SG120092A1 - Process for the enzymatic preparation of enantiomer-enriched beta-amino acids - Google Patents
Process for the enzymatic preparation of enantiomer-enriched beta-amino acidsInfo
- Publication number
- SG120092A1 SG120092A1 SG200302077A SG200302077A SG120092A1 SG 120092 A1 SG120092 A1 SG 120092A1 SG 200302077 A SG200302077 A SG 200302077A SG 200302077 A SG200302077 A SG 200302077A SG 120092 A1 SG120092 A1 SG 120092A1
- Authority
- SG
- Singapore
- Prior art keywords
- enantiomer
- amino acids
- enzymatic preparation
- beta
- enriched beta
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P41/00—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
- C12P41/003—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by ester formation, lactone formation or the inverse reactions
- C12P41/005—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by ester formation, lactone formation or the inverse reactions by esterification of carboxylic acid groups in the enantiomers or the inverse reaction
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
- C12P13/04—Alpha- or beta- amino acids
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Genetics & Genomics (AREA)
- General Chemical & Material Sciences (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Analytical Chemistry (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Enzymes And Modification Thereof (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
A process for the production of enantiomer enriched N-unprotected, preferably open chain beta-aminoacids comprises enzymatic hydrolysis of an enantiomer mixture of corresponding beta-aminoacid esters with a hydrolase, whereby the hydrolysis is carried out in a two-phase system of water and an organic solvent that forms a second phase under the reaction conditions.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE10220740A DE10220740A1 (en) | 2002-05-08 | 2002-05-08 | Production of enantiomer enriched N-unprotected beta-aminoacids, useful for production of pharmaceuticals, comprises enzymatic hydrolysis of beta-aminoacid esters with hydrolase in two-phase system of water and organic solvent |
Publications (1)
Publication Number | Publication Date |
---|---|
SG120092A1 true SG120092A1 (en) | 2006-03-28 |
Family
ID=29285247
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG200302077A SG120092A1 (en) | 2002-05-08 | 2003-04-09 | Process for the enzymatic preparation of enantiomer-enriched beta-amino acids |
Country Status (10)
Country | Link |
---|---|
EP (1) | EP1367129B1 (en) |
JP (1) | JP4662694B2 (en) |
KR (1) | KR101043190B1 (en) |
CN (1) | CN1327002C (en) |
AT (1) | ATE435299T1 (en) |
CA (1) | CA2428163C (en) |
DE (2) | DE10220740A1 (en) |
HR (1) | HRP20030356A2 (en) |
IL (1) | IL155784A (en) |
SG (1) | SG120092A1 (en) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2853327B1 (en) * | 2003-04-04 | 2012-07-27 | Solvay | PROCESS FOR THE PRODUCTION OF ENANTIOPOR BETA-AMINOACID DERIVATIVES AND ENANTIOPA BETA-AMINOACIDIC DERIVATIVES |
EP1692084B1 (en) * | 2003-12-10 | 2007-05-09 | Degussa GmbH | Process for the preparation of enantiomerically enriched amino acids |
WO2005085462A1 (en) * | 2004-02-27 | 2005-09-15 | Dsm Ip Assets B.V. | Enzymatic preparation of an enantiomerically enriched beta-2-amino acids |
JP4608938B2 (en) * | 2004-05-12 | 2011-01-12 | 宇部興産株式会社 | Process for producing optically active 3-alkyl-3-arylpropionic acid and optically active 3-alkyl-3-arylpropionic acid alkyl ester |
JP4608963B2 (en) * | 2004-06-22 | 2011-01-12 | 宇部興産株式会社 | Process for producing optically active 3-aryl-3-hydroxypropionic acid and optically active 3-aryl-3-hydroxypropionic acid alkyl ester |
JP4893308B2 (en) | 2004-10-08 | 2012-03-07 | 宇部興産株式会社 | Process for producing optically active (S or R) -β-amino acid and optically active (R or S) -β-amino acid ester, and β-amino acid 2-alkoxyethyl ester and optically active (S or R) -β-amino acid 2 -Alkoxyethyl ester |
DE102004057966A1 (en) * | 2004-11-30 | 2006-06-01 | Degussa Ag | Method for asymmetrical enzymatic production of optically active organic compounds in microemulsion |
JPWO2006123689A1 (en) * | 2005-05-17 | 2008-12-25 | 宇部興産株式会社 | Method for producing carboxylic acid using surfactant-modifying enzyme |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4439524A (en) * | 1979-07-07 | 1984-03-27 | Bayer Aktiengesellschaft | Stereoselective resolution of phenylglycine derivatives with enzyme resins |
US4636470A (en) * | 1984-08-17 | 1987-01-13 | Stauffer Chemical Company | Resolution of racemates of amino acids |
-
2002
- 2002-05-08 DE DE10220740A patent/DE10220740A1/en not_active Withdrawn
-
2003
- 2003-04-09 SG SG200302077A patent/SG120092A1/en unknown
- 2003-05-06 HR HR20030356A patent/HRP20030356A2/en not_active Application Discontinuation
- 2003-05-06 IL IL155784A patent/IL155784A/en not_active IP Right Cessation
- 2003-05-07 CA CA2428163A patent/CA2428163C/en not_active Expired - Fee Related
- 2003-05-07 KR KR1020030028856A patent/KR101043190B1/en not_active IP Right Cessation
- 2003-05-07 AT AT03010226T patent/ATE435299T1/en not_active IP Right Cessation
- 2003-05-07 CN CNB031234283A patent/CN1327002C/en not_active Expired - Fee Related
- 2003-05-07 DE DE50311645T patent/DE50311645D1/en not_active Expired - Lifetime
- 2003-05-07 EP EP03010226A patent/EP1367129B1/en not_active Expired - Lifetime
- 2003-05-08 JP JP2003130565A patent/JP4662694B2/en not_active Expired - Fee Related
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4439524A (en) * | 1979-07-07 | 1984-03-27 | Bayer Aktiengesellschaft | Stereoselective resolution of phenylglycine derivatives with enzyme resins |
US4636470A (en) * | 1984-08-17 | 1987-01-13 | Stauffer Chemical Company | Resolution of racemates of amino acids |
Non-Patent Citations (1)
Title |
---|
TETRAHEDRON LETTERS. VOL. 41, 2000. PAGES 2697-2681 * |
Also Published As
Publication number | Publication date |
---|---|
EP1367129B1 (en) | 2009-07-01 |
ATE435299T1 (en) | 2009-07-15 |
DE50311645D1 (en) | 2009-08-13 |
JP2003325197A (en) | 2003-11-18 |
DE10220740A1 (en) | 2003-11-27 |
CA2428163A1 (en) | 2003-11-08 |
IL155784A0 (en) | 2003-12-23 |
JP4662694B2 (en) | 2011-03-30 |
CN1327002C (en) | 2007-07-18 |
KR101043190B1 (en) | 2011-06-22 |
EP1367129A2 (en) | 2003-12-03 |
IL155784A (en) | 2010-06-30 |
HRP20030356A2 (en) | 2004-04-30 |
CA2428163C (en) | 2011-08-09 |
KR20030087562A (en) | 2003-11-14 |
EP1367129A3 (en) | 2003-12-17 |
CN1456676A (en) | 2003-11-19 |
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