C. B: A part was added while maintaining A at 75 degreeC, and it emulsified at 70 degreeC. C: After cooling B to room temperature, high-pressure treatment (treatment pressure 200) was performed using a microfluidizer. D: The remainder of the components (6) to (23) and the component (24) were uniformly dissolved and mixed at room temperature. E: By adding and mixing C to D, a lotion is obtained.

The lotion (oil-in-water type) of Example 28 obtained as described above was excellent in no sticky feeling, penetration feeling, moisturizing feeling immediately after application, and continuation of moisturizing feeling. In addition, the content mass ratio (A)/[(B)+(C)] of a component (A) - a component (C) was 4.4.

without

without

Claims (9)

An oil-in-water emulsified cosmetic, comprising the following components (A) to (D): (A) nicotinamide and/or tranexamic acid, the content of which is 1% by mass to 10% by mass (B) silicone oil (C) Glycerol derivative component (c1) of one or two or more of the components (c1) and (c2) represented by the following general formula: general formula (1)

(1) In formula (1), Gly is a residue obtained by removing a hydroxyl group from glycerol, PO is an oxypropylene group, EO is an oxyethylene group, and l and m are the average additions of PO and EO, respectively. Molar number, (l+m) is a value from 1 to 60, the mass ratio, that is, PO/EO, is 1/5 to 5/1, BO is an oxyalkylene group with carbon number 4, and n is the average addition molar of BO. The number of ears is a value from 0 to 5, component (c2) general formula (2)

(2) In formula (2), R represents -[CH ₂ CH(CH ₃ )O]-, p, q, r, and s each represent an integer of 0 to 20, and p+q+r+s represents An integer of 4 to 20, (D) an amphiphilic polymer. The oil-in-water emulsified cosmetic according to claim 1, wherein the component (D) is selected from the group consisting of acrylic acid-alkyl methacrylate copolymer, ammonium acryldimethyltaurate/vinylpyrrolidine Ketone Copolymer, Ammonium Acrylodimethyltaurate, Beheneth-25 Copolymer, Hydroxyethyl Acrylate/Acryloyldimethyltaurine Na Copolymer, Na Acrylate/Acrylic Acid Dimethyl taurine Na copolymer, polyethylene glycol-240/decyltetradecanol polyether-20/hexamethyldiisocyanate copolymer, hydrophobized hydroxypropyl cellulose, hydroxypropyl starch phosphoric acid at least one of. The oil-in-water emulsified cosmetic according to claim 1 or claim 2, wherein the content of the component (B) is 60% by mass or more relative to the total amount of oil agents contained in the oil-in-water emulsified cosmetic. The oil-in-water emulsified cosmetic according to any one of claim 1 to claim 3, wherein the content of the component (C) is 1 to 20 mass % in the oil-in-water emulsified cosmetic. The oil-in-water emulsified cosmetic according to any one of Claims 1 to 4, wherein the content of the component (D) in the oil-in-water emulsified cosmetic is 0.01% by mass to 0.4% by mass. The oil-in-water emulsified cosmetic according to any one of Claims 1 to 5, wherein nicotinamide and tranexamic acid are used in combination as the (A) component. The oil-in-water emulsified cosmetic according to any one of claim 1 to claim 6, wherein the component (A) to component (C) are contained in a mass ratio (A)/[(B)+(C) ] is 0.05 or more and less than 7. The oil-in-water emulsified cosmetic according to any one of claim 1 to claim 7, wherein the component (A) to component (D) are contained in a mass ratio of [(B)+(C)+(D) ]/(A) is 0.1 or more and 20 or less. The oil-in-water emulsified cosmetic according to any one of Claims 1 to 8, further comprising a component (E) polyglycerol.