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SU1181541A3 - "cпocoб пoлучehия -зameщehhыx пpoизboдhыx aзиpидиh-2-kapбohoboй kиcлotы или иx coлeй" - Google Patents

"cпocoб пoлучehия -зameщehhыx пpoизboдhыx aзиpидиh-2-kapбohoboй kиcлotы или иx coлeй"

Info

Publication number
SU1181541A3
SU1181541A3 SU802882348A SU2882348A SU1181541A3 SU 1181541 A3 SU1181541 A3 SU 1181541A3 SU 802882348 A SU802882348 A SU 802882348A SU 2882348 A SU2882348 A SU 2882348A SU 1181541 A3 SU1181541 A3 SU 1181541A3
Authority
SU
USSR - Soviet Union
Prior art keywords
ethyleneimine
salts
producing
carboxylic acid
substituted derivatives
Prior art date
Application number
SU802882348A
Other languages
English (en)
Inventor
Elmar Bozies
Volfgang Kampe
Maks Til
Uve Biker
Ditmar Boerner
Original Assignee
Boehringer Mannheim Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Mannheim Gmbh filed Critical Boehringer Mannheim Gmbh
Application granted granted Critical
Publication of SU1181541A3 publication Critical patent/SU1181541A3/ru

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D203/00—Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D203/04—Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D203/06—Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D203/22—Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms directly attached to the ring nitrogen atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Transplantation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
SU802882348A 1979-02-21 1980-02-18 "cпocoб пoлучehия -зameщehhыx пpoизboдhыx aзиpидиh-2-kapбohoboй kиcлotы или иx coлeй" SU1181541A3 (ru)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19792906603 DE2906603A1 (de) 1979-02-21 1979-02-21 N-substituierte aziridin-2-carbonsaeurederivate, verfahren zu deren herstellung sowie diese substanzen enthaltende arzneimittel

Publications (1)

Publication Number Publication Date
SU1181541A3 true SU1181541A3 (ru) 1985-09-23

Family

ID=6063481

Family Applications (1)

Application Number Title Priority Date Filing Date
SU802882348A SU1181541A3 (ru) 1979-02-21 1980-02-18 "cпocoб пoлучehия -зameщehhыx пpoизboдhыx aзиpидиh-2-kapбohoboй kиcлotы или иx coлeй"

Country Status (19)

Country Link
US (2) US4397848A (ru)
EP (1) EP0014976B1 (ru)
JP (1) JPS55113760A (ru)
AR (1) AR223863A1 (ru)
AT (1) ATE818T1 (ru)
AU (1) AU529982B2 (ru)
CA (1) CA1148962A (ru)
CS (1) CS208798B2 (ru)
DD (1) DD148772A5 (ru)
DE (2) DE2906603A1 (ru)
ES (1) ES488656A1 (ru)
FI (1) FI70702C (ru)
HU (1) HU182801B (ru)
IE (1) IE49267B1 (ru)
IL (1) IL59425A (ru)
PL (1) PL129707B1 (ru)
PT (1) PT70847A (ru)
SU (1) SU1181541A3 (ru)
ZA (1) ZA80902B (ru)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4925835A (en) * 1986-05-01 1990-05-15 Sloan-Kettering Institute For Cancer Research Aziridinyl putrescine containing compositions and their uses in treating prostate cancer
JPH07301287A (ja) * 1995-03-23 1995-11-14 Sumitomo Heavy Ind Ltd 制御装置に用いられる内接噛合遊星歯車機構
WO1999000120A1 (en) * 1997-06-27 1999-01-07 Arizona Board Of Regents, University Of Arizona Novel cyanoaziridines for treating cancer
US20030129222A1 (en) * 2000-11-21 2003-07-10 Gabriel Lopez-Berestein Liposomal imexon
CA2431947A1 (en) * 2000-11-21 2002-05-30 Gabriel Lopez-Berestein Composition comprising an imexon or derivatives thereof and lipids
US7011846B2 (en) * 2001-12-21 2006-03-14 Shire Laboratories, Inc. Oral capsule formulation with increased physical stability
US20040005339A1 (en) * 2002-06-28 2004-01-08 Shojaei Amir H. Formulations of fenofibrate and/or fenofibrate derivatives with improved oral bioavailability
PT1599468E (pt) 2003-01-14 2008-01-14 Arena Pharm Inc Derivados de arilo e heteroarilo 1,2,3.-trissubstituídos comomoduladores do metabolismo, e profilaxia e tratamento dedesordens relacionadas tais como diabetes e hiperglicemia
CA2515963A1 (en) * 2003-02-24 2004-09-10 Arena Pharmaceuticals, Inc. Phenyl- and pyridylpiperidine-derivatives as modulators of glucose metabolism
AR045047A1 (es) 2003-07-11 2005-10-12 Arena Pharm Inc Derivados arilo y heteroarilo trisustituidos como moduladores del metabolismo y de la profilaxis y tratamiento de desordenes relacionados con los mismos
WO2005121121A2 (en) * 2004-06-04 2005-12-22 Arena Pharmaceuticals, Inc. Substituted aryl and heteroaryl derivatives as modulators of metabolism and the prophylaxis and treatment of disorders related thereto
DOP2006000010A (es) 2005-01-10 2006-07-31 Arena Pharm Inc Procedimiento para preparar eteres aromáticos
MY148521A (en) * 2005-01-10 2013-04-30 Arena Pharm Inc Substituted pyridinyl and pyrimidinyl derivatives as modulators of metabolism and the treatment of disorders related thereto
US20100160359A1 (en) * 2005-09-16 2010-06-24 Arena Pharmaceuticals, Inc. Modulators of Metabolism and the Treatment of Disorders Related Thereto
TW200811147A (en) * 2006-07-06 2008-03-01 Arena Pharm Inc Modulators of metabolism and the treatment of disorders related thereto
TW200811140A (en) * 2006-07-06 2008-03-01 Arena Pharm Inc Modulators of metabolism and the treatment of disorders related thereto
EP4148045A1 (en) 2010-01-27 2023-03-15 Arena Pharmaceuticals, Inc. Intermediate compounds for the preparation of (r)-2-(7-(4-cyclopentyl-3- (trifluoromethyl)benzyloxy)-1,2,3,4-tetrahydrocyclopenta[b] indol-3-yl)acetic acid and salts thereof
BR112013008100A2 (pt) 2010-09-22 2016-08-09 Arena Pharm Inc "moduladores do receptor de gpr19 e o tratamento de distúrbios relacionados a eles."
AU2016205361C1 (en) 2015-01-06 2021-04-08 Arena Pharmaceuticals, Inc. Methods of treating conditions related to the S1P1 receptor
CN108349891B (zh) 2015-06-22 2022-04-05 艾尼纳制药公司 用于s1p1受体相关病症的化合物的结晶l-精氨酸盐
AU2018220521A1 (en) 2017-02-16 2019-09-05 Arena Pharmaceuticals, Inc. Compounds and methods for treatment of primary biliary cholangitis
CN113816887A (zh) * 2021-08-31 2021-12-21 华中科技大学 一种氮杂环丙烷类化合物及其制备方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2644820A1 (de) * 1976-10-05 1978-04-06 Boehringer Mannheim Gmbh Cancerostatisch und immunstimulierend wirkende 1-(n-acyl-carbamoyl)-2-cyanaziridine sowie verfahren zur herstellung derselben
DE2731264A1 (de) 1977-07-11 1979-02-01 Boehringer Mannheim Gmbh Neue 1-acyl-2-cyanaziridine, verfahren zu deren herstellung und diese verbindungen enthaltende pharmazeutische zubereitungen

Also Published As

Publication number Publication date
FI70702B (fi) 1986-06-26
DE3060268D1 (en) 1982-05-19
DE2906603A1 (de) 1980-09-04
JPH0150700B2 (ru) 1989-10-31
AU5564980A (en) 1980-08-28
EP0014976B1 (de) 1982-04-07
FI800510A (fi) 1980-08-22
US4397848A (en) 1983-08-09
ES488656A1 (es) 1980-09-16
ZA80902B (en) 1981-03-25
PL129707B1 (en) 1984-06-30
US4517183A (en) 1985-05-14
ATE818T1 (de) 1982-04-15
PL222088A1 (ru) 1980-12-01
IE49267B1 (en) 1985-09-04
HU182801B (en) 1984-03-28
FI70702C (fi) 1986-10-06
EP0014976A1 (de) 1980-09-03
IE800327L (en) 1980-08-21
PT70847A (de) 1980-03-01
CS208798B2 (en) 1981-09-15
IL59425A0 (en) 1980-05-30
DD148772A5 (de) 1981-06-10
AU529982B2 (en) 1983-06-30
JPS55113760A (en) 1980-09-02
AR223863A1 (es) 1981-09-30
IL59425A (en) 1984-05-31
CA1148962A (en) 1983-06-28

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