SG47844A1 - A process for the preparation of alkylphosphocholines and the production thereof in pure form - Google Patents
A process for the preparation of alkylphosphocholines and the production thereof in pure formInfo
- Publication number
- SG47844A1 SG47844A1 SG1996004669A SG1996004669A SG47844A1 SG 47844 A1 SG47844 A1 SG 47844A1 SG 1996004669 A SG1996004669 A SG 1996004669A SG 1996004669 A SG1996004669 A SG 1996004669A SG 47844 A1 SG47844 A1 SG 47844A1
- Authority
- SG
- Singapore
- Prior art keywords
- alkylphosphocholines
- ion exchanger
- preparation
- production
- reaction
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 2
- 238000002360 preparation method Methods 0.000 title abstract 2
- 238000004519 manufacturing process Methods 0.000 title 1
- 150000002500 ions Chemical class 0.000 abstract 3
- NBIIXXVUZAFLBC-UHFFFAOYSA-N Phosphoric acid Chemical compound OP(O)(O)=O NBIIXXVUZAFLBC-UHFFFAOYSA-N 0.000 abstract 2
- 238000006243 chemical reaction Methods 0.000 abstract 2
- 239000012442 inert solvent Substances 0.000 abstract 2
- XHXFXVLFKHQFAL-UHFFFAOYSA-N phosphoryl trichloride Chemical compound ClP(Cl)(Cl)=O XHXFXVLFKHQFAL-UHFFFAOYSA-N 0.000 abstract 2
- 239000000126 substance Substances 0.000 abstract 2
- VEXZGXHMUGYJMC-UHFFFAOYSA-M Chloride anion Chemical compound [Cl-] VEXZGXHMUGYJMC-UHFFFAOYSA-M 0.000 abstract 1
- 239000004381 Choline salt Substances 0.000 abstract 1
- 230000002378 acidificating effect Effects 0.000 abstract 1
- 229910000147 aluminium phosphate Inorganic materials 0.000 abstract 1
- 239000007795 chemical reaction product Substances 0.000 abstract 1
- 235000019417 choline salt Nutrition 0.000 abstract 1
- 150000005690 diesters Chemical class 0.000 abstract 1
- 230000007062 hydrolysis Effects 0.000 abstract 1
- 238000006460 hydrolysis reaction Methods 0.000 abstract 1
- 238000002955 isolation Methods 0.000 abstract 1
- 238000005580 one pot reaction Methods 0.000 abstract 1
- 238000000746 purification Methods 0.000 abstract 1
- 150000003248 quinolines Chemical class 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/06—Phosphorus compounds without P—C bonds
- C07F9/08—Esters of oxyacids of phosphorus
- C07F9/09—Esters of phosphoric acids
- C07F9/091—Esters of phosphoric acids with hydroxyalkyl compounds with further substituents on alkyl
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Health & Medical Sciences (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Solid-Sorbent Or Filter-Aiding Compositions (AREA)
- Steroid Compounds (AREA)
- Treatment Of Liquids With Adsorbents In General (AREA)
- Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Cephalosporin Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE4122127 | 1991-07-04 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG47844A1 true SG47844A1 (en) | 1998-04-17 |
Family
ID=6435410
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG1996004669A SG47844A1 (en) | 1991-07-04 | 1992-05-26 | A process for the preparation of alkylphosphocholines and the production thereof in pure form |
Country Status (19)
| Country | Link |
|---|---|
| EP (1) | EP0521297B1 (no) |
| JP (1) | JP3171279B2 (no) |
| CN (1) | CN1034941C (no) |
| AT (1) | ATE158295T1 (no) |
| AU (2) | AU652646B2 (no) |
| CA (1) | CA2073126C (no) |
| DE (2) | DE59208905D1 (no) |
| DK (1) | DK0521297T3 (no) |
| EG (1) | EG20551A (no) |
| ES (1) | ES2108715T3 (no) |
| FI (1) | FI107260B (no) |
| GR (1) | GR3025490T3 (no) |
| HU (1) | HU219243B (no) |
| IE (1) | IE80555B1 (no) |
| IL (1) | IL102379A (no) |
| NO (2) | NO304232B1 (no) |
| PL (1) | PL169571B1 (no) |
| SG (1) | SG47844A1 (no) |
| ZA (1) | ZA924980B (no) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2086026T3 (es) * | 1991-07-04 | 1996-06-16 | Asta Medica Ag | Farmaco con efecto antineoplasico que contiene como sustancia activa (2-(n-metil-piperidino)-etil)-fosfato de octadecilo y procedimiento para su preparacion. |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4444766A (en) * | 1980-10-21 | 1984-04-24 | Boehringer Mannheim Gmbh | Sulfur-containing phospholipid compounds and therapeutic compositions |
| JPS60184092A (ja) * | 1984-03-01 | 1985-09-19 | Kao Corp | リン酸エステルおよびその製法 |
| IE59778B1 (en) * | 1985-12-04 | 1994-04-06 | Max Planck Gesellschaft | Medicament with anti-tumour action containing hexadecylphosphocholine |
| EP0336142A3 (en) * | 1988-04-04 | 1991-04-24 | American Cyanamid Company | Novel antagonists of platelet activating factor |
| IT1229238B (it) * | 1989-05-08 | 1991-07-26 | Istituto Chemioterapico | Procedimento per la preparazione di l-alfa-glicerilfosforilcolina e l alfa glicerilfosforiletanolammina. |
-
1992
- 1992-05-26 ES ES92108826T patent/ES2108715T3/es not_active Expired - Lifetime
- 1992-05-26 SG SG1996004669A patent/SG47844A1/en unknown
- 1992-05-26 AT AT92108826T patent/ATE158295T1/de active
- 1992-05-26 DK DK92108826.6T patent/DK0521297T3/da active
- 1992-05-26 DE DE59208905T patent/DE59208905D1/de not_active Expired - Lifetime
- 1992-05-26 EP EP92108826A patent/EP0521297B1/de not_active Expired - Lifetime
- 1992-06-25 DE DE4220852A patent/DE4220852C2/de not_active Expired - Lifetime
- 1992-07-01 EG EG34492A patent/EG20551A/xx active
- 1992-07-02 PL PL92295129A patent/PL169571B1/pl unknown
- 1992-07-02 NO NO922612A patent/NO304232B1/no not_active IP Right Cessation
- 1992-07-02 IL IL10237992A patent/IL102379A/en not_active IP Right Cessation
- 1992-07-03 CN CN92105432A patent/CN1034941C/zh not_active Expired - Lifetime
- 1992-07-03 ZA ZA924980A patent/ZA924980B/xx unknown
- 1992-07-03 HU HU9202233A patent/HU219243B/hu unknown
- 1992-07-03 IE IE922182A patent/IE80555B1/en not_active IP Right Cessation
- 1992-07-03 FI FI923087A patent/FI107260B/fi not_active IP Right Cessation
- 1992-07-03 AU AU19441/92A patent/AU652646B2/en not_active Expired
- 1992-07-03 CA CA002073126A patent/CA2073126C/en not_active Expired - Lifetime
- 1992-07-03 JP JP17691392A patent/JP3171279B2/ja not_active Expired - Lifetime
-
1994
- 1994-06-29 AU AU66059/94A patent/AU663259B2/en not_active Expired
-
1997
- 1997-11-26 GR GR970403139T patent/GR3025490T3/el unknown
-
1998
- 1998-04-17 NO NO981742A patent/NO304316B1/no not_active IP Right Cessation
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| IL205426A0 (en) | A process for the preparation of alkyl-and aryl-diphosphonic acids | |
| EG20551A (en) | A process for the preparation of alkylphosphacholines and the production thereof in pure form | |
| MA19682A1 (fr) | Procede de production d'acide phosphorique et de produits supplementaires a partir de minerai de phosphate | |
| YU42958B (en) | Process for phosphoric acid purifying | |
| PT87916A (pt) | Processo para a preparacao de fosfono-alquil-fosfinatos de aminometileno | |
| IL116601A0 (en) | 4, 5, 6, 7 tetrahydro-2-saccharinylmethyl phosphates phosphonates and phosphinates and pharmaceutical compositions containing them | |
| AU1024976A (en) | Pyrimidinyl %thiono<-%thiol<phosphoric%phosphonic< acid esters | |
| RO70908A (fr) | Procede de preparation des esteramides de l'acide o-(1-fluore-z-halogenethyle)(thiono)phosphorique(phosphonique) | |
| EP0230355A3 (en) | Process for production of dialkali metal phosphates by ion exchange | |
| JPS54117426A (en) | Organic phosphorus compounds having 22hydroxyalkyl phosphoric acid group | |
| DE50003163D1 (de) | Verfahren zur Herstellung von Alkylphosphonigsäureestern | |
| Van Wazer | The chemistry of phosphates | |
| ZA825510B (en) | Oxo-quinazoline-(thiono)-phosphoric(phosphonic)acid esters and ester-amides,a process for their preparation and their use as pest-combating agents | |
| JPS51131831A (en) | Neutralization process for 2*33dibromopropanol acidic phosphoric acid ester contained in tris*2*33dibromoo11propyl* phosphate | |
| ZA773597B (en) | Substituted pyridazinyl(thiono)(thiol)-phosphoric(phosphonic)acid ester derivatives,process for their preparation and their use as insecticides or acaricides | |
| FR2304616A1 (fr) | Procede de preparation de l'ester de o,o-dimethyle ou o,o-diethyle et o-(2,2-dichlorovinyle) de l'acide thionophosphorique | |
| MA20927A1 (fr) | Procede de production d'acide phosphorique hautement concentre | |
| Shaw et al. | Second Session Chemistry, Biochemistry, and Pharmacology of Edible Phosphates | |
| AR246743A1 (es) | Procedimiento para preparar acido n,n-dimetil-3-amino-1-hidroxi-propiliden-bis-fosfonico y sus sales. | |
| ZA861099B (en) | Process for making wet-process phosphoric acid |