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SI2890777T1 - Farmacevtski sestavek, ki obsega pCMV-VEGF165, za stimulacijo angiogeneze - Google Patents

Farmacevtski sestavek, ki obsega pCMV-VEGF165, za stimulacijo angiogeneze

Info

Publication number
SI2890777T1
SI2890777T1 SI201330595A SI201330595A SI2890777T1 SI 2890777 T1 SI2890777 T1 SI 2890777T1 SI 201330595 A SI201330595 A SI 201330595A SI 201330595 A SI201330595 A SI 201330595A SI 2890777 T1 SI2890777 T1 SI 2890777T1
Authority
SI
Slovenia
Prior art keywords
vegf165
pcmv
angiogenesis
stimulation
pharmaceutical composition
Prior art date
Application number
SI201330595A
Other languages
English (en)
Inventor
Sergej L'vovich Kiselev
Roman Vadimovich Deev
Ivan Ivanovich Vorob'ev
Nadezhda Aleksandrovna Orlova
Artur Aleksandrovich Isaev
Original Assignee
"Nextgen" Company Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by "Nextgen" Company Limited filed Critical "Nextgen" Company Limited
Publication of SI2890777T1 publication Critical patent/SI2890777T1/sl

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18Growth factors; Growth regulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18Growth factors; Growth regulators
    • A61K38/1858Platelet-derived growth factor [PDGF]
    • A61K38/1866Vascular endothelial growth factor [VEGF]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475Growth factors; Growth regulators
    • C07K14/515Angiogenesic factors; Angiogenin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Vascular Medicine (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Genetics & Genomics (AREA)
  • Toxicology (AREA)
  • Biophysics (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
SI201330595A 2012-08-31 2013-08-02 Farmacevtski sestavek, ki obsega pCMV-VEGF165, za stimulacijo angiogeneze SI2890777T1 (sl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
RU2012137126/10A RU2542385C2 (ru) 2012-08-31 2012-08-31 Способ получения фармацевтической композиции для индукции развития кровеносных сосудов в тканях, фармацевтическая композиция, полученная этим способом, и способ лечения ишемии тканей и/или органов человека
PCT/RU2013/000669 WO2014035289A1 (en) 2012-08-31 2013-08-02 A pharmaceutical composition for stimulation of angiogenesis
EP13832746.5A EP2890777B1 (en) 2012-08-31 2013-08-02 A pharmaceutical composition comprising pcmv-vegf165 for stimulation of angiogenesis

Publications (1)

Publication Number Publication Date
SI2890777T1 true SI2890777T1 (sl) 2017-06-30

Family

ID=50183970

Family Applications (1)

Application Number Title Priority Date Filing Date
SI201330595A SI2890777T1 (sl) 2012-08-31 2013-08-02 Farmacevtski sestavek, ki obsega pCMV-VEGF165, za stimulacijo angiogeneze

Country Status (13)

Country Link
US (1) US9616103B2 (sl)
EP (1) EP2890777B1 (sl)
CN (1) CN105308173B (sl)
BR (1) BR112015002522B1 (sl)
CA (1) CA2881799C (sl)
ES (1) ES2621675T3 (sl)
HU (1) HUE032520T2 (sl)
MX (1) MX360980B (sl)
PL (1) PL2890777T3 (sl)
RU (1) RU2542385C2 (sl)
SI (1) SI2890777T1 (sl)
WO (1) WO2014035289A1 (sl)
ZA (1) ZA201500909B (sl)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2558294C1 (ru) * 2014-09-16 2015-07-27 Общество с ограниченной ответственностью "НекстГен" Кодон-оптимизированная рекомбинантная плазмида, способ стимуляции регенерации периферического нерва, способ лечения поврежденного нерва человека
RU2612497C2 (ru) 2015-05-26 2017-03-09 Общество с ограниченной ответственностью "НекстГен" Оптимизированная нуклеотидная последовательность и фармацевтическая композиция на ее основе с пролонгированной экспрессией трансгена vegf
RU2694826C1 (ru) * 2018-06-05 2019-07-17 Юрий Валентинович Червяков Способ лечения хронической ишемии нижних конечностей атеросклеротического генеза при окклюзии артерий голени
EP3833244A4 (en) * 2018-08-08 2022-08-03 Brightspec, Inc. LOW VOLATILITY SAMPLING METHODS AND APPARATUS
CN110760542B (zh) * 2019-11-18 2022-07-26 天津大学 一种共表达znf580和vegf165双基因的质粒及应用

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998040508A1 (en) * 1997-03-14 1998-09-17 Selective Genetics, Inc. Adenoviral vectors with modified tropism
US6627436B2 (en) * 1997-10-31 2003-09-30 Stratagene Vector for gene expression in prokaryotic and eukaryotic systems
CN100471522C (zh) * 1998-03-13 2009-03-25 惠氏 聚核苷酸组合物及其制备方法与用途
WO2000047235A2 (en) * 1999-02-10 2000-08-17 The Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Methods of stimulating angiogenesis
US7087411B2 (en) * 1999-06-08 2006-08-08 Regeneron Pharmaceuticals, Inc. Fusion protein capable of binding VEGF
US7288521B2 (en) 2000-04-06 2007-10-30 Franco Wayne P Growth factor therapy mobilization of stem cells into the peripheral blood
CN1351055A (zh) 2000-10-26 2002-05-29 上海博德基因开发有限公司 一种新的多肽——人的血管内皮生长因子165受体(vegf-165r)10.67和编码这种多肽的多核苷酸
US7981863B2 (en) * 2001-09-19 2011-07-19 Neuronova Ab Treatment of Parkinson's disease with PDGF
CN100431611C (zh) 2002-07-04 2008-11-12 朱静亚 多肽-脂质体与人血管内皮生长因子基因重组质粒复合物及用途
US7259149B2 (en) * 2002-12-02 2007-08-21 Anges Mg, Inc. Methods for treating or preventing angiogenesis-dependent symptoms
EA011554B1 (ru) * 2004-09-17 2009-04-28 Сентелион Стабильные жидкие композиции плазмидной днк
RU2297848C2 (ru) * 2005-05-11 2007-04-27 Александр Веньяминович Иткес Генно-инженерная конструкция vegf-ибмед (vegf-ibmed)
ES2338400B1 (es) 2008-05-06 2011-09-14 David Benet Ferrus Conjunto de moleculas antiangiogenicas y su uso.
US8367350B2 (en) * 2009-04-29 2013-02-05 Morehouse School Of Medicine Compositions and methods for diagnosis, prognosis and management of malaria

Also Published As

Publication number Publication date
CA2881799A1 (en) 2014-03-06
PL2890777T3 (pl) 2017-07-31
CN105308173B (zh) 2020-03-17
MX2015002658A (es) 2015-09-25
US9616103B2 (en) 2017-04-11
BR112015002522A2 (pt) 2017-11-07
HUE032520T2 (en) 2017-10-30
BR112015002522B1 (pt) 2022-04-05
MX360980B (es) 2018-11-22
EP2890777A4 (en) 2015-12-16
CA2881799C (en) 2019-10-29
EP2890777A1 (en) 2015-07-08
ES2621675T3 (es) 2017-07-04
EP2890777B1 (en) 2017-01-11
ZA201500909B (en) 2016-10-26
WO2014035289A1 (en) 2014-03-06
WO2014035289A9 (en) 2014-05-08
RU2012137126A (ru) 2014-03-10
RU2542385C2 (ru) 2015-02-20
US20150335711A1 (en) 2015-11-26
CN105308173A (zh) 2016-02-03

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