TH102899B - A sterile, sterile, aripeprazole formulation for injection with controlled release and method. - Google Patents
A sterile, sterile, aripeprazole formulation for injection with controlled release and method.Info
- Publication number
- TH102899B TH102899B TH401004122A TH0401004122A TH102899B TH 102899 B TH102899 B TH 102899B TH 401004122 A TH401004122 A TH 401004122A TH 0401004122 A TH0401004122 A TH 0401004122A TH 102899 B TH102899 B TH 102899B
- Authority
- TH
- Thailand
- Prior art keywords
- sterile
- formulation
- injection
- aripeprazole
- controlled release
- Prior art date
Links
- 238000013270 controlled release Methods 0.000 title claims abstract 5
- 238000009472 formulation Methods 0.000 title claims abstract 5
- 239000000203 mixture Substances 0.000 title claims abstract 5
- 238000002347 injection Methods 0.000 title claims 3
- 239000007924 injection Substances 0.000 title claims 3
- 238000000034 method Methods 0.000 title abstract 3
- 239000000126 substance Substances 0.000 claims abstract 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract 2
- 239000000725 suspension Substances 0.000 claims 1
- 239000008215 water for injection Substances 0.000 claims 1
- CEUORZQYGODEFX-UHFFFAOYSA-N Aripirazole Chemical compound ClC1=CC=CC(N2CCN(CCCCOC=3C=C4NC(=O)CCC4=CC=3)CC2)=C1Cl CEUORZQYGODEFX-UHFFFAOYSA-N 0.000 abstract 4
- 229960004372 aripiprazole Drugs 0.000 abstract 4
- 239000002245 particle Substances 0.000 abstract 1
- 201000000980 schizophrenia Diseases 0.000 abstract 1
Abstract
ได้มีการให้สูตรผสมของอะริพิพราโซลชนิดแห้งเยือกแข็งแบบปลอดเชื้อที่มีการปลดปล่อย แบบควบคุมซึ่งเตรียมขึ้นจากอะ ริพิพราโซลที่มีขนาดอนุภาคโดยเฉลี่ยตามที่ต้องการกับสื่อ ของสารนี้, ซึ่งเมื่อทำการประกอบขึ้นด้วยน้ำและทำการฉีด เข้าทางกล้ามเนื้อจะปลดปล่อยอะริพิพราโซลตลอด ช่วงเวลาอย่าง น้อยประมาณหนึ่งสัปดาห์และสูงถึงประมาณแปดสัปดาห์ วิธี สำหรับเตรียมสูตรผสม ของอะริพิพราโซลชนิดแห้งเยือกแข็งที่มี การปลดปล่อยแบบควบคุมนี้, และวิธีสำหรับรักษา โรคจิตเภทโดย ใช้สูตรผสมข้างบนนี้ก็ได้ให้ไว้ด้วยเช่นกัน A controlled-release lyophilized aripiprazole formulation prepared from aripiprazole of the desired average particle size and a medium of this substance, when reconstituted with water and injected intramuscularly, releases the aripiprazole over a period of at least approximately one week and up to approximately eight weeks. A method for preparing this controlled-release lyophilized aripiprazole formulation, and a method for treating schizophrenia using the above formulation are also provided.
Claims (3)
Publications (3)
| Publication Number | Publication Date |
|---|---|
| TH102899A TH102899A (en) | 2010-07-30 |
| TH102899B true TH102899B (en) | 2010-07-30 |
| TH56895B TH56895B (en) | 2017-08-22 |
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| TH102899B (en) | A sterile, sterile, aripeprazole formulation for injection with controlled release and method. |