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TNSN08190A1 - Pyrazole-isoquinoline urea derivatives as p38 kinase inhibitors - Google Patents

Pyrazole-isoquinoline urea derivatives as p38 kinase inhibitors

Info

Publication number
TNSN08190A1
TNSN08190A1 TNP2008000190A TNSN08190A TNSN08190A1 TN SN08190 A1 TNSN08190 A1 TN SN08190A1 TN P2008000190 A TNP2008000190 A TN P2008000190A TN SN08190 A TNSN08190 A TN SN08190A TN SN08190 A1 TNSN08190 A1 TN SN08190A1
Authority
TN
Tunisia
Prior art keywords
isoquinoline
pyrazole
kinase inhibitors
urea derivatives
inhibitors
Prior art date
Application number
TNP2008000190A
Inventor
Dios Alfonso De
Cristina Garcia-Paredes
De Uralde Garmendia Beatriz Lopez
Mary Margaret Mader
Mark Andrew Pobanz
Chuan Shih
Boyu Zhong
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/US2006/041266 external-priority patent/WO2007053346A1/en
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of TNSN08190A1 publication Critical patent/TNSN08190A1/en

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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

The present invention provides kinase inhibitors of Formula (I) wherein R1, R2, and X are as described herein, or a pharmaceutically acceptable salt thereof. The compounds act as inhibitors of the p38 kinase and are useful for the treatment of conditions resulting from excessive cytokine production
TNP2008000190A 2005-10-28 2008-04-25 Pyrazole-isoquinoline urea derivatives as p38 kinase inhibitors TNSN08190A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP05380240 2005-10-28
PCT/US2006/041266 WO2007053346A1 (en) 2005-10-28 2006-10-23 Pyrazole-isoquinoline urea derivatives as p38 kinase inhibitors

Publications (1)

Publication Number Publication Date
TNSN08190A1 true TNSN08190A1 (en) 2009-10-30

Family

ID=40066544

Family Applications (1)

Application Number Title Priority Date Filing Date
TNP2008000190A TNSN08190A1 (en) 2005-10-28 2008-04-25 Pyrazole-isoquinoline urea derivatives as p38 kinase inhibitors

Country Status (3)

Country Link
CN (1) CN101296924A (en)
TN (1) TNSN08190A1 (en)
ZA (1) ZA200803288B (en)

Also Published As

Publication number Publication date
CN101296924A (en) 2008-10-29
ZA200803288B (en) 2009-09-30

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