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SG11201810286WA - Variable diameter bioreactors - Google Patents

Variable diameter bioreactors

Info

Publication number
SG11201810286WA
SG11201810286WA SG11201810286WA SG11201810286WA SG11201810286WA SG 11201810286W A SG11201810286W A SG 11201810286WA SG 11201810286W A SG11201810286W A SG 11201810286WA SG 11201810286W A SG11201810286W A SG 11201810286WA SG 11201810286W A SG11201810286W A SG 11201810286WA
Authority
SG
Singapore
Prior art keywords
international
diameter
pct
applicant
rule
Prior art date
Application number
SG11201810286WA
Inventor
Michael Mietzner
Rajesh Beri
Edward Gunderson
Original Assignee
Lonza Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lonza Ag filed Critical Lonza Ag
Publication of SG11201810286WA publication Critical patent/SG11201810286WA/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00—Constructional details, e.g. recesses, hinges
    • C12M23/02—Form or structure of the vessel
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00—Constructional details, e.g. recesses, hinges
    • C12M23/02—Form or structure of the vessel
    • C12M23/14—Bags
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00—Constructional details, e.g. recesses, hinges
    • C12M23/28—Constructional details, e.g. recesses, hinges disposable or single use
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M27/00—Means for mixing, agitating or circulating fluids in the vessel
    • C12M27/02—Stirrer or mobile mixing elements
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/48—Automatic or computerized control
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M43/00—Combinations of bioreactors or fermenters with other apparatus
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/005—Glycopeptides, glycoproteins

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Sustainable Development (AREA)
  • Biomedical Technology (AREA)
  • Clinical Laboratory Science (AREA)
  • Analytical Chemistry (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Computer Hardware Design (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Materials For Medical Uses (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Separation Using Semi-Permeable Membranes (AREA)
  • Prostheses (AREA)

Abstract

INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property 11111111111111111111111111111111111111111111111111111111111111111111111111111 Organization International Bureau (10) International Publication Number 0 (43) International Publication Date .....0\"\"\"1 WO 2017/223269 Al 28 December 2017 (28.12.2017) WIP0 I PCT (51) International Patent Classification: (81) Designated States (unless otherwise indicated, for every C12M 3/00 (2006.01) Cl 2M 1/24 (2006.01) kind of national protection available): AE, AG, AL, AM, (21) International Application Number: AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, PCT/US2017/038670 CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, (22) International Filing Date: HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, 22 June 2017 (22.06.2017) KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, (25) Filing Language: English OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, (26) Publication Language: English SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, (30) Priority Data: TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW. 62/354,216 24 June 2016 (24.06.2016) US (84) Designated States (unless otherwise indicated, for every kind of regional protection available): ARIPO (BW, GH, (71) Applicant: LONZA LTD. [CH/CH]; Lonzastrasse, 3930 GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, Visp (CH). UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, TJ, (72) Inventors: MIETZNER, Michael; 132 Tuck Drive, Fre- TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, DK, mont, New Hampshire 03044 (US). BERI, Rajesh; 14 EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, Magnolia Drive, Westford, Massachusetts 01886 (US). MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, GUNDERSON, Edward; 8 Lucas Pond Road, Notting- TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ham, New Hampshire 03290 (US). KM, ML, MR, NE, SN, TD, TG). (74) Agent: LI, Anne E. H.; CROWELL & MORING LLP, = 1001 Pennsylvania Avenue, NW, Washington, District of = Columbia 20004 (US). = = (54) Title: VARIABLE DIAMETER BIOREACTORS = = = 1014 1014 (57) : A variable diameter bioreactor vessel is provided that includes a first vessel section having a first diameter configured to hold a liquid media and biologic = = = 1011 having diameter that is 1000 material, and a second vessel section a second greater than the first diameter such that the liquid media can be increased from a first volume to a second volume within the vessel. _— - = = = = = A 1012 1014 = -• 10108 , lolCA 1004 pq f : 1012 = - 11 C:r ; i 1012' 10100 ;1010D D3 i _ 02 1014 1002 1014 D1 1016 1012 ei ei N 1018 ei IN FIG. ,-, © ei 10 C [Continued on next page] WO 2017/223269 Al IMEDIMOMMIONMEMEEHOIIIMMEHOMEHOIMIE Declarations under Rule 4.17: — as to applicant's entitlement to apply for and be granted a patent (Rule 4.17(11)) — as to the applicant's entitlement to claim the earlier application (Rule 4.17(iii)) priority of the Published: — with international search report (Art. 21(3))
SG11201810286WA 2016-06-24 2017-06-22 Variable diameter bioreactors SG11201810286WA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201662354216P 2016-06-24 2016-06-24
PCT/US2017/038670 WO2017223269A1 (en) 2016-06-24 2017-06-22 Variable diameter bioreactors

Publications (1)

Publication Number Publication Date
SG11201810286WA true SG11201810286WA (en) 2018-12-28

Family

ID=60675910

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201810286WA SG11201810286WA (en) 2016-06-24 2017-06-22 Variable diameter bioreactors

Country Status (9)

Country Link
US (3) US10370629B2 (en)
EP (1) EP3475410A4 (en)
JP (3) JP7364334B2 (en)
KR (2) KR20190022711A (en)
CN (1) CN109312291A (en)
IL (1) IL263117B2 (en)
SG (1) SG11201810286WA (en)
TW (1) TWI808057B (en)
WO (1) WO2017223269A1 (en)

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US11787841B2 (en) 2020-05-19 2023-10-17 Inscripta, Inc. Rationally-designed mutations to the thrA gene for enhanced lysine production in E. coli
US11884924B2 (en) 2021-02-16 2024-01-30 Inscripta, Inc. Dual strand nucleic acid-guided nickase editing

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Also Published As

Publication number Publication date
US20190264151A1 (en) 2019-08-29
IL263117B1 (en) 2023-03-01
JP7364334B2 (en) 2023-10-18
TWI808057B (en) 2023-07-11
JP2024023910A (en) 2024-02-21
KR102681292B1 (en) 2024-07-03
US20170369828A1 (en) 2017-12-28
TW201802470A (en) 2018-01-16
CN109312291A (en) 2019-02-05
WO2017223269A1 (en) 2017-12-28
KR20220130248A (en) 2022-09-26
US10370629B2 (en) 2019-08-06
JP2019518470A (en) 2019-07-04
IL263117A (en) 2018-12-31
KR20190022711A (en) 2019-03-06
US11597900B2 (en) 2023-03-07
IL263117B2 (en) 2023-07-01
JP2022068345A (en) 2022-05-09
US20230183623A1 (en) 2023-06-15
EP3475410A1 (en) 2019-05-01
EP3475410A4 (en) 2020-02-12

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