SG11201804885TA - Monomaleimide-functionalized platinum compounds for cancer therapy - Google Patents
Monomaleimide-functionalized platinum compounds for cancer therapyInfo
- Publication number
- SG11201804885TA SG11201804885TA SG11201804885TA SG11201804885TA SG11201804885TA SG 11201804885T A SG11201804885T A SG 11201804885TA SG 11201804885T A SG11201804885T A SG 11201804885TA SG 11201804885T A SG11201804885T A SG 11201804885TA SG 11201804885T A SG11201804885T A SG 11201804885TA
- Authority
- SG
- Singapore
- Prior art keywords
- wien
- international
- monomaleimide
- pct
- platinum compounds
- Prior art date
Links
- 229940045985 antineoplastic platinum compound Drugs 0.000 title 1
- 238000011275 oncology therapy Methods 0.000 title 1
- 150000003058 platinum compounds Chemical class 0.000 title 1
- 230000008520 organization Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F15/00—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
- C07F15/0006—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table compounds of the platinum group
- C07F15/0086—Platinum compounds
- C07F15/0093—Platinum compounds without a metal-carbon linkage
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/555—Heterocyclic compounds containing heavy metals, e.g. hemin, hematin, melarsoprol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Hematology (AREA)
- Oncology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property -, Organization MINIIII101110101011111 HO 11111 0011111110 Ell H 11011111111111111110111111 International Bureau .. .....Yi j .... ...,,,' (10) International Publication Number (43) International Publication Date WO 2017/097986 Al 15 June 2017(15.06.2017) WIPO I PCT (51) International Patent Classification: (AT). PICHLER, Verena; Antonigasse 54/14, 1180 Wien C07F 15/00 (2006.01) A61P 35/00 (2006.01) (AT). A61K 33/24 (2006.01) (74) Agent: MEIER, JURGEN, VOSSIUS & PARTNER (No (21) International Application Number: 31); SiebertstraBe 3, 81675 Miinchen (DE). PCT/EP2016/080453 (81) Designated States (unless otherwise indicated, for every (22) International Filing Date: kind of national protection available): AE, AG, AL, AM, 9 December 2016 (09.12.2016) AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, (25) Filing Language: English BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, (26) Publication Language: English HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, (30) Priority Data: MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, 15198739.3 9 December 2015 (09.12.2015) EP NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, (71) Applicants: MEDIZINISCHE UNIVERSITAT WIEN RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, [AT/AT]; Spitalgasse 23, 1090 Wien (AT). UNI- TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, VERSITAT WIEN [AT/AT]; Universitatsring 1, 1010 ZA, ZM, ZW. Wien (AT). (84) Designated States (unless otherwise indicated, for every (72) Inventors: KOWOL, Christian; Einwanggasse 6/14, kind of regional protection available): ARIPO (BW, GH, 1140 Wien (AT). HEFFETER, Petra; Landstrasser GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, Hauptstrasse 121/2, 1030 Wien (AT). BERGER, Walter; TZ, UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, = Hiitteldorferstrasse 227/5, 1140 Wien (AT). KEPPLER, TJ, TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, Bernhard K.; Dr. Baumgartnerstrasse 18, 1291 Gaweinstal DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, (AT). MAYR, Josef; Sandauergasse 2/37, 1210 Wien LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, [Continued on next page] = _ = = = = = = = R3 R 4...---' ,-, GC t:t IN O 1 © IN Il © ei O (54) Title: MONOMALEIMIDE-FUNCTIONALIZED PLATINUM COMPOUNDS FOR CANCER THERAPY - Pt -'...'''.\" R 2 (57) : The present invention relates to novel mono- 0 maleimide-functionalized platinum compounds of formula (I), including in particular novel monomaleimide-functional- ized oxaliplatin and carboplatin derivatives, as well as their use as medicaments, particularly for the treatment or preven- tion of cancer. 1 R ( I ) O WO 2017/097986 Al 011 0 SM, TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, Published: GW, KM, ML, MR, NE, SN, Declarations under Rule 4.17: TD, TG). — with international search report (Art. 2 1 (3)) — before the expiration of the time limit for amending the — as to applicant's entitlement a patent (Rule 4.1700) to apply for and be granted claims and to be republished in the event amendments (Rule 48.2(h)) of receipt of
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP15198739 | 2015-12-09 | ||
| PCT/EP2016/080453 WO2017097986A1 (en) | 2015-12-09 | 2016-12-09 | Monomaleimide-functionalized platinum compounds for cancer therapy |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG11201804885TA true SG11201804885TA (en) | 2018-07-30 |
Family
ID=54849106
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11201804885TA SG11201804885TA (en) | 2015-12-09 | 2016-12-09 | Monomaleimide-functionalized platinum compounds for cancer therapy |
Country Status (20)
| Country | Link |
|---|---|
| US (2) | US10723748B2 (en) |
| EP (1) | EP3386997B1 (en) |
| JP (1) | JP6867652B2 (en) |
| CN (1) | CN108368143B (en) |
| AU (1) | AU2016367306B2 (en) |
| CA (1) | CA3004630A1 (en) |
| CY (1) | CY1124529T1 (en) |
| DK (1) | DK3386997T3 (en) |
| ES (1) | ES2898704T3 (en) |
| HR (1) | HRP20211466T1 (en) |
| HU (1) | HUE056897T2 (en) |
| IL (1) | IL259864B (en) |
| LT (1) | LT3386997T (en) |
| MX (1) | MX2018006953A (en) |
| PL (1) | PL3386997T3 (en) |
| PT (1) | PT3386997T (en) |
| RS (1) | RS62412B1 (en) |
| SG (1) | SG11201804885TA (en) |
| SI (1) | SI3386997T1 (en) |
| WO (1) | WO2017097986A1 (en) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106659706B (en) * | 2014-06-23 | 2020-03-20 | 普莱康治疗有限公司 | Platinum compounds, compositions and uses thereof |
| TWI794171B (en) | 2016-05-11 | 2023-03-01 | 美商滬亞生物國際有限公司 | Combination therapies of hdac inhibitors and pd-l1 inhibitors |
| TWI808055B (en) | 2016-05-11 | 2023-07-11 | 美商滬亞生物國際有限公司 | Combination therapies of hdac inhibitors and pd-1 inhibitors |
| CN109171001A (en) * | 2018-09-14 | 2019-01-11 | 上海烟草集团有限责任公司 | Application of the sodium oxalate in reducing cigarette smoke in TSNAs burst size |
| CN114163479A (en) * | 2020-09-11 | 2022-03-11 | 上海海聚生物科技有限公司 | Platinum compounds for treating cancer and preparation method thereof |
| US20230339997A1 (en) * | 2020-09-11 | 2023-10-26 | Shanghai Haiju Biological Technology Co., Ltd. | Class of platinum compounds for treating cancer, and method for preparation thereof |
| CN114539320A (en) * | 2020-11-25 | 2022-05-27 | 北京大学 | Radiation-activated tetravalent platinum complexes and the use thereof |
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| EP0102324A3 (en) | 1982-07-29 | 1984-11-07 | Ciba-Geigy Ag | Lipids and surfactants in an aqueous medium |
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-
2016
- 2016-12-09 CN CN201680072428.4A patent/CN108368143B/en active Active
- 2016-12-09 AU AU2016367306A patent/AU2016367306B2/en active Active
- 2016-12-09 DK DK16822917.7T patent/DK3386997T3/en active
- 2016-12-09 SI SI201631342T patent/SI3386997T1/en unknown
- 2016-12-09 PL PL16822917T patent/PL3386997T3/en unknown
- 2016-12-09 EP EP16822917.7A patent/EP3386997B1/en active Active
- 2016-12-09 WO PCT/EP2016/080453 patent/WO2017097986A1/en active Application Filing
- 2016-12-09 PT PT16822917T patent/PT3386997T/en unknown
- 2016-12-09 US US16/060,559 patent/US10723748B2/en active Active
- 2016-12-09 MX MX2018006953A patent/MX2018006953A/en active IP Right Grant
- 2016-12-09 HR HRP20211466TT patent/HRP20211466T1/en unknown
- 2016-12-09 IL IL259864A patent/IL259864B/en unknown
- 2016-12-09 HU HUE16822917A patent/HUE056897T2/en unknown
- 2016-12-09 SG SG11201804885TA patent/SG11201804885TA/en unknown
- 2016-12-09 RS RS20211187A patent/RS62412B1/en unknown
- 2016-12-09 JP JP2018529981A patent/JP6867652B2/en active Active
- 2016-12-09 LT LTEPPCT/EP2016/080453T patent/LT3386997T/en unknown
- 2016-12-09 CA CA3004630A patent/CA3004630A1/en active Pending
- 2016-12-09 ES ES16822917T patent/ES2898704T3/en active Active
-
2020
- 2020-06-17 US US16/904,528 patent/US11572379B2/en active Active
-
2021
- 2021-09-27 CY CY20211100840T patent/CY1124529T1/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| WO2017097986A1 (en) | 2017-06-15 |
| US11572379B2 (en) | 2023-02-07 |
| SI3386997T1 (en) | 2021-11-30 |
| HUE056897T2 (en) | 2022-03-28 |
| MX2018006953A (en) | 2019-05-16 |
| CN108368143A (en) | 2018-08-03 |
| HRP20211466T1 (en) | 2021-12-24 |
| IL259864A (en) | 2018-07-31 |
| PL3386997T3 (en) | 2021-12-13 |
| US20210002313A1 (en) | 2021-01-07 |
| AU2016367306B2 (en) | 2021-04-22 |
| LT3386997T (en) | 2021-12-10 |
| PT3386997T (en) | 2021-11-04 |
| AU2016367306A1 (en) | 2018-06-14 |
| EP3386997A1 (en) | 2018-10-17 |
| JP2018538292A (en) | 2018-12-27 |
| IL259864B (en) | 2022-07-01 |
| EP3386997B1 (en) | 2021-06-30 |
| ES2898704T3 (en) | 2022-03-08 |
| DK3386997T3 (en) | 2021-09-20 |
| JP6867652B2 (en) | 2021-05-12 |
| US20180354979A1 (en) | 2018-12-13 |
| RS62412B1 (en) | 2021-10-29 |
| CA3004630A1 (en) | 2017-06-15 |
| US10723748B2 (en) | 2020-07-28 |
| CN108368143B (en) | 2022-02-01 |
| CY1124529T1 (en) | 2022-07-22 |
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