Nothing Special   »   [go: up one dir, main page]

SG44685G - 7-amino-1-cyclopropyl-4-oxo-1,4-dihydronaphthyridine-3-carboxylic acids,process for their preparation and pharmaceutical compositions containing them - Google Patents

7-amino-1-cyclopropyl-4-oxo-1,4-dihydronaphthyridine-3-carboxylic acids,process for their preparation and pharmaceutical compositions containing them

Info

Publication number
SG44685G
SG44685G SG44685A SG44685A SG44685G SG 44685 G SG44685 G SG 44685G SG 44685 A SG44685 A SG 44685A SG 44685 A SG44685 A SG 44685A SG 44685 G SG44685 G SG 44685G
Authority
SG
Singapore
Prior art keywords
dihydronaphthyridine
cyclopropyl
oxo
amino
preparation
Prior art date
Application number
SG44685A
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=6111041&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SG44685(G) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of SG44685G publication Critical patent/SG44685G/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D215/54—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
    • C07D215/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3 with oxygen atoms in position 4

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Quinoline Compounds (AREA)
  • Fodder In General (AREA)
  • Medicinal Preparation (AREA)
  • Food Preservation Except Freezing, Refrigeration, And Drying (AREA)
SG44685A 1980-09-03 1985-06-11 7-amino-1-cyclopropyl-4-oxo-1,4-dihydronaphthyridine-3-carboxylic acids,process for their preparation and pharmaceutical compositions containing them SG44685G (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19803033157 DE3033157A1 (en) 1980-09-03 1980-09-03 7-AMINO-1-CYCLOPROPYL-4-OXO-1,4-DIHYDRO-NAPHTHYRIDINE-3-CARBONIC ACIDS, METHOD FOR THE PRODUCTION THEREOF AND THE ANTIBACTERIAL AGENTS CONTAINING THEM

Publications (1)

Publication Number Publication Date
SG44685G true SG44685G (en) 1986-01-17

Family

ID=6111041

Family Applications (1)

Application Number Title Priority Date Filing Date
SG44685A SG44685G (en) 1980-09-03 1985-06-11 7-amino-1-cyclopropyl-4-oxo-1,4-dihydronaphthyridine-3-carboxylic acids,process for their preparation and pharmaceutical compositions containing them

Country Status (17)

Country Link
EP (1) EP0049355B1 (en)
JP (3) JPS5777683A (en)
KR (1) KR870000441B1 (en)
AR (1) AR227063A1 (en)
AT (1) ATE9803T1 (en)
AU (1) AU540242B2 (en)
CY (1) CY1301A (en)
DE (2) DE3033157A1 (en)
DK (1) DK161460C (en)
ES (1) ES8206523A1 (en)
HK (1) HK61485A (en)
IE (1) IE51541B1 (en)
KE (1) KE3545A (en)
MY (1) MY8700363A (en)
NL (2) NL930033I1 (en)
SG (1) SG44685G (en)
ZA (1) ZA816080B (en)

Families Citing this family (64)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3142854A1 (en) * 1981-10-29 1983-05-11 Bayer Ag, 5090 Leverkusen 1-CYCLOPROPYL-6-FLUOR-1,4-DIHYDRO-4-OXO-7-PIPERAZINO-CHINOLINE-3-CARBONIC ACIDS, METHOD FOR THE PRODUCTION THEREOF AND THEIR CONTAINING ANTIBACTERIAL AGENTS
JPS5925391A (en) * 1982-07-30 1984-02-09 Dainippon Pharmaceut Co Ltd Pyridylnaphthyridine derivative and salt thereof
US5281612A (en) * 1982-09-09 1994-01-25 Warner-Lambert Company Naphthyridine antibacterial agents
US4665079A (en) * 1984-02-17 1987-05-12 Warner-Lambert Company Antibacterial agents
DE3248505A1 (en) * 1982-12-29 1984-07-05 Bayer Ag, 5090 Leverkusen 1-CYCLOPROPYL-6-FLUOR-1,4-DIHYDRO-4-OXO-7 (4- (OXOALKYL) -1-PIPERAZINYL / -3-QUINOLINE CARBONIC ACIDS AND THEIR DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF, AND THEIR CONTAINERS
DE3248506A1 (en) * 1982-12-29 1984-07-05 Bayer Ag, 5090 Leverkusen 1-CYCLOPROPYL-6-FLUOR-1,4-DIHYDRO-4-OXO-7 (ALKYL-1-PIPERAZINYL) -3-CHINOLINE CARBONIC ACIDS, METHOD FOR THE PRODUCTION THEREOF AND THEIR CONTAINING ANTIBACTERIAL AGENTS
DE3248507A1 (en) * 1982-12-29 1984-07-05 Bayer Ag, 5090 Leverkusen MICROBICIDE AGENTS BASED ON CHINOLONIC CARBONIC ACID
DE3306771A1 (en) * 1983-02-25 1984-08-30 Bayer Ag, 5090 Leverkusen CHINOLONIC CARBONIC ACIDS, METHOD FOR THE PRODUCTION THEREOF AND THE ANTIBACTERIAL AGENTS CONTAINING THEM
DE3306772A1 (en) * 1983-02-25 1984-08-30 Bayer Ag, 5090 Leverkusen CHINOLONIC ACIDS, METHOD FOR THE PRODUCTION THEREOF AND THE ANTIBACTERIAL AGENTS CONTAINING THEM
DE3308909A1 (en) * 1983-03-12 1984-09-13 Bayer Ag, 5090 Leverkusen BACTERICIDALS BASED ON CHINOLONIC CARBONIC ACID
DE3308908A1 (en) * 1983-03-12 1984-09-13 Bayer Ag, 5090 Leverkusen BACTERICIDAL AGENTS
DE3318145A1 (en) * 1983-05-18 1984-11-22 Bayer Ag, 5090 Leverkusen 7-AMINO-1-CYCLOPROPYL-6,8-DIFLUOR-1,4-DIHYDRO-4-OXO-3-CHINOLINE CARBONIC ACIDS, METHOD FOR THE PRODUCTION THEREOF AND THEIR CONTAINING ANTIBACTERIAL AGENTS
JPS6056959A (en) * 1983-07-18 1985-04-02 アボツト　ラボラトリ−ズ Quinoline antifungal compound
DE3326190A1 (en) * 1983-07-20 1985-01-31 Bayer Ag, 5090 Leverkusen 5-CYCLOPROPYL-5,8-DIHYDRO-8-OXO-1,3-DIOXOLO- (4,5-G) QUINOLINE-7-CARBONIC ACID, METHOD FOR THE PRODUCTION THEREOF AND THEIR ANTIBACTERIAL AGENTS CONTAINING THEM
CS274601B2 (en) * 1983-07-27 1991-09-15 Dainippon Pharmaceutical Co Method of 1,8-naphthyridine derivative production
JPS6028978A (en) * 1983-07-27 1985-02-14 Dainippon Pharmaceut Co Ltd 1,8-naphthyridine derivative
JPS60260577A (en) * 1984-06-06 1985-12-23 Dainippon Pharmaceut Co Ltd 1,8-naphthyridine derivative
JPS6032790A (en) * 1983-08-01 1985-02-19 Dainippon Pharmaceut Co Ltd 1,8-naphthyridines
AU553415B2 (en) * 1983-09-19 1986-07-17 Abbott Japan Co., Ltd. 6-fluoro-1-4-dihydro-4-oxo-7-substituted piperazinyl- quinoline-3-carboxylic acids
JPS6089480A (en) * 1983-10-21 1985-05-20 Dainippon Pharmaceut Co Ltd Pyridonecarboxylic acid derivative
US4551456A (en) * 1983-11-14 1985-11-05 Merck & Co., Inc. Ophthalmic use of norfloxacin and related antibiotics
JPS60126284A (en) * 1983-12-09 1985-07-05 Dainippon Pharmaceut Co Ltd Pyridonecarboxylic acid derivative and salt thereof
CA1285279C (en) * 1984-02-17 1991-06-25 Joseph P. Sanchez 7-amine derivatives of 1-cyclopropyl-6,8-difluoro-1,4- dihydro-4-oxo-3-quinolinecarboxylic acids and 1-cyclopropyl-1,4-dihydro-6-fluoro-4-oxo-1,8-naphthyridine- 3-carboxylic acidsas antibacterial agents
DE3574380D1 (en) * 1984-02-17 1989-12-28 Daiichi Seiyaku Co 1,8-naphthyridine derivatives
JPS60228479A (en) * 1984-04-26 1985-11-13 Toyama Chem Co Ltd 1,4-dihydro-4-oxonaphthyridine derivative and salt thereof
US4732311A (en) * 1984-05-31 1988-03-22 Nippondenso Co., Ltd. Process of producing lightweight and corrosion-resistant heat exchanger
DE3420743A1 (en) * 1984-06-04 1985-12-05 Bayer Ag, 5090 Leverkusen 7-AMINO-1-CYCLOPROPYL-6,8-DIHALOGEN-1,4-DIHYDRO-4-OXO-3-CHINOLINE CARBONIC ACIDS, METHOD FOR THE PRODUCTION THEREOF AND THEIR CONTAINING ANTIBACTERIAL AGENTS
US5468861A (en) * 1984-06-04 1995-11-21 Bayer Aktiengesellschaft 8-chloro-1-cyclopropyl-6,7-difluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid and alkyl esters thereof
DE3420770A1 (en) * 1984-06-04 1985-12-05 Bayer Ag, 5090 Leverkusen 1-CYCLOPROPYL-6-FLUOR-1,4-DIHYDRO-4-OXO-7- (3-OXO-1-PIPERAZINYL) -3-CHINOLONIC CARBONIC ACIDS, METHOD FOR THE PRODUCTION THEREOF AND THEIR CONTAINING ANTIBACTERIAL AGENTS
DE3420798A1 (en) * 1984-06-04 1985-12-05 Bayer Ag, 5090 Leverkusen 7- (3-ARYL-L-PIPERAZINYL) - AND 7- (3-CYCLOHEXYL-L-PIPERAZINYL) -3-CHINOLONIC CARBONIC ACIDS
IE58742B1 (en) * 1984-07-20 1993-11-05 Warner Lambert Co Substituted-9-fluoro-3-methyl-7-oxo-2,3-dihydro-7h-pyrido[1,2,3-de] [1,4]benzoxauine-6-carboxylic acids; sibstituted-5-amino-6-6fluoro-4-oxo.1,4-dihydroquinoline-3 carboxylic acids; substituted-5-amino-6-fluoro-1,4-dihydro-4-oxo-1.8-naphthyridine-3-carboxylic acids; derivatives thereof; pharmaceutical compositions comprising the compounds; and processes for producing the compounds
JPS61118370A (en) * 1985-10-30 1986-06-05 Kyorin Pharmaceut Co Ltd Quinolonecarboxylic acid and its preparation
IN162769B (en) * 1984-11-13 1988-07-09 Kyorin Seiyaku Kk
DE3517709A1 (en) * 1985-01-05 1986-07-10 Bayer Ag BASIC PREPARATIONS OF CHINOLON CARBON ACIDS
JPS61180771A (en) * 1985-01-05 1986-08-13 バイエル・アクチエンゲゼルシヤフト Basic prescription of quinolone carboxylic acid
DE3508816A1 (en) * 1985-01-10 1986-07-10 Bayer Ag, 5090 Leverkusen 6,7-DISUBSTITUTED 1-CYCLOPROPYL-1,4-DIHYDRO-4-OXO-1,8-NAPHTYRIDINE-3-CARBONIC ACIDS
DE3504643A1 (en) * 1985-02-12 1986-08-14 Bayer Ag, 5090 Leverkusen 1-CYCLOPROPYL-1,4-DIHYDRO-4-OXO-7- (4- (2-OXO-1,3-DIOXOL-4-YL-METHYL) -1-PIPERAZINYL) -3-QUINOLINE CARBONIC ACIDS, METHOD FOR YOURSELF PRODUCTION AND THIS ANTIBACTERIAL AGENT
DE3509546A1 (en) * 1985-03-16 1986-09-25 Bayer Ag, 5090 Leverkusen 7-AMINO-1- (SUBST.CYCLOPROPYL) -1,4-DIHYDRO-4-OXO-3-CHINOLINE CARBONIC ACIDS, METHOD FOR THE PRODUCTION THEREOF AND THE ANTIBACTERIAL AGENTS CONTAINING THEM
IT1200470B (en) * 1985-05-10 1989-01-18 Schering Spa ANTIBACTERIAL ACTIVITY COMPOUNDS, THEIR PREPARATION AND RELATED PHARMACEUTICAL COMPOSITIONS
GB8512143D0 (en) * 1985-05-14 1985-06-19 Beecham Group Plc Method of treatment
DE3519286A1 (en) * 1985-05-30 1986-12-04 Bayer Ag, 5090 Leverkusen 7-AZOLYL-1-CYCLOPROPYL-1,4-DIHYDRO-4-OXO-3-CHINOLINE CARBONIC ACIDS AND -1,8-NAPHTHYRIDINE-3-CARBONIC ACIDS, METHOD FOR THE PRODUCTION THEREOF AND THEIR ANTIBACTERS CONTAINING THEM
DE3608745A1 (en) * 1985-07-24 1987-01-29 Bayer Ag BACTERICIDAL PREPARATIONS FOR APPLICATION IN THE VETERINE MEDICINE AREA
AU594983B2 (en) * 1985-10-29 1990-03-22 Dainippon Pharmaceutical Co. Ltd. Novel quinoline derivatives and processes for preparation thereof
EP0224121A3 (en) * 1985-11-19 1987-11-11 ROTTAPHARM S.p.A. 7-[4-amino-piperazinyl]- or 7-[4-chloro-piperazinyl]quinolinone derivatives, a process for the preparation thereof and pharmaceutical compositions containing them
DE3542002A1 (en) * 1985-11-28 1987-06-04 Bayer Ag 1-CYCLOPROPYL-6-FLUOR-1,4-DIHYDRO-4-OXO-7- (1-PIPERAZINYL) -3-QUINOLINE CARBONIC ACIDS, METHOD FOR THE PRODUCTION THEREOF AND THEIR ANTIBACTERIAL AGENTS CONTAINING THEM
US4668680A (en) * 1985-12-12 1987-05-26 Warner-Lambert Company 5-amino-6,8-difluoroquinolones as antibacterial agents
US5286754A (en) * 1986-01-21 1994-02-15 Bayer Aktiengesellschaft Pharmaceutical formulations of ciprofloxacin
DE3601566A1 (en) * 1986-01-21 1987-07-23 Bayer Ag PHARMACEUTICAL PREPARATIONS OF CIPROFLOXACIN
US4692454A (en) * 1986-02-03 1987-09-08 Warner-Lambert Company Opthalmic use of quinolone antibiotics
DE3705621C2 (en) * 1986-02-25 1997-01-09 Otsuka Pharma Co Ltd Heterocyclic substituted quinolonecarboxylic acid derivatives
HU198709B (en) * 1987-04-08 1989-11-28 Chinoin Gyogyszer Es Vegyeszet Process for producing quinoline-carboxylic acid derivatives
DE3713672A1 (en) * 1987-04-24 1988-11-17 Bayer Ag METHOD FOR PRODUCING PARENTERALLY AVAILABLE CHINOLONIC CARBONIC ACIDS
DE3719764A1 (en) * 1987-06-13 1988-12-22 Bayer Ag ION EXCHANGE RESINS LOADED WITH CHINOLON CARBONIC ACID DERIVATIVES, THEIR PRODUCTION AND USE
DE3902079A1 (en) * 1988-04-15 1989-10-26 Bayer Ag IN THE. INJECTION FORMS OF GYRASE INHIBITORS
PT726270E (en) 1995-02-09 2001-08-30 Bayer Ag DERIVATIVES OF 1,6-NAFTIRIDONOCARBOXYLIC ACID
DE19519822A1 (en) * 1995-05-31 1996-12-05 Bayer Ag New antibacterial agents
IT1280428B1 (en) * 1995-07-14 1998-01-20 R R A S R L PHARMACEUTICAL COMPOSITION FOR TOPICAL USE
CN1343128B (en) 1999-03-17 2010-04-21 第一制药株式会社 Medicinal compositions
SE9904108D0 (en) 1999-11-15 1999-11-15 New Pharma Research Ab New compounds
JP4290381B2 (en) * 2002-04-11 2009-07-01 学校法人 聖マリアンナ医科大学 Emulsion containing pyridonecarboxylic acid compound
DK1594500T3 (en) 2003-02-10 2011-01-24 Bayer Schering Pharma Ag Treatment of bacterial diseases of the respiratory organs by local application of fluoroquinolones
DE102007004732A1 (en) 2007-01-31 2008-08-07 Bayer Healthcare Ag Enrofloxacin hexahydrate
WO2011031745A1 (en) 2009-09-09 2011-03-17 Achaogen, Inc. Antibacterial fluoroquinolone analogs
EP2957561A1 (en) 2014-06-18 2015-12-23 Université Paris 6 Pierre et Marie Curie UPMC Novel fluoroquinolones and use thereof to treat bacterial infections

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS4843508A (en) * 1971-10-05 1973-06-23
JPS5635188B2 (en) * 1974-02-12 1981-08-15
JPS5732059B2 (en) * 1974-02-09 1982-07-08
JPS587626B2 (en) * 1974-02-13 1983-02-10 大日本製薬株式会社 Naphthyridine and quinoline
JPS5437151A (en) * 1977-08-29 1979-03-19 Mizusawa Industrial Chem Method of improving basic lead sulfate
SE444566B (en) * 1977-09-20 1986-04-21 Bellon Labor Sa Roger 7-DIALKYLAMINE-6-HALOGEN-4-OXO-1,4-DIHYDROQINOLINE-3-CARBOXYLIC ACID, PROCEDURES FOR PREPARING THEREOF AND PHARMACEUTICAL PREPARATION OF THEREOF
JPS5466686A (en) * 1977-09-20 1979-05-29 Dainippon Pharmaceut Co Ltd Quinoline-3-carboxylic acid derivative, its preparation, and pharmaceutical composition containig the same
DE2808070A1 (en) * 1978-02-24 1979-08-30 Bayer Ag PROCESS FOR THE PRODUCTION OF 4-PYRIDONE-3-CARBONIC ACIDS AND / OR DERIVATIVES
JPS5845426B2 (en) * 1978-09-29 1983-10-08 杏林製薬株式会社 Substituted quinoline carboxylic acid derivatives
DE2903850A1 (en) * 1979-02-01 1980-08-07 Bayer Ag 2-AMINO-8-CYCLOPROPYL-5-OXO-5,8- DIHYDRO-PYRIDO CORNER CLAMP ON 2,3-D CORNER CLAMP FOR -PYRIMIDINE-6-CARNONIC ACIDS, METHOD FOR THE PRODUCTION AND USE THEREOF

Also Published As

Publication number Publication date
DE3033157A1 (en) 1982-04-01
EP0049355A1 (en) 1982-04-14
AU7468081A (en) 1982-03-11
IE51541B1 (en) 1987-01-07
HK61485A (en) 1985-08-23
ATE9803T1 (en) 1984-10-15
MY8700363A (en) 1987-12-31
EP0049355B1 (en) 1984-10-10
ES505138A0 (en) 1982-08-16
IE812032L (en) 1982-03-03
DK387781A (en) 1982-03-04
JPH0314811B2 (en) 1991-02-27
DK161460C (en) 1991-12-16
JPS62161728A (en) 1987-07-17
CY1301A (en) 1985-12-06
NL930032I1 (en) 1993-08-02
AU540242B2 (en) 1984-11-08
NL930032I2 (en) 1997-03-03
KR830007642A (en) 1983-11-04
ES8206523A1 (en) 1982-08-16
NL930033I1 (en) 1993-08-02
AR227063A1 (en) 1982-09-15
KR870000441B1 (en) 1987-03-10
ZA816080B (en) 1982-08-25
JPS5777683A (en) 1982-05-15
JPS6356224B2 (en) 1988-11-07
JPS62161763A (en) 1987-07-17
KE3545A (en) 1985-07-19
DK161460B (en) 1991-07-08
DE3166619D1 (en) 1984-11-15
JPH0316344B2 (en) 1991-03-05

Similar Documents

Publication Publication Date Title
DE3166619D1 (en) 7-amino-1-cyclopropyl-4-oxo-1,4-dihydro-naphthyridine-3-carboxylic acids, process for their preparation and pharmaceutical compositions containing them
DE3263633D1 (en) Imidazodiazepines, process for their preparation and pharmaceutical compositions containing them
DE3064173D1 (en) Novel 20-0-acylmaytansinoids, process for their preparation and pharmaceutical compositions containing them
IL62082A0 (en) -lactam derivatives,process for the preparation thereof and pharmaceutical compositions containing them
IL65346A0 (en) N-substituted amido-amino acids,process for their preparation and pharmaceutical compositions comprising them
PH18036A (en) Polypeptides,their pharmaceutical compositions and process for their preparation
DE3461090D1 (en) 11-beta-aryl-estradienes, process for their preparation and pharmaceutical compositions containing them
DE3165428D1 (en) Substituted azobicyclooctanecarboxylic acids, process for their preparation und pharmaceutical compositions containing them
DE3160805D1 (en) Antiallergic imidodisulfamides, pharmaceutical compositions containing them and process for their preparation
IL56612A (en) 1-aryloxy-3-nitratoalkylamino-2-propanols,process for their preparation,and pharmaceutical compositions comprising them
IL65247A0 (en) Amido-amino acids,process for their preparation and pharmaceutical compositions containing them
EP0145121A3 (en) Pyrazoloquinolines, process for their preparation, and pharmaceutical compositions containing them
DE3161238D1 (en) 20-deoxyrosaramicin derivatives, process for their preparation and pharmaceutical compositions containing them
DE3060861D1 (en) Monophosphonate compounds, process for their preparation and pharmaceutical compositions containing them
DE3168902D1 (en) Epoxy-cycloalkylalkanecarboxylic acids, process for their preparation, their use and medicaments containing them
IL68680A (en) 2,3,4-trinor-1,5-inter-m-phenylene-prostacyclin-i2-analogues,process for their preparation and pharmaceutical compositions containing them
IL69735A (en) 1-phenyl-1-aminoalkyl-cyclobutane derivatives,process for their preparation and pharmaceutical compositions containing them
IL60907A0 (en) Substituted quinoline-alkanecarboxylic acids,process for their preparation and pharmaceutical compositions containing them
IL64123A (en) Biphenylyloxypropoxypyrimidine derivatives,process for their preparation and pharmaceutical compositions containing them
GB2138817B (en) 4-pheny-tetrahydro-furano-pyridines, process for their preparation, and pharmaceutical compositions containing them
DE3163490D1 (en) 1,2,4-triazinylthiomethyl-3-cephem sulfoxides, process for their preparation and pharmaceutical compositions containing them
ZA818609B (en) Pyrimidones,process for their preparation and pharmaceutical compositions containing them
IL61902A (en) Kijanimicin,process for its preparation and pharmaceutical compositions containing it
IL62890A0 (en) Alkoxy-acyl carnitines,process for their preparation and pharmaceutical compositions containing same
DE3167471D1 (en) Benzoquinolizines, processes for their preparation and pharmaceutical compositions