Nothing Special   »   [go: up one dir, main page]

SG120092A1 - Process for the enzymatic preparation of enantiomer-enriched beta-amino acids - Google Patents

Process for the enzymatic preparation of enantiomer-enriched beta-amino acids

Info

Publication number
SG120092A1
SG120092A1 SG200302077A SG200302077A SG120092A1 SG 120092 A1 SG120092 A1 SG 120092A1 SG 200302077 A SG200302077 A SG 200302077A SG 200302077 A SG200302077 A SG 200302077A SG 120092 A1 SG120092 A1 SG 120092A1
Authority
SG
Singapore
Prior art keywords
enantiomer
amino acids
enzymatic preparation
beta
enriched beta
Prior art date
Application number
SG200302077A
Inventor
Harald Dr Groger
Helge Werner
Original Assignee
Degussa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Degussa filed Critical Degussa
Publication of SG120092A1 publication Critical patent/SG120092A1/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P41/00Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
    • C12P41/003Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by ester formation, lactone formation or the inverse reactions
    • C12P41/005Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by ester formation, lactone formation or the inverse reactions by esterification of carboxylic acid groups in the enantiomers or the inverse reaction
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00Preparation of nitrogen-containing organic compounds
    • C12P13/04Alpha- or beta- amino acids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Analytical Chemistry (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)

Abstract

A process for the production of enantiomer enriched N-unprotected, preferably open chain beta-aminoacids comprises enzymatic hydrolysis of an enantiomer mixture of corresponding beta-aminoacid esters with a hydrolase, whereby the hydrolysis is carried out in a two-phase system of water and an organic solvent that forms a second phase under the reaction conditions.
SG200302077A 2002-05-08 2003-04-09 Process for the enzymatic preparation of enantiomer-enriched beta-amino acids SG120092A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE10220740A DE10220740A1 (en) 2002-05-08 2002-05-08 Production of enantiomer enriched N-unprotected beta-aminoacids, useful for production of pharmaceuticals, comprises enzymatic hydrolysis of beta-aminoacid esters with hydrolase in two-phase system of water and organic solvent

Publications (1)

Publication Number Publication Date
SG120092A1 true SG120092A1 (en) 2006-03-28

Family

ID=29285247

Family Applications (1)

Application Number Title Priority Date Filing Date
SG200302077A SG120092A1 (en) 2002-05-08 2003-04-09 Process for the enzymatic preparation of enantiomer-enriched beta-amino acids

Country Status (10)

Country Link
EP (1) EP1367129B1 (en)
JP (1) JP4662694B2 (en)
KR (1) KR101043190B1 (en)
CN (1) CN1327002C (en)
AT (1) ATE435299T1 (en)
CA (1) CA2428163C (en)
DE (2) DE10220740A1 (en)
HR (1) HRP20030356A2 (en)
IL (1) IL155784A (en)
SG (1) SG120092A1 (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2853327B1 (en) * 2003-04-04 2012-07-27 Solvay PROCESS FOR THE PRODUCTION OF ENANTIOPOR BETA-AMINOACID DERIVATIVES AND ENANTIOPA BETA-AMINOACIDIC DERIVATIVES
JP4361094B2 (en) * 2003-12-10 2009-11-11 エボニック デグサ ゲーエムベーハー Method for producing enantiomerically enriched amino acids
WO2005085462A1 (en) * 2004-02-27 2005-09-15 Dsm Ip Assets B.V. Enzymatic preparation of an enantiomerically enriched beta-2-amino acids
JP4608938B2 (en) * 2004-05-12 2011-01-12 宇部興産株式会社 Process for producing optically active 3-alkyl-3-arylpropionic acid and optically active 3-alkyl-3-arylpropionic acid alkyl ester
JP4608963B2 (en) * 2004-06-22 2011-01-12 宇部興産株式会社 Process for producing optically active 3-aryl-3-hydroxypropionic acid and optically active 3-aryl-3-hydroxypropionic acid alkyl ester
JP4893308B2 (en) * 2004-10-08 2012-03-07 宇部興産株式会社 Process for producing optically active (S or R) -β-amino acid and optically active (R or S) -β-amino acid ester, and β-amino acid 2-alkoxyethyl ester and optically active (S or R) -β-amino acid 2 -Alkoxyethyl ester
DE102004057966A1 (en) * 2004-11-30 2006-06-01 Degussa Ag Method for asymmetrical enzymatic production of optically active organic compounds in microemulsion
CN101180402A (en) * 2005-05-17 2008-05-14 宇部兴产株式会社 Process for production of carboxylic acid using surfactant-modifying enzyme

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4439524A (en) * 1979-07-07 1984-03-27 Bayer Aktiengesellschaft Stereoselective resolution of phenylglycine derivatives with enzyme resins
US4636470A (en) * 1984-08-17 1987-01-13 Stauffer Chemical Company Resolution of racemates of amino acids

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4439524A (en) * 1979-07-07 1984-03-27 Bayer Aktiengesellschaft Stereoselective resolution of phenylglycine derivatives with enzyme resins
US4636470A (en) * 1984-08-17 1987-01-13 Stauffer Chemical Company Resolution of racemates of amino acids

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
TETRAHEDRON LETTERS. VOL. 41, 2000. PAGES 2697-2681 *

Also Published As

Publication number Publication date
EP1367129A2 (en) 2003-12-03
CN1327002C (en) 2007-07-18
HRP20030356A2 (en) 2004-04-30
KR20030087562A (en) 2003-11-14
CA2428163C (en) 2011-08-09
EP1367129A3 (en) 2003-12-17
CN1456676A (en) 2003-11-19
ATE435299T1 (en) 2009-07-15
CA2428163A1 (en) 2003-11-08
DE10220740A1 (en) 2003-11-27
IL155784A (en) 2010-06-30
KR101043190B1 (en) 2011-06-22
DE50311645D1 (en) 2009-08-13
EP1367129B1 (en) 2009-07-01
JP2003325197A (en) 2003-11-18
IL155784A0 (en) 2003-12-23
JP4662694B2 (en) 2011-03-30

Similar Documents

Publication Publication Date Title
WO2008108998A8 (en) Method to increase the yield and improve purification of products from transaminase reactions
ATE318926T1 (en) METHOD FOR PRODUCING CADAVERINDICARBOXYLATE AND USE THEREOF FOR PRODUCING NYLON
DE60320762D1 (en) PROCESS FOR THE PRODUCTION OF L-THREONINE USING A BACTERIUM BELONGING TO THE GENUS ESCHERICHIA
EA200500264A1 (en) MODIFIED REACTION OF PIKTE-SPENGLER AND PRODUCTS OBTAINED WITH ITS USE
EA200600827A1 (en) METHOD FOR PRODUCING HYDROCARBONS AND OXYGEN-CONTAINING COMPOUNDS FROM BIOMASS
DE502005002469D1 (en) Environmentally friendly process for the production of bio natural gas
WO2010078391A3 (en) Improvement of enzymatic hydrolysis of pretreated lignocellulose-containing material with dissolved air flotation sludge
SG120092A1 (en) Process for the enzymatic preparation of enantiomer-enriched beta-amino acids
DE602007013447D1 (en) GLUTAMIC ACIDIZED MICROORGANISM AND PROCESS FOR THE PRODUCTION OF GLUTAMIC ACID FOR HIGH EXPLOITATION
WO2008045185A3 (en) Process for the preparation of long-chain retinyl esters from short-chain retinyl esters and long-chain acids or long-chain esters employing lipases in organic solvents
DE60236014D1 (en) METHOD FOR PRODUCING INSULIN COMPOUNDS
ATE287965T1 (en) METHOD FOR PRODUCING L-PHOSPHINOTHRICIN BY ENZYMATIC TRANSAMINATION WITH ASPARTATE
Tasnádi et al. An efficient new enzymatic method for the preparation of β-aryl-β-amino acid enantiomers
ATE267265T1 (en) METHOD FOR PRODUCING OPTICALLY ACTIVE 2-OMEGA-OXOALKANICANE ACID DERIVATIVES
ATE332391T1 (en) METHOD FOR THE ENZYMATIC PRODUCTION OF ENANTIOMERO-ENRIGHED BETA-AMINO ACIDS
WO2007080599A3 (en) Enyzmatic process for debittering of protein hydro-lysate using immobilized peptidases
WO2004081220A3 (en) A process for enzymatically resolving an enantiomeric mixture of alpha-hydroxy acids
WO2004035801A3 (en) Enzymatic polymerisation of miniemulsions
HUP0401340A2 (en) Enzymatic method for the enantiomeric resolution of amino acids
DK1765770T3 (en) Process for the preparation of gabapentin
TW200516151A (en) Biocatalytic preparation of 1-cyanocyclohexaneacetic acid
WO2005017171A3 (en) Process for the production of d-amino acids
WO2004058701A3 (en) Biocatalytic preparation of enantiomerically enriched aminopentanenitrile
ATE423215T1 (en) METHOD FOR PRODUCING LYSOSPHINGOLIPIDS
TW200636072A (en) A method for producing l-lactic acid