SG11202109554XA - Neuroprotective gene therapy targeting the akt pathway - Google Patents
Neuroprotective gene therapy targeting the akt pathwayInfo
- Publication number
- SG11202109554XA SG11202109554XA SG11202109554XA SG11202109554XA SG11202109554XA SG 11202109554X A SG11202109554X A SG 11202109554XA SG 11202109554X A SG11202109554X A SG 11202109554XA SG 11202109554X A SG11202109554X A SG 11202109554XA SG 11202109554X A SG11202109554X A SG 11202109554XA
- Authority
- SG
- Singapore
- Prior art keywords
- gene therapy
- akt pathway
- therapy targeting
- neuroprotective gene
- neuroprotective
- Prior art date
Links
- 238000001415 gene therapy Methods 0.000 title 1
- 230000000324 neuroprotective effect Effects 0.000 title 1
- 230000037361 pathway Effects 0.000 title 1
- 230000008685 targeting Effects 0.000 title 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
- A61K48/005—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy characterised by an aspect of the 'active' part of the composition delivered, i.e. the nucleic acid delivered
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
- C12N9/1205—Phosphotransferases with an alcohol group as acceptor (2.7.1), e.g. protein kinases
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2217/00—Genetically modified animals
- A01K2217/07—Animals genetically altered by homologous recombination
- A01K2217/072—Animals genetically altered by homologous recombination maintaining or altering function, i.e. knock in
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2227/00—Animals characterised by species
- A01K2227/10—Mammal
- A01K2227/105—Murine
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2267/00—Animals characterised by purpose
- A01K2267/03—Animal model, e.g. for test or diseases
- A01K2267/0306—Animal model for genetic diseases
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2750/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssDNA viruses
- C12N2750/00011—Details
- C12N2750/14011—Parvoviridae
- C12N2750/14111—Dependovirus, e.g. adenoassociated viruses
- C12N2750/14141—Use of virus, viral particle or viral elements as a vector
- C12N2750/14143—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y207/00—Transferases transferring phosphorus-containing groups (2.7)
- C12Y207/11—Protein-serine/threonine kinases (2.7.11)
- C12Y207/11001—Non-specific serine/threonine protein kinase (2.7.11.1), i.e. casein kinase or checkpoint kinase
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Plant Pathology (AREA)
- Virology (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Ophthalmology & Optometry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201962813587P | 2019-03-04 | 2019-03-04 | |
US201962821705P | 2019-03-21 | 2019-03-21 | |
PCT/US2020/020832 WO2020180886A1 (en) | 2019-03-04 | 2020-03-03 | Neuroprotective gene therapy targeting the akt pathway |
Publications (1)
Publication Number | Publication Date |
---|---|
SG11202109554XA true SG11202109554XA (en) | 2021-09-29 |
Family
ID=72337003
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG11202109554XA SG11202109554XA (en) | 2019-03-04 | 2020-03-03 | Neuroprotective gene therapy targeting the akt pathway |
Country Status (9)
Country | Link |
---|---|
US (1) | US20220143217A1 (en) |
EP (1) | EP3934699A4 (en) |
JP (1) | JP2022524747A (en) |
KR (1) | KR20210141945A (en) |
CN (1) | CN113795279A (en) |
AU (1) | AU2020232692A1 (en) |
CA (1) | CA3131923A1 (en) |
SG (1) | SG11202109554XA (en) |
WO (1) | WO2020180886A1 (en) |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9828375D0 (en) * | 1998-12-22 | 1999-02-17 | Janssen Pharmaceutica Nv | Human akt-3 |
US6881555B2 (en) * | 1999-03-19 | 2005-04-19 | Aventis Pharmaceuticals Inc. | AKT nucleic acids, polypeptides, and uses thereof |
AR053272A1 (en) * | 2005-05-11 | 2007-04-25 | Hoffmann La Roche | DETERMINATION OF RESPONSIVES TO CHEMOTHERAPY |
WO2012158757A1 (en) * | 2011-05-16 | 2012-11-22 | The Trustees Of The University Of Pennsylvania | Proviral plasmids for production of recombinant adeno-associated virus |
US20160175361A1 (en) * | 2014-03-14 | 2016-06-23 | Advanced Cell Technology, Inc. | Photoreceptors and photoreceptor progenitors produced from pluripotent stem cells |
MX2016007278A (en) * | 2013-12-06 | 2016-09-16 | Inserm (Institut Nat De La Santé Et De La Rech Médicale) | Methods and pharmaceutical compositions for expressing a polynucleotide of interest in the retinal pigment epithelium of a subject. |
PT3628334T (en) * | 2014-03-21 | 2023-09-26 | Genzyme Corp | Gene therapy for retinitis pigmentosa |
-
2020
- 2020-03-03 KR KR1020217031245A patent/KR20210141945A/en unknown
- 2020-03-03 JP JP2021552552A patent/JP2022524747A/en active Pending
- 2020-03-03 CA CA3131923A patent/CA3131923A1/en active Pending
- 2020-03-03 AU AU2020232692A patent/AU2020232692A1/en active Pending
- 2020-03-03 SG SG11202109554XA patent/SG11202109554XA/en unknown
- 2020-03-03 EP EP20765810.5A patent/EP3934699A4/en active Pending
- 2020-03-03 WO PCT/US2020/020832 patent/WO2020180886A1/en unknown
- 2020-03-03 US US17/435,205 patent/US20220143217A1/en active Pending
- 2020-03-03 CN CN202080033680.0A patent/CN113795279A/en active Pending
Also Published As
Publication number | Publication date |
---|---|
CA3131923A1 (en) | 2020-09-10 |
WO2020180886A1 (en) | 2020-09-10 |
JP2022524747A (en) | 2022-05-10 |
US20220143217A1 (en) | 2022-05-12 |
EP3934699A4 (en) | 2022-12-21 |
KR20210141945A (en) | 2021-11-23 |
CN113795279A (en) | 2021-12-14 |
AU2020232692A1 (en) | 2021-09-30 |
EP3934699A1 (en) | 2022-01-12 |
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