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SG11202108863WA - Crystalline pyrimidinyl-3,8-diazabicyclo[3.2.1]octanylmethanone compound and use thereof - Google Patents

Crystalline pyrimidinyl-3,8-diazabicyclo[3.2.1]octanylmethanone compound and use thereof

Info

Publication number
SG11202108863WA
SG11202108863WA SG11202108863WA SG11202108863WA SG11202108863WA SG 11202108863W A SG11202108863W A SG 11202108863WA SG 11202108863W A SG11202108863W A SG 11202108863WA SG 11202108863W A SG11202108863W A SG 11202108863WA SG 11202108863W A SG11202108863W A SG 11202108863WA
Authority
SG
Singapore
Prior art keywords
octanylmethanone
diazabicyclo
pyrimidinyl
crystalline
compound
Prior art date
Application number
SG11202108863WA
Inventor
Xiaojing Yang
Amanda Patrice Surajhie Samuel
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of SG11202108863WA publication Critical patent/SG11202108863WA/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/08—Bridged systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13—Crystalline forms, e.g. polymorphs

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Dermatology (AREA)
  • Rheumatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pain & Pain Management (AREA)
  • Ophthalmology & Optometry (AREA)
SG11202108863WA 2019-02-15 2020-02-12 Crystalline pyrimidinyl-3,8-diazabicyclo[3.2.1]octanylmethanone compound and use thereof SG11202108863WA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201962806180P 2019-02-15 2019-02-15
PCT/IB2020/051128 WO2020165788A1 (en) 2019-02-15 2020-02-12 Crystalline pyrimidinyl-3,8-diazabicyclo[3.2.1]octanylmethanone compound and use thereof

Publications (1)

Publication Number Publication Date
SG11202108863WA true SG11202108863WA (en) 2021-09-29

Family

ID=69726639

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11202108863WA SG11202108863WA (en) 2019-02-15 2020-02-12 Crystalline pyrimidinyl-3,8-diazabicyclo[3.2.1]octanylmethanone compound and use thereof

Country Status (13)

Country Link
US (1) US20220144846A1 (en)
EP (1) EP3924355A1 (en)
JP (1) JP7561497B2 (en)
KR (2) KR20210114470A (en)
CN (1) CN113646310A (en)
AR (1) AR118099A1 (en)
AU (1) AU2020222083B2 (en)
BR (1) BR112021015951A2 (en)
CA (1) CA3130034C (en)
MX (1) MX2021009761A (en)
SG (1) SG11202108863WA (en)
TW (1) TWI820301B (en)
WO (1) WO2020165788A1 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN116802183A (en) * 2020-06-09 2023-09-22 苏州晶云药物科技股份有限公司 Novel crystal form of para-toluenesulfonate of diazabicyclo compound and preparation method thereof
CN114835717A (en) * 2021-02-01 2022-08-02 杭州领业医药科技有限公司 Brepocitinib tosylate crystal form, preparation method and application thereof
CN113461687B (en) * 2021-08-10 2022-04-19 四川大学华西医院 2, 8-aza- [4,5] decaspirocyclic ketone derivative and preparation method and application thereof

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3773919A (en) 1969-10-23 1973-11-20 Du Pont Polylactide-drug mixtures
US4485045A (en) 1981-07-06 1984-11-27 Research Corporation Synthetic phosphatidyl cholines useful in forming liposomes
US4544545A (en) 1983-06-20 1985-10-01 Trustees University Of Massachusetts Liposomes containing modified cholesterol for organ targeting
US5013556A (en) 1989-10-20 1991-05-07 Liposome Technology, Inc. Liposomes with enhanced circulation time
MA38347A1 (en) 2013-02-22 2017-10-31 Pfizer Pyrrolo [2,3-d] pyrimidine derivatives as inhibitors of janus kinases (jak)
NO2721710T3 (en) * 2014-08-21 2018-03-31
EP3773593B1 (en) * 2018-03-30 2024-05-15 Incyte Corporation Treatment of hidradenitis suppurativa using jak inhibitors

Also Published As

Publication number Publication date
KR20240116855A (en) 2024-07-30
TWI820301B (en) 2023-11-01
US20220144846A1 (en) 2022-05-12
CA3130034A1 (en) 2020-08-20
AU2020222083A1 (en) 2021-09-02
AR118099A1 (en) 2021-09-15
BR112021015951A2 (en) 2021-10-05
KR20210114470A (en) 2021-09-23
TW202045511A (en) 2020-12-16
AU2020222083B2 (en) 2022-11-17
CN113646310A (en) 2021-11-12
JP7561497B2 (en) 2024-10-04
CA3130034C (en) 2023-12-19
WO2020165788A1 (en) 2020-08-20
JP2020138960A (en) 2020-09-03
MX2021009761A (en) 2021-12-15
EP3924355A1 (en) 2021-12-22

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