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SV1996000109A - Nueva variante cristalina del cdch, procedimiento para su produccion y preparados farmaceuticos que la contienen ref. lea 31308-sv - Google Patents

Nueva variante cristalina del cdch, procedimiento para su produccion y preparados farmaceuticos que la contienen ref. lea 31308-sv

Info

Publication number
SV1996000109A
SV1996000109A SV1996000109A SV1996000109A SV1996000109A SV 1996000109 A SV1996000109 A SV 1996000109A SV 1996000109 A SV1996000109 A SV 1996000109A SV 1996000109 A SV1996000109 A SV 1996000109A SV 1996000109 A SV1996000109 A SV 1996000109A
Authority
SV
El Salvador
Prior art keywords
cdch
procedure
production
ref
read
Prior art date
Application number
SV1996000109A
Other languages
English (en)
Inventor
Patrick Bosche
Alfons Grunenberg
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=7779831&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SV1996000109(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of SV1996000109A publication Critical patent/SV1996000109A/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

LA INVENCIÓN SE REFIERE AL NUEVO MONOHIDRATO DEL ÁCIDO 1-CICLOPROPIL-7-([S,S]-2,8-DIAZABICICLO[4.3.0]NON-8-IL)-6-FLÚOR-1,4-DIHIDRO-8-METOXI-4-OXO-3-QUINOLINCARBOXÍLICO CLORHIDRATO (CDCH), A UN PROCEDIMIENTO PARA SU PRODUCCIÓN Y A PREPARADOS FARMACÉUTICOS QUE CONTIENEN ESTE MONOHIDRATO COMO SUSTANCIA ACTIVA
SV1996000109A 1995-12-12 1996-12-12 Nueva variante cristalina del cdch, procedimiento para su produccion y preparados farmaceuticos que la contienen ref. lea 31308-sv SV1996000109A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19546249A DE19546249A1 (de) 1995-12-12 1995-12-12 Neue Kristallmodifikation des 1-Cyclopropyl-7-([S,S]-2,8-diazabicyclo[4,3,0]non-8-yl)-6-fluor-1,4-dihydro-8-methoxy-4-oxo-3-chinolincarbonsäure Hydrochlorid (CDCH), Verfahren zu dessen Herstellung und diese enthaltende pharmazeutische Zubereitungen

Publications (1)

Publication Number Publication Date
SV1996000109A true SV1996000109A (es) 1997-10-23

Family

ID=7779831

Family Applications (1)

Application Number Title Priority Date Filing Date
SV1996000109A SV1996000109A (es) 1995-12-12 1996-12-12 Nueva variante cristalina del cdch, procedimiento para su produccion y preparados farmaceuticos que la contienen ref. lea 31308-sv

Country Status (42)

Country Link
US (1) US5849752A (es)
EP (1) EP0780390B1 (es)
JP (1) JP4104687B2 (es)
KR (1) KR100525146B1 (es)
CN (1) CN1061348C (es)
AR (1) AR005009A1 (es)
AT (1) ATE221531T1 (es)
AU (1) AU708006B2 (es)
BG (1) BG62258B1 (es)
BR (1) BR9605968A (es)
CA (1) CA2192418C (es)
CO (1) CO4480105A1 (es)
CU (1) CU22774A3 (es)
CZ (1) CZ288657B6 (es)
DE (2) DE19546249A1 (es)
DK (1) DK0780390T3 (es)
EE (1) EE03474B1 (es)
ES (1) ES2179910T3 (es)
HR (1) HRP960558B1 (es)
HU (1) HU226521B1 (es)
ID (1) ID22625A (es)
IL (1) IL119795A (es)
IN (1) IN185805B (es)
MA (1) MA24342A1 (es)
MY (1) MY117492A (es)
NL (1) NL300109I1 (es)
NO (1) NO306725B1 (es)
NZ (1) NZ299905A (es)
PL (1) PL184885B1 (es)
PT (1) PT780390E (es)
RO (1) RO119782B1 (es)
RU (1) RU2162468C2 (es)
SA (1) SA96170492B1 (es)
SG (1) SG47201A1 (es)
SI (1) SI0780390T1 (es)
SK (1) SK282805B6 (es)
SV (1) SV1996000109A (es)
TR (1) TR199600970A2 (es)
TW (1) TW411340B (es)
UA (1) UA35638C2 (es)
YU (1) YU49485B (es)
ZA (1) ZA9610405B (es)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL192273B1 (pl) * 1997-09-25 2006-09-29 Bayer Ag Preparat środka leczniczego w postaci pastylki o kontrolowanej dyfuzji lub w postaci układu matrycowego, o kontrolowanym uwalnianiu substancji czynnej
DE19751948A1 (de) * 1997-11-24 1999-05-27 Bayer Ag Verfahren zur Herstellung von 8-Methoxy-Chinoloncarbonsäuren
US6716830B2 (en) 1998-09-30 2004-04-06 Alcon, Inc. Ophthalmic antibiotic compositions containing moxifloxacin
US6395746B1 (en) 1998-09-30 2002-05-28 Alcon Manufacturing, Ltd. Methods of treating ophthalmic, otic and nasal infections and attendant inflammation
US6509327B1 (en) 1998-09-30 2003-01-21 Alcon Manufacturing, Ltd. Compositions and methods for treating otic, ophthalmic and nasal infections
CA2349161C (en) * 1998-11-10 2008-01-29 Bayer Aktiengesellschaft Pharmaceutical moxifloxacin preparation
DE19854357A1 (de) * 1998-11-25 2000-05-31 Bayer Ag Semi-Hydrochlorid von 8-Cyan-1-cyclopropyl-7-(1S,6S-2,8-diazabicyclo/4.3.0/ -nonan-8-yl)-6-fluor-1,4-dihydro-4-oxo-3-chinolincarbonsäure
DE19854355A1 (de) * 1998-11-25 2000-05-31 Bayer Ag Kristallmodifikation B von 8-Cyan-1-cyclopropyl-7-(1S, 6S-2,8-diazabicyclo-/4.3.O/nonan-8-yl)-6-fluor-1,4-dihydro-4-oxo-3-chinolincarbonsäure
DE19854356A1 (de) * 1998-11-25 2000-05-31 Bayer Ag Kristallmodifikation A von 8-Cyan-1-cyclopropyl-7-(1S,6S-2,8-diazabicyclo-/4.3.0/nonan-8-yl)-6-fluor-1,4-dihydro-4-oxo-3-chinolincarbonsäure
DE19908449A1 (de) 1999-02-26 2000-08-31 Bayer Ag Kristallmodifikation C von 8-Cyan-1-cyclopropyl-7-(1S,6S-2,8-diazabicylo-[4.3.0]nonan-8-yl)-6-fluor-1,4-dihydro-4-oxo-3-chino/incarbonsäure
EP1562942A1 (en) * 2002-10-31 2005-08-17 Ranbaxy Laboratories, Ltd. Amorphous moxifloxacin hydrochloride
EP2113505A1 (en) 2003-04-09 2009-11-04 Dr. Reddy's Laboratories, Ltd. A crystalline form III of anhydrous moxifloxacin hydrochloride and processes for the preparation thereof
WO2005012285A1 (en) * 2003-08-05 2005-02-10 Matrix Laboratories Ltd An improved process for the preparation of moxifloxacin hydrochloride
WO2005054240A1 (en) * 2003-11-20 2005-06-16 Chemi Spa Polymorphs of 1-cyclopropyl-7-([s,s]-2,8-diazadicyclo[4.3.0]non-8-yl)-6-fluoro-1,4-dihydro-8-methoxy-4-oxo-3-quinoline carboxylic acid hydrochloride and methods for the preparation thereof
ITMI20032259A1 (it) 2003-11-20 2005-05-21 Chemi Spa Nuovo polimorfo dell'acido 1-ciclopropil-7-(s,s-2,8-diazabciclo-4.3.0-non-8-il)-6-fluoro-1,4-diidro-8-metossi-4-oxo-chinolin carbossilico cloridrato e metodi per la sua preparazione
US7491725B2 (en) 2004-02-06 2009-02-17 Bristol-Myers Squibb Company Process for preparing 2-aminothiazole-5-aromatic carboxamides as kinase inhibitors
DE102004063347A1 (de) * 2004-12-23 2006-07-13 Stada Arzneimittel Ag Gebrauchsfertige Gemcitabinlösungen und Gemcitabinlösungskonzentrate
WO2007033515A1 (fr) * 2005-09-21 2007-03-29 Shenzhen Tys R & D Co., Ltd. Formulation orale contenant de la moxifloxacine et son procédé de préparation
GB0612422D0 (en) * 2006-06-23 2006-08-02 Generics Uk Ltd Novel hydrate form
PL2032521T3 (pl) 2006-06-27 2010-05-31 Sandoz Ag Nowy sposób wytwarzania soli
ES2303768B1 (es) * 2006-09-08 2009-06-05 Quimica Sintetica, S.A. Nueva forma cristalina de moxifloxacino clorhidrato.
KR101539561B1 (ko) * 2006-11-13 2015-07-27 씨아이피엘에이 엘티디. 목시플록사신 염산염의 합성방법
EP1992626A1 (en) * 2007-05-10 2008-11-19 Sandoz AG Process for the preparation of moxifloxacin hydrochloride
EP2083010A1 (en) * 2008-01-08 2009-07-29 Chemo Ibérica, S.A. Polymorphic Forms of Moxifloxacin hydrochloride and processes for preparation thereof
EP2154137A1 (en) 2008-08-04 2010-02-17 Chemo Ibérica, S.A. Crystalline form of moxifloxacin base
MX2011003731A (es) 2008-10-09 2011-08-03 Abdi Ibrahim Ilac Sanayi Ve Ticaret Anonim Sirketi Uso de solventes organicos en la granulacion humeda de moxifloxacino.
US20110212990A1 (en) * 2008-11-06 2011-09-01 Hetero Research Foundation Novel polymorph of moxifloxacin hydrochloride
ES2467105T5 (es) 2008-12-08 2017-12-05 Ratiopharm Gmbh Moxifloxacino compactado
US8877945B2 (en) 2009-05-15 2014-11-04 Redx Pharma Limited Redox drug derivatives
WO2011121596A2 (en) * 2010-04-01 2011-10-06 Neuland Laboratories Ltd. Crystal modification of moxifloxacin hydrochloride
BRPI1106900A2 (pt) 2011-12-26 2013-11-05 Ems Sa Composição farmacêutica sólida compreendendo antibótico da familia das quinolonas e processo de sua obtenção
FR2992218B1 (fr) 2012-06-22 2015-01-23 Rivopharm Sa Composition pharmaceutique de chlorhydrate de moxifloxacine et procede de preparation
CN102924449B (zh) * 2012-10-30 2015-08-12 重庆福安药业集团庆余堂制药有限公司 盐酸莫西沙星h晶型及其制备方法和药物组合物
EP2928892B1 (en) 2012-12-04 2018-03-21 Mankind Pharma Ltd. An improved process for the preparation of moxifloxacin hydrochloride
RU2561037C2 (ru) * 2013-02-07 2015-08-20 Открытое акционерное общество "Химико-фармацевтический комбинат "АКРИХИН" (ОАО "АКРИХИН") Антибактериальная фармацевтическая композиция и способ ее получения
JP6617097B2 (ja) 2013-03-15 2019-12-04 メリンタ サブシディアリー コーポレーション 抗生物質を用いて過体重および肥満の患者における感染を治療するための組成物

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3601567A1 (de) * 1986-01-21 1987-07-23 Bayer Ag 7-(azabicycloalkyl)-chinoloncarbonsaeure- und -naphthyridon-carbonsaeure-derivate
FI871419A (fi) * 1986-03-31 1987-10-01 Sankyo Co Kinolin-3-karboxylsyraderivat, deras framstaellning och anvaendning.
AU609974B2 (en) * 1988-05-18 1991-05-09 Warner-Lambert Company Improved process for the preparation of 5-amino-7- (substituted amino)-quinoline-3-carboxylic acids
DE3910663A1 (de) * 1989-04-03 1990-10-04 Bayer Ag 5-alkylchinoloncarbonsaeuren
TW209865B (es) 1992-01-10 1993-07-21 Bayer Ag
EP0629621B1 (en) * 1992-01-31 2001-10-24 Chugai Seiyaku Kabushiki Kaisha Crystal of quinolonecarboxylic acid derivative hydrate
DE4234078A1 (de) 1992-10-09 1994-04-14 Bayer Ag Chinoloncarbonsäuren
CA2112165C (en) * 1992-12-25 2003-04-08 Makoto Takemura Bicyclic amine derivatives
ZA946853B (en) * 1993-09-10 1995-04-24 Daiichi Seiyaku Co Crystals of antimicrobial compound.
ES2121293T3 (es) * 1994-04-07 1998-11-16 Pfizer Uso de trovafloxacina o derivados de la misma para la fabricacion de un medicamento para el tratamiento de infecciones por h. pylori.

Also Published As

Publication number Publication date
SA96170492B1 (ar) 2006-05-23
IL119795A0 (en) 1997-03-18
TW411340B (en) 2000-11-11
PL317415A1 (en) 1997-06-23
US5849752A (en) 1998-12-15
CU22774A3 (es) 2002-07-24
AU7421696A (en) 1997-06-19
SI0780390T1 (en) 2002-10-31
SG47201A1 (en) 1998-03-20
UA35638C2 (uk) 2001-04-16
MA24342A1 (fr) 1998-07-01
KR100525146B1 (ko) 2006-01-27
ATE221531T1 (de) 2002-08-15
AU708006B2 (en) 1999-07-29
EP0780390B1 (de) 2002-07-31
HRP960558A2 (en) 1998-02-28
CA2192418C (en) 2001-06-12
YU49485B (sh) 2006-08-17
AR005009A1 (es) 1999-04-07
NZ299905A (en) 1998-09-24
ZA9610405B (en) 1997-06-23
CA2192418A1 (en) 1997-06-13
JP4104687B2 (ja) 2008-06-18
DK0780390T3 (da) 2002-11-11
IN185805B (es) 2001-05-05
NO965298D0 (no) 1996-12-11
ES2179910T3 (es) 2003-02-01
BG62258B1 (bg) 1999-06-30
DE19546249A1 (de) 1997-06-19
SK159196A3 (en) 1997-10-08
KR970042550A (ko) 1997-07-24
PL184885B1 (pl) 2003-01-31
DE59609501D1 (de) 2002-09-05
TR199600970A2 (tr) 1997-06-21
HU226521B1 (en) 2009-03-30
CN1061348C (zh) 2001-01-31
NL300109I1 (nl) 2003-02-03
MY117492A (en) 2004-07-31
CZ288657B6 (cs) 2001-08-15
EE03474B1 (et) 2001-08-15
NO965298L (no) 1997-06-13
SK282805B6 (sk) 2002-12-03
CN1160052A (zh) 1997-09-24
CZ364696A3 (en) 1997-07-16
EP0780390A1 (de) 1997-06-25
HU9603428D0 (en) 1997-01-28
NO306725B1 (no) 1999-12-13
HUP9603428A2 (en) 1997-08-28
BG101043A (en) 1998-04-30
JPH09169757A (ja) 1997-06-30
IL119795A (en) 1998-12-27
EE9600201A (et) 1997-06-16
HUP9603428A3 (en) 1997-10-28
ID22625A (id) 1999-12-02
HRP960558B1 (en) 2002-04-30
RU2162468C2 (ru) 2001-01-27
CO4480105A1 (es) 1997-07-09
BR9605968A (pt) 1998-08-18
RO119782B1 (ro) 2005-03-30
MX9606325A (es) 1997-10-31
YU65096A (sh) 1998-12-23
PT780390E (pt) 2002-11-29

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