SK11562003A3 - Nové spirotricyklické deriváty a ich použitie ako inhibítorov fosfodiesterázy-7 - Google Patents

Nové spirotricyklické deriváty a ich použitie ako inhibítorov fosfodiesterázy-7 Download PDF

Info

Publication number: SK11562003A3
Authority: SK; Slovakia
Prior art keywords: dihydro; cyclohexane; lower alkyl; chloro; quinazolin
Prior art date: 2001-03-21

Application number

SK1156-2003A

Other languages

English (en)

Slovak (sk)

Inventor

Patrick Bernardelli

Pierre Ducrot

Edwige Lorthiois

Fabrice Vergne

Original Assignee

Warner-Lambert Company Llc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2001-03-21

Filing date

2002-03-18

Publication date

2005-01-03

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=8164349&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SK11562003(A3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2002-03-18 Application filed by Warner-Lambert Company Llc filed Critical Warner-Lambert Company Llc

2005-01-03 Publication of SK11562003A3 publication Critical patent/SK11562003A3/sk

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
- C07D239/72—Quinazolines; Hydrogenated quinazolines
- C07D239/78—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 2
- C07D239/80—Oxygen atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Immunology (AREA)
Physical Education & Sports Medicine (AREA)
Rheumatology (AREA)
Pulmonology (AREA)
Oncology (AREA)
Virology (AREA)
Orthopedic Medicine & Surgery (AREA)
Communicable Diseases (AREA)
Pain & Pain Management (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Biomedical Technology (AREA)
Molecular Biology (AREA)
Tropical Medicine & Parasitology (AREA)
AIDS & HIV (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Plural Heterocyclic Compounds (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)

SK1156-2003A 2001-03-21 2002-03-18 Nové spirotricyklické deriváty a ich použitie ako inhibítorov fosfodiesterázy-7 SK11562003A3 (sk)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
PCT/EP2001/003355 WO2002076953A1 (fr)	2001-03-21	2001-03-21	Nouveaux derives spirotricycliques et utilisation de ces derives en tant qu'inhibiteurs de la phosphodiesterase-7
PCT/EP2002/003594 WO2002074754A1 (fr)	2001-03-21	2002-03-18	Nouveaux derives spirotricycliques et leur utilisation en tant qu'inhibiteurs de la phosphodiesterase-7

Publications (1)

Publication Number	Publication Date
SK11562003A3 true SK11562003A3 (sk)	2005-01-03

Family

ID=8164349

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
SK1156-2003A SK11562003A3 (sk)	2001-03-21	2002-03-18	Nové spirotricyklické deriváty a ich použitie ako inhibítorov fosfodiesterázy-7

Country Status (47)

Country	Link
US (3)	US20020198198A1 (fr)
EP (2)	EP1801106A3 (fr)
JP (1)	JP4086663B2 (fr)
KR (1)	KR100617435B1 (fr)
CN (1)	CN100447136C (fr)
AP (1)	AP1699A (fr)
AR (1)	AR033617A1 (fr)
AT (1)	ATE367381T1 (fr)
AU (1)	AU2002304800B2 (fr)
BG (1)	BG108181A (fr)
BR (1)	BR0208192A (fr)
CA (1)	CA2441313C (fr)
CU (1)	CU23218A3 (fr)
CY (1)	CY1106829T1 (fr)
CZ (1)	CZ20032451A3 (fr)
DE (1)	DE60221233T2 (fr)
DK (1)	DK1373224T3 (fr)
EA (1)	EA006815B1 (fr)
EC (1)	ECSP034750A (fr)
EE (1)	EE200300459A (fr)
ES (1)	ES2288552T3 (fr)
GE (1)	GEP20053631B (fr)
GT (1)	GT200200053A (fr)
HK (1)	HK1061854A1 (fr)
HR (1)	HRP20030740A2 (fr)
HU (1)	HUP0303637A3 (fr)
IL (2)	IL157659A0 (fr)
IS (1)	IS2529B (fr)
MA (1)	MA27001A1 (fr)
MX (1)	MXPA03008485A (fr)
MY (1)	MY142045A (fr)
NO (1)	NO326086B1 (fr)
NZ (1)	NZ527847A (fr)
OA (1)	OA12454A (fr)
PA (1)	PA8541601A1 (fr)
PE (1)	PE20021010A1 (fr)
PL (1)	PL367058A1 (fr)
PT (1)	PT1373224E (fr)
RS (1)	RS50429B (fr)
SI (1)	SI1373224T1 (fr)
SK (1)	SK11562003A3 (fr)
SV (1)	SV2003000925A (fr)
TN (1)	TNSN03076A1 (fr)
TW (1)	TWI267509B (fr)
UA (1)	UA74243C2 (fr)
WO (2)	WO2002076953A1 (fr)
ZA (1)	ZA200306601B (fr)

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EP2617419A1 (fr)	2003-04-24	2013-07-24	Incyte Corporation	Dérivés d'aza-spiro-alcanes utilisés comme inhibiteurs de métalloprotéases
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US20100184806A1 (en)	2006-09-19	2010-07-22	Braincells, Inc.	Modulation of neurogenesis by ppar agents
CN101917992A (zh) *	2007-03-27	2010-12-15	奥默罗斯公司	用于治疗运动障碍的pde7抑制剂的用途
US8637528B2 (en)	2007-03-27	2014-01-28	Omeros Corporation	Use of PDE7 inhibitors for the treatment of movement disorders
CA2687944A1 (fr) *	2007-05-24	2008-11-27	Pfizer Limited	Derives spirocycliques
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CN107375296A (zh)	2010-11-08	2017-11-24	奥默罗斯公司	使用pde7抑制剂治疗成瘾和冲动控制障碍
US9220715B2 (en)	2010-11-08	2015-12-29	Omeros Corporation	Treatment of addiction and impulse-control disorders using PDE7 inhibitors
WO2012088266A2 (fr)	2010-12-22	2012-06-28	Incyte Corporation	Imidazopyridazines et benzimidazoles substitués en tant qu'inhibiteurs de fgfr3
US20150119399A1 (en)	2012-01-10	2015-04-30	President And Fellows Of Harvard College	Beta-cell replication promoting compounds and methods of their use
NZ702747A (en)	2012-06-13	2017-03-31	Incyte Holdings Corp	Substituted tricyclic compounds as fgfr inhibitors
WO2014026125A1 (fr)	2012-08-10	2014-02-13	Incyte Corporation	Dérivés de pyrazine en tant qu'inhibiteurs de fgfr
US9266892B2 (en)	2012-12-19	2016-02-23	Incyte Holdings Corporation	Fused pyrazoles as FGFR inhibitors
EP2986610B9 (fr)	2013-04-19	2018-10-17	Incyte Holdings Corporation	Hétérocycles bicycliques utilisés en tant qu'inhibiteurs de fgfr
US10851105B2 (en)	2014-10-22	2020-12-01	Incyte Corporation	Bicyclic heterocycles as FGFR4 inhibitors
MA41551A (fr)	2015-02-20	2017-12-26	Incyte Corp	Hétérocycles bicycliques utilisés en tant qu'inhibiteurs de fgfr4
WO2016134294A1 (fr)	2015-02-20	2016-08-25	Incyte Corporation	Hétérocycles bicycliques utilisés en tant qu'inhibiteurs de fgfr4
US9708318B2 (en)	2015-02-20	2017-07-18	Incyte Corporation	Bicyclic heterocycles as FGFR4 inhibitors
CA3008689A1 (fr) *	2015-12-16	2017-06-22	Chia Tai Tianqing Pharmaceutical Group Co., Ltd.	Analogue de pyrido[1,2-a]pyrimidone, sa forme cristalline, son intermediaire et son procede de preparation
AR111960A1 (es)	2017-05-26	2019-09-04	Incyte Corp	Formas cristalinas de un inhibidor de fgfr y procesos para su preparación
CN107382976A (zh) *	2017-07-04	2017-11-24	孙秀芹	一种治疗盆腔炎的化合物及制备方法和应用
MX2020000295A (es) *	2017-07-12	2020-07-22	Dart Neuroscience Llc	Compuestos de benzoxazol y benzofurano sustituidos como inhibidores de pde7.
CR20200591A (es)	2018-05-04	2021-03-31	Incyte Corp	Sales de un inhibidor de fgfr
IL312465A (en)	2018-05-04	2024-06-01	Incyte Corp	FGFR inhibitor solid forms and processes for their preparation
WO2020185532A1 (fr)	2019-03-08	2020-09-17	Incyte Corporation	Méthodes de traitement du cancer au moyen d'un inhibiteur de fgfr
US11591329B2 (en)	2019-07-09	2023-02-28	Incyte Corporation	Bicyclic heterocycles as FGFR inhibitors
US12122767B2 (en)	2019-10-01	2024-10-22	Incyte Corporation	Bicyclic heterocycles as FGFR inhibitors
TW202128685A (zh)	2019-10-14	2021-08-01	美商英塞特公司	作為ｆｇｆｒ抑制劑之雙環雜環
WO2021076728A1 (fr)	2019-10-16	2021-04-22	Incyte Corporation	Hétérocycles bicycliques en tant qu'inhibiteurs de fgfr
EP4069696A1 (fr)	2019-12-04	2022-10-12	Incyte Corporation	Hétérocycles tricycliques en tant qu'inhibiteurs de fgfr
US11407750B2 (en)	2019-12-04	2022-08-09	Incyte Corporation	Derivatives of an FGFR inhibitor
WO2021146424A1 (fr)	2020-01-15	2021-07-22	Incyte Corporation	Hétérocycles bicycliques en tant qu'inhibiteurs de fgfr
JP2024513575A (ja)	2021-04-12	2024-03-26	インサイト・コーポレイション	Ｆｇｆｒ阻害剤及びネクチン－４標的化剤を含む併用療法
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Also Published As

Publication number	Publication date
IS2529B (is)	2009-07-15
HUP0303637A3 (en)	2004-07-28
AP1699A (en)	2006-12-26
US20070049558A1 (en)	2007-03-01
NO20034187L (no)	2003-10-15
HUP0303637A2 (hu)	2004-03-01
CN100447136C (zh)	2008-12-31
OA12454A (en)	2004-09-30
DK1373224T3 (da)	2007-10-15
CU23218A3 (es)	2007-07-20
RS50429B (sr)	2009-12-31
PE20021010A1 (es)	2003-02-01
PL367058A1 (en)	2005-02-21
CZ20032451A3 (cs)	2004-09-15
CY1106829T1 (el)	2012-05-23
TNSN03076A1 (fr)	2005-12-23
NO326086B1 (no)	2008-09-15
GT200200053A (es)	2003-02-12
HK1061854A1 (en)	2004-10-08
EA006815B1 (ru)	2006-04-28
JP4086663B2 (ja)	2008-05-14
MY142045A (en)	2010-08-30
KR20030086315A (ko)	2003-11-07
US20020198198A1 (en)	2002-12-26
AU2002304800B2 (en)	2007-08-30
ZA200306601B (en)	2004-08-25
EA200300906A1 (ru)	2004-02-26
CA2441313A1 (fr)	2002-09-26
CN1498212A (zh)	2004-05-19
CA2441313C (fr)	2009-03-31
YU74003A (sh)	2006-05-25
MA27001A1 (fr)	2004-12-20
WO2002074754A1 (fr)	2002-09-26
ES2288552T3 (es)	2008-01-16
UA74243C2 (uk)	2005-11-15
EP1373224B1 (fr)	2007-07-18
US20040214843A1 (en)	2004-10-28
ATE367381T1 (de)	2007-08-15
BG108181A (en)	2004-09-30
NO20034187D0 (no)	2003-09-19
DE60221233T2 (de)	2008-04-03
JP2004529123A (ja)	2004-09-24
HRP20030740A2 (en)	2005-06-30
IS6934A (is)	2003-08-29
TWI267509B (en)	2006-12-01
SV2003000925A (es)	2003-05-20
MXPA03008485A (es)	2003-12-08
US7214676B2 (en)	2007-05-08
EP1801106A3 (fr)	2007-07-04
PA8541601A1 (es)	2003-05-14
IL157659A (en)	2008-08-07
DE60221233D1 (de)	2007-08-30
EP1801106A2 (fr)	2007-06-27
AP2003002857A0 (en)	2003-09-30
EP1373224A1 (fr)	2004-01-02
WO2002076953A1 (fr)	2002-10-03
SI1373224T1 (sl)	2007-10-31
KR100617435B1 (ko)	2006-08-31
AR033617A1 (es)	2003-12-26
PT1373224E (pt)	2007-09-25
BR0208192A (pt)	2004-03-02
GEP20053631B (en)	2005-10-10
IL157659A0 (en)	2004-03-28
EE200300459A (et)	2004-02-16
ECSP034750A (es)	2003-10-28
NZ527847A (en)	2005-06-24

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