SG132542A1 - Modifying nicotine and nitrosamine levels in tobacco - Google Patents
Modifying nicotine and nitrosamine levels in tobaccoInfo
- Publication number
- SG132542A1 SG132542A1 SG200507529-6A SG2005075296A SG132542A1 SG 132542 A1 SG132542 A1 SG 132542A1 SG 2005075296 A SG2005075296 A SG 2005075296A SG 132542 A1 SG132542 A1 SG 132542A1
- Authority
- SG
- Singapore
- Prior art keywords
- tobacco
- nitrosamine levels
- nicotine
- modifying
- modifying nicotine
- Prior art date
Links
Classifications
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- A—HUMAN NECESSITIES
- A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
- A24B—MANUFACTURE OR PREPARATION OF TOBACCO FOR SMOKING OR CHEWING; TOBACCO; SNUFF
- A24B15/00—Chemical features or treatment of tobacco; Tobacco substitutes, e.g. in liquid form
- A24B15/18—Treatment of tobacco products or tobacco substitutes
- A24B15/24—Treatment of tobacco products or tobacco substitutes by extraction; Tobacco extracts
- A24B15/241—Extraction of specific substances
- A24B15/243—Nicotine
-
- A—HUMAN NECESSITIES
- A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
- A24B—MANUFACTURE OR PREPARATION OF TOBACCO FOR SMOKING OR CHEWING; TOBACCO; SNUFF
- A24B15/00—Chemical features or treatment of tobacco; Tobacco substitutes, e.g. in liquid form
- A24B15/10—Chemical features of tobacco products or tobacco substitutes
-
- A—HUMAN NECESSITIES
- A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
- A24B—MANUFACTURE OR PREPARATION OF TOBACCO FOR SMOKING OR CHEWING; TOBACCO; SNUFF
- A24B15/00—Chemical features or treatment of tobacco; Tobacco substitutes, e.g. in liquid form
- A24B15/18—Treatment of tobacco products or tobacco substitutes
-
- A—HUMAN NECESSITIES
- A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
- A24B—MANUFACTURE OR PREPARATION OF TOBACCO FOR SMOKING OR CHEWING; TOBACCO; SNUFF
- A24B15/00—Chemical features or treatment of tobacco; Tobacco substitutes, e.g. in liquid form
- A24B15/18—Treatment of tobacco products or tobacco substitutes
- A24B15/20—Biochemical treatment
-
- A—HUMAN NECESSITIES
- A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
- A24B—MANUFACTURE OR PREPARATION OF TOBACCO FOR SMOKING OR CHEWING; TOBACCO; SNUFF
- A24B15/00—Chemical features or treatment of tobacco; Tobacco substitutes, e.g. in liquid form
- A24B15/18—Treatment of tobacco products or tobacco substitutes
- A24B15/24—Treatment of tobacco products or tobacco substitutes by extraction; Tobacco extracts
- A24B15/241—Extraction of specific substances
- A24B15/245—Nitrosamines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/34—Tobacco-abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/415—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from plants
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
- C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
- C12N15/8243—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/1048—Glycosyltransferases (2.4)
- C12N9/1077—Pentosyltransferases (2.4.2)
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- General Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Biophysics (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- Botany (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Nutrition Science (AREA)
- Public Health (AREA)
- Physics & Mathematics (AREA)
- Veterinary Medicine (AREA)
- Plant Pathology (AREA)
- Addiction (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Gastroenterology & Hepatology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Psychiatry (AREA)
- Manufacture Of Tobacco Products (AREA)
- Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US29715401P | 2001-06-08 | 2001-06-08 |
Publications (1)
Publication Number | Publication Date |
---|---|
SG132542A1 true SG132542A1 (en) | 2007-06-28 |
Family
ID=23145081
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG200507529-6A SG132542A1 (en) | 2001-06-08 | 2002-06-06 | Modifying nicotine and nitrosamine levels in tobacco |
Country Status (18)
Country | Link |
---|---|
US (5) | US6907887B2 (hu) |
EP (1) | EP1406518A4 (hu) |
JP (2) | JP2004530430A (hu) |
KR (1) | KR20040019301A (hu) |
CN (1) | CN1638655A (hu) |
AR (1) | AR040059A1 (hu) |
CA (1) | CA2449920A1 (hu) |
EA (1) | EA200400013A1 (hu) |
HU (1) | HUP0400161A2 (hu) |
IL (2) | IL159213A0 (hu) |
MX (1) | MXPA03011385A (hu) |
NZ (1) | NZ530238A (hu) |
PL (1) | PL367438A1 (hu) |
SG (1) | SG132542A1 (hu) |
TW (1) | TWI258340B (hu) |
UY (1) | UY27326A1 (hu) |
WO (1) | WO2002100199A2 (hu) |
ZA (1) | ZA200400084B (hu) |
Families Citing this family (77)
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US6586661B1 (en) * | 1997-06-12 | 2003-07-01 | North Carolina State University | Regulation of quinolate phosphoribosyl transferase expression by transformation with a tobacco quinolate phosphoribosyl transferase nucleic acid |
DE19926216A1 (de) * | 1999-06-09 | 2001-02-22 | Metallgesellschaft Ag | Verfahren zur Herstellung von Bariumsulfat, Bariumsulfat und Verwendung des Bariumsulfats |
DE60121603T2 (de) * | 2000-08-30 | 2007-06-21 | North Carolina State University | Transgene pflanzen, die molekulare decoys enthalten, die den proteininhalt ändern |
ATE360701T1 (de) * | 2000-11-07 | 2007-05-15 | Univ North Carolina State | Putrescin-n-methyltransferasepromotor |
MXPA03011101A (es) * | 2001-06-06 | 2005-02-17 | 22Nd Century Ltd Llc | Utilizacion de biomasa de tabaco. |
US20060157072A1 (en) * | 2001-06-08 | 2006-07-20 | Anthony Albino | Method of reducing the harmful effects of orally or transdermally delivered nicotine |
KR20040019301A (ko) * | 2001-06-08 | 2004-03-05 | 벡터 토바코 리미티드 | 담배에서 니코틴 및 니트로사민 수준의 조절 |
US6730832B1 (en) | 2001-09-10 | 2004-05-04 | Luis Mayan Dominguez | High threonine producing lines of Nicotiana tobacum and methods for producing |
EP1441603A2 (en) * | 2001-11-09 | 2004-08-04 | Vector Tobacco Inc. | Method and composition for mentholation of charcoal filtered cigarettes |
US20040111759A1 (en) * | 2001-11-13 | 2004-06-10 | U.S. Smokeless Tobacco Company | Identification and use of cytochrome P450 nucleic acid sequences from tobacco |
US7812227B2 (en) | 2001-11-13 | 2010-10-12 | U.S. Smokeless Tobacco Company | Cloning of cytochrome p450 genes from nicotiana |
US7700834B2 (en) * | 2001-11-13 | 2010-04-20 | U.S. Smokless Tobacco Company | Nicotiana nucleic acid molecules and uses thereof |
US7700851B2 (en) * | 2001-11-13 | 2010-04-20 | U.S. Smokeless Tobacco Company | Tobacco nicotine demethylase genomic clone and uses thereof |
US10266836B2 (en) | 2001-11-13 | 2019-04-23 | U.S. Smokeless Tobacco Company Llc | Tobacco nicotine demethylase genomic clone and uses thereof |
US7855318B2 (en) * | 2001-11-13 | 2010-12-21 | U.S. Smokeless Tobacco Company | Cloning of cytochrome P450 genes from Nicotiana |
US20040117869A1 (en) * | 2002-01-11 | 2004-06-17 | U.S. Smokeless Tobacco Company | Cloning of cytochrome P450 genes from Nicotiana |
US8592663B2 (en) * | 2001-11-13 | 2013-11-26 | U.S. Smokeless Tobacco Company Llc | Tobacco nicotine demethylase genomic clone and uses thereof |
US20040162420A1 (en) * | 2002-10-16 | 2004-08-19 | U.S. Smokeless Tobacco Company | Cloning of cytochrome p450 genes from nicotiana |
AU2002357903A1 (en) * | 2001-12-19 | 2003-07-09 | Vector Tobacco Inc. | Method and composition for mentholation of cigarettes |
AU2002361809A1 (en) * | 2001-12-19 | 2003-07-09 | Vector Tobacco Inc. | Method and compositions for imparting cooling effect to tobacco products |
EA200401332A1 (ru) * | 2002-04-09 | 2005-02-24 | Вектор Тобакко Лтд. | Табак с пониженным содержанием никотина и нитрозаминов |
KR20060032141A (ko) * | 2003-06-04 | 2006-04-14 | 벡터 토바코 리미티드 | 경구적 또는 경피적으로 전달되는 니코틴의 유해효과를감소시키는 방법 |
US7293564B2 (en) * | 2003-06-11 | 2007-11-13 | R. J. Reynolds Tobacco Company | Method for chemically modifying tobacco during curing |
EP1675454A4 (en) * | 2003-08-19 | 2007-03-21 | 22Nd Century Ltd Llc | TOBACCO PRODUCTS WITH REDUCED EXPOSURE |
CN1926235B (zh) | 2003-10-16 | 2012-07-18 | 美国无烟烟草有限责任公司 | 从烟草克隆细胞色素p450基因 |
US8637731B2 (en) * | 2003-10-16 | 2014-01-28 | U.S. Smokeless Tobacco Company | Nicotiana nucleic acid molecules and uses thereof |
US8586837B2 (en) | 2004-04-29 | 2013-11-19 | U.S. Smokeless Tobacco Company Llc | Nicotiana nucleic acid molecules and uses thereof |
US20070199097A1 (en) * | 2004-09-03 | 2007-08-23 | U.S. Smokeless Tobacco Company | Tobacco plants having a mutation in a nicotine demethylase gene |
EP2338905B1 (en) | 2005-02-23 | 2017-11-29 | North Carolina State University | Alteration of tobacco alkaloid content through modification of specific cytochrome p450 genes |
AU2015202209B2 (en) * | 2005-02-28 | 2017-07-06 | 22Nd Century Limited, Llc | Reducing levels of nicotinic alkaloids in plants |
AP2990A (en) * | 2005-02-28 | 2014-09-30 | 22Nd Century Ltd Llc | Reducing levels of nicotinic alkaloids in plants |
AU2012203977B2 (en) * | 2005-02-28 | 2015-01-29 | 22Nd Century Limited, Llc | Reducing levels of nicotinic alkaloids in plants |
US7992575B2 (en) * | 2005-02-28 | 2011-08-09 | U.S. Smokeless Tobacco Company | Use of chlorate, sulfur or ozone to reduce tobacco specific nitrosamines |
AU2006247739A1 (en) * | 2005-05-11 | 2006-11-23 | Vector Tobacco Inc. | Reduced risk tobacco products and methods of making same |
US20090055964A1 (en) * | 2006-07-11 | 2009-02-26 | Gelesko John G | Mpo1 gene and protein and methods of use |
US9551003B2 (en) | 2006-09-13 | 2017-01-24 | 22Nd Century Limited, Llc | Increasing levels of nicotinic alkaloids in plants |
US11332753B2 (en) | 2006-12-15 | 2022-05-17 | U.S. Smokeless Tobacco Company Llc | Tobacco plants having reduced nicotine demethylase activity |
US8319011B2 (en) | 2006-12-15 | 2012-11-27 | U.S. Smokeless Tobacco Company Llc | Tobacco plants having reduced nicotine demethylase activity |
US8822757B2 (en) * | 2007-05-25 | 2014-09-02 | National Research Council Of Canada | Nucleic acid sequences encoding transcription factors regulating nicotine alkaloid biosynthesis and their use in modifying plant metabolism |
US9271524B1 (en) * | 2007-09-07 | 2016-03-01 | U.S. Smokeless Tobacco Company | Tobacco having reduced tobacco specific nitrosamine content |
US20100206317A1 (en) * | 2007-09-28 | 2010-08-19 | Vector Tobacco, Inc. | Reduced risk tobacco products and use thereof |
US7665471B2 (en) | 2007-11-06 | 2010-02-23 | Alliance One International, Inc. | Tobacco cultivar AOB 171 and products therefrom |
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US8124851B2 (en) | 2007-11-12 | 2012-02-28 | North Carolina State University | Alteration of tobacco alkaloid content through modification of specific cytochrome P450 genes |
CN101224042B (zh) * | 2007-12-21 | 2011-03-30 | 湖南中烟工业有限责任公司 | 一种选择性降低卷烟烟气中tsna含量的分子印迹材料及其应用 |
IT1390613B1 (it) * | 2008-07-25 | 2011-09-09 | Uni Degli Studi Di Verona | Metodo di espressione in pianta di gad65 e vettori di espressione relativi. |
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US9862923B2 (en) | 2010-03-26 | 2018-01-09 | Philip Morris Usa Inc. | Cultured tobacco cells as a matrix for consumable products |
RU2013143791A (ru) | 2011-02-28 | 2015-04-10 | Алтрия Клаинт Сервисиз Инк. | Инбредные растения табака albex1f и albex1ms |
KR20140004760A (ko) | 2011-02-28 | 2014-01-13 | 노쓰 캐롤라이나 스테이트 유니버시티 | 담배 근교배 식물 ncbex1f, ncbex1ms 및 nc ex90 |
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US9137958B2 (en) | 2012-02-08 | 2015-09-22 | Reynolds Technologies, Inc. | Tobacco having altered amounts of environmental contaminants |
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WO2014137802A1 (en) | 2013-03-05 | 2014-09-12 | North Carolina State University | Tobacco inbred and hybrid plants and uses thereof |
US10375910B2 (en) | 2013-03-15 | 2019-08-13 | Altria Client Services Llc | Development of tobacco varieties with no or significantly reduced anatabine content |
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EP3113603A1 (en) | 2014-03-03 | 2017-01-11 | North Carolina State University | Tobacco inbred and hybrid plants and tobacco products made thereof |
WO2015134423A1 (en) * | 2014-03-03 | 2015-09-11 | North Carolina State University | Tobacco inbred and hybrid plants and tobacco products made thereof |
US9596824B2 (en) | 2014-03-03 | 2017-03-21 | North Carolina State University | Tobacco inbred and hybrid plants and tobacco products made thereof |
US10111458B1 (en) | 2014-05-16 | 2018-10-30 | R.J. Reynolds Tobacco Company | Process for inhibiting formation of nitrosamines |
CN106998787A (zh) * | 2014-09-26 | 2017-08-01 | 菲利普莫里斯生产公司 | 通过改变硝酸同化路径减少烟草特异性亚硝胺 |
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CN105954403B (zh) * | 2016-04-27 | 2018-10-09 | 中国烟草总公司郑州烟草研究院 | 一种卷烟侧流烟气中生物碱的气相色谱-火焰离子化/串联质谱检测方法 |
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US10918127B2 (en) * | 2016-09-27 | 2021-02-16 | Bond Street Manufacturing Llc | Vaporizable tobacco wax compositions and container thereof |
US20190309317A1 (en) * | 2016-12-21 | 2019-10-10 | Altria Client Services Llc | Compositions and methods for producing tobacco plants and products having altered alkaloid levels |
CA3026911A1 (en) | 2017-12-13 | 2019-06-13 | Mymd Pharmaceuticals, Inc. | Genetically modified tobacco |
CN109007950B (zh) * | 2018-05-25 | 2021-02-19 | 吉首大学 | 一种n-亚硝胺毒物复合印迹薄片的制备方法及应用 |
US10897925B2 (en) | 2018-07-27 | 2021-01-26 | Joseph Pandolfino | Articles and formulations for smoking products and vaporizers |
US20200035118A1 (en) | 2018-07-27 | 2020-01-30 | Joseph Pandolfino | Methods and products to facilitate smokers switching to a tobacco heating product or e-cigarettes |
CN109576279A (zh) * | 2018-11-12 | 2019-04-05 | 贵州省烟草科学研究院 | 烟草akt1-1基因及应用 |
CN114929880A (zh) * | 2019-10-10 | 2022-08-19 | 奥驰亚客户服务有限公司 | 用于生产具有改变的生物碱水平的烟草植物和制品的基于qpt工程改造的组合物和方法 |
KR20220169897A (ko) | 2021-06-21 | 2022-12-28 | 주식회사 케이티앤지 | Qpt 유전자가 조작된 식물 세포 및 이의 이용 방법 |
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- 2002-06-06 SG SG200507529-6A patent/SG132542A1/en unknown
- 2002-06-06 EA EA200400013A patent/EA200400013A1/ru unknown
- 2002-06-06 JP JP2003503030A patent/JP2004530430A/ja active Pending
- 2002-06-06 IL IL15921302A patent/IL159213A0/xx active IP Right Grant
- 2002-06-06 NZ NZ530238A patent/NZ530238A/en not_active IP Right Cessation
- 2002-06-06 HU HU0400161A patent/HUP0400161A2/hu unknown
- 2002-06-06 CA CA002449920A patent/CA2449920A1/en not_active Abandoned
- 2002-06-06 CN CNA028151739A patent/CN1638655A/zh active Pending
- 2002-06-06 PL PL02367438A patent/PL367438A1/xx unknown
- 2002-06-06 EP EP02734729A patent/EP1406518A4/en not_active Withdrawn
- 2002-06-06 MX MXPA03011385A patent/MXPA03011385A/es unknown
- 2002-06-07 TW TW091112317A patent/TWI258340B/zh not_active IP Right Cessation
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2005
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2006
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CA2449920A1 (en) | 2002-12-19 |
US20060060211A1 (en) | 2006-03-23 |
EA200400013A1 (ru) | 2004-06-24 |
JP2006304800A (ja) | 2006-11-09 |
JP2004530430A (ja) | 2004-10-07 |
US20050161056A1 (en) | 2005-07-28 |
UY27326A1 (es) | 2003-01-31 |
US20060191549A1 (en) | 2006-08-31 |
IL159213A (en) | 2006-10-31 |
EP1406518A2 (en) | 2004-04-14 |
US20060191547A1 (en) | 2006-08-31 |
US20040144397A1 (en) | 2004-07-29 |
TWI258340B (en) | 2006-07-21 |
IL159213A0 (en) | 2004-06-01 |
US6907887B2 (en) | 2005-06-21 |
KR20040019301A (ko) | 2004-03-05 |
NZ530238A (en) | 2004-08-27 |
WO2002100199A2 (en) | 2002-12-19 |
HUP0400161A2 (hu) | 2004-08-30 |
WO2002100199A3 (en) | 2003-05-01 |
PL367438A1 (en) | 2005-02-21 |
ZA200400084B (en) | 2004-10-12 |
CN1638655A (zh) | 2005-07-13 |
MXPA03011385A (es) | 2005-03-07 |
AR040059A1 (es) | 2005-03-16 |
EP1406518A4 (en) | 2006-03-29 |
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