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SG11202108519TA - Thioeno[3,2-b] pyridin-7-amine compounds for treating familial dysautonomia - Google Patents

Thioeno[3,2-b] pyridin-7-amine compounds for treating familial dysautonomia

Info

Publication number
SG11202108519TA
SG11202108519TA SG11202108519TA SG11202108519TA SG11202108519TA SG 11202108519T A SG11202108519T A SG 11202108519TA SG 11202108519T A SG11202108519T A SG 11202108519TA SG 11202108519T A SG11202108519T A SG 11202108519TA SG 11202108519T A SG11202108519T A SG 11202108519TA
Authority
SG
Singapore
Prior art keywords
thioeno
pyridin
amine compounds
familial dysautonomia
treating familial
Prior art date
Application number
SG11202108519TA
Inventor
Nanjing Zhang
Michael Arnold
Amal Dakka
Gary Karp
Tom Luong
Jana Narasimhan
Nikolai Naryshkin
Jiashi Wang
Xiaoyan Zhang
Original Assignee
Ptc Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ptc Therapeutics Inc filed Critical Ptc Therapeutics Inc
Publication of SG11202108519TA publication Critical patent/SG11202108519TA/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D495/00Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4365Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system having sulfur as a ring hetero atom, e.g. ticlopidine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Epidemiology (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
SG11202108519TA 2019-02-13 2020-02-10 Thioeno[3,2-b] pyridin-7-amine compounds for treating familial dysautonomia SG11202108519TA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201962805283P 2019-02-13 2019-02-13
PCT/US2020/017430 WO2020167628A1 (en) 2019-02-13 2020-02-10 Thioeno[3,2-b] pyridin-7-amine compounds for treating familial dysautonomia

Publications (1)

Publication Number Publication Date
SG11202108519TA true SG11202108519TA (en) 2021-09-29

Family

ID=69960696

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11202108519TA SG11202108519TA (en) 2019-02-13 2020-02-10 Thioeno[3,2-b] pyridin-7-amine compounds for treating familial dysautonomia

Country Status (16)

Country Link
US (1) US20220135586A1 (en)
EP (1) EP3924049A1 (en)
JP (1) JP2022520822A (en)
KR (1) KR20210137040A (en)
CN (1) CN113795304A (en)
AU (1) AU2020222881A1 (en)
BR (1) BR112021015853A2 (en)
CA (1) CA3129067A1 (en)
CL (1) CL2021002137A1 (en)
CO (1) CO2021010598A2 (en)
EA (1) EA202192170A1 (en)
IL (1) IL285399A (en)
MX (1) MX2021009667A (en)
PE (1) PE20220139A1 (en)
SG (1) SG11202108519TA (en)
WO (1) WO2020167628A1 (en)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2022013856A (en) 2020-05-13 2023-04-05 Chdi Foundation Inc Htt modulators for treating huntington's disease.
WO2022155427A1 (en) * 2021-01-14 2022-07-21 Georgetown University Usp13 inhibitors and methods of use thereof
CN112920053B (en) * 2021-02-01 2022-07-01 暨明医药科技(苏州)有限公司 Preparation method of chiral alpha-methyl aromatic ethylamine
US20240051968A1 (en) * 2021-02-05 2024-02-15 Ptc Therapeutics, Inc. Methods for treating spinocerebellar ataxia type 3
WO2022169868A1 (en) * 2021-02-05 2022-08-11 Ptc Therapeutics Inc. Compounds for treating spinocerebellar ataxia type 3
WO2022253294A1 (en) 2021-06-03 2022-12-08 江苏恒瑞医药股份有限公司 Pyridone compound having integrase inhibitory activity and pharmaceutical use thereof
EP4398987A1 (en) * 2021-09-07 2024-07-17 PTC Therapeutics, Inc. Methods for treating neurogenerative diseases
EP4426708A1 (en) 2021-11-04 2024-09-11 Skyhawk Therapeutics, Inc. Triazine amino derivatives for treating sca3
WO2023212239A1 (en) 2022-04-27 2023-11-02 Skyhawk Therapeutics, Inc. Compositions useful for modulating splicing
WO2023220439A1 (en) 2022-05-12 2023-11-16 Skyhawk Therapeutics, Inc. Compositions useful for modulating splicing
WO2023250316A1 (en) * 2022-06-22 2023-12-28 Ptc Therapeutics, Inc. Compounds for treating spinocerebellar ataxia type 3
WO2024036143A2 (en) * 2022-08-09 2024-02-15 Ptc Therapeutics, Inc. Methods for modulating rna splicing

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2015005491A1 (en) * 2013-07-12 2015-01-15 国立大学法人京都大学 Method for screening substance capable of inhibiting abnormal splicing causative of onset or progress of disease
AU2016206589B2 (en) * 2015-01-16 2020-09-10 The General Hospital Corporation Compounds for improving mRNA splicing

Also Published As

Publication number Publication date
EP3924049A1 (en) 2021-12-22
JP2022520822A (en) 2022-04-01
CA3129067A1 (en) 2020-08-20
CO2021010598A2 (en) 2021-08-30
PE20220139A1 (en) 2022-01-27
US20220135586A1 (en) 2022-05-05
BR112021015853A2 (en) 2021-10-05
CL2021002137A1 (en) 2022-02-25
MX2021009667A (en) 2021-12-10
IL285399A (en) 2021-09-30
KR20210137040A (en) 2021-11-17
WO2020167628A1 (en) 2020-08-20
CN113795304A (en) 2021-12-14
AU2020222881A1 (en) 2021-09-09
EA202192170A1 (en) 2021-11-15

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